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Research Output 1988 2019

2019
2 Citations (Scopus)

Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2

Navneet, S., Zhao, J., Wang, J., Mysona, B. A., Barwick, S., Ammal Kaidery, N., Saul, A. B., Kaddour-Djebbar, I., Bollag, W. B., Thomas, B., Bollinger, K. E. & Smith, S. B., Jun 1 2019, In : Redox Biology. 24, 101199.

Research output: Contribution to journalArticle

Open Access
Hyperhomocysteinemia
Retinal Ganglion Cells
Neuroglia
Antioxidants
Excitatory Amino Acids
1 Citation (Scopus)

Phosphatidylglycerol Inhibits Toll-Like Receptor–Mediated Inflammation by Danger-Associated Molecular Patterns

Choudhary, V., Uaratanawong, R., Patel, R. R., Patel, H., Bao, W., Hartney, B., Cohen, E., Chen, X., Zhong, Q., Isales, C. M. & Bollag, W. B., Apr 2019, In : Journal of Investigative Dermatology. 139, 4, p. 868-877 10 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Psoriasis
Inflammation
Toll-Like Receptors
Skin
2018
5 Citations (Scopus)

Amino acids as signaling molecules modulating bone turnover

Ding, K., Cain, M., Davis, M., Bergson, C. M., McGee Lawrence, M. E., Perkins, C., Hardigan, T., Shi, X. M., Zhong, Q., Xu, J., Bollag, W. B., Hill, W. D., Elsalanty, M. E., Hunter, D. M., Isales, M. C., Lopez, P., Hamrick, M. W. & Isales, C. M., Oct 2018, In : Bone. 115, p. 15-24 10 p.

Research output: Contribution to journalReview article

Bone Remodeling
Amino Acids
Protein-Restricted Diet
Mesenchymal Stromal Cells
Calcium-Sensing Receptors
1 Citation (Scopus)
Osteogenesis
Bone Density
Protein Kinases
Minerals
Bone

Protein kinase D1 conditional null mice show minimal bone loss following ovariectomy

Bollag, W. B., Ding, K., Choudhary, V., Xu, J., Zhong, Q., Elsayed, R., Bailey, L. J., Elsalanty, M. E., Yu, K., Johnson, M. H., McGee Lawrence, M. E. & Isales, C. M., Oct 15 2018, In : Molecular and Cellular Endocrinology. 474, p. 176-183 8 p.

Research output: Contribution to journalArticle

Ovariectomy
Protein Kinases
Bone
Bone and Bones
Knockout Mice
Aquaporin 3
Pharmaceutical Preparations
citraconic acid
2 Citations (Scopus)

Soy phosphatidylglycerol reduces inflammation in a contact irritant ear edema mouse model in vivo

Xie, D., Choudhary, V., Seremwe, M., Edwards, J. G., Wang, A., Emmons, A. C., Bollag, K. A., Johnson, M. H. & Bollag, W. B., Jul 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 366, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Irritants
Ear
Edema
Inflammation
2017
6 Citations (Scopus)
Aquaporin 3
Messenger RNA
Keratinocytes
Pharmaceutical Preparations
Psoriasis
4 Citations (Scopus)

Aquaporins in the skin

Patel, R., Kevin Heard, L., Chen, X. & Bollag, W. B., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 173-191 19 p. (Advances in Experimental Medicine and Biology; vol. 969).

Research output: Chapter in Book/Report/Conference proceedingChapter

Aquaporins
Skin
Langerhans Cells
Water
Fibroblasts
17 Citations (Scopus)

Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

Refaey, M. E., McGee Lawrence, M. E., Fulzele, S. T., Kennedy, E. J., Bollag, W. B., Elsalanty, M. E., Zhong, Q., Ding, K., Bendzunas, N. G., Shi, X. M., Xu, J., Hill, W. D., Johnson, M. H., Hunter, D. M., Pierce, J. L., Yu, K., Hamrick, M. W. & Isales, C. M., Nov 1 2017, In : Journal of Bone and Mineral Research. 32, 11, p. 2182-2193 12 p.

