William Andrew Yeudall

Department Chair

  • 2438 Citations
  • 31 h-Index
1986 …2019
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Research Output 1986 2019

  • 2438 Citations
  • 31 h-Index
  • 68 Article
  • 4 Review article
  • 2 Chapter
  • 1 Comment/debate
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Article
2019
1 Citation (Scopus)

Electrospun gelatin–arabinoxylan ferulate composite fibers for diabetic chronic wound dressing application

Aduba, D. C., An, S. S., Selders, G. S., Yeudall, W. A., Bowlin, G. L., Kitten, T. & Yang, H., Jul 24 2019, In : International Journal of Polymeric Materials and Polymeric Biomaterials. 68, 11, p. 660-668 9 p.

Research output: Contribution to journalArticle

Gelatin
Fibers
Composite materials
Nanofibers
Drug delivery

Targeted inactivation of EPS8 using dendrimer-mediated delivery of RNA interference

Yuan, Q., Yeudall, W. A., Lee, E. & Yang, H., Feb 25 2019, In : International Journal of Pharmaceutics. 557, p. 178-181 4 p.

Research output: Contribution to journalArticle

Dendrimers
RNA Interference
Epidermal Growth Factor
Small Interfering RNA
Growth
2018
1 Citation (Scopus)

EPS8 signaling as a therapeutic target in oral cancer

Yeudall, W. A. & Patel, V., Mar 1 2018, In : Oral Diseases. 24, 1-2, p. 128-131 4 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Epidermal Growth Factor Receptor
Drug Therapy
Therapeutics
2017
16 Citations (Scopus)
Dendrimers
Folic Acid
Small Interfering RNA
Tumors
Acids
9 Citations (Scopus)

Synthesis and Application of Injectable Bioorthogonal Dendrimer Hydrogels for Local Drug Delivery

Xu, L., Cooper, R. C., Wang, J., Yeudall, W. A. & Yang, H., Aug 14 2017, In : ACS Biomaterials Science and Engineering. 3, 8, p. 1641-1653 13 p.

Research output: Contribution to journalArticle

Dendrimers
Hydrogels
Drug delivery
Polyethylene glycols
Tumors
2016
12 Citations (Scopus)

DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex

Nakajima, W., Sharma, K., Lee, J. Y., Maxim, N. T., Hicks, M. A., Vu, T. T., Luu, A., Yeudall, W. A., Tanaka, N. & Harada, H., Jan 1 2016, In : Oncotarget. 7, 24, p. 36353-36365 13 p.

Research output: Contribution to journalArticle

Noxae
Phosphorylation
Apoptosis
DNA
Cisplatin
13 Citations (Scopus)

Folic acid-decorated polyamidoamine dendrimer mediates selective uptake and high expression of genes in head and neck cancer cells

Xu, L., Kittrell, S., Yeudall, W. A. & Yang, H., Nov 1 2016, In : Nanomedicine. 11, 22, p. 2959-2973 15 p.

Research output: Contribution to journalArticle

Dendrimers
Head and Neck Neoplasms
Folic Acid
cancer
Genes
2015
20 Citations (Scopus)

Semi-interpenetrating network (Sipn) co-electrospun gelatin/insulin fiber formulation for transbuccal insulin delivery

Xu, L., Sheybani, N., Ren, S., Bowlin, G. L., Yeudall, W. A. & Yang, H., Jan 1 2015, In : Pharmaceutical Research. 32, 1, p. 275-285 11 p.

Research output: Contribution to journalArticle

Interpenetrating polymer networks
Gelatin
Insulin
Fibers
Scaffolds
20 Citations (Scopus)

The effect of photoinitiators on intracellular AKT signaling pathway in tissue engineering application

Xu, L., Sheybani, N., Yeudall, W. A. & Yang, H., Feb 1 2015, In : Biomaterials Science. 3, 2, p. 250-255 6 p.

Research output: Contribution to journalArticle

Tissue Scaffolds
Photopolymerization
Scaffolds (biology)
Eosine Yellowish-(YS)
Free radicals
16 Citations (Scopus)

Yet another function of p53 - The switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: Implications for autophagy inhibition as a therapeutic strategy

Chakradeo, S., Sharma, K., Alhaddad, A., Bakhshwin, D., Le, N., Harada, H., Nakajima, W., Yeudall, W. A., Torti, S. V., Torti, F. M. & Gewirtz, D. A., May 1 2015, In : Molecular Pharmacology. 87, 5, p. 803-814 12 p.

