• 56 Citations
  • 5 h-Index
20102019
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Research Output 2010 2019

  • 56 Citations
  • 5 h-Index
  • 11 Article
  • 1 Review article
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Article
2019
1 Citation (Scopus)

Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome

Silva, M. J., Chang, C. S., Hu, T., Qin, H., Kitamura, E., Hawthorn, L., Ren, M. & Cowell, J. K., Dec 2019, In : Genomics. 111, 6, p. 1566-1573 8 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Stem Cells
Genes
Stem Cell Niche
1 Citation (Scopus)

Loss of the BCR-FGFR1 GEF domain suppresses RhoA activation and enhances B-lymphomagenesis in mice

Hu, T., Chong, Y., Lu, S., Qin, H., Ren, M., Savage, N. M., Chang, C. S. & Cowell, J. K., Jan 1 2019, In : Cancer Research. 79, 1, p. 114-124 11 p.

Research output: Contribution to journalArticle

Guanidine
Nucleotides
Lymphoma
Leukemia
Stem Cells
2018
1 Citation (Scopus)

FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome

Hu, T., Wu, Q., Chong, Y., Qin, H., Poole, C. J., Van Riggelen, J., Ren, M. & Cowell, J. K., Nov 1 2018, In : Leukemia. 32, 11, p. 2363-2373 11 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Phosphotransferases
Stem Cells
Granzymes
6 Citations (Scopus)

MiR-339 promotes development of stem cell leukemia/lymphoma syndrome via downregulation of the BCL2L11 and BAX proapoptotic genes

Hu, T., Chong, Y., Lu, S., Wang, R., Qin, H., Silva, J., Kitamura, E., Chang, C. S., Hawthorn, L. A. & Cowell, J. K., Jul 1 2018, In : Cancer Research. 78, 13, p. 3522-3531 10 p.

Research output: Contribution to journalArticle

Lymphoma
Leukemia
Stem Cells
Down-Regulation
Cell Survival
6 Citations (Scopus)

The MIR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase

Hu, T., Chong, Y., Qin, H., Kitamura, E., Chang, C. S., Silva, J., Ren, M. & Cowell, J. K., Apr 1 2018, In : Oncogene. 37, 14, p. 1926-1938 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Phosphotransferases
Cell Proliferation
B-Cell Leukemia
Porifera
2017
1 Citation (Scopus)

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with index of hydroxyurea responsiveness

Zhu, X., Hu, T., Ho, M. H., Wang, Y., Yu, M., Patel, N., Pi, W., Choi, J-H., Xu, H., Ganapathy, V., Kutlar, F., Kutlar, A. & Tuan Lo, D., Nov 30 2017, In : Haematologica. 102, 12, p. 1995-2004 10 p.

Research output: Contribution to journalArticle

Erythroblasts
Hydroxyurea
Globins
Sickle Cell Anemia
Genes
5 Citations (Scopus)

Hypermethylated LTR retrotransposon exhibits enhancer activity

Hu, T., Zhu, X., Pi, W., Yu, M., Shi, H. & Tuan Lo, D., Mar 4 2017, In : Epigenetics. 12, 3, p. 226-237 12 p.

Research output: Contribution to journalArticle

Retroelements
Endogenous Retroviruses
Globins
Genes
DNA
6 Citations (Scopus)

Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function

Hu, T., Pi, W., Zhu, X., Yu, M., Ha, H., Shi, H., Choi, J-H. & Tuan Lo, D., Jan 1 2017, In : Nucleic Acids Research. 45, 8, p. 4479-4492 14 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Endogenous Retroviruses
Retroelements
Erythroblasts
Globins
9 Citations (Scopus)
Receptor, Fibroblast Growth Factor, Type 1
Lymphoma
Leukemia
Mutation
Phosphatidylinositol 3-Kinases
2011
4 Citations (Scopus)

Comparative transcriptional analysis reveals differential gene expression between asymmetric and symmetric zygotic divisions in tobacco

Hu, T., Yu, M. & Zhao, J., Nov 1 2011, In : PloS one. 6, 10, e27120.

Research output: Contribution to journalArticle

Tobacco
zygote
Gene expression
Zygote
Asymmetric Cell Division
2010
11 Citations (Scopus)
zygote
transcriptome
tobacco
cells
transcriptomics