Research output: Contribution to journalArticle

Kynurenine
Tryptophan
Bone and Bones
Aromatic Amino Acids
Anabolic Agents
1 Citation (Scopus)

Possible role of phosphatidylglycerol-activated protein kinase C-βII in keratinocyte differentiation

Bailey, L. J., Choudhary, V. & Bollag, W. B., Oct 1 2017, In : Open Dermatology Journal. 11, p. 59-71 13 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Keratinocytes
Protein Kinase C
Aquaporin 3
Protein Kinases
5 Citations (Scopus)

Regulation of the Glycerol Transporter, Aquaporin-3, by Histone Deacetylase-3 and p53 in Keratinocytes

Choudhary, V., Olala, L. O., Kagha, K., Pan, Z. Q., Chen, X., Yang, R., Cline, A., Helwa, I., Marshall, L., Kaddour-Djebbar, I., McGee-Lawrence, M. E. & Bollag, W. B., Sep 1 2017, In : Journal of Investigative Dermatology. 137, 9, p. 1935-1944 10 p.

Research output: Contribution to journalArticle

Aquaporin 3
Histone Deacetylase Inhibitors
Keratinocytes
Glycerol
Skin Diseases
4 Citations (Scopus)

Very low-density lipoprotein (VLDL)-induced signals mediating aldosterone production

Tsai, Y. Y., Rainey, W. E. & Bollag, W. B., Jan 1 2017, In : Journal of Endocrinology. 232, 2, p. R115-R129

Research output: Contribution to journalReview article

VLDL Lipoproteins
Aldosterone
Hypertension
Obesity
Cytochrome P-450 CYP11B2
2016
1 Citation (Scopus)

A departmental initiative for clinical and translational research

Baer, S., Blake, L., Bollag, W. B., Colombo, R., Diamond, M., George, V., Huber, L., Merchen, L., Yang, F. & Nahman, N. S., Jun 2016, In : Journal of Investigative Medicine. 64, 5, p. 1001-5 5 p.

Research output: Contribution to journalArticle

Translational Medical Research
Research
Financial Support
Studios
Biostatistics
50 Citations (Scopus)

Distinct Nrf2 signaling mechanisms of fumaric acid esters and their role in neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-induced experimental parkinson’s-like disease

Ahuja, M., Kaidery, N. A., Yang, L., Calingasan, N., Smirnova, N., Gaisin, A., Gaisina, I. N., Gazaryan, I., Hushpulian, D. M., Kaddour-Djebbar, I., Bollag, W. B., Morgan, J. C., Ratan, R. R., Starkov, A. A., Beal, M. F. & Thomas, B., Jun 8 2016, In : Journal of Neuroscience. 36, 23, p. 6332-6351 20 p.

Research output: Contribution to journalArticle

NF-E2-Related Factor 2
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Fumarates
Parkinsonian Disorders
Antioxidants

Lipid signaling in keratinocytes: Lipin-1 plays a PArt

Bollag, W. B., Apr 2016, In : Journal of Lipid Research. 57, 4, p. 523-525 3 p.

Research output: Contribution to journalComment/debate

Phosphatidate Phosphatase
Signal transduction
Phosphorylation
Nuclear Proteins
Animals
18 Citations (Scopus)

Obesity, hypertension and aldosterone: Is leptin the link?

Xie, D. & Bollag, W. B., Jan 1 2016, In : Journal of Endocrinology. 230, 1, p. F7-F11

Research output: Contribution to journalReview article

Leptin
Aldosterone
Obesity
Hypertension
VLDL Lipoproteins
3 Citations (Scopus)

Role of phospholipases in adrenal steroidogenesis

Bollag, W. B., Jan 1 2016, In : Journal of Endocrinology. 229, 1, p. R29-R41

Research output: Contribution to journalReview article

Phospholipases
Phospholipase D
Type C Phospholipases
Lipids
Enzymes
1 Citation (Scopus)

The proteolytic effect of bromelain on bullous pemphigoid antigen-2

Belcher, M. D., Kaddour-Djebbar, I., Bollag, W. B. & Davis, L. S., Oct 1 2016, In : Journal of the American Academy of Dermatology. 75, 4, p. 838-840 3 p.

Research output: Contribution to journalArticle

Non-Fibrillar Collagens
Severity of Illness Index
Bromelains
Bullous Pemphigoid
Sampling Studies
4 Citations (Scopus)

VLDL-activated cell signaling pathways that stimulate adrenal cell aldosterone production

Tsai, Y. Y., Rainey, W. E., Johnson, M. H. & Bollag, W. B., Sep 15 2016, In : Molecular and Cellular Endocrinology. 433, p. 138-146 9 p.

