• 5720 Citations
  • 41 h-Index
1986 …2019
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Research Output 1986 2019

1986
20 Citations (Scopus)

Retinal degeneration in the mouse. A model induced transplaceatally by methylnitrosourea

Smith, S. B. & Yielding, K. L., Jan 1 1986, In : Experimental Eye Research. 43, 5, p. 791-801 11 p.

Research output: Contribution to journalArticle

Methylnitrosourea
Retinal Degeneration
Retina
Retinal Dysplasia
Teratogens
1987
5 Citations (Scopus)

Late‐onset cerebellar degeneration in mice induced transplacentally by methylnitrosourea

Smith, S. B., Brown, C. B., Wright, M. E. & Yielding, K. L., Jan 1 1987, In : Teratogenesis, Carcinogenesis, and Mutagenesis. 7, 5, p. 449-463 15 p.

Research output: Contribution to journalArticle

Methylnitrosourea
Animals
Purkinje Cells
Alkylating Agents
Cerebellar Diseases
1988
4 Citations (Scopus)
Methylnitrosourea
Phospholipids
Proteins
Rod Cell Outer Segment
Alkylating Agents
6 Citations (Scopus)
Butylated Hydroxytoluene
Retinal Degeneration
Animals
Antioxidants
Nutrition
10 Citations (Scopus)

Retinal degeneration in the mouse induced transplacentally by N-methyl-N-nitrosourea: Effects of constant illumination or total darkness

Smith, S. B., Hashimi, W. & Yielding, K. L., Jan 1 1988, In : Experimental Eye Research. 47, 3, p. 347-359 13 p.

Research output: Contribution to journalArticle

Methylnitrosourea
Retinal Degeneration
Darkness
Lighting
Light
1989
22 Citations (Scopus)

Acetylcholine's effect on vascular resistance and compliance in the pulmonary circulation

Barman, S. A., Senteno, E., Smith, S. B. & Taylor, A. E., Jan 1 1989, In : Journal of Applied Physiology. 67, 4, p. 1495-1503 9 p.

Research output: Contribution to journalArticle

Pulmonary Circulation
Vascular Resistance
Compliance
Acetylcholine
Blood Vessels
12 Citations (Scopus)

Addition of the chromophore to rat rhodopsin is an early post-translational event

St Jules, R. S., Wallingford, J. C., Smith, S. B. & O'Brien, P. J., Jan 1 1989, In : Experimental Eye Research. 48, 5, p. 653-665 13 p.

Research output: Contribution to journalArticle

Rhodopsin
Rough Endoplasmic Reticulum
Rod Cell Outer Segment
Agarose Chromatography
Intravitreal Injections
3 Citations (Scopus)
Butylated Hydroxytoluene
Animals
Antioxidants
Nutrition
Purkinje Cells
1990
19 Citations (Scopus)

The localization and timing of post-translational modifications of rat rhodopsin

St Jules, R. S., Smith, S. B. & O'Brien, P. J., Jan 1 1990, In : Experimental Eye Research. 51, 4, p. 427-434 8 p.

Research output: Contribution to journalArticle

Rhodopsin
Post Translational Protein Processing
Rod Cell Outer Segment
Rough Endoplasmic Reticulum
Glucosamine
1991
8 Citations (Scopus)

Acylation and glycosylation of rhodopsin in the rd mouse

Smith, S. B. & O'Brien, P. J., Jan 1 1991, In : Experimental eye research. 52, 5, p. 599-606 8 p.

Research output: Contribution to journalArticle

Rhodopsin
Acylation
Glycosylation
Rod Cell Outer Segment
Leucine
19 Citations (Scopus)

Transient hyperglycosylation of rhodopsin with galactose

Smith, S. B., St Jules, R. S. & O'Brien, P. J., Jan 1 1991, In : Experimental eye research. 53, 4, p. 525-537 13 p.

Research output: Contribution to journalArticle

Rhodopsin
Galactose
Rod Cell Outer Segment
Oligosaccharides
Griffonia
1992
34 Citations (Scopus)
Photoreceptor Cells
Retinal Degeneration
Rhodopsin
Retina
Light
2 Citations (Scopus)

Rapid PCR-based construction of specifically enriched libraries from small retina samples

Putilina, T., Smith, S., Gentleman, S. & Chader, G., May 1992, In : Experimental eye research. 54, 5, p. 825-826 2 p.

Research output: Contribution to journalLetter

Retinal Diseases
Gene Library
Libraries
Retina
Polymerase Chain Reaction
7 Citations (Scopus)

Synthesis and secretion of interphotoreceptor retinoid-binding protein (IRBP) and developmental expression of IRBP mRNA in normal and rd mouse retinas

Smith, S. B., Lee, L., Nickerson, J., Si, J. S., Chader, G. J. & Wiggert, B., Jun 1992, In : Experimental eye research. 54, 6, p. 957-963 7 p.

