• 15996 Citations
  • 61 h-Index
1963 …2021

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Article
1994

Glycosphingolipid antigens in cultured microvascular bovine brain endothelial cells: Sulfoglucuronosyl paragloboside as a target of monoclonal IgM in demyelinative neuropathy

Kanda, T., Yoshino, H., Ariga, T., Yamawaki, M. & Yu, R. K., 1994, In : Journal of Cell Biology. 126, 1, p. 235-246 12 p.

Research output: Contribution to journalArticle

65 Scopus citations

Inhibition of LPS-mediated cell activation in vitro and in vivo by gangliosides

Mond, J. J., Witherspoon, K., Yu, R. K., Perera, P. Y. & Vogel, S. N., Dec 1 1994, In : Circulatory Shock. 44, 2, p. 57-62 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Modification of sialic acids by 9-O-acetylation is detected in human leucocytes using the lectin property of influenza C virus

Zimmer, G., Suguri, T., Reuter, G., Yu, R. K., Schauer, R. & Herrler, G., Jun 1994, In : Glycobiology. 4, 3, p. 343-349 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
45 Scopus citations

Modulation of phospholipases a2 and c activities against dilauroylphosphorylcholine in mixed monolayers with semisynthetic derivatives of ganglioside and sphingosine

Perillo, M. A., Guidotti, A., Costa, E., Yu, R. K. & Maggio, B., Jan 1 1994, In : Molecular Membrane Biology. 11, 2, p. 119-126 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Modulation of the activity of Clostridium perfringens neuraminidase by the molecular organization of gangliosides in monolayers

Perillo, M. A., Yu, R. K. & Maggio, B., Jul 13 1994, In : BBA - Biomembranes. 1193, 1, p. 155-164 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Oligodendroglial cyclic AMP response element‐binding protein: A member of the CREB family of transcription factors

Sato‐Bigbee, C., Chan, E. L. P. & Yu, R. K., Aug 15 1994, In : Journal of Neuroscience Research. 38, 6, p. 621-628 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Regulation by gangliosides and sulfatides of phospholipase A2 activity against dipalmitoyl- and dilauroylphosphatidylcholine in small unilamellar bilayer vesicles and mixed monolayers

Maggio, B., Bianco, I. D., Montich, G. G., Fidelio, G. D. & Yu, R. K., Feb 23 1994, In : BBA - Biomembranes. 1190, 1, p. 137-148 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Subcellular distribution of sulfated glucuronyl glycolipids in human peripheral motor and sensory nerves

Yu, R. K., Yoshino, H., Yamawaki, M., Yoshino, J. E. & Ariga, T., Jun 1 1994, In : Journal of Biomedical Science. 1, 3, p. 167-171 5 p.

Research output: Contribution to journalArticle

23 Scopus citations
1995

Accumulation of isogloboside and ganglio-N-tetraosyl ceramide having blood group B determinant in the hepatomas of female LEC rats

Ariga, T., Kasai, N., Miyoshi, I., Yamawaki, M., Scarsdale, J. N., Yu, R. K., Kasama, T. & Taki, T., Feb 9 1995, In : Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. 1254, 3, p. 257-266 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Analysis of the antibody response to immunization with purified O‐acetyl GD3 gangliosides in patients with malignant melanoma

Ritter, G., Ritter‐Boosfeld, E., Adluri, R., Calves, M., Ren, S., Yu, R. K., Oettgen, H. F., Old, L. J. & Livingston, P. O., Sep 15 1995, In : International Journal of Cancer. 62, 6, p. 668-672 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Anti-sulfoglucuronyl paragloboside IgM antibodies in amyotrophic lateral sclerosis

Younes-Chennoufi, A. B., Rozier, A., Dib, M., Bouche, P., Lacomblez, L., Mombo, N., Simon, G. B., Yu, R. K., Baumann, N. & Meininger, V., Mar 1995, In : Journal of Neuroimmunology. 57, 1-2, p. 111-115 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Characterization of sialidase activity in mouse synaptic plasma membranes and its age‐related changes

Saito, M., Tanaka, Y., Tang, C. P., Yu, R. K. & Ando, S., Feb 15 1995, In : Journal of Neuroscience Research. 40, 3, p. 401-406 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Characterization of Sialyltransferase‐IV Activity and Its Involvement in the c‐Pathway of Brain Ganglioside Metabolism

Freischütz, B., Saito, M., Rahmann, H. & Yu, R. K., Jan 1 1995, In : Journal of Neurochemistry. 64, 1, p. 385-393 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effect of Nerve Growth Factor and Forskolin on Glycosyltransferase Activities and Expression of a Globo‐Series Glycosphingolipid in PC12D Pheochromocytoma Cells

Kanda, T., Ariga, T., Yamawaki, M., Pal, S., Katoh‐Semba, R. & Yu, R. K., Feb 1995, In : Journal of Neurochemistry. 64, 2, p. 810-817 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Glycosphingolipid Composition of Murine Neuroblastoma Cells: O-Acetylesterase Gene Downregulates the Expression of O-Acetylated GD3

Ariga, T., Blaine, G. M., Yoshino, H., Dawson, G., Kanda, T., Zeng, G. C., Kasama, T., Kushi, Y. & Yu, R. K., Sep 1995, In : Biochemistry. 34, 36, p. 11500-11507 8 p.