Research output: Contribution to journalArticle

Cell signaling
VLDL Lipoproteins
Aldosterone
Hypertension
Obesity
2015
93 Citations (Scopus)

Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis

Huby, A. C., Antonova, G., Groenendyk, J., Gomez-Sanchez, C. E., Bollag, W. B., Filosa, J. A. & Belin de Chantemele, E. J., Dec 1 2015, In : Circulation. 132, 22, p. 2134-2145 12 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Leptin
Aldosterone
Adipocytes
Fibrosis
11 Citations (Scopus)

Aquaporin-3 re-expression induces differentiation in a phospholipase D2-dependent manner in aquaporin-3-knockout mouse keratinocytes

Choudhary, V., Olala, L. O., Qin, H., Helwa, I., Pan, Z. Q., Tsai, Y. Y., Frohman, M. A., Kaddour-Djebbar, I. & Bollag, W. B., Feb 13 2015, In : Journal of Investigative Dermatology. 135, 2, p. 499-507 9 p.

Research output: Contribution to journalArticle

Aquaporin 3
Keratinocytes
Knockout Mice
Glycerol
Differentiation Antigens
2 Citations (Scopus)

Calpain-10 activity underlies angiotensin II-induced aldosterone production in an adrenal glomerulosa cell model

Seremwe, M., Schnellmann, R. G. & Bollag, W. B., Jun 1 2015, In : Endocrinology. 156, 6, p. 2138-2149 12 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Aldosterone
Angiotensin II
Calpain
Cytochrome P-450 CYP11B2
18 Citations (Scopus)

Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets

Jain, A., Samykutty, A., Jackson, C., Browning, D. D., Bollag, W. B., Thangaraju, M., Takahashi, S. & Singh, S. R., Aug 28 2015, In : Cancer Letters. 365, 1, p. 122-131 10 p.

Research output: Contribution to journalArticle

Curcumin
Breast
Epithelial Cells
DNA Repair
Breast Neoplasms
37 Citations (Scopus)

H3K9 trimethylation silences fas expression to confer colon carcinoma immune escape and 5-fluorouracil chemoresistance

Paschall, A. V., Yang, D., Lu, C., Choi, J-H., Li, X., Liu, F., Figueroa, M., Oberlies, N. H., Pearce, C., Bollag, W. B., Nayak, A. & Liu, K., Aug 15 2015, In : Journal of Immunology. 195, 4, p. 1868-1882 15 p.

Research output: Contribution to journalArticle

Fluorouracil
Colon
Carcinoma
Immune Evasion
decitabine

Mechanisms integrating endoplasmic reticulum stress, cholesterol metabolism and steroid hormone biosynthesis in the adrenal cortex

Pan, Z. Q., Zhang, Y. Y., Choudhary, V. & Bollag, W. B., Jan 1 2015, Adrenal Glands: From Pathophysiology to Clinical Evidence. Nova Science Publishers, Inc., p. 19-52 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Endoplasmic Reticulum Stress
Adrenal Cortex
Steroids
Cholesterol
Hormones
20 Citations (Scopus)

Oxidation of the aromatic amino acids tryptophan and tyrosine disrupts their anabolic effects on bone marrow mesenchymal stem cells

El Refaey, M., Watkins, C. P., Kennedy, E. J., Chang, A., Zhong, Q., Ding, K., Shi, X. M., Xu, J., Bollag, W. B., Hill, W. D., Johnson, M. H., Hunter, D. M., Hamrick, M. W. & Isales, C. M., Jul 5 2015, In : Molecular and Cellular Endocrinology. 410, p. 87-96 10 p.

Research output: Contribution to journalReview article

Anabolic Agents
Aromatic Amino Acids
Stem cells
Mesenchymal Stromal Cells
Tryptophan
15 Citations (Scopus)

The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes

Helwa, I., Patel, R., Karempelis, P., Kaddour-Djebbar, I., Choudhary, V. & Bollag, W. B., Jan 1 2015, In : Journal of Pharmacology and Experimental Therapeutics. 352, 1, p. 90-97 8 p., A20.

