• 16030 Citations
  • 61 h-Index
1963 …2021

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Article
1999

Down-regulation of the expression of O-acetyl-GD3 by the O- acetylesterase cDNA in hamster melanoma cells: Effects on cellular proliferation, differentiation, and melanogenesis

Birklé, S., Ren, S., Slominski, A., Zeng, G., Gao, L. & Yu, R. K., 1999, In : Journal of Neurochemistry. 72, 3, p. 954-961 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

GM1 inhibits amyloid β-protein-induced cytokine release

Ariga, T. & Yu, R. K., Feb 13 1999, In : Neurochemical Research. 24, 2, p. 219-226 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Molecular cloning and expression of mouse brain sialidase

Fronda, C. L., Zeng, G., Gao, L. & Yu, R. K., May 19 1999, In : Biochemical and Biophysical Research Communications. 258, 3, p. 727-731 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Multi-enzyme kinetic analysis of glycolipid biosynthesis

Bieberich, E. & Yu, R. K., Jun 15 1999, In : Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology. 1432, 1, p. 113-124 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Myelinated dorsal root ganglion cultures activate both the alternative and classical pathways of complement

Scott-Zaki, P., Purkall, D., Bigbee, J., Ruddy, S. & Yu, R. K., Jun 1 1999, In : Journal of the Neurological Sciences. 165, 2, p. 160-169 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
1998

Antiglycolipid antibodies in motor neuropathies

Baumann, N., Harpin, M. L., Marie, Y., Lemerle, K., Chassande, B., Bouche, P., Meininger, V., Yu, R. K. & Léger, J. M., 1998, In : Annals of the New York Academy of Sciences. 845, p. 322-329 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cloning of promoter for rat GD3-synthase gene

Gao, L., Zeng, G. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

Developmental expression of rat brain GD3-and GT3-synthases

Zeng, G., Gao, L., Freischütz, B., Tokuda, A. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

GM1 ganglioside inhibits amyloid β-protein induced-cytokine release

Ariga, T. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Heterogeneity of antibody specificity in Taiwanese patients with polyneuropathy and IgM paraproteinemia

Lin, K. P., Tsai, C. P., Yamawaki, M., Ariga, T. & Yu, R. K., Jan 1 1998, In : Journal of Biomedical Science. 5, 6, p. 441-445 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Isolation and functional analysis of the promoter of the rat CMP-NeuAc:GM3 α 2,8 sialyltransferase gene

Zeng, G., Gao, L. & Yu, R. K., Apr 27 1998, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1397, 2, p. 126-130 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

On the specificity of anti-sulfoglucuronosyl glycolipid antibodies

Tokuda, A., Ariga, T., Isogai, Y., Komba, S., Kiso, M., Hasegawa, A., Tai, T. & Yu, R. K., Jan 1 1998, In : Journal of Carbohydrate Chemistry. 17, 4-5, p. 535-546 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Permanent alteration of endogenous gangliosides in neuroblastoma cells by stable transfection with antisense vector

Zeng, G., Gao, L., Li, D. D., Tokuda, A. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Regulation of ganglioside metabolism by phosphorylation and dephosphorylation

Bieberich, E., Freischütz, B., Liour, S. S. & Yu, R. K., Sep 1998, In : Journal of Neurochemistry. 71, 3, p. 972-979 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Sulfoglucuronosyl glycolipids as putative antigens for autoimmune inner ear disease

Yamawaki, M., Ariga, T., Gao, Y., Tokuda, A., Yu, J. S., Sismanis, A. & Yu, R. K., Apr 15 1998, In : Journal of Neuroimmunology. 84, 2, p. 111-116 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

The role of glycosphinglipids in neurological disorders - Mechanisms of immune action

Yu, R. K. & Ariga, T., 1998, In : Annals of the New York Academy of Sciences. 845, p. 285-306 22 p.

Research output: Contribution to journalArticle

35 Scopus citations
1997

Antibodies to glycosphingolipid antigens in patients with immune-mediated cochleovestibular disorders

Lake, G. M., Sismanis, A., Ariga, T., Yamawaki, M., Gao, Y. & Yu, R. K., Mar 1997, In : American Journal of Otology. 18, 2, p. 175-178 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Cloning, characterization, and expression of human ceramide galactosyltransferase cDNA

Kapitonov, D. & Yu, R. K., Mar 17 1997, In : Biochemical and Biophysical Research Communications. 232, 2, p. 449-453 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cloning of the cDNA coding for rat brain CMP-NeuAc:GD3 α2-8 sialyltransferase

Zeng, G., Gao, L. & Yu, R. K., Mar 10 1997, In : Gene. 187, 1, p. 131-134 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Ganglioside GD3 and GD3-lactone mediated regulation of the intermolecular organization in mixed monolayers with dipalmitoylphosphatidylcholine