Research output: Contribution to journalArticle

Retina
Messenger RNA
Methionine
interstitial retinol-binding protein
Organ Culture Techniques
1993
4 Citations (Scopus)

Opsin synthesis in the c57BL/6-mivit/mivit mouse model of retinal degeneration

Smith, S. B., McCoy, J. R. & Cope, B. K., Jan 1 1993, In : Current Eye Research. 12, 8, p. 711-717 7 p.

Research output: Contribution to journalArticle

Opsins
Retinal Degeneration
Leucine
Photoreceptor Cells
Retina
1994
17 Citations (Scopus)

Effects of Dark-rearing on the Retinal Degeneration of the C57BL/6-mivit/mivit Mouse

Smith, S. B., Cope, B. K. & McCoy, J. R., Jan 1 1994, In : Experimental eye research. 58, 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

Retinal Degeneration
Retina
Photoreceptor Cells
Rhodopsin
Lighting
24 Citations (Scopus)

Electroretinographic study of the C57BL/6-mi(vit)/mi(vit) mouse model of retinal degeneration

Smith, S. B. & Hamasaki, D. I., Jan 1 1994, In : Investigative Ophthalmology and Visual Science. 35, 7, p. 3119-3123 5 p.

Research output: Contribution to journalArticle

Retinal Degeneration
Photoreceptor Cells
Rhodopsin
Retinal Pigment Epithelium
Pigmentation
23 Citations (Scopus)

Increase in retinyl palmitate concentration in eyes and livers and the concentration of interphotoreceptor retinoid-binding protein in eyes of vitiligo mutant mice

Smith, S. B., Duncan, T., Kutty, G., Kutty, R. K. & Wiggert, B., Jan 1 1994, In : Biochemical Journal. 300, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

Vitiligo
Retinoids
Liver
Retinal Pigments
Vitamin A
29 Citations (Scopus)

Reduction of phagosomes in the vitiligo (C57BL/6-mi(vit)/mi(vit)) mouse model of retinal degeneration

Smith, S. B., Cope, B. K., McCoy, J. R., McCool, D. J. & Defoe, D. M., Jan 1 1994, In : Investigative Ophthalmology and Visual Science. 35, 10, p. 3625-3632 8 p.

Research output: Contribution to journalArticle

Phagosomes
Retinal Degeneration
Vitiligo
Retinal Pigment Epithelium
Rod Cell Outer Segment
13 Citations (Scopus)

The use of C0t-1 probe DNA for the detection of low levels of DNA fragmentation.

Wong, P., Smith, S. B., Bora, N. & Gentleman, S., Jan 1 1994, In : Biochemistry and cell biology = Biochimie et biologie cellulaire. 72, 11-12, p. 649-653 5 p.

Research output: Contribution to journalArticle

DNA Probes
DNA Fragmentation
DNA
Ladders
Ethidium
1995
9 Citations (Scopus)
Rod Cell Outer Segment
Retinal Degeneration
Vitiligo
Retina
Radioactivity
17 Citations (Scopus)
Photoreceptor Cells
Vitiligo
Inbred C57BL Mouse
Retina
Guinea Pigs
40 Citations (Scopus)

Photoreceptor cells in the vitiligo mouse die by apoptosis: TRPM- 2/clusterin expression is increased in the neural retina and in the retinal pigment epithelium

Smith, S. B., Bora, N., McCool, D., Kutty, G., Wong, P., Kutty, R. K. & Wiggert, B., Jan 1 1995, In : Investigative Ophthalmology and Visual Science. 36, 11, p. 2193-2201 9 p.

Research output: Contribution to journalArticle

Clusterin
Photoreceptor Cells
Vitiligo
Retinal Pigment Epithelium
Retina
22 Citations (Scopus)

Ultrastructural features of retinal dystrophy in mutant vitiligo mice

Nir, I., Ransom, N. & Smith, S. B., Jan 1 1995, In : Experimental eye research. 61, 3, p. 363-377 15 p.

Research output: Contribution to journalArticle

Retinal Dystrophies
Vitiligo
Epithelium
Melanosomes
Rod Cell Outer Segment
1996

Abnormalities of the retinal pigment epithelium in transgenic mice with APC gene modification

Coulter, E., Rustgi, A., Defoe, D., Smith, S., Kucherlapati, R. & Marcus, D., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S383

Research output: Contribution to journalArticle

APC Genes
Retinal Pigment Epithelium
Transgenic Mice
Histology
Photoreceptor Cells