Research output: Contribution to journalArticle

Keratinocytes
Anti-Inflammatory Agents
Differentiation Antigens
Psoriasis
Keratin-10
2014
10 Citations (Scopus)
Activating Transcription Factors
Cyclic AMP Response Element-Binding Protein
Angiotensin II
Transcription Factors
Messenger RNA
7 Citations (Scopus)

Aromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tension

Refaey, M. E., Zhong, Q., Hill, W. D., Shi, X. M., Hamrick, M. W., Bailey, L., Johnson, M., Xu, J., Bollag, W. B., Chutkan, N. & Isales, C. M., Apr 11 2014, In : PloS one. 9, 4, e91108.

Research output: Contribution to journalArticle

Aromatic Amino Acids
bone marrow cells
Stem cells
Mesenchymal Stromal Cells
aromatic compounds
12 Citations (Scopus)

Distinct effects of different phosphatidylglycerol species on mouse keratinocyte proliferation

Xie, D., Seremwe, M., Edwards, J. G., Podolsky, R. & Bollag, W. B., Sep 18 2014, In : PloS one. 9, 9, e107119.

Research output: Contribution to journalArticle

Phosphatidylglycerols
phosphatidylglycerols
keratinocytes
Keratinocytes
mice
8 Citations (Scopus)

Impact of dietary aromatic amino acids on osteoclastic activity

Refaey, M. E., Zhong, Q., Ding, K., Shi, X. M., Xu, J., Bollag, W. B., Hill, W. D., Chutkan, N., Robbins, R., Nadeau, H., Johnson, M. H., Hamrick, M. W. & Isales, C. M., Jan 1 2014, In : Calcified Tissue International. 95, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

Aromatic Amino Acids
Calcitonin Receptors
Integrin alphaVbeta3
Cathepsin K
Carbonic Anhydrase II

MicroRNAs in the development and progression of skin cancer

Choudhary, V., Gullotto, M., Sato, L. & Bollag, W. B., Jan 1 2014, MicroRNA in Development and in the Progression of Cancer. Springer New York, p. 243-264 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Skin Neoplasms
MicroRNAs
Skin
Neoplasm Metastasis
Messenger RNA
9 Citations (Scopus)

Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: A role in apoptosis in prostate cancer cells

Choudhary, V., Kaddour-Djebbar, I., Alaisami, R., Kumar, M. V. & Bollag, W. B., May 2014, In : International Journal of Oncology. 44, 5, p. 1767-1773 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Homeostasis
Mitochondrial Dynamics
Apoptosis
Calcium
7 Citations (Scopus)

Phospholipase D activity underlies very-low-density lipoprotein (VLDL)-induced aldosterone production in adrenal glomerulosa cells

Tsai, Y. Y., Rainey, W. E., Pan, Z. Q., Frohman, M. A., Choudhary, V. & Bollag, W. B., Sep 1 2014, In : Endocrinology. 155, 9, p. 3550-3560 11 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
VLDL Lipoproteins
Aldosterone
Cytochrome P-450 CYP11B2
4 Citations (Scopus)

Pine oil effects on chemical and thermal injury in mice and cultured mouse dorsal root ganglion neurons

Clark, S. P., Bollag, W. B., Westlund, K. N., Ma, F., Falls, G., Xie, D., Johnson, M. H., Isales, C. M. & Bhattacharyya, M. H., Feb 1 2014, In : Phytotherapy Research. 28, 2, p. 252-260 9 p.

Research output: Contribution to journalArticle

Spinal Ganglia
Oils
Burns
Hot Temperature
Neurons
1 Citation (Scopus)
Phospholipase D
Keratinocytes
Skin
Epidermis
Permeability
5 Citations (Scopus)

Preparation of primary cultures of mouse epidermal keratinocytes and the measurement of phospholipase D activity

Bailey, L. J., Choudhary, V., Merai, P. & Bollag, W. B., 2014, Epidermal Cells: Methods and Protocols. Humana Press Inc., p. 111-131 21 p. (Methods in Molecular Biology; vol. 1195).

Research output: Chapter in Book/Report/Conference proceedingChapter

Phospholipase D
Keratinocytes
Skin
Epidermis
Permeability
6 Citations (Scopus)

Protein kinase C and Src family kinases mediate angiotensin II-induced protein kinase D activation and acute aldosterone production

Olala, L. O., Shapiro, B. A., Merchen, T. D., Wynn, J. J. & Bollag, W. B., Jul 5 2014, In : Molecular and Cellular Endocrinology. 392, 1-2, p. 173-181 9 p.

