• 1193 Citations
  • 21 h-Index
20052019
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Research Output 2005 2019

  • 1193 Citations
  • 21 h-Index
  • 52 Article
  • 2 Review article
  • 1 Comment/debate
2019

Differential mechanisms of adenosine- and ATPγS-induced microvascular endothelial barrier strengthening

Bátori, R., Kumar, S., Bordán, Z., Cherian-Shaw, M., Kovács-Kása, A., MacDonald, J. A., Fulton, D. J., Erdődi, F. & Verin, A. D., May 1 2019, In : Journal of Cellular Physiology. 234, 5, p. 5863-5879 17 p.

Research output: Contribution to journalArticle

Endothelial cells
Adenosine
Endothelial Cells
Cyclic AMP-Dependent Protein Kinases
Cyclic AMP
2018
1 Citation (Scopus)

A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome

Benson, T. W., Weintraub, N. L., Kim, H. W., Seigler, N., Kumar, S., Pye, J., Horimatsu, T., Pellenberg, R., Stepp, D. W., Lucas, R., Bogdanov, V. Y., Litwin, S. E., Brittain, J. E. & Harris, R. A., Oct 1 2018, In : Laboratory Investigation. 98, 10, p. 1300-1310 11 p.

Research output: Contribution to journalArticle

Acute Coronary Syndrome
Peroxidase
Meals
Erythrocytes
Fats
11 Citations (Scopus)

LPS-induced acute lung injury involves NF-kB–mediated downregulation of SOX18

Gross, C. M., Kellner, M., Wang, T., Lu, Q., Sun, X., Zemskov, E. A., Noonepalle, S., Kangath, A., Kumar, S., Gonzalez-Garay, M., Desai, A. A., Aggarwal, S., Gorshkov, B., Klinger, C., Verin, A. D., Catravas, J. D., Jacobson, J. R., Yuan, J. X. J., Rafikov, R., Garcia, J. G. N. & 1 others, Black, S. M., May 1 2018, In : American journal of respiratory cell and molecular biology. 58, 5, p. 614-624 11 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Endothelial cells
Down-Regulation
Lung
NF-kappa B
2017
4 Citations (Scopus)

Altered carnitine homeostasis in children with increased pulmonary blood flow due to ventricular septal defects

Black, S. M., Field-Ridley, A., Sharma, S., Kumar, S., Keller, R. L., Kameny, R., Maltepe, E., Datar, S. A. & Fineman, J. R., Oct 1 2017, In : Pediatric Critical Care Medicine. 18, 10, p. 931-934 4 p.

Research output: Contribution to journalArticle

Carnitine
Ventricular Heart Septal Defects
Homeostasis
Lung
Heart Diseases
2 Citations (Scopus)

Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury

Kumar, S., Sun, X., Noonepalle, S. K., Lu, Q., Zemskov, E. A., Wang, T., Aggarwal, S., Gross, C., Sharma, S., Desai, A. A., Hou, Y., Dasarathy, S., Qu, N., Reddy, V., Lee, S. G., Cherian-Shaw, M., Yuan, J. X. J., Catravas, J. D., Rafikov, R., Garcia, J. G. N. & 1 others, Black, S. M., Jan 1 2017, In : Free Radical Biology and Medicine. 102, p. 217-228 12 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Lipopolysaccharides
Nitric Oxide
Chemical activation
Nitric Oxide Synthase Type III
4 Citations (Scopus)

RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins

Chen, F., Wang, Y., Rafikov, R., Haigh, S., Kumar, S., Rafikova, O., Lucas, R., Verin, A. D., Black, S. M. & Fulton, D. J., Mar 1 2017, In : Biochemical Pharmacology. 127, p. 34-45 12 p.

Research output: Contribution to journalArticle

Bacterial Toxins
Nitric Oxide
glutathione-independent formaldehyde dehydrogenase
Lung
Calcium
2016
3 Citations (Scopus)

The protective role of MLCP-mediated ERM dephosphorylation in endotoxin-induced lung injury in vitro and in vivo

Kovacs-Kasa, A., Gorshkov, B. A., Kim, K. M., Kumar, S., Black, S. M., Fulton, D. J., Dimitropoulou, C., Catravas, J. D. & Verin, A. D., Dec 15 2016, In : Scientific Reports. 6, 39018.

