• 15869 Citations
  • 61 h-Index
1963 …2019

Research output per year

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Research Output

2019
Open Access
2018

Gangliosides in Nerve Cell Specification

Itokazu, Y., Wang, J. & Yu, R. K., Jan 1 2018, Progress in Molecular Biology and Translational Science. Schnaar, R. L. & Lopez, P. H. H. (eds.). Elsevier B.V., p. 241-263 23 p. (Progress in Molecular Biology and Translational Science; vol. 156).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations
2017

Epigenetic regulation of ganglioside expression in neural stem cells and neuronal cells

Itokazu, Y., Tsai, Y. T. & Yu, R. K., Dec 1 2017, In : Glycoconjugate Journal. 34, 6, p. 749-756 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

Special issue: Glycobiology on stem cells ---editorial

Kawasaki, T. & Yu, R. K., Dec 1 2017, In : Glycoconjugate Journal. 34, 6, 1 p.

Research output: Contribution to journalEditorial

2016

A2B5+/GFAP+ Cells of Rat Spinal Cord Share a Similar Lipid Profile with Progenitor Cells: A Comparative Lipidomic Study

Itokazu, Y., Tajima, N., Kerosuo, L., Somerharju, P., Sariola, H., Yu, R. K. & Käkelä, R., Jul 1 2016, In : Neurochemical Research. 41, 7, p. 1527-1544 18 p.

Research output: Contribution to journalArticle

3 Scopus citations

Anti-Sulfoglucuronosyl Paragloboside Antibody: A Potential Serologic Marker of Amyotrophic Lateral Sclerosis

Li, D., Usuki, S., Quarles, B., Rivner, M. H., Ariga, T. & Yu, R. K., Sep 1 2016, In : ASN Neuro. 8, 5

Research output: Contribution to journalArticle

1 Scopus citations

Dietary isomers of sialyllactose increase ganglioside sialic acid concentrations in the corpus callosum and cerebellum and modulate the colonic microbiota of formula-fed piglets

Jacobi, S. K., Yatsunenko, T., Li, D., Dasgupta, S., Yu, R. K., Berg, B. M., Chichlowski, M. & Odle, J., Jan 1 2016, In : Journal of Nutrition. 146, 2, p. 200-208 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Erratum: Novel GM1 ganglioside-like peptide mimics prevent the association of cholera toxin to human intestinal epithelial in vitro

Yu, R. K., Usuki, S., Itokazu, Y. & Wu, H. C., May 1 2016, In : Glycobiology. 26, 5, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

GM1 ganglioside is involved in epigenetic activation loci of neuronal cells

Tsai, Y. T., Itokazu, Y. & Yu, R. K., Oct 24 2016, In : Neurochemical Research. 41, 1-2, p. 107-115 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Ganglioside-dependent neural stem cell proliferation in alzheimer’s disease model mice

Koon, N. A., Itokazu, Y. & Yu, R. K., Nov 9 2015, In : ASN Neuro. 7, 6

Research output: Contribution to journalArticle

5 Scopus citations

Glycolipid Antigens in Neural Stem Cells

Itokazu, Y. & Yu, R. K., Apr 15 2015, Neural Surface Antigens: From Basic Biology Towards Biomedical Applications. Elsevier Inc., p. 91-102 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuroglycobiology: Role of glycans in neurobiology and neuroscience glycoconjugate antigens in neural stem cells

Itokazu, Y. & Yu, R. K., Jan 1 2015, Glycoscience: Biology and Medicine. Springer Japan, p. 495-504 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Novel GM1 ganglioside-like peptide mimics prevent the association of cholera toxin to human intestinal epithelial cells in vitro

Yu, R. K., Usuki, S., Itokazu, Y. & Wu, H. C., Jun 11 2015, In : Glycobiology. 26, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014
17 Scopus citations

A new approach to ELISA-based anti-glycolipid antibody evaluation of highly adhesive serum samples

Usuki, S., O'Brien, D., Rivner, M. H. & Yu, R. K., Jun 2014, In : Journal of Immunological Methods. 408, p. 52-63 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Epigenetic activation of mouse ganglioside synthase genes: Implications for neurogenesis

Tsai, Y. T. & Yu, R. K., Jan 1 2014, In : Journal of Neurochemistry. 128, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Ganglioside GD3 is required for neurogenesis and long-term maintenance of neural stem cells in the postnatal mouse brain

Wang, J., Cheng, A., Wakade, C. & Yu, R. K., Oct 8 2014, In : Journal of Neuroscience. 34, 41, p. 13790-13800 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Glycolipid and glycoprotein expression during neural development

Yu, R. K. & Itokazu, Y., 2014, In : Advances in neurobiology. 9, p. 185-222 38 p.

