Robert William Caldwell

Professor - Rehired Retiree

  • 6429 Citations
  • 46 h-Index
1970 …2020

Research output per year

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Research Output

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Comparison of the therapeutic index (TI) of aminosugar cardiac glycosides with digoxin (D)

Caldwell, R. W. & Nash, C. B., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No.3705

Research output: Contribution to journalArticle

1 Scopus citations

Contraction-induced cell wounding and release of fibroblast growth factor in heart

Clarke, M. S. F., Caldwell, R. W., Chiao, H., Miyake, K. & McNeil, P. L., Jan 1 1995, In : Circulation Research. 76, 6, p. 927-934 8 p.

Research output: Contribution to journalArticle

165 Scopus citations

Cytokine profiling of young overweight and obese female African American adults with prediabetes

Lucas, R., Parikh, S. J., Sridhar, S., Guo, D. H., Bhagatwala, J., Dong, Y., Caldwell, R., Mellor, A., Caldwell, W., Zhu, H. & Dong, Y., Oct 2013, In : Cytokine. 64, 1, p. 310-315 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model

Bhatta, A., Sangani, R., Kolhe, R., Toque, H. A., Cain, M., Wong, A., Howie, N., Shinde, R., Elsalanty, M., Yao, L., Chutkan, N., Hunter, M., Caldwell, R. B., Isales, C., Caldwell, R. W. & Fulzele, S., Feb 15 2016, In : Molecular and Cellular Endocrinology. 422, p. 211-220 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Diabetes-induced coronary vascular dysfunction involves increased arginase activity

Romero, M. J., Platt, D. H., Tawfik, H. E., Labazi, M., El-Remessy, A. B., Bartoli, M., Caldwell, R. B. & Caldwell, R. W., Jan 2008, In : Circulation research. 102, 1, p. 95-102 8 p.

Research output: Contribution to journalArticle

264 Scopus citations

Diabetes-induced vascular dysfunction involves arginase

Romero, M. J., Iddings, J. A., Platt, D. H., Irfan Ali, M., Cederbaum, S. D., Stepp, D. W., Caldwell, R. B. & Caldwell, R. W., Jan 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 302, 1, p. H159-H166

Research output: Contribution to journalArticle

61 Scopus citations
29 Scopus citations

Different patterns of autonomic nerve activity produced by a polar vs. a neutral cardiac glycoside

Rebagay, W. R. & Caldwell, R. W., Jan 1 1990, In : Journal of Pharmacology and Experimental Therapeutics. 253, 1, p. 180-184 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Digoxin uptake into peripheral autonomic cardiac nerves: Possible mechanism of digitalis-induced antiarrhythmic and toxic electrophysiologic actions

Cook, L. S., Doherty, J. E., Straub, K. D., Nash, C. B. & Caldwell, R. W., Jul 1981, In : American Heart Journal. 102, 1, p. 58-62 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Downregulation of nitrovasodilator-induced cyclic GMP accumulation in cells exposed to endotoxin or interleukin-1β

Papapetropoulos, A., Abou-Mohamed, G., Marczin, N., Murad, F., Caldwell, R. W. & Catravas, J. D., 1996, In : British Journal of Pharmacology. 118, 6, p. 1359-1366 8 p.

Research output: Contribution to journalArticle

78 Scopus citations

Effect of an aminocardenolide and digoxin upon atrioventricular refractory period in the dog

Caldwell, R. W. & Nash, C. B., Dec 1 1985, In : Journal of Pharmacology and Experimental Therapeutics. 235, 3, p. 583-588 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effect of Anteroventral Third Ventricle Lesions on Vascular Sodium-Pump Activity in Two-Kidney Goldblatt Hypertension

Songu-Mize, E., Bealer, S. L. & Caldwell, R. W., 1983, In : Hypertension. 5, 2, p. I-89-I-93

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Effect of a polar cardenolide and digoxin upon A-V refractory period

Caldwell, R. W. & Nash, C. B., Jan 1 1982, In : Federation Proceedings. 41, 5, p. No. 8431

Research output: Contribution to journalArticle

Effect of AV3V lesions on development of DOCA-Salt hypertension and vascular Na+-pump activity

Songu-Mize, E., Bealer, S. L. & Caldwell, R. W., 1982, In : Hypertension. 4, 5, p. 575-580 6 p.