Research output: Contribution to journalArticle

Lung Injury
Phosphoric Monoester Hydrolases
Endotoxins
Acute Lung Injury
Permeability
2015
27 Citations (Scopus)

Autophagy in neonatal hypoxia ischemic brain is associated with oxidative stress

Lu, Q., Harris, V. A., Kumar, S., Mansour, H. M. & Black, S. M., Dec 1 2015, In : Redox Biology. 6, p. 516-523 8 p.

Research output: Contribution to journalArticle

Brain Hypoxia
Oxidative stress
Autophagy
Brain
Oxidative Stress
21 Citations (Scopus)

Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury

Gross, C. M., Rafikov, R., Kumar, S., Aggarwal, S., Ham, P. B., Meadows, M. L., Cherian-Shaw, M., Kangath, A., Sridhar, S., Lucas, R. & Black, S. M., Mar 18 2015, In : PloS one. 10, 3, e0119918.

Research output: Contribution to journalArticle

Acute Lung Injury
Nitric Oxide Synthase Type III
lipopolysaccharides
Lipopolysaccharides
lungs
19 Citations (Scopus)

Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism

Lu, Q., Harris, V. A., Rafikov, R., Sun, X., Kumar, S. & Black, S. M., Dec 1 2015, In : Redox Biology. 6, p. 112-121 10 p.

Research output: Contribution to journalArticle

Metabolism
Hydroxyl Radical
Brain
Nitric Oxide
Ischemia
2014
18 Citations (Scopus)

Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury

Aggarwal, S., Gross, C. M., Kumar, S., Dimitropoulou, C., Sharma, S., Gorshkov, B. A., Sridhar, S., Lu, Q., Bogatcheva, N. V., Jezierska-Drutel, A. J., Lucas, R., Verin, A. D., Catravas, J. D. & Black, S. M., Mar 2014, In : American journal of respiratory cell and molecular biology. 50, 3, p. 614-625 12 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Lung
Oxidative stress
Nitration
Vascular System Injuries
30 Citations (Scopus)

Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase

Sun, X., Kumar, S., Sharma, S., Aggarwal, S., Lu, Q., Gross, C., Rafikova, O., Lee, S. G., Dasarathy, S., Hou, Y., Meadows, M. L., Han, W., Su, Y., Fineman, J. R. & Black, S. M., Jan 1 2014, In : American journal of respiratory cell and molecular biology. 50, 6, p. 1084-1095 12 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Endothelial cells
Endothelin-1
Pulmonary Hypertension
Endothelial Cells
13 Citations (Scopus)

Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167

Rafikov, R., Kumar, S., Aggarwal, S., Hou, Y., Kangath, A., Pardo, D., Fineman, J. R. & Black, S. M., Feb 1 2014, In : Free Radical Biology and Medicine. 67, p. 255-264 10 p.

Research output: Contribution to journalArticle

Phosphorylation
Endothelin-1
Catalase
Serine
Protein Kinase C
32 Citations (Scopus)

Heat shock protein 90 inhibitors prevent lps-induced endothelial barrier dysfunction by disrupting Rhoa signaling

Joshi, A. D., Dimitropoulou, C., Thangjam, G., Snead, C., Feldman, S., Barabutis, N., Fulton, D. J., Hou, Y., Kumar, S., Patel, V. S., Gorshkov, B. A., Verin, A. D., Black, S. M. & Catravas, J. D., Jan 1 2014, In : American journal of respiratory cell and molecular biology. 50, 1, p. 170-179 10 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
tanespimycin
Endothelial cells
Myosin Light Chains
Phosphorylation
17 Citations (Scopus)

Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding

Aggarwal, S., Gross, C. M., Rafikov, R., Kumar, S., Fineman, J. R., Ludewig, B., Jonigk, D. & Black, S. M., Mar 14 2014, In : Journal of Biological Chemistry. 289, 11, p. 7948-7961 14 p.