Research output: Contribution to journalArticle

2013

Antibodies to heteromeric glycolipid complexes in guillain-barré syndrome

Rinaldi, S., Brennan, K. M., Kalna, G., Walgaard, C., Van Doorn, P., Jacobs, B. C., Yu, R. K., Mansson, J. E., Goodyear, C. S. & Willison, H. J., Dec 16 2013, In : PloS one. 8, 12, e82337.

Research output: Contribution to journalArticle

36 Scopus citations

Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy

Galban-Horcajo, F., Fitzpatrick, A. M., Hutton, A. J., Dunn, S. M., Kalna, G., Brennan, K. M., Rinaldi, S., Yu, R. K., Goodyear, C. S. & Willison, H. J., Jan 1 2013, In : European Journal of Neurology. 20, 1, p. 62-70 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Anti-Chol-1 Antigen, GQ1bα, Antibodies Are Associated with Alzheimer's Disease

Ariga, T., Kubota, M., Nakane, M., Oguro, K., Yu, R. K. & Ando, S., May 23 2013, In : PloS one. 8, 5, e63326.

Research output: Contribution to journalArticle

8 Scopus citations

Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: Expression of elevated levels of a cholinergic-specific ganglioside, GT1aα

Ariga, T., Itokazu, Y., McDonald, M. P., Hirabayashi, Y., Ando, S. & Yu, R. K., Aug 7 2013, In : ASN Neuro. 5, 2, p. 141-148 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effects of amyloid β-peptides and gangliosides on mouse neural stem cells

Itokazu, Y., Kato-Negishi, M., Nakatani, Y., Ariga, T. & Yu, R. K., Oct 1 2013, In : Neurochemical Research. 38, 10, p. 2019-2027 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Human Anti-Glycosphingolipids Antibodies in Guillain-Barré Syndrome

Yu, R. K. & Usuki, S., Dec 1 2013, Autoantibodies: Third Edition. Elsevier B.V., p. 581-594 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

55 Scopus citations

O-acetylated n-acetylneuraminic acid as a novel target for therapy in human pre-b acute lymphoblastic leukemia

Parameswaran, R., Lim, M., Arutyunyan, A., Abdel-Azim, H., Hurtz, C., Lau, K., Müschen, M., Yu, R. K., von Itzstein, M., Heisterkamp, N. & Groffen, J., Jun 25 2013, In : Journal of Experimental Medicine. 210, 4, p. 805-819 15 p.

Research output: Contribution to journalArticle

17 Scopus citations
2012

Anti-glycolipid antibodies in guillain-barré syndrome and related neuropathies: Therapeutic strategies for disease treatment

Yu, R. K., Usuki, S. & Ariga, T., Oct 1 2012, Anticarbohydrate Antibodies: From Molecular Basis to Clinical Application. Springer-Verlag Wien, Vol. 9783709108703. p. 327-359 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Functional roles of gangliosides in Neurodevelopment: An overview of recent advances

Yu, R. K., Tsai, Y. T. & Ariga, T., Jun 1 2012, In : Neurochemical Research. 37, 6, p. 1230-1244 15 p.

Research output: Contribution to journalReview article

102 Scopus citations

Lewis X-carrying N-glycans regulate the proliferation of mouse embryonic neural stem cells via the notch signaling pathway

Yagi, H., Saito, T., Yanagisawa, M., Yu, R. K. & Kato, K., Jul 13 2012, In : Journal of Biological Chemistry. 287, 29, p. 24356-24364 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Pathobiochemical effect of acylated steryl-β-glucoside on aggregation and cytotoxicity of α-synuclein

Usuki, S., Kamitani, T., Matsuo, Y. & Yu, R. K., Jun 1 2012, In : Neurochemical Research. 37, 6, p. 1261-1266 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Preface to the special issue honoring Bob Ledeen

Yu, R. K., Jun 1 2012, In : Neurochemical Research. 37, 6, p. 1133-1136 4 p.

Research output: Contribution to journalEditorial

2011

Expression of GD2 and GD3 gangliosides in human embryonic neural stem cells

Yanagisawa, M., Yoshimura, S. & Yu, R. K., Apr 7 2011, In : ASN Neuro. 3, 2

Research output: Contribution to journalArticle

34 Scopus citations

Genome-wide target profiling of piggyBac and Tol2 in HEK 293: Pros and cons for gene discovery and gene therapy

Meir, Y. J. J., Weirauch, M. T., Yang, H. S., Chung, P. C., Yu, R. K. & Wu, S. C. Y., Mar 30 2011, In : BMC Biotechnology. 11, 28.

