• 6113 Citations
  • 42 h-Index
1986 …2020

Research output per year

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Research Output

Article

Stable and efficient gene transfer into the mutant retinal pigment epithelial cells of the Mitf(vit) mouse using a lentiviral vector

Galileo, D. S., Hunter, K. & Smith, S. B., Feb 1999, In : Current Eye Research. 18, 2, p. 135-142 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain

Inoue, K., Zhuang, L., Maddox, D. M., Smith, S. B. & Ganapathy, V., Oct 18 2002, In : Journal of Biological Chemistry. 277, 42, p. 39469-39476 8 p.

Research output: Contribution to journalArticle

78 Scopus citations

Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells

Bridges, C. C., Kekuda, R., Wang, H., Prasad, P. D., Mehta, P., Huang, W., Smith, S. B. & Ganapathy, V., Jan 30 2001, In : Investigative Ophthalmology and Visual Science. 42, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

100 Scopus citations

Synthesis and secretion of interphotoreceptor retinoid-binding protein (IRBP) and developmental expression of IRBP mRNA in normal and rd mouse retinas

Smith, S. B., Lee, L., Nickerson, J., Si, J. S., Chader, G. J. & Wiggert, B., Jun 1992, In : Experimental eye research. 54, 6, p. 957-963 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
3 Scopus citations

The localization and timing of post-translational modifications of rat rhodopsin

St Jules, R. S., Smith, S. B. & O'Brien, P. J., Jan 1 1990, In : Experimental Eye Research. 51, 4, p. 427-434 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

The molecular chaperone sigma 1 receptor mediates rescue of retinal cone photoreceptor cells via modulation of NRF2

Wang, J., Zhao, J., Cui, X., Mysona, B. A., Navneet, S., Saul, A., Ahuja, M., Lambert, N., Gazaryan, I. G., Thomas, B., Bollinger, K. E. & Smith, S. B., Apr 2019, In : Free Radical Biology and Medicine. 134, p. 604-616 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

The rhodopsin cycle is preserved in IRBP 'knockout' mice despite abnormalities in retinal structure and function

Ripps, H., Peachey, N. S., Xu, X., Nozell, S. E., Smith, S. B. & Liou, G. I., Jan 1 2000, In : Visual Neuroscience. 17, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells

Ganapathy, P. S., White, R. E., Ha, Y., Renee Bozard, B., McNeil, P. L., Caldwell, R. W., Kumar, S., Black, S. M. & Smith, S. B., Jul 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5515-5524 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

The role of sigma1R in mammalian retina

Wang, J., Cui, X., Roon, P., Saul, A. & Smith, S. B., Jan 1 2017, In : Advances in experimental medicine and biology. 964, p. 267-284 18 p.

Research output: Contribution to journalArticle

3 Scopus citations

The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress

Lee, H., Smith, S. B., Sheu, S. S. & Yoon, Y., May 8 2020, In : Journal of Biological Chemistry. 295, 19, p. 6543-6560 18 p.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations

The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate

Martin, P. M., Ola, M. S., Agarwal, N., Ganapathy, V. & Smith, S. B., Apr 7 2004, In : Molecular Brain Research. 123, 1-2, p. 66-75 10 p.

Research output: Contribution to journalArticle

63 Scopus citations

The use of C0t-1 probe DNA for the detection of low levels of DNA fragmentation.

Wong, P., Smith, S. B., Bora, N. & Gentleman, S., Jan 1 1994, In : Biochemistry and cell biology = Biochimie et biologie cellulaire. 72, 11-12, p. 649-653 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Transcellular transfer of folate across the retinal pigment epithelium

Bridges, C. C., El-Sherbeny, A., Ola, M. S., Ganapathy, V. & Smith, S. B., Jan 1 2002, In : Current Eye Research. 24, 2, p. 129-138 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Transient hyperglycosylation of rhodopsin with galactose

Smith, S. B., St Jules, R. S. & O'Brien, P. J., Oct 1991, In : Experimental eye research. 53, 4, p. 525-537 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Transient overexpression of the microphthalmia gene in the eyes of microphthalmia vitiligo mutant mice

Bora, N., Conway, S. J., Liang, H. & Smith, S. B., Nov 1 1998, In : Developmental Dynamics. 213, 3, p. 283-292 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Transport of Amino Acid-Based Prodrugs by the Na+- and Cl --Coupled Amino Acid Transporter ATB0,+ and Expression of the Transporter in Tissues Amenable for Drug Delivery

Hatanaka, T., Haramura, M., Fei, Y. J., Miyauchi, S., Bridges, C. C., Ganapathy, P. S., Smith, S. B., Ganapathy, V. & Ganapathy, M. E., Mar 1 2004, In : Journal of Pharmacology and Experimental Therapeutics. 308, 3, p. 1138-1147 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

Transport of D-serine via the amino acid transporter ATB0,+ expressed in the colon

Hatanaka, T., Huang, W., Nakanishi, T., Bridges, C. C., Ganapathy, V., Smith, S. B., Prasad, P. D., Ganapathy, V. & Ganapathy, M. E., Jan 1 2002, In : Biochemical and Biophysical Research Communications. 291, 2, p. 291-295 5 p.