Research output: Contribution to journalArticle

120 Scopus citations

Effect of cardiac β-adrenergic blockade or denervation on cardiotoxicity of digoxin and an aminosugar cardenolide

Puryear, S. K., Nash, C. B. & Caldwell, R. W., Jan 1 1981, In : Journal of Cardiovascular Pharmacology. 3, 1, p. 113-127 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
12 Scopus citations

Effect of diterpenoid alkaloids on cardiac sympathetic efferent and vagal afferent nerve activity

Chiao, H., Pelletier, S. W., Desai, H. K., Rebagay, W. R. & Caldwell, R. W., Sep 5 1995, In : European Journal of Pharmacology. 283, 1-3, p. 103-106 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

Effect of DOCA-salt treatment duration and anteroventral third ventricle lesions on a plasma-borne sodium pump inhibitor in rats

Songu-Mize, E., Bealer, S. L. & Caldwell, R. W., Aug 1987, In : Journal of hypertension. 5, 4, p. 461-467 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Effect of DOCA-salt treatment duration on a plasma-borne sodium pump inhibitor

Songu-Mize, E., Bealer, S. L. & Caldwell, R. W., Jan 1 1985, In : Federation Proceedings. 44, 5

Research output: Contribution to journalArticle

Effect of halothane on in vivo and in vitro cardiotoxicity of an aminocardenolide

Heerdt, P. M., Gallagher, J. D. & Caldwell, R. W., Jun 1994, In : Journal of Cardiovascular Pharmacology. 23, 6, p. 890-896 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effect of lesions of the nucleus tractus solitarii on the cardiovascular actions of clonidine in conscious rats

Rockhold, R. W. & Caldwell, R. W., Apr 1979, In : Neuropharmacology. 18, 4, p. 347-354 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells

Banes-Berceli, A. K., Shaw, S., Ma, G., Brands, M., Eaton, D. C., Stern, D. M., Fulton, D., Caldwell, R. W. & Marrero, M. B., Jun 30 2006, In : American Journal of Physiology - Renal Physiology. 291, 1, p. F116-F121

Research output: Contribution to journalArticle

49 Scopus citations

Effect of sympathectomy and vagotomy on the cardiotoxicity of an aminosugar cardiac glycoside

Puryear, S. K., Nash, C. B. & Caldwell, R. W., Jan 1 1979, In : Federation Proceedings. 38, 3 I

Research output: Contribution to journalArticle

Effect of transient vagal cold blockade upon reflex actions of a polar and nonpolar cardiac glycoside

Caldwell, R. W. & Rebagay, W. R., Jan 1 1992, In : Journal of Pharmacology and Experimental Therapeutics. 262, 3, p. 1022-1027 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of aminosugar substitution on cardiac glycoside responses in the heart lung preparation

Cook, L. S., Caldwell, R. W. & Nash, C. B., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No.3704

Research output: Contribution to journalArticle

Effects of NO donors and synthase agonists on endothelial cell uptake of L-Arg and superoxide production

Ogonowski, A. A., Kaesemeyer, W. H., Jin, L., Ganapathy, V., Leibach, F. H. & Caldwell, R. W., Jan 1 2000, In : American Journal of Physiology - Cell Physiology. 278, 1 47-1, p. C136-C143

Research output: Contribution to journalArticle

61 Scopus citations

Effects of sinoaortic denervation on the reflex actions of digoxin and a polar aminocardenolide

Rebagay, W. R. & Caldwell, R. W., Jan 1992, In : Journal of Cardiovascular Pharmacology. 19, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Elastic fibers in the annulus fibrosus of the dog intervertebral disc

Johnson, E. F., Caldwell, R. W. & Berryman, H. E., Jan 1 1984, In : Acta Anatomica. 118, 4, p. 238-242 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Elastic fibers in the anulus fibrosus of the dog intervertebral disc

Johnson, E. F., Caldwell, R. W., Berryman, H. E., Miller, A. & Chetty, K., Jan 1 1984, In : Cells Tissues Organs. 118, 4, p. 238-242 5 p.

Research output: Contribution to journalArticle

Electropharmacological effect of aminosugar substitution on digitoxigenin

Cook, L. S., Caldwell, R. W. & Nash, C. B., Jan 1 1978, In : Federation Proceedings. 37, 3, p. No. 3685

Research output: Contribution to journalArticle

Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma

Ha, Y., Liu, H., Xu, Z., Yokota, H., Narayanan, S. P., Lemtalsi, T., Smith, S. B., Caldwell, R. W., Caldwell, R. B. & Zhang, W., Oct 1 2015, In : Cell Death and Disease. 6, 10, e1900.

