• 6155 Citations
  • 42 h-Index
1986 …2020

Research output per year

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Research Output

Review article

Diabetic retinopathy and the NMDA receptor

Smith, S. B., Jul 2 2002, In : Drug News and Perspectives. 15, 4, p. 226-232 7 p.

Research output: Contribution to journalReview article

18 Scopus citations

Expression and function of iron-regulatory proteins in retina

Gnana-Prakasam, J. P., Martin, P. M., Smith, S. B. & Ganapathy, V., May 1 2010, In : IUBMB Life. 62, 5, p. 363-370 8 p.

Research output: Contribution to journalReview article

32 Scopus citations

Sigma 1 receptor: A novel therapeutic target in retinal disease

Smith, S. B., Wang, J., Cui, X., Mysona, B. A., Zhao, J. & Bollinger, K. E., Nov 2018, In : Progress in Retinal and Eye Research. 67, p. 130-149 20 p.

Research output: Contribution to journalReview article

13 Scopus citations

SLC19: The folate/thiamine transporter family

Ganapathy, V., Smith, S. B. & Prasad, P. D., Feb 1 2004, In : Pflugers Archiv European Journal of Physiology. 447, 5, p. 641-646 6 p.

Research output: Contribution to journalReview article

119 Scopus citations

The cystine/glutamate antiporter system xc- in health and disease: From molecular mechanisms to novel therapeutic opportunities

Lewerenz, J., Hewett, S. J., Huang, Y., Lambros, M., Gout, P. W., Kalivas, P. W., Massie, A., Smolders, I., Methner, A., Pergande, M., Smith, S. B., Ganapathy, V. & Maher, P., Feb 10 2013, In : Antioxidants and Redox Signaling. 18, 5, p. 522-555 34 p.

Research output: Contribution to journalReview article

280 Scopus citations

Rapid PCR-based construction of specifically enriched libraries from small retina samples

Putilina, T., Smith, S., Gentleman, S. & Chader, G., May 1992, In : Experimental eye research. 54, 5, p. 825-826 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
Comment/debate
Chapter

A Novel Mechanism of Sigma 1 Receptor Neuroprotection: Modulation of miR-214-3p

Wang, J. & Smith, S. B., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer, p. 463-467 5 p. (Advances in Experimental Medicine and Biology; vol. 1185).

Research output: Chapter in Book/Report/Conference proceedingChapter

D-serine and serine racemase in the retina

Smith, S. B., Ha, Y. & Ganapathy, V., Nov 24 2011, Amino Acids in Human Nutrition and Health. CABI Publishing, p. 137-149 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Folate Transport in Retina and Consequences on Retinal Structure and Function of Hyperhomocysteinemia

Smith, S. B., Ganapathy, P. S., Bozard, R. B. & Ganapathy, V., Apr 10 2014, Handbook of Nutrition, Diet and the Eye. Elsevier Inc., p. 349-359 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Mechanisms of ER Stress in Retinal Disease

Smith, S. B., Dec 1 2012, Retina Fifth Edition. Elsevier Inc., Vol. 1. p. 529-536 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
Article

(+)-pentazocine reduces NMDA-induced murine retinal ganglion cell death through a σr1-dependent mechanism

Zhao, J., Mysona, B. A., Qureshi, A., Kim, L., Fields, T., Gonsalvez, G. B., Smith, S. B. & Bollinger, K. E., Feb 2016, In : Investigative Ophthalmology and Visual Science. 57, 2, p. 453-461 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

3-Amino-chromanes and Tetrahydroquinolines as Selective 5-HT2B, 5-HT7, or σ1 Receptor Ligands

Porter, M. R., Xiao, H., Wang, J., Smith, S. B. & Topczewski, J. J., Oct 10 2019, In : ACS Medicinal Chemistry Letters. 10, 10, p. 1436-1442 7 p.