Research output: Contribution to journalArticle

Nitration
Cyclic GMP-Dependent Protein Kinases
Cyclic GMP
Tyrosine
Smooth Muscle Myocytes
29 Citations (Scopus)

PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins

Chen, F., Kumar, S., Yu, Y., Aggarwal, S., Gross, C., Wang, Y., Chakraborty, T., Verin, A. D., Catravas, J. D., Lucas, R., Black, S. M. & Fulton, D. J., Jul 14 2014, In : PloS one. 9, 7, e99823.

Research output: Contribution to journalArticle

Phosphorylation
Nitric Oxide Synthase Type III
phosphorylation
toxins
Endothelial cells
3 Citations (Scopus)

Protein engineering to develop a redox insensitive endothelial nitric oxide synthase

Rafikov, R., Kumar, S., Aggarwal, S., Pardo, D., Fonseca, F. V., Ransom, J., Rafikova, O., Chen, Q., Springer, M. L. & Black, S. M., Jan 1 2014, In : Redox Biology. 2, 1, p. 156-164 9 p.

Research output: Contribution to journalArticle

Protein Engineering
Nitric Oxide Synthase Type III
Oxidation-Reduction
Dimers
Endothelial cells
5 Citations (Scopus)

Sox18 Preserves the Pulmonary Endothelial Barrier Under Conditions of Increased Shear Stress

Gross, C. M., Aggarwal, S., Kumar, S., Tian, J., Kasa, A., Bogatcheva, N., Datar, S. A., Verin, A. D., Fineman, J. R. & Black, S. M., Jan 1 2014, In : Journal of Cellular Physiology. 229, 11, p. 1802-1816 15 p.

Research output: Contribution to journalArticle

Claudin-5
Shear stress
Lung
Blood
Endothelial cells
2013
37 Citations (Scopus)

Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonaryhypertension

Rafikova, O., Rafikov, R., Kumar, S., Sharma, S., Aggarwal, S., Schneider, F., Jonigk, D., Black, S. M. & Tofovic, S. P., Mar 1 2013, In : Free Radical Biology and Medicine. 56, p. 28-43 16 p.

Research output: Contribution to journalArticle

Oxidative stress
Pulmonary Hypertension
Endothelin-1
Oxidative Stress
Cell proliferation
18 Citations (Scopus)

Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow

Sun, X., Sharma, S., Fratz, S., Kumar, S., Rafikov, R., Aggarwal, S., Rafikova, O., Lu, Q., Burns, T., Dasarathy, S., Wright, J., Schreiber, C., Radman, M., Fineman, J. R. & Black, S. M., May 10 2013, In : Antioxidants and Redox Signaling. 18, 14, p. 1739-1752 14 p.

Research output: Contribution to journalReview article

Carnitine
Endothelial cells
Energy Metabolism
Blood
Endothelial Cells

Erratum: Rosiglitazone preserves pulmonary vascular function in lambs with increased pulmonary blood flow (Pediatric Research (2013) 73 (54-61) DOI: 10.1038/pr.2012.149)

Oishi, P. E., Sharma, S., Datar, S. A., Kumar, S., Aggarwal, S., Lu, Q., Raff, G., Azakie, A., Hsu, J. H., Sajti, E., Fratz, S., Black, S. M. & Fineman, J. R., Dec 1 2013, In : Pediatric research. 74, 6, 1 p.

Research output: Contribution to journalComment/debate

rosiglitazone
Blood Vessels
Pediatrics
Lung
Research
15 Citations (Scopus)

L-Carnitine preserves endothelial function in a lamb model of increased pulmonary blood flow

Sharma, S., Aramburo, A., Rafikov, R., Sun, X., Kumar, S., Oishi, P. E., Datar, S. A., Raff, G., Xoinis, K., Kalkan, G., Fratz, S., Fineman, J. R. & Black, S. M., Jul 1 2013, In : Pediatric Research. 74, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Carnitine
Lung
Nitric Oxide Synthase Type III
Acetylcarnitine
Transferases
18 Citations (Scopus)

LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung

Barabutis, N., Handa, V., Dimitropoulou, C., Rafikov, R., Snead, C., Kumar, S., Joshi, A., Thangjam, G., Fulton, D., Black, S. M., Patel, V. & Catravas, J. D., Jun 15 2013, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 304, 12, p. L883-l893

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Tyrosine
Endothelial Cells
Phosphorylation
Lung
14 Citations (Scopus)

Peroxynitrite mediates testosterone-induced vasodilation of microvascular resistance vessels

Puttabyatappa, Y., Stallone, J. N., Ergul, A., El-Remessy, A. B., Kumar, S., Black, S. M., Johnson, M. H., Owen, M. P. & White, R. E., Apr 1 2013, In : Journal of Pharmacology and Experimental Therapeutics. 345, 1, p. 7-14 8 p.