Research output: Contribution to journalArticle

28 Scopus citations

Endothelial cell dysfunction in a model of oxidative stress

Jin, L., Abou-Mohamed, G., Caldwell, R. B. & Caldwell, R. W., Aug 9 2001, In : Medical Science Monitor. 7, 4, p. 585-591 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Endothelial nitric oxide synthase is a site of superoxide synthesis in endothelial cells treated with glyceryl trinitrate

Kaesemeyer, W. H., Ogonowski, A. A., Jin, L., Caldwell, R. B. & Caldwell, R. W., 2000, In : British Journal of Pharmacology. 131, 5, p. 1019-1023 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

Estradiol relaxes rat aorta via endothelium-dependent and -independent mechanisms

Abou-Mohamed, G., Elmarakby, A., Carrier, G. O., Catravas, J. D., Caldwell, R. W. & White, R. E., Aug 11 2003, In : Pharmacology. 69, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
172 Scopus citations
17 Scopus citations

Halothane anesthesia and angiotensin I conversion in the dog

Heerdt, P. M., Nash, C. B. & Caldwell, R. W., Jan 1 1981, In : Clinical Research. 29, 4

Research output: Contribution to journalArticle

High and Low Dietary Potassium Effects on Rat Vascular Sodium Pump Activity

Songu-Mize, E., Caldwell, R. W. & Baer, P. G., Dec 1987, In : Proceedings of the Society for Experimental Biology and Medicine. 186, 3, p. 280-287 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

High glucose-induced tyrosine nitration in endothelial cells: Role of eNOS uncoupling and aldose reductase activation

El-Remessy, A. B., Abou-Mohamed, G., Caldwell, R. W. & Caldwell, R. B., Jul 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 7, p. 3135-3143 9 p.

Research output: Contribution to journalArticle

106 Scopus citations

High glucose upregulates arginase 1 and decreases nitric oxide production through ATF-2 and c-Jun transcription factors

Shatanawi, A., Gharaibeh, M. N., Caldwell, R. B. & Caldwell, R. W., Jan 1 2014, In : Life Science Journal. 11, 5, p. 374-379 6 p., 50.

Research output: Contribution to journalArticle

5 Scopus citations

HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy

Bartoli, M., Al-Shabrawey, M., Labazi, M., Ali Behzadian, M., Istanboli, M., El-Remessy, A. B., Caldwell, R. W., Marcus, D. M. & Caldwell, R. B., Dec 1 2009, In : Investigative Ophthalmology and Visual Science. 50, 10, p. 4934-4940 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Homocysteine induces endothelial dysfunction via inhibition of arginine transport

Jin, L., Caldwell, R. B., Li-Masters, T. & Caldwell, R. W., Jun 1 2007, In : Journal of Physiology and Pharmacology. 58, 2, p. 191-206 16 p.

Research output: Contribution to journalArticle

64 Scopus citations

HP-228, a novel synthetic peptide, inhibits the induction of nitric oxide synthase in vivo but not in vitro

Abou-Mohamed, G., Papapetropoulos, A., Ulrich, D., Catravas, J. D., Tuttle, R. R. & Caldwell, R. W., Dec 1 1995, In : Journal of Pharmacology and Experimental Therapeutics. 275, 2, p. 584-591 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2

Tawfik, A. M., Jin, L., Banes-Berceli, A. K. L., Caldwell, R. B., Ogbi, S., Shirley, A., Barber, D., Catravas, J. D., Stern, D. M., Fulton, D. J., Caldwell, R. W. & Marrero, M. B., Nov 1 2005, In : Vascular Pharmacology. 43, 5, p. 320-326 7 p.

Research output: Contribution to journalArticle

28 Scopus citations
7 Scopus citations

Hyperoxia causes regression of vitreous neovascularization by downregulating VEGF/VEGFR2 pathway

Liu, H., Zhang, W., Xu, Z., Caldwell, R. W., Caldwell, R. B. & Brooks, S. E., Feb 2013, In : Investigative Ophthalmology and Visual Science. 54, 2, p. 918-931 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Hyperoxia therapy of pre-proliferative ischemic retinopathy in a mouse model

Zhang, W., Yokota, H., Xu, Z., Narayanan, S. P., Yancey, L., Yoshida, A., Marcus, D. M., Caldwell, R. W., Caldwell, R. B. & Brooks, S. E., Aug 2011, In : Investigative Ophthalmology and Visual Science. 52, 9, p. 6384-6395 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice

Anea, C. B., Cheng, B., Sharma, S., Kumar, S., Caldwell, R. W., Yao, L., Ali, M. I., Merloiu, A. M., Stepp, D. W., Black, S. M., Fulton, D. J. R. & Rudic, R. D., Oct 12 2012, In : Circulation research. 111, 9, p. 1157-1165 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy

Al-Shabrawey, M., Bartoli, M., El-Remessy, A. B., Platt, D. H., Matragoon, S., Behzadian, M. A., Caldwell, R. W. & Caldwell, R. B., Aug 2005, In : American Journal of Pathology. 167, 2, p. 599-607 9 p.

Research output: Contribution to journalArticle

159 Scopus citations