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1963 …2019

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Article
2019
Open Access
2016

A2B5+/GFAP+ Cells of Rat Spinal Cord Share a Similar Lipid Profile with Progenitor Cells: A Comparative Lipidomic Study

Itokazu, Y., Tajima, N., Kerosuo, L., Somerharju, P., Sariola, H., Yu, R. K. & Käkelä, R., Jul 1 2016, In : Neurochemical Research. 41, 7, p. 1527-1544 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

Anti-Sulfoglucuronosyl Paragloboside Antibody: A Potential Serologic Marker of Amyotrophic Lateral Sclerosis

Li, D., Usuki, S., Quarles, B., Rivner, M. H., Ariga, T. & Yu, R. K., Sep 1 2016, In : ASN Neuro. 8, 5

Research output: Contribution to journalArticle

1 Scopus citations

Dietary isomers of sialyllactose increase ganglioside sialic acid concentrations in the corpus callosum and cerebellum and modulate the colonic microbiota of formula-fed piglets

Jacobi, S. K., Yatsunenko, T., Li, D., Dasgupta, S., Yu, R. K., Berg, B. M., Chichlowski, M. & Odle, J., Jan 1 2016, In : Journal of Nutrition. 146, 2, p. 200-208 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

GM1 ganglioside is involved in epigenetic activation loci of neuronal cells

Tsai, Y. T., Itokazu, Y. & Yu, R. K., Oct 24 2016, In : Neurochemical Research. 41, 1-2, p. 107-115 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Ganglioside-dependent neural stem cell proliferation in alzheimer’s disease model mice

Koon, N. A., Itokazu, Y. & Yu, R. K., Nov 9 2015, In : ASN Neuro. 7, 6

Research output: Contribution to journalArticle

5 Scopus citations

Novel GM1 ganglioside-like peptide mimics prevent the association of cholera toxin to human intestinal epithelial cells in vitro

Yu, R. K., Usuki, S., Itokazu, Y. & Wu, H. C., Jun 11 2015, In : Glycobiology. 26, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014
17 Scopus citations

A new approach to ELISA-based anti-glycolipid antibody evaluation of highly adhesive serum samples

Usuki, S., O'Brien, D., Rivner, M. H. & Yu, R. K., Jun 2014, In : Journal of Immunological Methods. 408, p. 52-63 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Epigenetic activation of mouse ganglioside synthase genes: Implications for neurogenesis

Tsai, Y. T. & Yu, R. K., Jan 1 2014, In : Journal of Neurochemistry. 128, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Ganglioside GD3 is required for neurogenesis and long-term maintenance of neural stem cells in the postnatal mouse brain

Wang, J., Cheng, A., Wakade, C. & Yu, R. K., Oct 8 2014, In : Journal of Neuroscience. 34, 41, p. 13790-13800 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Glycolipid and glycoprotein expression during neural development

Yu, R. K. & Itokazu, Y., 2014, In : Advances in neurobiology. 9, p. 185-222 38 p.

Research output: Contribution to journalArticle

2013

Antibodies to heteromeric glycolipid complexes in guillain-barré syndrome

Rinaldi, S., Brennan, K. M., Kalna, G., Walgaard, C., Van Doorn, P., Jacobs, B. C., Yu, R. K., Mansson, J. E., Goodyear, C. S. & Willison, H. J., Dec 16 2013, In : PloS one. 8, 12, e82337.

Research output: Contribution to journalArticle

36 Scopus citations

Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy

Galban-Horcajo, F., Fitzpatrick, A. M., Hutton, A. J., Dunn, S. M., Kalna, G., Brennan, K. M., Rinaldi, S., Yu, R. K., Goodyear, C. S. & Willison, H. J., Jan 1 2013, In : European Journal of Neurology. 20, 1, p. 62-70 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Anti-Chol-1 Antigen, GQ1bα, Antibodies Are Associated with Alzheimer's Disease

Ariga, T., Kubota, M., Nakane, M., Oguro, K., Yu, R. K. & Ando, S., May 23 2013, In : PloS one. 8, 5, e63326.

Research output: Contribution to journalArticle

8 Scopus citations

Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: Expression of elevated levels of a cholinergic-specific ganglioside, GT1aα

Ariga, T., Itokazu, Y., McDonald, M. P., Hirabayashi, Y., Ando, S. & Yu, R. K., Aug 7 2013, In : ASN Neuro. 5, 2, p. 141-148 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effects of amyloid β-peptides and gangliosides on mouse neural stem cells

Itokazu, Y., Kato-Negishi, M., Nakatani, Y., Ariga, T. & Yu, R. K., Oct 1 2013, In : Neurochemical Research. 38, 10, p. 2019-2027 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
56 Scopus citations

O-acetylated n-acetylneuraminic acid as a novel target for therapy in human pre-b acute lymphoblastic leukemia

Parameswaran, R., Lim, M., Arutyunyan, A., Abdel-Azim, H., Hurtz, C., Lau, K., Müschen, M., Yu, R. K., von Itzstein, M., Heisterkamp, N. & Groffen, J., Jun 25 2013, In : Journal of Experimental Medicine. 210, 4, p. 805-819 15 p.