Research output: Contribution to journalArticle

33 Scopus citations
41 Scopus citations
52 Scopus citations

Regulation of Sialyltransferase Activities by Phosphorylation and Dephosphorylation

Gu, X., Preuß, U., Gu, T. & Yu, R. K., May 1995, In : Journal of Neurochemistry. 64, 5, p. 2295-2302 8 p.

Research output: Contribution to journalArticle

41 Scopus citations
1996

Association of a 14-3-3 protein with CMP-NeuAc:GM1 α2,3-Sialyltransferase

Gao, L., Gu, X. B., Yu, D. S., Yu, R. K. & Zeng, G., Jul 5 1996, In : Biochemical and Biophysical Research Communications. 224, 1, p. 103-107 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Expression and localization of Lewisx glycolipids and GD1a ganglioside in human glioma cells

Ariga, T., Bhat, S., Kanda, T., Yamawaki, M., Tai, T., Kushi, Y., Kasama, T., Handa, S. & Yu, R. K., Jan 1 1996, In : Glycoconjugate Journal. 13, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Expression of a unique globo-series glycolipid in cultured rat dorsal root ganglion neurons: Relationship with neuronal development

Pal, S., Bigbee, J. W., Saito, M., Ariga, T. & Yu, R. K., Apr 1 1996, In : Neurochemical Research. 21, 4, p. 403-409 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Generation and characterization of anti-sulfoglucuronosyl paragloboside monoclonal antibody NGR50 and its immunoreactivity with peripheral nerve

Yamawaki, M., Ariga, T., Bigbee, J. W., Ozawa, H., Kawashima, I., Tai, T., Kanda, T. & Yu, R. K., Jun 15 1996, In : Journal of Neuroscience Research. 44, 6, p. 586-593 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Molecular cloning of cDNA for rat brain GD3-synthase

Zeng, G., Gao, L., Ariga, T. & Yu, R. K., Sep 13 1996, In : Biochemical and Biophysical Research Communications. 226, 2, p. 319-323 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Neuritogenesis, Not Receptor Expression, of NG108-15 Cells Can be Modulated by Monosialoganglioside GM1

Hwang, H. M., Weng, S. C., Lo, S. K., Yu, R. K. & Tsai, W. H., Jan 1 1996, In : Chinese Journal of Physiology. 39, 4, p. 211-217 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Sensitization of Lewis rats with sulfoglucuronosyl paragloboside: Electrophysiological and immunological studies of an animal model of peripheral neuropathy

Yamawaki, M., Vasquez, A., Younes, A. B., Yoshino, H., Kanda, T., Ariga, T., Baumann, N. & Yu, R. K., Apr 22 1996, In : Journal of Neuroscience Research. 44, 1, p. 58-65 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Sialidase activity in nuclear membranes of rat brain

Saito, M., Fronda, C. L. & Yu, R. K., May 1996, In : Journal of Neurochemistry. 66, 5, p. 2205-2208 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Transcriptional activation of the interleukin-8 gene by respiratory syncytial virus infection in alveolar epithelial cells: Nuclear translocation of the RelA transcription factor as a mechanism producing airway mucosal inflammation

Garofalo, R., Sabry, M., Jamaluddin, M., Yu, R. K., Casola, A., Ogra, P. L. & Brasier, A. R., Dec 1996, In : Journal of Virology. 70, 12, p. 8773-8781 9 p.

Research output: Contribution to journalArticle

Open Access
176 Scopus citations
1997

Antibodies to glycosphingolipid antigens in patients with immune-mediated cochleovestibular disorders

Lake, G. M., Sismanis, A., Ariga, T., Yamawaki, M., Gao, Y. & Yu, R. K., Mar 1 1997, In : American Journal of Otology. 18, 2, p. 175-178 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Cloning, characterization, and expression of human ceramide galactosyltransferase cDNA

Kapitonov, D. & Yu, R. K., Mar 17 1997, In : Biochemical and Biophysical Research Communications. 232, 2, p. 449-453 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cloning of the cDNA coding for rat brain CMP-NeuAc:GD3 α2-8 sialyltransferase

Zeng, G., Gao, L. & Yu, R. K., Mar 10 1997, In : Gene. 187, 1, p. 131-134 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Ganglioside GD3 and GD3-lactone mediated regulation of the intermolecular organization in mixed monolayers with dipalmitoylphosphatidylcholine