Maggio, B., Ariga, T., Calderón, R. O. & Yu, R. K., Nov 19 1997, In : Chemistry and Physics of Lipids. 90, 1-2, p. 1-10 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Glycosyltransferase activities in cultured endothelial cells of bovine brain microvascular origin

Kanda, T., Ariga, T., Yamawaki, M., Yoshino, H., Gu, X. B. & Yu, R. K., Jan 1 1997, In : Neurochemical Research. 22, 4, p. 463-466 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Heritability and biochemistry of gangliosidosis in emus (Dromaius novaehollandiae)

Bermudez, A. J., Freischütz, B., Yu, R. K., Nonneman, D., Johnson, G. S., Boon, G. D., Stogsdill, P. L. & Ledoux, D. R., Jan 1 1997, In : Avian Diseases. 41, 4, p. 838-849 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Promoter for rat CMP-NTUAC: Gm3 a2.8 sialyltransfkrase gene

Yu, R. K., Gao, L. & Zeng, G., Dec 1 1997, In : FASEB Journal. 11, 9

Research output: Contribution to journalArticle

Unusual gangliosidosis in emu (Dromaius novaehollandiae)

Freischütz, B., Tokuda, A., Ariga, T., Bermudez, A. J. & Yu, R. K., May 1997, In : Journal of Neurochemistry. 68, 5, p. 2070-2078 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
1996

Association of a 14-3-3 protein with CMP-NeuAc:GM1 α2,3-Sialyltransferase

Gao, L., Gu, X. B., Yu, D. S., Yu, R. K. & Zeng, G., Jul 5 1996, In : Biochemical and Biophysical Research Communications. 224, 1, p. 103-107 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Expression and localization of Lewisx glycolipids and GD1a ganglioside in human glioma cells

Ariga, T., Bhat, S., Kanda, T., Yamawaki, M., Tai, T., Kushi, Y., Kasama, T., Handa, S. & Yu, R. K., Jan 1 1996, In : Glycoconjugate Journal. 13, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Expression of a unique globo-series glycolipid in cultured rat dorsal root ganglion neurons: Relationship with neuronal development

Pal, S., Bigbee, J. W., Saito, M., Ariga, T. & Yu, R. K., Apr 1996, In : Neurochemical Research. 21, 4, p. 403-409 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Generation and characterization of anti-sulfoglucuronosyl paragloboside monoclonal antibody NGR50 and its immunoreactivity with peripheral nerve

Yamawaki, M., Ariga, T., Bigbee, J. W., Ozawa, H., Kawashima, I., Tai, T., Kanda, T. & Yu, R. K., Jun 15 1996, In : Journal of Neuroscience Research. 44, 6, p. 586-593 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Molecular cloning of cDNA for rat brain GD3-synthase

Zeng, G., Gao, L., Ariga, T. & Yu, R. K., Sep 13 1996, In : Biochemical and Biophysical Research Communications. 226, 2, p. 319-323 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Neuritogenesis, Not Receptor Expression, of NG108-15 Cells Can be Modulated by Monosialoganglioside GM1

Hwang, H. M., Weng, S. C., Lo, S. K., Yu, R. K. & Tsai, W. H., Jan 1 1996, In : Chinese Journal of Physiology. 39, 4, p. 211-217 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Sensitization of Lewis rats with sulfoglucuronosyl paragloboside: Electrophysiological and immunological studies of an animal model of peripheral neuropathy

Yamawaki, M., Vasquez, A., Younes, A. B., Yoshino, H., Kanda, T., Ariga, T., Baumann, N. & Yu, R. K., Apr 22 1996, In : Journal of Neuroscience Research. 44, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Sialidase activity in nuclear membranes of rat brain

Saito, M., Fronda, C. L. & Yu, R. K., May 1996, In : Journal of Neurochemistry. 66, 5, p. 2205-2208 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Transcriptional activation of the interleukin-8 gene by respiratory syncytial virus infection in alveolar epithelial cells: Nuclear translocation of the RelA transcription factor as a mechanism producing airway mucosal inflammation

Garofalo, R., Sabry, M., Jamaluddin, M., Yu, R. K., Casola, A., Ogra, P. L. & Brasier, A. R., Dec 1996, In : Journal of Virology. 70, 12, p. 8773-8781 9 p.

