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Research Output 1988 2019

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Article
2019
1 Citation (Scopus)

Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2

Navneet, S., Zhao, J., Wang, J., Mysona, B. A., Barwick, S., Ammal Kaidery, N., Saul, A. B., Kaddour-Djebbar, I., Bollag, W. B., Thomas, B., Bollinger, K. E. & Smith, S. B., Jun 1 2019, In : Redox Biology. 24, 101199.

Research output: Contribution to journalArticle

Open Access
Hyperhomocysteinemia
Retinal Ganglion Cells
Neuroglia
Antioxidants
Excitatory Amino Acids
1 Citation (Scopus)

Phosphatidylglycerol Inhibits Toll-Like Receptor–Mediated Inflammation by Danger-Associated Molecular Patterns

Choudhary, V., Uaratanawong, R., Patel, R. R., Patel, H., Bao, W., Hartney, B., Cohen, E., Chen, X., Zhong, Q., Isales, C. M. & Bollag, W. B., Apr 2019, In : Journal of Investigative Dermatology. 139, 4, p. 868-877 10 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Psoriasis
Inflammation
Toll-Like Receptors
Skin
2018
1 Citation (Scopus)
Osteogenesis
Bone Density
Protein Kinases
Minerals
Bone

Protein kinase D1 conditional null mice show minimal bone loss following ovariectomy

Bollag, W. B., Ding, K., Choudhary, V., Xu, J., Zhong, Q., Elsayed, R., Bailey, L. J., Elsalanty, M. E., Yu, K., Johnson, M. H., McGee Lawrence, M. E. & Isales, C. M., Oct 15 2018, In : Molecular and Cellular Endocrinology. 474, p. 176-183 8 p.

Research output: Contribution to journalArticle

Ovariectomy
Protein Kinases
Bone
Bone and Bones
Knockout Mice
2 Citations (Scopus)

Soy phosphatidylglycerol reduces inflammation in a contact irritant ear edema mouse model in vivo

Xie, D., Choudhary, V., Seremwe, M., Edwards, J. G., Wang, A., Emmons, A. C., Bollag, K. A., Johnson, M. H. & Bollag, W. B., Jul 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 366, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Irritants
Ear
Edema
Inflammation
2017
6 Citations (Scopus)
Aquaporin 3
Messenger RNA
Keratinocytes
Pharmaceutical Preparations
Psoriasis
14 Citations (Scopus)

Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

Refaey, M. E., McGee Lawrence, M. E., Fulzele, S. T., Kennedy, E. J., Bollag, W. B., Elsalanty, M. E., Zhong, Q., Ding, K., Bendzunas, N. G., Shi, X. M., Xu, J., Hill, W. D., Johnson, M. H., Hunter, D. M., Pierce, J. L., Yu, K., Hamrick, M. W. & Isales, C. M., Nov 1 2017, In : Journal of Bone and Mineral Research. 32, 11, p. 2182-2193 12 p.

Research output: Contribution to journalArticle

Kynurenine
Tryptophan
Bone and Bones
Aromatic Amino Acids
Anabolic Agents
1 Citation (Scopus)

Possible role of phosphatidylglycerol-activated protein kinase C-βII in keratinocyte differentiation

Bailey, L. J., Choudhary, V. & Bollag, W. B., Oct 1 2017, In : Open Dermatology Journal. 11, p. 59-71 13 p.

Research output: Contribution to journalArticle

Phosphatidylglycerols
Keratinocytes
Protein Kinase C
Aquaporin 3
Protein Kinases
4 Citations (Scopus)

Regulation of the Glycerol Transporter, Aquaporin-3, by Histone Deacetylase-3 and p53 in Keratinocytes

Choudhary, V., Olala, L. O., Kagha, K., Pan, Z. Q., Chen, X., Yang, R., Cline, A., Helwa, I., Marshall, L., Kaddour-Djebbar, I., McGee-Lawrence, M. E. & Bollag, W. B., Sep 1 2017, In : Journal of Investigative Dermatology. 137, 9, p. 1935-1944 10 p.

Research output: Contribution to journalArticle

Aquaporin 3
Histone Deacetylase Inhibitors
Keratinocytes
Glycerol
Skin Diseases
2016
1 Citation (Scopus)

A departmental initiative for clinical and translational research

Baer, S., Blake, L., Bollag, W. B., Colombo, R., Diamond, M., George, V., Huber, L., Merchen, L., Yang, F. & Nahman, N. S., Jun 2016, In : Journal of Investigative Medicine. 64, 5, p. 1001-5 5 p.