Maggio, B., Ariga, T., Calderón, R. O. & Yu, R. K., Nov 19 1997, In : Chemistry and Physics of Lipids. 90, 1-2, p. 1-10 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Glycosyltransferase activities in cultured endothelial cells of bovine brain microvascular origin

Kanda, T., Ariga, T., Yamawaki, M., Yoshino, H., Gu, X. B. & Yu, R. K., Jan 1 1997, In : Neurochemical Research. 22, 4, p. 463-466 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Heritability and biochemistry of gangliosidosis in emus (Dromaius novaehollandiae)

Bermudez, A. J., Freischütz, B., Yu, R. K., Nonneman, D., Johnson, G. S., Boon, G. D., Stogsdill, P. L. & Ledoux, D. R., Jan 1 1997, In : Avian Diseases. 41, 4, p. 838-849 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Promoter for rat CMP-NTUAC: Gm3 a2.8 sialyltransfkrase gene

Yu, R. K., Gao, L. & Zeng, G., Dec 1 1997, In : FASEB Journal. 11, 9

Research output: Contribution to journalArticle

Unusual gangliosidosis in emu (Dromaius novaehollandiae)

Freischütz, B., Tokuda, A., Ariga, T., Bermudez, A. J. & Yu, R. K., May 1997, In : Journal of Neurochemistry. 68, 5, p. 2070-2078 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
1998

Antiglycolipid antibodies in motor neuropathies

Baumann, N., Harpin, M. L., Marie, Y., Lemerle, K., Chassande, B., Bouche, P., Meininger, V., Yu, R. K. & Léger, J. M., 1998, In : Annals of the New York Academy of Sciences. 845, p. 322-329 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cloning of promoter for rat GD3-synthase gene

Gao, L., Zeng, G. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

Developmental expression of rat brain GD3-and GT3-synthases

Zeng, G., Gao, L., Freischütz, B., Tokuda, A. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

GM1 ganglioside inhibits amyloid β-protein induced-cytokine release

Ariga, T. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Heterogeneity of antibody specificity in Taiwanese patients with polyneuropathy and IgM paraproteinemia

Lin, K. P., Tsai, C. P., Yamawaki, M., Ariga, T. & Yu, R. K., Jan 1 1998, In : Journal of Biomedical Science. 5, 6, p. 441-445 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Isolation and functional analysis of the promoter of the rat CMP-NeuAc:GM3 α 2,8 sialyltransferase gene

Zeng, G., Gao, L. & Yu, R. K., Apr 27 1998, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1397, 2, p. 126-130 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

On the specificity of anti-sulfoglucuronosyl glycolipid antibodies

Tokuda, A., Ariga, T., Isogai, Y., Komba, S., Kiso, M., Hasegawa, A., Tai, T. & Yu, R. K., Jan 1 1998, In : Journal of Carbohydrate Chemistry. 17, 4-5, p. 535-546 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Permanent alteration of endogenous gangliosides in neuroblastoma cells by stable transfection with antisense vector

Zeng, G., Gao, L., Li, D. D., Tokuda, A. & Yu, R. K., Jan 1 1998, In : Annals of the New York Academy of Sciences. 845, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Regulation of ganglioside metabolism by phosphorylation and dephosphorylation

Bieberich, E., Freischütz, B., Liour, S. S. & Yu, R. K., Sep 1998, In : Journal of Neurochemistry. 71, 3, p. 972-979 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Sulfoglucuronosyl glycolipids as putative antigens for autoimmune inner ear disease

Yamawaki, M., Ariga, T., Gao, Y., Tokuda, A., Yu, J. S., Sismanis, A. & Yu, R. K., Apr 15 1998, In : Journal of Neuroimmunology. 84, 2, p. 111-116 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

The role of glycosphinglipids in neurological disorders - Mechanisms of immune action

Yu, R. K. & Ariga, T., 1998, In : Annals of the New York Academy of Sciences. 845, p. 285-306 22 p.

Research output: Contribution to journalArticle

35 Scopus citations
1999

Alteration of ganglioside composition by stable transfection with antisense vectors against GD3-synthase gene expression

Zeng, G., Li, D. D., Gao, L., Birklé, S., Bieberich, E., Tokuda, A. & Yu, R. K., Jul 6 1999, In : Biochemistry. 38, 27, p. 8762-8769 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Combinatorial PCR approach to homology-based cloning: Cloning and expression of mouse and human GM3-synthase

Kapitonov, D., Bieberich, E. & Yu, R. K., Nov 25 1999, In : Glycoconjugate Journal. 16, 7, p. 337-350 14 p.

Research output: Contribution to journalArticle

35 Scopus citations

Conserved domains of glycosyltransferases

Kapitonov, D. & Yu, R. K., Oct 1999, In : Glycobiology. 9, 10, p. 961-978 18 p.

Research output: Contribution to journalArticle

134 Scopus citations