Research output: Contribution to journalArticle

Abnormalities of the retinal pigment epithelium in transgenic mice with APC gene modification

Coulter, E., Rustgi, A., Defoe, D., Smith, S., Kucherlapati, R. & Marcus, D., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3, p. S383

Research output: Contribution to journalArticle

Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: Role of cystine/glutamate exchanger

Gnana-Prakasam, J. P., Thangaraju, M., Liu, K., Ha, Y., Martin, P. M., Smith, S. B. & Ganapathy, V., Dec 1 2009, In : Biochemical Journal. 424, 2, p. 243-252 10 p.

Research output: Contribution to journalArticle

37 Scopus citations
12 Scopus citations

Acetylcholine's effect on vascular resistance and compliance in the pulmonary circulation

Barman, S. A., Senteno, E., Smith, S. & Taylor, A. E., 1989, In : Journal of Applied Physiology. 67, 4, p. 1495-1503 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

A comparison of caveolae and caveolin-1 to folate receptor α in retina and retinal pigment epithelium

Bridges, C. C., El-Sherbeny, A., Roon, P., Shamsul Ola, M., Kekuda, R., Ganapathy, V., Cameron, R. S., Cameron, P. L. & Smith, S. B., Jan 1 2001, In : Histochemical Journal. 33, 3, p. 149-158 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
Open Access
1 Scopus citations
34 Scopus citations

Acylation and glycosylation of rhodopsin in the rd mouse

Smith, S. B. & O'Brien, P. J., May 1991, In : Experimental eye research. 52, 5, p. 599-606 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Addition of the chromophore to rat rhodopsin is an early post-translational event

St Jules, R. S., Wallingford, J. C., Smith, S. B. & O'Brien, P. J., Jan 1 1989, In : Experimental Eye Research. 48, 5, p. 653-665 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia

Yu, M., Sturgill-Short, G., Ganapathy, P., Tawfik, A. M., Peachey, N. S. & Smith, S. B., Mar 1 2012, In : Experimental eye research. 96, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

A lipidomic screen of hyperglycemia-treated hrecs links 12/15-lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase

Ibrahim, A. S., Elshafey, S., Sellak, H., Hussein, K. A., El-Sherbiny, M., Abdelsaid, M., Rizk, N., Beasley, S., Tawfik, A. M., Smith, S. B. & Al-Shabrawey, M., Mar 1 2015, In : Journal of Lipid Research. 56, 3, p. 599-611 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

Alterations of retinal vasculature in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia

Tawfik, A., Al-Shabrawey, M., Roon, P., Sonne, S., Covar, J. A., Matragoon, S., Ganapathy, P. S., Atherton, S. S., El-Remessy, A., Ganapathy, V. & Smith, S. B., Feb 2013, In : Investigative Ophthalmology and Visual Science. 54, 2, p. 939-949 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Alterations of retinal vasculature in cystathionine-β-synthase heterozygous mice: A model of mild to moderate hyperhomocysteinemia

Tawfik, A., Markand, S., Al-Shabrawey, M., Mayo, J. N., Reynolds, J., Bearden, S. E., Ganapathy, V. & Smith, S. B., Sep 2014, In : American Journal of Pathology. 184, 9, p. 2573-2585 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
9 Scopus citations

Analysis of MTHFR, CBS, glutathione, taurine, and hydrogen sulfide levels in retinas of hyperhomocysteinemic mice

Cui, X., Navneet, S., Wang, J., Roon, P., Chen, W., Xian, M. & Smith, S. B., Apr 2017, In : Investigative Ophthalmology and Visual Science. 58, 4, p. 1954-1963 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Analysis of sigma receptor (σR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice

Shamsul Ola, M., Martin, P. M., Maddox, D., El-Sherbeny, A., Huang, W., Roon, P., Agarwal, N., Ganapathy, V. & Smith, S. B., Nov 15 2002, In : Molecular Brain Research. 107, 2, p. 97-107 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine

Moore, P., El-sherbeny, A., Roon, P., Schoenlein, P. V., Ganapathy, V. & Smith, S. B., Jan 1 2001, In : Experimental eye research. 73, 1, p. 45-57 13 p.

Research output: Contribution to journalArticle

120 Scopus citations

Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses

Fouda, A. Y., Xu, Z., Shosha, E., Lemtalsi, T., Chen, J., Toque, H. A., Tritz, R., Cui, X., Stansfield, B. K., Huo, Y., Rodriguez, P. C., Smith, S. B., Caldwell, R. W., Narayanan, S. P. & Caldwell, R. B., Oct 1 2018, In : Cell Death and Disease. 9, 10, 1001.