Effects of basic FGF on retinal degeneration in vitiligo (mivit/mivit) mice

Smith, S. B., Titelman, R. M. & Hamasaki, D. I., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Degeneration
Vitiligo
Photoreceptor Cells
Phagocytosis
Injections
11 Citations (Scopus)
Retinal Degeneration
Vitiligo
Fibroblast Growth Factor 2
Photoreceptor Cells
Heparin
Vitiligo
Retina
Photoreceptor Cells
In Vitro Techniques
Phagocytosis
1997
9 Citations (Scopus)
Vitiligo
Retinal Pigments
Esterification
Retinoids
Esters
3 Citations (Scopus)

Ciliary neurotrophic factor (CNTF) induces reactive gliosis and gfap expression in müller cells

Sarthy, V., Brodjian, S. J. & Smith, S. B., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4

Research output: Contribution to journalArticle

Ciliary Neurotrophic Factor
Gliosis
Glial Fibrillary Acidic Protein
Retina
Staining and Labeling
10 Citations (Scopus)

Delayed rhodopsin regeneration and altered distribution of interphotoreceptor retinoid binding protein (IRBP) in the mi(vit)/mi(vit) (vitiligo) mouse

Smith, S. B., McClung, J., Wiggert, B. N. & Nir, I., Oct 20 1997, In : Journal of Neurocytology. 26, 9, p. 605-613 9 p.

Research output: Contribution to journalArticle

Vitiligo
Rhodopsin
Regeneration
Retina
Retinal Pigment Epithelium
Microphthalmos
Vitiligo
Choroid
Monophenol Monooxygenase
Genes
10 Citations (Scopus)

Glial fibrillary acidic protein (GFAP) is synthesized in the early stages of the photoreceptor cell degeneration of the mivit/mivit (vitiligo) mouse.

Smith, S. B., Brodjian, S., Desai, S. & Sarthy, V., Jan 1 1997, In : Experimental eye research. 64, 4, p. 645-650 6 p.

Research output: Contribution to journalArticle

Mutant Strains Mice
Retinal Diseases
Photoreceptor Cells
Vitiligo
Glial Fibrillary Acidic Protein
27 Citations (Scopus)

Retinal pigment epithelium abnormalities in mice with adenomatous polyposis coli gene disruption

Marcus, D. M., Rustgi, A. K., Defoe, D., Brooks, S. E., McCormick, R. S., Thompson, T. P., Edelmann, W., Kucherlapati, R. & Smith, S. B., Jan 1 1997, In : Archives of Ophthalmology. 115, 5, p. 645-650 6 p.

Research output: Contribution to journalArticle

APC Genes
Retinal Pigment Epithelium
Adenomatous Polyposis Coli
Codon
Retina
1998
22 Citations (Scopus)
Microphthalmia-Associated Transcription Factor
Vitiligo
Monophenol Monooxygenase
Choroid
Proteins
26 Citations (Scopus)

Transient overexpression of the microphthalmia gene in the eyes of microphthalmia vitiligo mutant mice

Bora, N., Conway, S. J., Liang, H. & Smith, S. B., Nov 1 1998, In : Developmental Dynamics. 213, 3, p. 283-292 10 p.

Research output: Contribution to journalArticle

Microphthalmos
Vitiligo
Retinal Pigment Epithelium
Pigmentation
Genes
1999
7 Citations (Scopus)

Evidence of decreased adhesion between the neural retina and retinal pigmented epithelium of the Mitf(vit) (vitiligo) mutant mouse

Bora, N., Defoe, D. & Smith, S. B., Jan 11 1999, In : Cell and Tissue Research. 295, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Vitiligo
Retina
Epithelium
Photoreceptor Cells
Retinal Photoreceptor Cell Outer Segment
35 Citations (Scopus)

Expression of folate receptor α in the mammalian retinol pigmented epithelium and retina

Smith, S. B., Kekuda, R., Gu, X., Chancy, C., Conway, S. J. & Ganapathy, V., Apr 13 1999, In : Investigative Ophthalmology and Visual Science. 40, 5, p. 840-848 9 p.

Research output: Contribution to journalArticle

Vitamin A
Folic Acid
Retinal Pigments
Retina
Epithelium
20 Citations (Scopus)

Functional dissection of the promoter of the interphotoreceptor retinoid-binding protein gene: The cone-rod-homeobox element is essential for photoreceptor-specific expression in vivo

Fei, Y., Matragoon, S., Smith, S. B., Overbeek, P. A., Chen, S., Zack, D. J. & Liou, G. I., Jan 1 1999, In : Journal of Biochemistry. 125, 6, p. 1189-1199 11 p.

Research output: Contribution to journalArticle

Dissection
Vertebrate Photoreceptor Cells
Homeobox Genes
Cones
Genes
8 Citations (Scopus)

Levels of retinoic acid and retinaldehyde dehydrogenase expression in eyes of the Mitfvit mouse model of retinal degeneration

Duncan, T., Swint, C., Smith, S. B. & Wiggert, B. N., Jan 1 1999, In : Molecular Vision. 5, 9

Research output: Contribution to journalArticle

Retinaldehyde
Retinal Degeneration
Tretinoin
Oxidoreductases
Retina

Levels of retinoic acid and retinaldehyde dehydrogenase expression in eyes of the Mitf-vit mouse model of retinal degeneration.