Research output: Contribution to journalArticle

Translational Medical Research
Research
Financial Support
Studios
Biostatistics
50 Citations (Scopus)

Distinct Nrf2 signaling mechanisms of fumaric acid esters and their role in neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-induced experimental parkinson’s-like disease

Ahuja, M., Kaidery, N. A., Yang, L., Calingasan, N., Smirnova, N., Gaisin, A., Gaisina, I. N., Gazaryan, I., Hushpulian, D. M., Kaddour-Djebbar, I., Bollag, W. B., Morgan, J. C., Ratan, R. R., Starkov, A. A., Beal, M. F. & Thomas, B., Jun 8 2016, In : Journal of Neuroscience. 36, 23, p. 6332-6351 20 p.

Research output: Contribution to journalArticle

NF-E2-Related Factor 2
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Fumarates
Parkinsonian Disorders
Antioxidants
1 Citation (Scopus)

The proteolytic effect of bromelain on bullous pemphigoid antigen-2

Belcher, M. D., Kaddour-Djebbar, I., Bollag, W. B. & Davis, L. S., Oct 1 2016, In : Journal of the American Academy of Dermatology. 75, 4, p. 838-840 3 p.

Research output: Contribution to journalArticle

Non-Fibrillar Collagens
Severity of Illness Index
Bromelains
Bullous Pemphigoid
Sampling Studies
4 Citations (Scopus)

VLDL-activated cell signaling pathways that stimulate adrenal cell aldosterone production

Tsai, Y. Y., Rainey, W. E., Johnson, M. H. & Bollag, W. B., Sep 15 2016, In : Molecular and Cellular Endocrinology. 433, p. 138-146 9 p.

Research output: Contribution to journalArticle

Cell signaling
VLDL Lipoproteins
Aldosterone
Hypertension
Obesity
2015
90 Citations (Scopus)

Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis

Huby, A. C., Antonova, G., Groenendyk, J., Gomez-Sanchez, C. E., Bollag, W. B., Filosa, J. A. & Belin de Chantemele, E. J., Dec 1 2015, In : Circulation. 132, 22, p. 2134-2145 12 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Leptin
Aldosterone
Adipocytes
Fibrosis
11 Citations (Scopus)

Aquaporin-3 re-expression induces differentiation in a phospholipase D2-dependent manner in aquaporin-3-knockout mouse keratinocytes

Choudhary, V., Olala, L. O., Qin, H., Helwa, I., Pan, Z. Q., Tsai, Y. Y., Frohman, M. A., Kaddour-Djebbar, I. & Bollag, W. B., Feb 13 2015, In : Journal of Investigative Dermatology. 135, 2, p. 499-507 9 p.

Research output: Contribution to journalArticle

Aquaporin 3
Keratinocytes
Knockout Mice
Glycerol
Differentiation Antigens
1 Citation (Scopus)

Calpain-10 activity underlies angiotensin II-induced aldosterone production in an adrenal glomerulosa cell model

Seremwe, M., Schnellmann, R. G. & Bollag, W. B., Jun 1 2015, In : Endocrinology. 156, 6, p. 2138-2149 12 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Aldosterone
Angiotensin II
Calpain
Cytochrome P-450 CYP11B2
18 Citations (Scopus)

Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets

Jain, A., Samykutty, A., Jackson, C., Browning, D. D., Bollag, W. B., Thangaraju, M., Takahashi, S. & Singh, S. R., Aug 28 2015, In : Cancer Letters. 365, 1, p. 122-131 10 p.

Research output: Contribution to journalArticle

Curcumin
Breast
Epithelial Cells
DNA Repair
Breast Neoplasms
37 Citations (Scopus)

H3K9 trimethylation silences fas expression to confer colon carcinoma immune escape and 5-fluorouracil chemoresistance

Paschall, A. V., Yang, D., Lu, C., Choi, J-H., Li, X., Liu, F., Figueroa, M., Oberlies, N. H., Pearce, C., Bollag, W. B., Nayak, A. & Liu, K., Aug 15 2015, In : Journal of Immunology. 195, 4, p. 1868-1882 15 p.

Research output: Contribution to journalArticle

Fluorouracil
Colon
Carcinoma
Immune Evasion
decitabine
15 Citations (Scopus)

The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes

Helwa, I., Patel, R., Karempelis, P., Kaddour-Djebbar, I., Choudhary, V. & Bollag, W. B., Jan 1 2015, In : Journal of Pharmacology and Experimental Therapeutics. 352, 1, p. 90-97 8 p., A20.