Research output: Contribution to journalArticle

Peroxynitrous Acid
Vasodilation
Testosterone
Microvessels
Superoxides
7 Citations (Scopus)

Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells

Sharma, S., Sun, X., Agarwal, S., Rafikov, R., Dasarathy, S., Kumar, S. & Black, S. M., Jan 1 2013, In : International journal of molecular sciences. 14, 1, p. 255-272 18 p.

Research output: Contribution to journalArticle

carnitine
Acetylcarnitine
Endothelial cells
Nitric oxide
nitric oxide
6 Citations (Scopus)

Rosiglitazone preserves pulmonary vascular function in lambs with increased pulmonary blood flow

Oishi, P. E., Sharma, S., Datar, S. A., Kumar, S., Aggarwal, S., Lu, Q., Raff, G., Azakie, A., Hsu, J. H., Sajti, E., Fratz, S., Black, S. M. & Fineman, J. R., Jan 1 2013, In : Pediatric Research. 73, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

rosiglitazone
Peroxisome Proliferator-Activated Receptors
Blood Vessels
Lung
Pulmonary Artery
5 Citations (Scopus)

Tezosentan increases nitric oxide signaling via enhanced hydrogen peroxide generation in lambs with surgically induced acute increases in pulmonary blood flow

Kumar, S., Oishi, P. E., Rafikov, R., Aggarwal, S., Hou, Y., Datar, S. A., Sharma, S., Azakie, A., Fineman, J. R. & Black, S. M., Feb 1 2013, In : Journal of cellular biochemistry. 114, 2, p. 435-447 13 p.

Research output: Contribution to journalArticle

Hydrogen Peroxide
Nitric Oxide
Blood
Lung
Endothelin-1
2012
46 Citations (Scopus)

Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice

Anea, C. B., Cheng, B., Sharma, S., Kumar, S., Caldwell, R. W., Yao, L., Ali, M. I., Merloiu, A. M., Stepp, D. W., Black, S. M., Fulton, D. J. & Rudic, R. D., Oct 12 2012, In : Circulation research. 111, 9, p. 1157-1165 9 p.

Research output: Contribution to journalArticle

Circadian Clocks
Knockout Mice
Nitric Oxide Synthase
Superoxides
Blood Vessels
21 Citations (Scopus)

PPAR-γ Regulates Carnitine Homeostasis and Mitochondrial Function in a Lamb Model of Increased Pulmonary Blood Flow

Sharma, S., Sun, X., Rafikov, R., Kumar, S., Hou, Y., Oishi, P. E., Datar, S. A., Raff, G., Fineman, J. R. & Black, S. M., Sep 4 2012, In : PloS one. 7, 9, e41555.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Carnitine
carnitine
blood flow
homeostasis
14 Citations (Scopus)

Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase i

Sharma, S., Sun, X., Kumar, S., Rafikov, R., Aramburo, A., Kalkan, G., Tian, J., Rehmani, I., Kallarackal, S., Fineman, J. R. & Black, S. M., Jul 15 2012, In : Free Radical Biology and Medicine. 53, 2, p. 216-229 14 p.

Research output: Contribution to journalArticle

GTP Cyclohydrolase
Carnitine
Degradation
Ubiquitination
Pulmonary Hypertension
2011
18 Citations (Scopus)

Attenuated vasodilatation in lambs with endogenous and exogenous activation of cGMP signaling: Role of protein kinase G nitration

Aggarwal, S., Gross, C. M., Kumar, S., Datar, S., Oishi, P., Kalkan, G., Schreiber, C., Fratz, S., Fineman, J. R. & Black, S. M., Dec 1 2011, In : Journal of Cellular Physiology. 226, 12, p. 3104-3113 10 p.

