Robert William Caldwell

Professor - Rehired Retiree

  • 6343 Citations
  • 44 h-Index
1970 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article

In situ localization of cholesterol in skeletal muscle by use of a monoclonal antibody

Clarke, M. S. F., Vanderburg, C. R., Bamman, M. M., Caldwell, R. W. & Feeback, D. L., 2000, In : Journal of Applied Physiology. 89, 2, p. 731-741 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Integrative cardiovascular actions of a novel catecholamine, GP-2-128

Abou-Mohamed, G., Caldwell, R. W., Ibrahim, T. M. & Tuttle, R. R., Jan 1 1994, In : Journal of Cardiovascular Pharmacology. 23, 3, p. 485-491 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Interactions of a novel catecholamine, GP-2-128, with adrenoceptors

Abou-Mohamed, G., Caldwell, R. W., Carrier, G. O., Elmazar, M. M. & Tuttie, R. R., Jan 1 1994, In : Journal of Cardiovascular Pharmacology. 23, 3, p. 492-500 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Interactions of pyridostigmine with cardiopulmonary systems and their relationships to plasma cholinesterase activity

Caldwell, R. W., Lowensohn, H. S., Chryssanthis, M. A. & Nash, C. B., Apr 1 1989, In : Toxicological Sciences. 12, 3, p. 432-441 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

L-arginjne in the development and reversal of tolerance to nitroglycerin

Abou-Molmmed, G., Suarez, A., Kaesemever, W. H., Panapetroooulos, A., Catravas, J. D. & Caldwell, R. W., Dec 1 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

2 Scopus citations

L-citrulline protects from kidney damage in type 1 diabetic mice

Romero Lucas, M. J., Yao, L., Sridhar, S., Bhatta, A., Dou, H., Ramesh, G., Brands, M. W., Pollock, D. M., Caldwell, R. B., Cederbaum, S. D., Alvin Head, C., Bagi, Z., Lucas, R. & Caldwell, R. W., Dec 1 2013, In : Frontiers in immunology. 4, DEC, Article 480.

Research output: Contribution to journalArticle

18 Scopus citations

Local cardiac effects of substance P: roles of acetylcholine and noradrenaline

Chiao, H. & Caldwell, R. W., Jan 1995, In : British Journal of Pharmacology. 114, 2, p. 283-288 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Localization and characterization of action of clonidine in nucleus tractus solitarii (NTS)

Rockhold, R. W. & Caldwell, R. W., Jan 1 1978, In : Federation Proceedings. 37, 3, p. No. 757

Research output: Contribution to journalArticle

Mechanism of the pulmonary vasoconstrictor action of digoxin

Mecca, T. E., Elam, J. T., Nash, C. B. & Caldwell, R. W., Jan 1 1981, In : Federation Proceedings. 40, 3 I, 1 p.

Research output: Contribution to journalArticle

Mechanism of the pulmonary vasoconstrictor action of digoxin in the dog

Mecca, T. E., Elam, J. T. & Caldwell, R. W., Jan 1 1985, In : Journal of Cardiovascular Pharmacology. 7, 5, p. 833-840 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Mechanisms of altered sodium excretion after preoptic hypothalamic lesions

Bealer, S. L., Caldwell, R. W. & Songu-Mize, E., Jan 1 1988, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 254, 1, p. 23/1

Research output: Contribution to journalArticle

12 Scopus citations

Mechanisms of diabetes-induced endothelial cell senescence: Role of arginase 1

Shosha, E., Xu, Z., Priya Narayanan, S., Lemtalsi, T., Fouda, A. Y., Rojas, M., Xing, J., Fulton, D., William Caldwell, R. & Caldwell, R. B., Apr 17 2018, In : International journal of molecular sciences. 19, 4, 1215.

Research output: Contribution to journalArticle

5 Scopus citations

Mechanisms of obesity-induced metabolic and vascular dysfunctions

Atawia, R. T., Bunch, K. L., Toque, H. A., Caldwell, R. B. & Caldwell, R. W., Mar 1 2019, In : Frontiers in Bioscience - Landmark. 24, 5, p. 890-934 45 p.

Research output: Contribution to journalArticle

7 Scopus citations

Metabolism and cardiac actions of a polar aminocardenolide and digoxin in the conscious dog

Songu Mize, E., Nash, C. B., Elam, J. T. & Caldwell, R. W., Jan 1 1983, In : Journal of Pharmacology and Experimental Therapeutics. 226, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock

Subramani, K., Lu, S., Warren, M., Chu, X., Flores Toque, H. A., Caldwell, R. W., Diamond, M. P. & Raju, R. P., Dec 1 2017, In : Scientific reports. 7, 1, 2653.

Research output: Contribution to journalArticle

8 Scopus citations

Modification of endotoxin shock with 1,18 diamino 6,13 diaza 9,10 dithiaoctadecane (WR 149,024)

Caldwell, R. W., Vick, J. A. & Heiffer, M. H., Jan 1 1973, In : Federation Proceedings. 32, 3 (I), 1 p.