Research output: Contribution to journalArticle

Autophagy
Radiation
Radiation Tolerance
Therapeutics
Non-Small Cell Lung Carcinoma
2014
15 Citations (Scopus)

Click hybridization of immune cells and polyamidoamine dendrimers

Xu, L., Zolotarskaya, O. Y., Yeudall, W. A. & Yang, H., Jan 1 2014, In : Advanced Healthcare Materials. 3, 9, p. 1430-1438 9 p.

Research output: Contribution to journalArticle

Dendrimers
Assays
Confocal microscopy
Macrophages
Cell Engineering
15 Citations (Scopus)

p53: Its mutations and their impact on transcription

Vaughan, C., Pearsall, I., Yeudall, W. A., Deb, S. P. & Deb, S., Jan 1 2014, In : Sub-Cellular Biochemistry. 85, p. 71-90 20 p.

Research output: Contribution to journalArticle

Transcription
Tumor Suppressor Proteins
Mutation
Transcriptional Activation
Neoplasms
2 Citations (Scopus)

p53 mutation in the genesis of metastasis

Yeudall, W. A., Jan 1 2014, In : Subcellular Biochemistry. 85, p. 105-117 13 p.

Research output: Contribution to journalArticle

Tumors
Neoplasm Metastasis
Mutation
Neoplasms
Lymphatic System
2013
20 Citations (Scopus)

Enhanced chemoresistance of squamous carcinoma cells grown in 3D cryogenic electrospun scaffolds

Bulysheva, A. A., Bowlin, G. L., Petrova, S. P. & Yeudall, W. A., Jan 1 2013, In : Biomedical Materials (Bristol). 8, 5, 055009.

Research output: Contribution to journalArticle

Scaffolds
Cryogenics
Tumors
Cells
Cell culture
19 Citations (Scopus)

Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells

Singh, S., Ramamoorthy, M., Vaughan, C., Yeudall, W. A., Deb, S. & Palit Deb, S., Apr 1 2013, In : Cell Death and Differentiation. 20, 4, p. 558-566 9 p.

Research output: Contribution to journalArticle

Transcriptional Silencer Elements
Oncogene Proteins
Transcription Factors
Phosphorylation
Survival
11 Citations (Scopus)

Increased nucleic acid receptor expression in chronic periodontitis

Sahingur, S. E., Xia, X. J., Voth, S. C., Yeudall, W. A. & Gunsolley, J. C., Oct 1 2013, In : Journal of periodontology. 84, 10

Research output: Contribution to journalArticle

Toll-Like Receptor 9
Chronic Periodontitis
Nucleic Acids
Melanoma
Immune System
2012
18 Citations (Scopus)

Allele specific gain-of-function activity of p53 mutants in lung cancer cells

Vaughan, C. A., Frum, R., Pearsall, I., Singh, S., Windle, B., Yeudall, W. A., Deb, S. P. & Deb, S., Nov 9 2012, In : Biochemical and Biophysical Research Communications. 428, 1, p. 6-10 5 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Alleles
Cells
Cell Line
Transcriptional Activation
36 Citations (Scopus)

Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl

Vaughan, C. A., Singh, S., Windle, B., Yeudall, W. A., Frum, R., Grossman, S. R., Deb, S. P. & Deb, S., Dec 1 2012, In : Genes and Cancer. 3, 7-8, p. 491-502 12 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Lung Neoplasms
Up-Regulation
Chromatin Immunoprecipitation
Histones
60 Citations (Scopus)

Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration

Yeudall, W. A., Vaughan, C. A., Miyazaki, H., Ramamoorthy, M., Choi, M. Y., Chapman, C. G., Wang, H., Black, E., Bulysheva, A. A., Deb, S. P., Windle, B. & Deb, S., Feb 8 2012, In : Carcinogenesis. 33, 2, p. 442-451 10 p.

Research output: Contribution to journalArticle

CXC Chemokines
Cell Movement
Up-Regulation
Carcinogenesis
RNA Interference
17 Citations (Scopus)

Low-temperature electrospun silk scaffold for in vitro mucosal modeling

Bulysheva, A. A., Bowlin, G. L., Klingelhutz, A. J. & Yeudall, W. A., Mar 1 2012, In : Journal of Biomedical Materials Research - Part A. 100 A, 3, p. 757-767 11 p.