Research output: Contribution to journalReview article

Nitration
Cyclic GMP-Dependent Protein Kinases
Cyclic GMP
Vasodilation
Chemical activation
16 Citations (Scopus)

C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow

Sun, X., Fratz, S., Sharma, S., Hou, Y., Rafikov, R., Kumar, S., Rehmani, I., Tian, J., Smith, A., Schreiber, C., Reiser, J., Naumann, S., Haag, S., Hess, J., Catravas, J. D., Patterson, C., Fineman, J. R. & Black, S. M., Jul 1 2011, In : American journal of respiratory cell and molecular biology. 45, 1, p. 163-171 9 p.

Research output: Contribution to journalArticle

GTP Cyclohydrolase
HSP70 Heat-Shock Proteins
Guanosine
Guanosine Triphosphate
Blood
128 Citations (Scopus)

eNOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity

Rafikov, R., Fonseca, F. V., Kumar, S., Pardo, D., Darragh, C., Elms, S., Fulton, D. J. & Black, S. M., Sep 1 2011, In : Journal of Endocrinology. 210, 3, p. 271-284 14 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Nucleic Acid Regulatory Sequences
Post Translational Protein Processing
Superoxides
Oxidative Stress
4 Citations (Scopus)

Purification and functional analysis of protein kinase G-1α using a bacterial expression system

Aggarwal, S., Rafikov, R., Gross, C. M., Kumar, S., Pardo, D. & Black, S. M., Oct 1 2011, In : Protein Expression and Purification. 79, 2, p. 271-276 6 p.

Research output: Contribution to journalArticle

Cyclic GMP-Dependent Protein Kinases
Cyclic GMP
Enzymes
Adenosine Triphosphate
Guanosine Monophosphate
50 Citations (Scopus)

The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells

Ganapathy, P. S., White, R. E., Ha, Y., Renee Bozard, B., McNeil, P. L., Caldwell, R. W., Kumar, S., Black, S. M. & Smith, S. B., Jul 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5515-5524 10 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Homocysteine
N-Methyl-D-Aspartate Receptors
D-Aspartic Acid
Ganglia
2010
11 Citations (Scopus)

Inhibition of endothelial nitric oxide synthase by the lipid phosphatase PTEN

Church, J. E., Qian, J., Kumar, S., Black, S. M., Venema, R. C., Papapetropoulos, A. & Fulton, D. J., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 191-198 8 p.

Research output: Contribution to journalArticle

PTEN Phosphohydrolase
Nitric Oxide Synthase Type III
Phosphorylation
Lipids
1-Phosphatidylinositol 4-Kinase
31 Citations (Scopus)

Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: Role of asymmetric dimethylarginine

Sharma, S., Smith, A., Kumar, S., Aggarwal, S., Rehmani, I., Snead, C., Harmon, C., Fineman, J., Fulton, D. J., Catravas, J. D. & Black, S. M., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 182-190 9 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Endotoxins
Nitric Oxide Synthase
Lipopolysaccharides
Lung
13 Citations (Scopus)

Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow

Sharma, S., Kumar, S., Wiseman, D. A., Kallarackal, S., Ponnala, S., Elgaish, M., Tian, J., Fineman, J. R. & Black, S. M., Jul 1 2010, In : Vascular Pharmacology. 53, 1-2, p. 38-52 15 p.

Research output: Contribution to journalArticle

Xanthine Oxidase
Superoxides
Sheep
NADP
Oxidoreductases
36 Citations (Scopus)
Catalase
Protein Kinase C
Nitric Oxide
Endothelial Cells
Phosphorylation
23 Citations (Scopus)

The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - A crucial role for protein kinase C-α inhibition

Xiong, C., Yang, G., Kumar, S., Aggarwal, S., Leustik, M., Snead, C., Hamacher, J., Fischer, B., Siddaramappa, U. N., Hossain, H., Wendel, A., Catravas, J. D., Verin, A. D., Fulton, D. J., Black, S. M., Chakraborty, T. & Lucas, R., May 1 2010, In : Vascular Pharmacology. 52, 5-6, p. 207-213 7 p.