Research output: Contribution to journalArticle

Modulation of digitalis induced contractile force responses by adrenergic and cholinergic mechanisms

Cook, L. S., Caldwell, R. W., Nash, C. B. & Doherty, J. E., Jan 1 1979, In : Clinical Research. 27, 5

Research output: Contribution to journalArticle

NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation

Zhang, W., Rojas, M., Lilly, B., Tsai, N. T., Lemtalsi, T., Liou, G. I., Caldwell, R. W. & Caldwell, R. B., 2009, In : Investigative Ophthalmology and Visual Science. 50, 6, p. 3033-3040 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Netrin-1 is a novel regulator of vascular endothelial function in diabetes

Toque, H. A., Fernandez-Flores, A., Mohamed, R., Caldwell, R. B., Ramesh, G. & Caldwell, R. W., Oct 2017, In : PloS one. 12, 10, e0186734.

Research output: Contribution to journalArticle

8 Scopus citations

Neuroprotection from retinal ischemia/reperfusion injury by NOX2 NADPH oxidase deletion

Yokota, H., Narayanan, S. P., Zhang, W., Liu, H., Rojas, M., Xu, Z., Lemtalsi, T., Nagaoka, T., Yoshida, A., Brooks, S. E., Caldwell, R. W. & Caldwell, R. B., Oct 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8123-8131 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Neuroprotective Effect of(-)Δ 9 -Tetrahydrocannabinol and Cannabidiol in N-Methyl-D-Aspartate-Induced Retinal Neurotoxicity: Involvement of Peroxynitrite

El-Remessy, A. B., Khalil, I. E., Matragoon, S., Abou-Mohamed, G., Tsai, N. J., Roon, P., Caldwell, R. B., Caldwell, R. W., Green, K. & Liou, G. I., Nov 2003, In : American Journal of Pathology. 163, 5, p. 1997-2008 12 p.

Research output: Contribution to journalArticle

164 Scopus citations

New approaches to the design and discovery of therapies to prevent erectile dysfunction

Toque, H. A. & Caldwell, R. W., Dec 1 2014, In : Expert Opinion on Drug Discovery. 9, 12, p. 1447-1469 23 p.

Research output: Contribution to journalArticle

9 Scopus citations

Nitrates supplemented with L-arginine for the reversal and treatment of nitrate tolerance: Two case reports

Kaesemeyer, W. H., Abou-Mohamed, G., Crute, T. D. & Caldwell, R. W., Dec 1 1996, In : Applied Cardiopulmonary Pathophysiology. 6, 4, p. 255-262 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Noninvasive delivery of a novel inotropic catecholamine: Iontophoretic versus intravenous infusion in dogs

Sanderson, J. E., Caldwell, R. W., Hsiao, J., Dixon, R. & Tuttle, R. R., Mar 1987, In : Journal of Pharmaceutical Sciences. 76, 3, p. 215-218 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Novel mechanisms of endothelial dysfunction in diabetes

Yang, G., Lucas, R., Caldwell, R., Yao, L., Romero, M. & Caldwell, R., Jan 1 2010, In : Journal of Cardiovascular Disease Research. 1, 2, p. 59-63 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1

Bhatta, A., Yao, L., Xu, Z., Toque, H. A., Chen, J., Atawia, R. T., Fouda, A. Y., Bagi, Z., Lucas, R., Caldwell, R. B. & Caldwell, R. W., Nov 1 2017, In : Cardiovascular Research. 113, 13, p. 1664-1676 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Obesity-induced vascular inflammation involves elevated arginase activity

Yao, L., Bhatta, A., Xu, Z., Chen, J., Toque, H. A., Chen, Y., Xu, Y., Bagi, Z., Lucas, R., Huo, Y., Caldwell, R. B. & Caldwell, R. W., Nov 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 313, 5, p. R560-R571

Research output: Contribution to journalArticle

11 Scopus citations

Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway

Chandra, S., Romero, M. J., Shatanawi, A., Alkilany, A. M., Caldwell, R. B. & Caldwell, R. W., Jan 1 2012, In : British Journal of Pharmacology. 165, 2, p. 506-519 14 p.

Research output: Contribution to journalArticle

101 Scopus citations

p38 Mitogen-Activated Protein Kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice

Toque, H. A., Romero, M. J., Tostes, R. C., Shatanawi, A., Chandra, S., Carneiro, Z. N., Inscho, E. W., Webb, R. C., Caldwell, R. B. & Caldwell, R. W., Dec 2010, In : Journal of Sexual Medicine. 7, 12, p. 3857-3867 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

Peroxynitrite mediates diabetes-induced endothelial dysfunction: possible role of Rho kinase activation.

El-Remessy, A. B., Tawfik, H. E., Matragoon, S., Pillai, B., Caldwell, R. B. & Caldwell, R. W., 2010, In : Experimental diabetes research. 2010, 1 p.