Research output: Contribution to journalArticle

6 Scopus citations

A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

Samaddar, J. S., Gaddy, V. T., Duplantier, J., Thandavan, S. P., Shah, M., Smith, M. J., Browning, D., Rawson, J., Smith, S. B., Barrett, J. T. & Schoenlein, P. V., Oct 22 2008, In : Molecular cancer therapeutics. 7, 9, p. 2977-2987 11 p.

Research output: Contribution to journalArticle

127 Scopus citations
10 Scopus citations
4 Scopus citations

c/ebpδ null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney

Thangaraju, M., Ananth, S., Martin, P. M., Roon, P., Smith, S. B., Sterneck, E., Prasad, P. D. & Ganapathy, V., Sep 15 2006, In : Journal of Biological Chemistry. 281, 37, p. 26769-26773 5 p.

Research output: Contribution to journalArticle

55 Scopus citations
34 Scopus citations

Ciliary neurotrophic factor (CNTF) induces reactive gliosis and gfap expression in müller cells

Sarthy, V., Brodjian, S. J. & Smith, S. B., Dec 1 1997, In : Investigative Ophthalmology and Visual Science. 38, 4

Research output: Contribution to journalArticle

3 Scopus citations

Ciliary neurotrophic factor induces glial fibrillary acidic protein in retinal Müller cells through the JAK/STAT signal transduction pathway

Wang, Y., Smith, S. B., Ogilvie, J. M., McCool, D. J. & Sarthy, V., Oct 23 2002, In : Current Eye Research. 24, 4, p. 305-312 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
47 Scopus citations
Open Access
1 Scopus citations

Cutting edge: IRF8 regulates bax transcription in vivo in primary myeloid cells

Yang, J., Hu, X., Zimmerman, M., Torres, C. M., Yang, D., Smith, S. B. & Liu, K., Nov 1 2011, In : Journal of Immunology. 187, 9, p. 4426-4430 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cystathionine beta synthase expression in mouse retina

Markand, S., Tawfik, A., Ha, Y., Gnana-Prakasam, J., Sonne, S., Ganapathy, V., Sen, N., Xian, M. & Smith, S. B., May 1 2013, In : Current Eye Research. 38, 5, p. 597-604 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Death of retinal neurons in streptozotocin-induced diabetic mice

Martin, P. M., Roon, P., Van Ells, T. K., Ganapathy, V. & Smith, S. B., Sep 1 2004, In : Investigative Ophthalmology and Visual Science. 45, 9, p. 3330-3336 7 p.

Research output: Contribution to journalArticle

325 Scopus citations

Delayed rhodopsin regeneration and altered distribution of interphotoreceptor retinoid binding protein (IRBP) in the mi(vit)/mi(vit) (vitiligo) mouse

Smith, S. B., McClung, J., Wiggert, B. N. & Nir, I., Oct 20 1997, In : Journal of Neurocytology. 26, 9, p. 605-613 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
8 Scopus citations
3 Scopus citations

Detailed electroretinographic findings in rd8 mice

Saul, A. B., Cui, X., Markand, S. & Smith, S. B., Jun 1 2017, In : Documenta Ophthalmologica. 134, 3, p. 195-203 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor

Ha, Y., Saul, A. B., Tawfik, A. M., Zorrilla, E. P., Ganapathy, V. & Smith, S. B., Nov 30 2012, In : Molecular Vision. 18, p. 2860-2870 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Diabetes and Overexpression of proNGF Cause Retinal Neurodegeneration via Activation of RhoA Pathway

Al-Gayyar, M. M. H., Mysona, B. A., Matragoon, S., Abdelsaid, M. A., El-Azab, M. F., Shanab, A. Y., Ha, Y., Smith, S. B., Bollinger, K. E. & El-Remessy, A. B., Jan 30 2013, In : PloS one. 8, 1, e54692.

Research output: Contribution to journalArticle

27 Scopus citations