Research output: Contribution to journalArticle

49 Scopus citations

Histone acetylation-mediated glycosyltransferase gene regulation in mouse brain during development

Suzuki, Y., Yanagisawa, M., Ariga, T. & Yu, R. K., Mar 1 2011, In : Journal of Neurochemistry. 116, 5, p. 874-880 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

IGF-1 induction by acylated steryl β-glucosides found in a pre-germinated brown rice diet reduces oxidative stress in streptozotocin-induced diabetes

Usuki, S., Tsai, Y. Y., Morikawa, K., Nonaka, S., Okuhara, Y., Kise, M. & Yu, R. K., Dec 14 2011, In : PloS one. 6, 12, e28693.

Research output: Contribution to journalArticle

16 Scopus citations

Pathological roles of ganglioside mimicry in guillain-barré syndrome and related neuropathies

Yu, R. K., Ariga, T., Usuki, S. & Kaida, K. I., Dec 19 2011, The Molecular Immunology of Complex Carbohydrates-3. Wu, A. (ed.). p. 349-365 17 p. (Advances in Experimental Medicine and Biology; vol. 705).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

13 Scopus citations

Structures, biosynthesis, and functions of gangliosides-an overview

Yu, R. K., Tsai, Y. T., Ariga, T. & Yanagisawa, M., Sep 27 2011, In : Journal of Oleo Science. 60, 10, p. 537-544 8 p.

Research output: Contribution to journalReview article

150 Scopus citations

Sulfoglucuronosyl paragloboside promotes endothelial cell apoptosis in inflammation: Elucidation of a novel glycosphingolipid-signaling pathway

Dasgupta, S., Wang, G. & Yu, R. K., Nov 1 2011, In : Journal of Neurochemistry. 119, 4, p. 749-759 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
26 Scopus citations
2010

Characterization of GD3 ganglioside as a novel biomarker of mouse neural stem cells

Nakatani, Y., Yanagisawa, M., Suzuki, Y. & Yu, R. K., Jan 1 2010, In : Glycobiology. 20, 1, p. 78-86 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Cytotoxic effects of GM1 ganglioside and amyloid β-peptide on mouse embryonic neural stem cells

Yanagisawa, M., Ariga, T. & Yu, R. K., 2010, In : ASN Neuro. 2, 1, p. 49-56 8 p., e00029.

Research output: Contribution to journalArticle

12 Scopus citations

Development of a novel therapy for Lipo-oligosaccharide-induced experimental neuritis: Use of peptide glycomimics

Usuki, S., Taguchi, K., Gu, Y. H., Thompson, S. A. & Yu, R. K., Apr 1 2010, In : Journal of Neurochemistry. 113, 2, p. 351-362 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Ganglioside metabolism in a transgenic mouse model of alzheimer's disease: Expression of chol-1α antigens in the brain

Ariga, T., Yanagisawa, M., Wakade, C., Ando, S., Buccafusco, J. J., McDonald, M. P. & Yu, R. K., Oct 29 2010, In : ASN Neuro. 2, 4, p. 233-241 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells

Yagi, H., Yanagisawa, M., Suzuki, Y., Nakatani, Y., Ariga, T., Kato, K. & Yu, R. K., Nov 26 2010, In : Journal of Biological Chemistry. 285, 48, p. 37293-37301 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Involvement of β1-integrin up-regulation in basic fibroblast growth factor- and epidermal growth factor-induced proliferation of mouse neuroepithelial cells

Suzuki, Y., Yanagisawa, M., Yagi, H., Nakatani, Y. & Yu, R. K., Jun 11 2010, In : Journal of Biological Chemistry. 285, 24, p. 18443-18451 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Lysosome-associated membrane protein 1 is a major SSEA-1-carrier protein in mouse neural stem cells

Yagi, H., Yanagisawa, M., Kato, K. & Yu, R. K., Mar 31 2010, In : Glycobiology. 20, 8, p. 976-981 6 p., cwq054.

Research output: Contribution to journalArticle

17 Scopus citations

Membrane glycolipids in stem cells

Yu, R. K., Suzuki, Y. & Yanagisawa, M., May 1 2010, In : FEBS Letters. 584, 9, p. 1694-1699 6 p.

Research output: Contribution to journalReview article

32 Scopus citations

Novel anti-idiotype antibody therapy for lipooligosaccharide-induced experimental autoimmune neuritis: Use relevant to Guillain-Barré syndrome

Usuki, S., Taguchi, K., Thompson, S. A., Chapman, P. B. & Yu, R. K., Jun 1 2010, In : Journal of Neuroscience Research. 88, 8, p. 1651-1663 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
70 Scopus citations
2009

Antiganglioside antibodies and their pathophysiological effects on Guillain-Barré syndrome and related disorders - A review

Kaida, K., Ariga, T. & Yu, R. K., Jun 8 2009, In : Glycobiology. 19, 7, p. 676-692 17 p.

Research output: Contribution to journalReview article

83 Scopus citations