Research output: Contribution to journalArticle

17 Scopus citations
2012

Lewis X-carrying N-glycans regulate the proliferation of mouse embryonic neural stem cells via the notch signaling pathway

Yagi, H., Saito, T., Yanagisawa, M., Yu, R. K. & Kato, K., Jul 13 2012, In : Journal of Biological Chemistry. 287, 29, p. 24356-24364 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Pathobiochemical effect of acylated steryl-β-glucoside on aggregation and cytotoxicity of α-synuclein

Usuki, S., Kamitani, T., Matsuo, Y. & Yu, R. K., Jun 1 2012, In : Neurochemical Research. 37, 6, p. 1261-1266 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2011

Expression of GD2 and GD3 gangliosides in human embryonic neural stem cells

Yanagisawa, M., Yoshimura, S. & Yu, R. K., Apr 7 2011, In : ASN Neuro. 3, 2

Research output: Contribution to journalArticle

34 Scopus citations

Genome-wide target profiling of piggyBac and Tol2 in HEK 293: Pros and cons for gene discovery and gene therapy

Meir, Y. J. J., Weirauch, M. T., Yang, H. S., Chung, P. C., Yu, R. K. & Wu, S. C. Y., Mar 30 2011, In : BMC Biotechnology. 11, 28.

Research output: Contribution to journalArticle

49 Scopus citations

Histone acetylation-mediated glycosyltransferase gene regulation in mouse brain during development

Suzuki, Y., Yanagisawa, M., Ariga, T. & Yu, R. K., Mar 1 2011, In : Journal of Neurochemistry. 116, 5, p. 874-880 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

IGF-1 induction by acylated steryl β-glucosides found in a pre-germinated brown rice diet reduces oxidative stress in streptozotocin-induced diabetes

Usuki, S., Tsai, Y. Y., Morikawa, K., Nonaka, S., Okuhara, Y., Kise, M. & Yu, R. K., Dec 14 2011, In : PloS one. 6, 12, e28693.

Research output: Contribution to journalArticle

16 Scopus citations

Sulfoglucuronosyl paragloboside promotes endothelial cell apoptosis in inflammation: Elucidation of a novel glycosphingolipid-signaling pathway

Dasgupta, S., Wang, G. & Yu, R. K., Nov 1 2011, In : Journal of Neurochemistry. 119, 4, p. 749-759 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2010

Characterization of GD3 ganglioside as a novel biomarker of mouse neural stem cells

Nakatani, Y., Yanagisawa, M., Suzuki, Y. & Yu, R. K., Jan 1 2010, In : Glycobiology. 20, 1, p. 78-86 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Cytotoxic effects of GM1 ganglioside and amyloid β-peptide on mouse embryonic neural stem cells

Yanagisawa, M., Ariga, T. & Yu, R. K., 2010, In : ASN Neuro. 2, 1, p. 49-56 8 p., e00029.

Research output: Contribution to journalArticle

12 Scopus citations

Development of a novel therapy for Lipo-oligosaccharide-induced experimental neuritis: Use of peptide glycomimics

Usuki, S., Taguchi, K., Gu, Y. H., Thompson, S. A. & Yu, R. K., Apr 1 2010, In : Journal of Neurochemistry. 113, 2, p. 351-362 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Ganglioside metabolism in a transgenic mouse model of alzheimer's disease: Expression of chol-1α antigens in the brain

Ariga, T., Yanagisawa, M., Wakade, C., Ando, S., Buccafusco, J. J., McDonald, M. P. & Yu, R. K., Oct 29 2010, In : ASN Neuro. 2, 4, p. 233-241 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells

Yagi, H., Yanagisawa, M., Suzuki, Y., Nakatani, Y., Ariga, T., Kato, K. & Yu, R. K., Nov 26 2010, In : Journal of Biological Chemistry. 285, 48, p. 37293-37301 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Involvement of β1-integrin up-regulation in basic fibroblast growth factor- and epidermal growth factor-induced proliferation of mouse neuroepithelial cells

Suzuki, Y., Yanagisawa, M., Yagi, H., Nakatani, Y. & Yu, R. K., Jun 11 2010, In : Journal of Biological Chemistry. 285, 24, p. 18443-18451 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Lysosome-associated membrane protein 1 is a major SSEA-1-carrier protein in mouse neural stem cells

Yagi, H., Yanagisawa, M., Kato, K. & Yu, R. K., Mar 31 2010, In : Glycobiology. 20, 8, p. 976-981 6 p., cwq054.

