Tianxiang Hu

Assistant Professor

Biochemistry and Molecular Biology

https://orcid.org/0000-0002-5127-9211

Phone706/721-5257
Emailtihu@augusta.edu

82 Citations
6 h-Index

Research output per year

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Research Output

82 Citations
6 h-Index
13 Article
1 Letter
1 Review article

15 results

2020

Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome

Chong, Y., Liu, Y., Lu, S., Cai, B., Qin, H., Chang, C. S., Ren, M., Cowell, J. K. & Hu, T., Apr 15 2020, In : International Journal of Cancer. 146, 8, p. 2243-2254 12 p.

Research output: Contribution to journal › Article

Rac1/2 activation promotes FGFR1 driven leukemogenesis in stem cell leukemia/lymphoma syndrome

Hu, T., Chong, Y., Lu, S., McGuinness, M., Williams, D. A. & Cowell, J. K., Jan 31 2020, In : Haematologica. 105, 2, p. E68-E71

Research output: Contribution to journal › Letter

Open Access

2019

Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome

Silva, M. J., Chang, C. S., Hu, T., Qin, H., Kitamura, E., Hawthorn, L., Ren, M. & Cowell, J. K., Dec 2019, In : Genomics. 111, 6, p. 1566-1573 8 p.

Research output: Contribution to journal › Article

2 Scopus citations

DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1– driven leukemogenesis

Hu, T., Chong, Y., Cai, B., Liu, Y., Lu, S. & Cowell, J. K., Nov 29 2019, In : Journal of Biological Chemistry. 294, 48, p. 18122-18130 9 p.

Research output: Contribution to journal › Article

1 Scopus citations

Loss of the BCR-FGFR1 GEF domain suppresses RhoA activation and enhances B-lymphomagenesis in mice

Hu, T., Chong, Y., Lu, S., Qin, H., Ren, M., Savage, N. M., Chang, C. S. & Cowell, J. K., Jan 1 2019, In : Cancer Research. 79, 1, p. 114-124 11 p.

Research output: Contribution to journal › Article

3 Scopus citations

2018

FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome

Hu, T., Wu, Q., Chong, Y., Qin, H., Poole, C. J., van Riggelen, J., Ren, M. & Cowell, J. K., Nov 1 2018, In : Leukemia. 32, 11, p. 2363-2373 11 p.

Research output: Contribution to journal › Article

6 Scopus citations

MiR-339 promotes development of stem cell leukemia/lymphoma syndrome via downregulation of the BCL2L11 and BAX proapoptotic genes

Hu, T., Chong, Y., Lu, S., Wang, R., Qin, H., Silva, J., Kitamura, E., Chang, C. S., Hawthorn, L. A. & Cowell, J. K., Jul 1 2018, In : Cancer Research. 78, 13, p. 3522-3531 10 p.

Research output: Contribution to journal › Article

11 Scopus citations

The MIR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase

Hu, T., Chong, Y., Qin, H., Kitamura, E., Chang, C. S., Silva, J., Ren, M. & Cowell, J. K., Apr 1 2018, In : Oncogene. 37, 14, p. 1926-1938 13 p.

Research output: Contribution to journal › Article

9 Scopus citations

2017

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with index of hydroxyurea responsiveness

Zhu, X., Hu, T., Ho, M. H., Wang, Y., Yu, M., Patel, N., Pi, W., Choi, J-H., Xu, H., Ganapathy, V., Kutlar, F., Kutlar, A. & Tuan Lo, D., Nov 30 2017, In : Haematologica. 102, 12, p. 1995-2004 10 p.

Research output: Contribution to journal › Article