Research output: Contribution to journalArticle

src-Family Kinases
Aldosterone
Angiotensin II
Protein Kinase C
Chemical activation
2 Citations (Scopus)

Protein kinase D1 deficiency promotes differentiation in epidermal keratinocytes

Choudhary, V., Olala, L. O., Kaddour-Djebbar, I., Helwa, I. & Bollag, W. B., Dec 1 2014, In : Journal of Dermatological Science. 76, 3, p. 186-195 10 p.

Research output: Contribution to journalArticle

Keratinocytes
Protein Kinases
Transglutaminases
Differentiation Antigens
Adenoviridae
61 Citations (Scopus)

Regulation of aldosterone synthesis and secretion

Bollag, W. B., Jan 1 2014, In : Comprehensive Physiology. 4, 3, p. 1017-1055 39 p.

Research output: Contribution to journalArticle

Aldosterone
Zona Glomerulosa
Adrenal Cortex
Hypertension
Kidney
12 Citations (Scopus)

The effect of pioglitazone on aldosterone and cortisol production in HAC15 human adrenocortical carcinoma cells

Pan, Z. Q., Xie, D., Choudhary, V., Seremwe, M., Tsai, Y. Y., Olala, L., Chen, X. & Bollag, W. B., Aug 25 2014, In : Molecular and Cellular Endocrinology. 394, 1-2, p. 119-128 10 p.

Research output: Contribution to journalArticle

pioglitazone
Adrenocortical Carcinoma
Aldosterone
Hydrocortisone
Cells
2013
11 Citations (Scopus)

A role for phospholipase D in angiotensin II-induced protein kinase D activation in adrenal glomerulosa cell models

Olala, L. O., Seremwe, M., Tsai, Y. Y. & Bollag, W. B., Feb 5 2013, In : Molecular and Cellular Endocrinology. 366, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Angiotensin II
Chemical activation
Aldosterone
15 Citations (Scopus)

Cell wounding activates phospholipase D in primary mouse keratinocytes

Arun, S. N., Xie, D., Howard, A. C., Zhong, Q., Zhong, X., McNeil, P. L. & Bollag, W. B., Mar 1 2013, In : Journal of Lipid Research. 54, 3, p. 581-591 11 p.

Research output: Contribution to journalArticle

Phospholipase D
Keratinocytes
Phosphatidylglycerols
Membranes
Aquaporin 3
1 Citation (Scopus)
COUP Transcription Factors
Sphingolipids
Biosynthesis
Epidermis
Permeability
13 Citations (Scopus)

CXCR4 in epidermal keratinocytes: Crosstalk within the skin

Bollag, W. B. & Hill, W. D., Jan 1 2013, In : Journal of Investigative Dermatology. 133, 11, p. 2505-2508 4 p.

Research output: Contribution to journalComment/debate

Crosstalk
Keratinocytes
Skin
Interleukin-23
Basal Cell Carcinoma
2 Citations (Scopus)

GRowing an epidermal tumor

Bollag, W. B. & Isales, C. M., Dec 2013, In : Journal of Investigative Dermatology. 133, 12, p. 2659-2662 4 p.

Research output: Contribution to journalComment/debate

Glucocorticoid Receptors
Tumors
Skin
Physiological Phenomena
Neoplasms
3 Citations (Scopus)

Keratinocytes in psoriasis: Key players in the disease process

Helwa, I., Gullotto, M. & Bollag, W. B., Mar 1 2013, Psoriasis: Types, Triggers and Treatment Strategies. Nova Science Publishers, Inc., p. 1-54 54 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Keratinocytes
Psoriasis
Nail Diseases
Joint Diseases
Immune System Diseases
14 Citations (Scopus)

Lessons from the gene expression pattern of the rat zona glomerulosa

Nishimoto, K., Rainey, W. E., Bollag, W. B. & Seki, T., May 22 2013, In : Molecular and Cellular Endocrinology. 371, 1-2, p. 107-113 7 p.

Research output: Contribution to journalReview article

Zona Glomerulosa
Aldosterone
Gene expression
Rats
Genes
10 Citations (Scopus)
Aquaporin 3
Phosphatidylglycerols
aquaporins
phosphatidylglycerols
keratinocytes