Research output: Contribution to journalArticle

Lectins
Protein Kinase C
Myosin Light Chains
Endothelial Cells
Lung
29 Citations (Scopus)

The lectin-like doMain of tumor necrosis factor improves lung function after rat lung transplantation-Potential role for a reduction in reactive oxygen species generation

Hamacher, J., Stammberger, U., Roux, J., Kumar, S., Yang, G., Xiong, C., Schmid, R. A., Fakin, R. M., Chakraborty, T., Hossain, H. M. D., Pittet, J. F., Wendel, A., Black, S. M. & Lucas, R., Jan 1 2010, In : Critical care medicine. 38, 3, p. 871-878 8 p.

Research output: Contribution to journalArticle

Lung Transplantation
Lectins
Reactive Oxygen Species
Tumor Necrosis Factor-alpha
Lung
2009
12 Citations (Scopus)

Alterations in lung arginine metabolism in lambs with pulmonary hypertension associated with increased pulmonary blood flow

Sharma, S., Kumar, S., Sud, N., Wiseman, D. A., Tian, J., Rehmani, I., Datar, S., Oishi, P., Fratz, S., Venema, R. C., Fineman, J. R. & Black, S. M., Nov 1 2009, In : Vascular Pharmacology. 51, 5-6, p. 359-364 6 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Arginine
Lung
Nitric Oxide
Argininosuccinate Lyase
34 Citations (Scopus)

Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: Gene profiling in pulmonary hypertension

Tian, J., Smith, A., Nechtman, J., Podolsky, R., Aggarwal, S., Snead, C., Kumar, S., Elgaish, M., Oishi, P., Göerlach, A., Fratz, S., Hess, J., Catravas, J. D., Verin, A. D., Fineman, J. R., She, J-X. & Black, S. M., Jan 1 2009, In : Physiological Genomics. 40, 1, p. 48-60 13 p.

Research output: Contribution to journalArticle

PPAR gamma
Gene Expression Profiling
Pulmonary Hypertension
Endothelial Cells
Lung
8 Citations (Scopus)
GTP Cyclohydrolase
Response Elements
Guanosine Triphosphate
Cyclic AMP
Estradiol
12 Citations (Scopus)

GTP cyclohydrolase I expression is regulated by nitric oxide: Role of cyclic AMP

Kumar, S., Sun, X., Sharma, S., Aggarwal, S., Ravi, K., Fineman, J. R. & Black, S. M., Aug 1 2009, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 297, 2

Research output: Contribution to journalArticle

GTP Cyclohydrolase
Cyclic AMP
Nitric Oxide
Cyclic AMP Response Element-Binding Protein
Pteridines
16 Citations (Scopus)

Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of Sp1 activity

Kumar, S., Sun, X., Wiseman, D. A., Tian, J., Siddaramappa, U. N., Verin, A. D. & Black, S. M., Mar 1 2009, In : DNA and Cell Biology. 28, 3, p. 119-129 11 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Hydrogen Peroxide
Transcription Factor AP-1
Hydroxyl Radical
Zinc
13 Citations (Scopus)
Nitric Oxide Synthase Type III
Bryostatins
Phosphorylation
Transfection
Nitric Oxide
2008
48 Citations (Scopus)

Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension

Sharma, S., Sud, N., Wiseman, D. A., Carter, A. L., Kumar, S., Hou, Y., Rau, T., Wilham, J., Harmon, C., Oishi, P., Fineman, J. R. & Black, S. M., Jan 1 2008, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 294, 1

Research output: Contribution to journalArticle

Carnitine
Pulmonary Hypertension
Nitric Oxide
Homeostasis
Carnitine O-Acetyltransferase
33 Citations (Scopus)
Nitric Oxide Synthase Type III
Transcription Factor AP-1
Hydrogen Peroxide
Protein Binding
Carrier Proteins
30 Citations (Scopus)

Progressive dysfunction of nitric oxide synthase in a lamb model of chronically increased pulmonary blood flow: A role for oxidative stress

Oishi, P. E., Wiseman, D. A., Sharma, S., Kumar, S., Hou, Y., Datar, S. A., Azakie, A., Johengen, M. J., Harmon, C., Fratz, S., Fineman, J. R. & Black, S. M., Nov 1 2008, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 295, 5

Research output: Contribution to journalArticle

Nitric Oxide Synthase
Oxidative Stress
Nitric Oxide
Lung
Pulmonary Artery