Research output: Contribution to journalArticle

Open Access
176 Scopus citations
1995

Accumulation of isogloboside and ganglio-N-tetraosyl ceramide having blood group B determinant in the hepatomas of female LEC rats

Ariga, T., Kasai, N., Miyoshi, I., Yamawaki, M., Scarsdale, J. N., Yu, R. K., Kasama, T. & Taki, T., Feb 9 1995, In : Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. 1254, 3, p. 257-266 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Analysis of the antibody response to immunization with purified O‐acetyl GD3 gangliosides in patients with malignant melanoma

Ritter, G., Ritter‐Boosfeld, E., Adluri, R., Calves, M., Ren, S., Yu, R. K., Oettgen, H. F., Old, L. J. & Livingston, P. O., Sep 15 1995, In : International Journal of Cancer. 62, 6, p. 668-672 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Anti-sulfoglucuronyl paragloboside IgM antibodies in amyotrophic lateral sclerosis

Younes-Chennoufi, A. B., Rozier, A., Dib, M., Bouche, P., Lacomblez, L., Mombo, N., Simon, G. B., Yu, R. K., Baumann, N. & Meininger, V., Mar 1995, In : Journal of Neuroimmunology. 57, 1-2, p. 111-115 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Characterization of sialidase activity in mouse synaptic plasma membranes and its age‐related changes

Saito, M., Tanaka, Y., Tang, C. P., Yu, R. K. & Ando, S., Feb 15 1995, In : Journal of Neuroscience Research. 40, 3, p. 401-406 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Characterization of Sialyltransferase‐IV Activity and Its Involvement in the c‐Pathway of Brain Ganglioside Metabolism

Freischütz, B., Saito, M., Rahmann, H. & Yu, R. K., Jan 1995, In : Journal of Neurochemistry. 64, 1, p. 385-393 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effect of Nerve Growth Factor and Forskolin on Glycosyltransferase Activities and Expression of a Globo‐Series Glycosphingolipid in PC12D Pheochromocytoma Cells

Kanda, T., Ariga, T., Yamawaki, M., Pal, S., Katoh‐Semba, R. & Yu, R. K., Feb 1995, In : Journal of Neurochemistry. 64, 2, p. 810-817 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Glycosphingolipid Composition of Murine Neuroblastoma Cells: O-Acetylesterase Gene Downregulates the Expression of O-Acetylated GD3

Ariga, T., Blaine, G. M., Yoshino, H., Dawson, G., Kanda, T., Zeng, G. C., Kasama, T., Kushi, Y. & Yu, R. K., Sep 1995, In : Biochemistry. 34, 36, p. 11500-11507 8 p.

Research output: Contribution to journalArticle

33 Scopus citations
41 Scopus citations
52 Scopus citations

Regulation of Sialyltransferase Activities by Phosphorylation and Dephosphorylation

Gu, X., Preuß, U., Gu, T. & Yu, R. K., May 1995, In : Journal of Neurochemistry. 64, 5, p. 2295-2302 8 p.

Research output: Contribution to journalArticle

41 Scopus citations
1994

Activities of Five Different Sialyltransferases in Fish and Rat Brains

Freischütz, B., Saito, M., Rahmann, H. & Yu, R. K., May 1994, In : Journal of Neurochemistry. 62, 5, p. 1965-1973 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Biosynthesis of glycosphingolipids is reduced in the absence of a vimentin intermediate filament network

Gillard, B. K., Thurmon, L. T., Harrell, R. G., Capetanaki, Y., Saito, M., Yu, R. K. & Marcus, D. M., 1994, In : Journal of Cell Science. 107, 12, p. 3545-3555 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Development regulation of ganglioside metabolism

Yu, R. K., Jan 1 1994, In : Progress in Brain Research. 101, C, p. 31-44 14 p.

Research output: Contribution to journalArticle

145 Scopus citations

Differential effects of glycosphingolipids on protein kinase C activity in PC12D pheochromocytoma cells

Yu, R. K., Ariga, T., Yoshino, H., Katoh-Semba, R. & Ren, S., Oct 1 1994, In : Journal of Biomedical Science. 1, 4, p. 229-236 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Endogenous Phosphorylation of a 61,000 Dalton Hippocampal Protein Increases Following Traumatic Brain Injury

Yang, K., Taft, W. C., Dixon, C. E., yu, R. K. & Hayes, R. L., Oct 1994, In : Journal of Neurotrauma. 11, 5, p. 523-532 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

GD3 Vaccines for Melanoma: Superior Immunogenicity of Keyhole Limpet Hemocyanin Conjugate Vaccines

Helling, F., Shang, A., Calves, M., Zhang, S., Ren, S., Yu, R. K., Oettgen, H. F. & Livingston, P. O., Jan 1994, In : Cancer Research. 54, 1, p. 197-203 7 p.

Research output: Contribution to journalArticle

177 Scopus citations

Glycolipid composition of human cataractous lenses. Characterization of Lewis glycolipids

Ariga, T., Tao, R. V., Lee, B. C., Yamawaki, M., Yoshino, H., Scarsdale, N. J., Kasama, T., Kushi, Y. & Yu, R. K., 1994, In : Journal of Biological Chemistry. 269, 4, p. 2667-2675 9 p.

Research output: Contribution to journalArticle

27 Scopus citations