Research output: Contribution to journalArticle

Keratinocytes
Anti-Inflammatory Agents
Differentiation Antigens
Psoriasis
Keratin-10
2014
10 Citations (Scopus)
Activating Transcription Factors
Cyclic AMP Response Element-Binding Protein
Angiotensin II
Transcription Factors
Messenger RNA
6 Citations (Scopus)

Aromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tension

Refaey, M. E., Zhong, Q., Hill, W. D., Shi, X. M., Hamrick, M. W., Bailey, L., Johnson, M., Xu, J., Bollag, W. B., Chutkan, N. & Isales, C. M., Apr 11 2014, In : PloS one. 9, 4, e91108.

Research output: Contribution to journalArticle

Aromatic Amino Acids
bone marrow cells
Stem cells
Mesenchymal Stromal Cells
aromatic compounds
12 Citations (Scopus)

Distinct effects of different phosphatidylglycerol species on mouse keratinocyte proliferation

Xie, D., Seremwe, M., Edwards, J. G., Podolsky, R. & Bollag, W. B., Sep 18 2014, In : PloS one. 9, 9, e107119.

Research output: Contribution to journalArticle

Phosphatidylglycerols
phosphatidylglycerols
keratinocytes
Keratinocytes
mice
7 Citations (Scopus)

Impact of dietary aromatic amino acids on osteoclastic activity

Refaey, M. E., Zhong, Q., Ding, K., Shi, X. M., Xu, J., Bollag, W. B., Hill, W. D., Chutkan, N., Robbins, R., Nadeau, H., Johnson, M. H., Hamrick, M. W. & Isales, C. M., Jan 1 2014, In : Calcified Tissue International. 95, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

Aromatic Amino Acids
Calcitonin Receptors
Integrin alphaVbeta3
Cathepsin K
Carbonic Anhydrase II
9 Citations (Scopus)

Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: A role in apoptosis in prostate cancer cells

Choudhary, V., Kaddour-Djebbar, I., Alaisami, R., Kumar, M. V. & Bollag, W. B., May 2014, In : International Journal of Oncology. 44, 5, p. 1767-1773 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Homeostasis
Mitochondrial Dynamics
Apoptosis
Calcium
7 Citations (Scopus)

Phospholipase D activity underlies very-low-density lipoprotein (VLDL)-induced aldosterone production in adrenal glomerulosa cells

Tsai, Y. Y., Rainey, W. E., Pan, Z. Q., Frohman, M. A., Choudhary, V. & Bollag, W. B., Sep 1 2014, In : Endocrinology. 155, 9, p. 3550-3560 11 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
VLDL Lipoproteins
Aldosterone
Cytochrome P-450 CYP11B2
4 Citations (Scopus)

Pine oil effects on chemical and thermal injury in mice and cultured mouse dorsal root ganglion neurons

Clark, S. P., Bollag, W. B., Westlund, K. N., Ma, F., Falls, G., Xie, D., Johnson, M. H., Isales, C. M. & Bhattacharyya, M. H., Feb 1 2014, In : Phytotherapy Research. 28, 2, p. 252-260 9 p.

Research output: Contribution to journalArticle

Spinal Ganglia
Oils
Burns
Hot Temperature
Neurons
1 Citation (Scopus)
Phospholipase D
Keratinocytes
Skin
Epidermis
Permeability
6 Citations (Scopus)

Protein kinase C and Src family kinases mediate angiotensin II-induced protein kinase D activation and acute aldosterone production

Olala, L. O., Shapiro, B. A., Merchen, T. D., Wynn, J. J. & Bollag, W. B., Jul 5 2014, In : Molecular and Cellular Endocrinology. 392, 1-2, p. 173-181 9 p.

Research output: Contribution to journalArticle

src-Family Kinases
Aldosterone
Angiotensin II
Protein Kinase C
Chemical activation
2 Citations (Scopus)

Protein kinase D1 deficiency promotes differentiation in epidermal keratinocytes

Choudhary, V., Olala, L. O., Kaddour-Djebbar, I., Helwa, I. & Bollag, W. B., Dec 1 2014, In : Journal of Dermatological Science. 76, 3, p. 186-195 10 p.

Research output: Contribution to journalArticle

Keratinocytes
Protein Kinases
Transglutaminases
Differentiation Antigens
Adenoviridae
59 Citations (Scopus)

Regulation of aldosterone synthesis and secretion

Bollag, W. B., Jan 1 2014, In : Comprehensive Physiology. 4, 3, p. 1017-1055 39 p.