Duncan, T., Swint, C., Smith, S. B. & Wiggert, B. N., Jun 28 1999, In : Molecular Vision. 5

Research output: Contribution to journalArticle

Retinaldehyde
Retinal Degeneration
Tretinoin
Oxidoreductases
Retina
174 Citations (Scopus)

Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations

Cayouette, M., Smith, S. B., Becerra, S. P. & Gravel, C., Jan 1 1999, In : Neurobiology of Disease. 6, 6, p. 523-532 10 p.

Research output: Contribution to journalArticle

Retinal Degeneration
Serine Proteinase Inhibitors
Retinitis Pigmentosa
Retinal Pigments
Retinoblastoma
25 Citations (Scopus)

Regulation of the reduced-folate transporter by nitric oxide in cultured human retinal pigment epithelial cells

Smith, S. B., Huang, W., Chancy, C. & Ganapathy, V., Apr 13 1999, In : Biochemical and Biophysical Research Communications. 257, 2, p. 279-283 5 p.

Research output: Contribution to journalArticle

Folic Acid Transporters
Retinal Pigments
Nitric Oxide
Epithelial Cells
Sulfhydryl Compounds
19 Citations (Scopus)

Stable and efficient gene transfer into the mutant retinal pigment epithelial cells of the Mitf(vit) mouse using a lentiviral vector

Galileo, D. S., Hunter, K. & Smith, S. B., Jan 1 1999, In : Current Eye Research. 18, 2, p. 135-142 8 p.

Research output: Contribution to journalArticle

Retinal Pigments
Epithelial Cells
Vitiligo
Microphthalmos
Photoreceptor Cells
2000
112 Citations (Scopus)

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor α in mammalian retinal pigment epithelium

Chancy, C. D., Kekuda, R., Huang, W., Prasad, P. D., Kuhnel, J. M., Sirotnak, F. M., Roon, P., Ganapathy, V. & Smith, S. B., Jul 7 2000, In : Journal of Biological Chemistry. 275, 27, p. 20676-20684 9 p.

Research output: Contribution to journalArticle

Reduced Folate Carrier Protein
Retinal Pigments
Retinal Pigment Epithelium
Folic Acid
Polarization
49 Citations (Scopus)

Expression of the extraneuronal monoamine transporter in RPE and neural retina

Rajan, P. D., Kekuda, R., Chancy, C. D., Huang, W., Ganapathy, V. & Smith, S. B., Jan 1 2000, In : Current Eye Research. 20, 3, p. 195-204 10 p.

Research output: Contribution to journalArticle

Retina
Cations
Histamine
Dopamine
Dopamine Plasma Membrane Transport Proteins
78 Citations (Scopus)

The rhodopsin cycle is preserved in IRBP 'knockout' mice despite abnormalities in retinal structure and function

Ripps, H., Peachey, N. S., Xu, X., Nozell, S. E., Smith, S. B. & Liou, G. I., Jan 1 2000, In : Visual Neuroscience. 17, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

Rhodopsin
Knockout Mice
Retinoids
Retina
Light
5 Citations (Scopus)

Ultrastructural and ERG findings in mice with adenomatous polyposis coli gene disruption

Marcus, D. M., Rustgi, A. K., Defoe, D., Kucherlapati, R., Edelmann, W., Hamasaki, D., Liou, G. I. & Smith, S. B., Dec 1 2000, In : Molecular Vision. 6, 23, p. 169-177 9 p.

Research output: Contribution to journalArticle

APC Genes
Adenomatous Polyposis Coli
Light
Mutation
Codon
2001
17 Citations (Scopus)

A comparison of caveolae and caveolin-1 to folate receptor α in retina and retinal pigment epithelium

Bridges, C. C., El-Sherbeny, A., Roon, P., Shamsul Ola, M., Kekuda, R., Ganapathy, V., Cameron, R. S., Cameron, P. L. & Smith, S. B., Jan 1 2001, In : Histochemical Journal. 33, 3, p. 149-158 10 p.

Research output: Contribution to journalArticle

Caveolin 1
Caveolae
Retinal Pigment Epithelium
Folic Acid
Retina
118 Citations (Scopus)

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine

Martin, P. M., El-sherbeny, A., Roon, P., Schoenlein, P. V., Ganapathy, V. & Smith, S. B., Jan 1 2001, In : Experimental Eye Research. 73, 1, p. 45-57 13 p.

Research output: Contribution to journalArticle

Excitatory Amino Acids
Retinal Ganglion Cells
Homocysteine
Cell Death
Ganglia