Research output: Contribution to journalArticle

17 Scopus citations

Novel anti-idiotype antibody therapy for lipooligosaccharide-induced experimental autoimmune neuritis: Use relevant to Guillain-Barré syndrome

Usuki, S., Taguchi, K., Thompson, S. A., Chapman, P. B. & Yu, R. K., Jun 1 2010, In : Journal of Neuroscience Research. 88, 8, p. 1651-1663 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2009

Cav2.1 voltage-dependent Ca 2+ channel current is inhibited by serum from select patients with guillain-barré syndrome

Nakatani, Y., Hotta, S., Utsunomiya, I., Tanaka, K., Hoshi, K., Ariga, T., Yu, R. K., Miyatake, T. & Taguchi, K., Jan 1 2009, In : Neurochemical Research. 34, 1, p. 149-157 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Elimination of GD3 synthase improves memory and reduces amyloid-β plaque load in transgenic mice

Bernardo, A., Harrison, F. E., McCord, M., Zhao, J., Bruchey, A., Davies, S. S., Jackson Roberts, L., Mathews, P. M., Matsuoka, Y., Ariga, T., Yu, R. K., Thompson, R. & McDonald, M. P., Nov 1 2009, In : Neurobiology of Aging. 30, 11, p. 1777-1791 15 p.

Research output: Contribution to journalArticle

75 Scopus citations
39 Scopus citations

N-Glycans modulate the activation of gp130 in mouse embryonic neural precursor cells

Yanagisawa, M. & Yu, R. K., Aug 14 2009, In : Biochemical and Biophysical Research Communications. 386, 1, p. 101-104 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

O-linked β-N-acetylglucosaminylation in mouse embryonic neural precursor cells

Yanagisawa, M. & Yu, R. K., Dec 1 2009, In : Journal of Neuroscience Research. 87, 16, p. 3535-3545 11 p.

Research output: Contribution to journalArticle

24 Scopus citations
6 Scopus citations
2008

Glycosphingolipid antigens in neural tumor cell lines and anti-glycosphingolipid antibodies in sera of patients with neural tumors

Ariga, T., Suetake, K., Nakane, M., Kubota, M., Usuki, S., Kawashima, I. & Yu, R. K., Feb 1 2008, In : NeuroSignals. 16, 2-3, p. 226-234 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification and analysis of novel functional sites in human GD3-synthase

Gu, Y. & Yu, R. K., May 23 2008, In : Biochemical and Biophysical Research Communications. 370, 1, p. 67-71 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Identification of gangliosides recognized by IgG anti-GalNAc-GD1a antibodies in bovine spinal motor neurons and motor nerves

Yoshino, H., Ariga, T., Suzuki, A., Yu, R. K. & Miyatake, T., Aug 28 2008, In : Brain Research. 1227, p. 216-220 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Introduction to thematic series on sphingolipids in honor of Professor Herbert E. Carter (1910-2007)

Law, J. H. & Yu, R. K., May 1 2008, In : Journal of Lipid Research. 49, 5, p. 907-908 2 p.

Research output: Contribution to journalArticle

Structural analysis of novel bioactive acylated steryl glucosides in pre-germinated brown rice bran

Usuki, S., Ariga, T., Dasgupta, S., Kasama, T., Morikawa, K., Nonaka, S., Okuhara, Y., Kise, M. & Yu, R. K., Dec 1 2008, In : Journal of Lipid Research. 49, 10, p. 2188-2196 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Topology and patch-clamp analysis of the sodium channel in relationship to the anti-lipid A antibody in campylobacteriosis

Usuki, S., Nakatani, Y., Taguchi, K., Fujita, T., Tanabe, S., Ustunomiya, I., Gu, Y., Cawthraw, S. A., Newell, D. G., Pajaniappan, M., Thompson, S. A., Ariga, T. & Yu, R. K., Dec 8 2008, In : Journal of Neuroscience Research. 86, 15, p. 3359-3374 16 p.

Research output: Contribution to journalArticle

6 Scopus citations
2007

Chemical validation of molecular mimicry: Interaction of cholera toxin with Campylobacter lipooligosaccharides

Usuki, S., Pajaniappan, M., Thompson, S. A. & Yu, R. K., Apr 1 2007, In : Glycoconjugate Journal. 24, 2-3, p. 167-180 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Developmental changes of glycosphingolipids and expression of glycogenes in mouse brains

Ngamukote, S., Yanagisawa, M., Ariga, T., Ando, S. & Yu, R. K., Dec 1 2007, In : Journal of Neurochemistry. 103, 6, p. 2327-2341 15 p.

Research output: Contribution to journalArticle

140 Scopus citations

Effect of pre-germinated brown rice intake on diabetic neuropathy in streptozotocin-induced diabetic rats

Usuki, S., Ito, Y., Morikawa, K., Kise, M., Ariga, T., Rivner, M. & Yu, R. K., Dec 1 2007, In : Nutrition and Metabolism. 4, 25.

Research output: Contribution to journalArticle

30 Scopus citations

Inhibition of neuronal migration by JONES antibody is independent of 9-O-acetyl GD3 in GD3-synthase knockout mice

Yang, C. R., Liour, S. S., Dasgupta, S. & Yu, R. K., May 15 2007, In : Journal of Neuroscience Research. 85, 7, p. 1381-1390 10 p.

Research output: Contribution to journalArticle

9 Scopus citations