Research output: Contribution to journalArticle

Aldosterone
Zona Glomerulosa
Adrenal Cortex
Hypertension
Kidney
11 Citations (Scopus)

The effect of pioglitazone on aldosterone and cortisol production in HAC15 human adrenocortical carcinoma cells

Pan, Z. Q., Xie, D., Choudhary, V., Seremwe, M., Tsai, Y. Y., Olala, L., Chen, X. & Bollag, W. B., Aug 25 2014, In : Molecular and Cellular Endocrinology. 394, 1-2, p. 119-128 10 p.

Research output: Contribution to journalArticle

pioglitazone
Adrenocortical Carcinoma
Aldosterone
Hydrocortisone
Cells
2013
11 Citations (Scopus)

A role for phospholipase D in angiotensin II-induced protein kinase D activation in adrenal glomerulosa cell models

Olala, L. O., Seremwe, M., Tsai, Y. Y. & Bollag, W. B., Feb 5 2013, In : Molecular and Cellular Endocrinology. 366, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Angiotensin II
Chemical activation
Aldosterone
14 Citations (Scopus)

Cell wounding activates phospholipase D in primary mouse keratinocytes

Arun, S. N., Xie, D., Howard, A. C., Zhong, Q., Zhong, X., McNeil, P. L. & Bollag, W. B., Mar 1 2013, In : Journal of Lipid Research. 54, 3, p. 581-591 11 p.

Research output: Contribution to journalArticle

Phospholipase D
Keratinocytes
Phosphatidylglycerols
Membranes
Aquaporin 3
10 Citations (Scopus)
Aquaporin 3
Phosphatidylglycerols
aquaporins
phosphatidylglycerols
keratinocytes
2012
21 Citations (Scopus)

Adrenal cell aldosterone production is stimulated by Very-Low-Density Lipoprotein (VLDL)

Xing, Y., Rainey, W. E., Apolzan, J. W., Francone, O. L., Harris, R. B. S. & Bollag, W. B., Feb 1 2012, In : Endocrinology. 153, 2, p. 721-731 11 p.

Research output: Contribution to journalArticle

VLDL Lipoproteins
Aldosterone
Cytochrome P-450 CYP11B2
Adrenal Glands
Lipoproteins
6 Citations (Scopus)

Diltiazem enhances the apoptotic effects of proteasome inhibitors to induce prostate cancer cell death

Kaddour-Djebbar, I., Choudhary, V., Lakshmikanthan, V., Shirley, R., El Gaish, M., Al-Shabrawey, M., Al-Husein, B., Zhong, R., Davis, M., Dong, Z., Bollag, W. B. & Kumar, M. V., Jun 1 2012, In : Journal of Pharmacology and Experimental Therapeutics. 341, 3, p. 646-655 10 p.

Research output: Contribution to journalArticle

Proteasome Inhibitors
Diltiazem
Prostatic Neoplasms
Cell Death
Apoptosis
2011
36 Citations (Scopus)

Abnormal aquaporin-3 protein expression in hyperproliferative skin disorders

Voss, K. E., Bollag, R. J., Fussell, N., By, C., Sheehan, D. J. & Bollag, W. B., Oct 1 2011, In : Archives of Dermatological Research. 303, 8, p. 591-600 10 p.

Research output: Contribution to journalArticle

Aquaporin 3
Skin
Psoriasis
Skin Neoplasms
Squamous Cell Carcinoma
25 Citations (Scopus)

Novel role of androgens in mitochondrial fission and apoptosis

Choudhary, V., Kaddour-Djebbar, I., Lakshmikanthan, V., Ghazaly, T., Thangjam, G. S., Sreekumar, A., Lewis, R. W., Mills, I. G., Bollag, W. B. & Kumar, M. V., Aug 1 2011, In : Molecular Cancer Research. 9, 8, p. 1067-1077 11 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Dynamins
Androgens
Apoptosis
Proteins
16 Citations (Scopus)

Ultraviolet B irradiation and activation of protein kinase D in primary mouse epidermal keratinocytes

Arun, S. N., Kaddour-Djebbar, I., Shapiro, B. A. & Bollag, W. B., Mar 31 2011, In : Oncogene. 30, 13, p. 1586-1596 11 p.

Research output: Contribution to journalArticle

Keratinocytes
Basal Cell Carcinoma
src-Family Kinases
Apoptosis
Protein Kinase C
30 Citations (Scopus)

Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3

Liu, F., Liu, Q., Yang, D., Bollag, W. B., Robertson, K., Wu, P. & Liu, K., Nov 1 2011, In : Cancer Research. 71, 21, p. 6807-6816 10 p.