Research output: Contribution to journalArticle

67 Scopus citations

Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis

Chothe, P. P., Gnana-Prakasam, J. P., Ananth, S., Martin, P. M., Kannan, R., Hinton, D. R., Smith, S. B. & Ganapathy, V., Feb 11 2011, In : Biochemical and Biophysical Research Communications. 405, 2, p. 244-249 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
25 Scopus citations

Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract

Gopal, E., Miyauchi, S., Martin, P. M., Ananth, S., Roon, P., Smith, S. B. & Ganapathy, V., Mar 1 2007, In : Pharmaceutical Research. 24, 3, p. 575-584 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

Transport of the synthetic opioid peptide DADLE ([d-Ala2,d-Leu5]-Enkephalin) in neuronal cells

Ananth, S., Thakkar, S. V., Gnana-prakasam, J. P., Martin, P. M., Ganapathy, P. S., Smith, S. B. & Ganapathy, V., Jan 2012, In : Journal of Pharmaceutical Sciences. 101, 1, p. 154-163 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells

Babu, E., Ananth, S., Veeranan-Karmegam, R., Coothankandaswamy, V., Smith, S. B., Boettger, T., Ganapathy, V. & Martin, P. M., Jul 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5749-5757 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Ultrastructural and ERG findings in mice with adenomatous polyposis coli gene disruption

Marcus, D. M., Rustgi, A. K., Defoe, D., Kucherlapati, R., Edelmann, W., Hamasaki, D., Liou, G. I. & Smith, S. B., Dec 1 2000, In : Molecular Vision. 6, 23, p. 169-177 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
Chapter

A Novel Mechanism of Sigma 1 Receptor Neuroprotection: Modulation of miR-214-3p

Wang, J. & Smith, S. B., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer, p. 463-467 5 p. (Advances in Experimental Medicine and Biology; vol. 1185).

Research output: Chapter in Book/Report/Conference proceedingChapter

D-serine and serine racemase in the retina

Smith, S. B., Ha, Y. & Ganapathy, V., Nov 24 2011, Amino Acids in Human Nutrition and Health. CABI Publishing, p. 137-149 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Folate Transport in Retina and Consequences on Retinal Structure and Function of Hyperhomocysteinemia

Smith, S. B., Ganapathy, P. S., Bozard, R. B. & Ganapathy, V., Apr 10 2014, Handbook of Nutrition, Diet and the Eye. Elsevier Inc., p. 349-359 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Mechanisms of ER Stress in Retinal Disease

Smith, S. B., Dec 1 2012, Retina Fifth Edition. Elsevier Inc., Vol. 1. p. 529-536 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
Comment/debate

Rapid PCR-based construction of specifically enriched libraries from small retina samples

Putilina, T., Smith, S., Gentleman, S. & Chader, G., May 1992, In : Experimental eye research. 54, 5, p. 825-826 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
Review article

Diabetic retinopathy and the NMDA receptor

Smith, S. B., Jul 2 2002, In : Drug News and Perspectives. 15, 4, p. 226-232 7 p.

Research output: Contribution to journalReview article

18 Scopus citations

Sigma 1 receptor: A novel therapeutic target in retinal disease

Smith, S. B., Wang, J., Cui, X., Mysona, B. A., Zhao, J. & Bollinger, K. E., Nov 2018, In : Progress in Retinal and Eye Research. 67, p. 130-149 20 p.

Research output: Contribution to journalReview article

13 Scopus citations

SLC19: The folate/thiamine transporter family

Ganapathy, V., Smith, S. B. & Prasad, P. D., Feb 1 2004, In : Pflugers Archiv European Journal of Physiology. 447, 5, p. 641-646 6 p.

Research output: Contribution to journalReview article

119 Scopus citations

The cystine/glutamate antiporter system xc- in health and disease: From molecular mechanisms to novel therapeutic opportunities

Lewerenz, J., Hewett, S. J., Huang, Y., Lambros, M., Gout, P. W., Kalivas, P. W., Massie, A., Smolders, I., Methner, A., Pergande, M., Smith, S. B., Ganapathy, V. & Maher, P., Feb 10 2013, In : Antioxidants and Redox Signaling. 18, 5, p. 522-555 34 p.

Research output: Contribution to journalReview article

275 Scopus citations