Research output: Contribution to journalArticle

Open Access
60 Scopus citations
2 Scopus citations

Pharmacological studies of a new 4 aminosugar cardiac glycoside (ASI 222)

Caldwell, R. W. & Nash, C. B., Dec 1 1976, In : Journal of Pharmacology and Experimental Therapeutics. 197, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Pharmacological studies of the therapy of shock

Vick, J. A., Heiffer, M. H., Caldwell, R. W., Neis, A. & Roberts, C. R., Jan 1 1973, In : Medicine (United States). 52, 4, p. 279-285 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Pharmacology of the enantiomers of threo-methylphenidate

Patrick, K. S., Caldwell, R. W., Ferris, R. M. & Breese, G. R., Jan 1 1987, In : Journal of Pharmacology and Experimental Therapeutics. 241, 1, p. 152-158 7 p.

Research output: Contribution to journalArticle

181 Scopus citations

Phasic vascular sodium pump changes in deoxycorticosterone-hypertensive rats

Songu-Mize, E., Bealer, S. L. & Caldwell, R. W., Jan 1 1984, In : Circulation research. 55, 3, p. 304-308 5 p.

Research output: Contribution to journalArticle

23 Scopus citations
334 Scopus citations

Pressor response induced by meta chlorotyrosine in cats

King, C. D. & Caldwell, R. W., Jan 1 1974, In : Pharmacologist. 16, 2, p. No. 511

Research output: Contribution to journalArticle

1 Scopus citations

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout

Yao, L., Chandra, S., Toque, H. A., Bhatta, A., Rojas, M., Caldwell, R. B. & Caldwell, R. W., Mar 1 2013, In : Cardiovascular Research. 97, 3, p. 509-519 11 p.

Research output: Contribution to journalArticle

61 Scopus citations
50 Scopus citations

Protective effects of the carotenoid zeaxanthin in experimental nonalcoholic steatohepatitis

Chamberlain, S. M., Hall, J. D., Patel, J., Lee, J. R., Marcus, D. M., Sridhar, S., Romero, M. J., Labazi, M., Caldwell, R. W. & Bartoli, M., Jul 1 2009, In : Digestive Diseases and Sciences. 54, 7, p. 1460-1464 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability

Lucas, R., Yang, G., Gorshkov, B. A., Zemskov, E. A., Sridhar, S., Siddaramappa, U. N., Jezierska-Drutel, A., Alieva, I. B., Leustik, M., Hossain, H., Fischer, B., Catravas, J. D., Verin, A. D., Pittet, J. F., Caldwell, R. B., Mitchell, T. J., Cederbaum, S. D., Fulton, D. J., Matthay, M. A., Caldwell, R. W. & 2 others, Romero Lucas, M. J. & Chakraborty, T., Oct 1 2012, In : American journal of respiratory cell and molecular biology. 47, 4, p. 445-453 9 p.

Research output: Contribution to journalArticle

34 Scopus citations
53 Scopus citations

Pulmonary and cardiovascular effects of mefloquine methanesulfonate

Caldwell, R. W. & Nash, C. B., Jun 1977, In : Toxicology and Applied Pharmacology. 40, 3, p. 437-448 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Regulation of MAP kinase-mediated endothelial dysfunction in hyperglycemia via arginase I and eNOS dysregulation

Mazrouei, S., Sharifpanah, F., Caldwell, R. W., Franz, M., Shatanawi, A., Muessig, J., Fritzenwanger, M., Schulze, P. C. & Jung, C., Sep 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 9, p. 1398-1411 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Renal tubular transport of a polar cardiac glycoside, ASI-222, in rats; Clearance and micropuncture studies

Kauker, M. L., Nash, C. B. & Caldwell, R. W., Jan 1 1981, In : Journal of Pharmacology and Experimental Therapeutics. 218, 3, p. 686-691 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Requirement of NOX2 expression in both retina and bone marrow for diabetes-induced retinal vascular injury

Rojas, M., Zhang, W., Xu, Z., Lemtalsi, T., Chandler, P., Toque, H. A., Caldwell, R. W. & Caldwell, R. B., Dec 17 2013, In : PloS one. 8, 12, e84357.

Research output: Contribution to journalArticle

28 Scopus citations

Respiratory effects of ASI-222 HCl, an aminosugar cardiac glycoside

Cook, L. S., Caldwell, R. W. & Nash, C. B., Jan 1 1978, In : Pharmacologist. 20, 3, 1 p.

Research output: Contribution to journalArticle

Reversal of effects of morphine by nalmefene

Nagarajan, R., Jeyashree, S., Shanmugam, M., Bala Subramanian, V., Tuttle, R. R. & Caldwell, R. W., Jan 1 1993, In : Journal of Clinical Research and Drug Development. 7, 1, p. 25-29 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
3 Scopus citations

Role of cardiac beta-adrenergic receptors in the cardiac toxicity of digoxin and an aminosugar cardenolide

Puryear, S. K., Nash, C. B. & Caldwell, R. W., Jan 1 1978, In : Federation Proceedings. 37, 3

Research output: Contribution to journalArticle