Research output: Contribution to journalArticle

DNA Methylation
Colon
Up-Regulation
Apoptosis
Carcinoma
2010
17 Citations (Scopus)

Angiotensin II-activated protein kinase D mediates acute aldosterone secretion

Shapiro, B. A., Olala, L., Arun, S. N., Parker, P. M., George, M. V. & Bollag, W. B., Apr 12 2010, In : Molecular and Cellular Endocrinology. 317, 1-2, p. 99-105 7 p.

Research output: Contribution to journalArticle

Aldosterone
Angiotensin II
Adrenocortical Carcinoma
Zona Glomerulosa
protein kinase D
14 Citations (Scopus)

Phospholipase D2 mediates acute aldosterone secretion in response to angiotensin II in adrenal glomerulosa cells

Qin, H., Frohman, M. A. & Bollag, W. B., May 1 2010, In : Endocrinology. 151, 5, p. 2162-2170 9 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Aldosterone
Angiotensin II
Diglycerides
5 Citations (Scopus)

The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors

Arun, S. N., Xie, D., Dodd, M. E., Zhong, X. & Bollag, W. B., Oct 1 2010, In : Journal of Dermatological Science. 60, 1, p. 29-39 11 p.

Research output: Contribution to journalArticle

Protein Kinase Inhibitors
Tumors
Keratinocytes
Tetradecanoylphorbol Acetate
Neoplasms
2009
16 Citations (Scopus)

Lasp1 gene disruption is linked to enhanced cell migration and tumor formation

Zhang, H., Chen, X., Bollag, W. B., Bollag, R. J., Sheehan, D. J. & Chew, C. S., Aug 1 2009, In : Physiological Genomics. 38, 3, p. 372-385 14 p.

Research output: Contribution to journalArticle

Lipoma
Cell Movement
Focal Adhesions
Zyxin
Molecular Motor Proteins
8 Citations (Scopus)

The role of calcium influx pathways in phospholipase D activation in bovine adrenal glomerulosa cells

Qin, H., Kent, P., Isales, C. M., Parker, P. M., Wilson, M. V. & Bollag, W. B., Oct 5 2009, In : Journal of Endocrinology. 202, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Calcium
Angiotensin II
Aldosterone
2008
51 Citations (Scopus)

Impact of glucose-dependent insulinotropic peptide on age-induced bone loss

Ding, K., Shi, X. M., Zhong, Q., Kang, B., Xie, D., Bollag, W. B., Bollag, R. J., Hill, W. D., Washington, W., Mi, Q. S., Insogna, K., Chutkan, N., Hamrick, M. W. & Isales, C. M., Apr 1 2008, In : Journal of Bone and Mineral Research. 23, 4, p. 536-543 8 p.

Research output: Contribution to journalArticle

Gastric Inhibitory Polypeptide
Bone and Bones
Mesenchymal Stromal Cells
Peptide Receptors
Osteoblasts
8 Citations (Scopus)

Phorbol ester increases mitochondrial cholesterol content in NCI H295R cells

Bollag, W. B., Kent, P., White, S., Wilson, M. V., Isales, C. M. & Calle, R. A., Dec 16 2008, In : Molecular and Cellular Endocrinology. 296, 1-2, p. 53-57 5 p.

Research output: Contribution to journalArticle

Phorbol Esters
Cholesterol
Angiotensin II
Protein Kinase C
Atrial Natriuretic Factor
2007
44 Citations (Scopus)

Angiotensin-II acute regulation of rapid response genes in human, bovine, and rat adrenocortical cells

Nogueira, E. F., Vargas, C. A., Otis, M., Gallo-Payet, N., Bollag, W. B. & Rainey, W. E., Nov 1 2007, In : Journal of Molecular Endocrinology. 39, 5-6, p. 365-374 10 p.

Research output: Contribution to journalArticle

Angiotensin II
Genes
Aldosterone
Nuclear Receptor Subfamily 4, Group A, Member 1
Activating Transcription Factor 3
41 Citations (Scopus)
Aquaporin 3
Phosphatidylglycerols
Keratinocytes
Glycerol
Lipids
8 Citations (Scopus)

Characterization and phospholipase D mediation of the angiotensin II priming response in adrenal glomerulosa cells

Bollag, W. B., Kent, P., White, S., Malinova, M., Isales, C. M. & Calle, R. A., Feb 1 2007, In : Endocrinology. 148, 2, p. 585-593 9 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Angiotensin II
Phorbol 12,13-Dibutyrate
Diglycerides