Research output: Contribution to journalArticle

Silk
Scaffolds
Temperature
Infiltration
Fibroblasts
2011
8 Citations (Scopus)

Human Oncoprotein MDM2 Up-regulates Expression of NF-κB2 Precursor p100 Conferring a Survival Advantage to Lung Cells

Vaughan, C., Mohanraj, L., Singh, S., Dumur, C. I., Ramamoorthy, M., Garrett, C. T., Windle, B., Yeudall, W. A., Deb, S. & Deb, S. P., Oct 1 2011, In : Genes and Cancer. 2, 10, p. 943-955 13 p.

Research output: Contribution to journalArticle

Oncogene Proteins
Up-Regulation
Lung
Survival
Neoplasms
2010
48 Citations (Scopus)

Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery

Yuan, Q., Lee, E., Yeudall, W. A. & Yang, H., Sep 1 2010, In : Oral Oncology. 46, 9, p. 698-704 7 p.

Research output: Contribution to journalArticle

glycyl-glycyl-glycine
Dendrimers
Epidermal Growth Factor
Nanoparticles
Nucleic Acids
34 Citations (Scopus)

EPS8 upregulates FOXM1 expression, enhancing cell growth and motility

Wang, H., Teh, M. T., Ji, Y., Patel, V., Firouzabadian, S., Patel, A. A., Gutkind, J. S. & Yeudall, W. A., Mar 29 2010, In : Carcinogenesis. 31, 6, p. 1132-1141 10 p.

Research output: Contribution to journalArticle

Cell Movement
Up-Regulation
Growth
Aurora Kinase B
Cell Proliferation
64 Citations (Scopus)

PEGylated polyamidoamine dendrimers with bis-aryl hydrazone linkages for enhanced gene delivery

Yuan, Q., Yeudall, W. A. & Yang, H., Aug 9 2010, In : Biomacromolecules. 11, 8, p. 1940-1947 8 p.

Research output: Contribution to journalArticle

Dendrimers
Hydrazones
Genes
Polyethylene glycols
Acetone
12 Citations (Scopus)

Porphyromonas gingivalis ferrous iron transporter FeoB1 influences sensitivity to oxidative stress

Anaya-Bergman, C., He, J., Jones, K., Miyazaki, H., Yeudall, W. A. & Lewis, J. P., Feb 1 2010, In : Infection and Immunity. 78, 2, p. 688-696 9 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Oxidative Stress
Iron
Peroxides
Oxygen
30 Citations (Scopus)

Surface engineering of macrophages with nanoparticles to generate a cell-nanoparticle hybrid vehicle for hypoxia-targeted drug delivery

Holden, C. A., Yuan, Q., Yeudall, W. A., Lebman, D. A. & Yang, H., Apr 27 2010, In : International Journal of Nanomedicine. 5, 1, p. 25-36 12 p.

Research output: Contribution to journalArticle

Hybrid Cells
Macrophages
Hybrid vehicles
Nanoparticles
Pharmaceutical Preparations
16 Citations (Scopus)

VEGF-C contributes to head and neck squamous cell carcinoma growth and motility

Benke, E. M., Ji, Y., Patel, V., Wang, H., Miyazaki, H. & Yeudall, W. A., Apr 1 2010, In : Oral Oncology. 46, 4

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Growth
Cell Movement
Conditioned Culture Medium
Neoplasms
2009
42 Citations (Scopus)

Role for EPS8 in squamous carcinogenesis

Wang, H., Patel, V., Miyazaki, H., Gutkind, J. S. & Yeudall, W. A., Feb 3 2009, In : Carcinogenesis. 30, 1, p. 165-174 10 p.

Research output: Contribution to journalArticle

Carcinogenesis
Metalloproteases
Keratinocytes
Small Interfering RNA
Proto-Oncogene Proteins c-akt
2008
39 Citations (Scopus)

Docking and hydropathic scoring of polysubstituted pyrrole compounds with antitubulin activity

Tripathi, A., Fornabaio, M., Kellogg, G. E., Gupton, J. T., Gewirtz, D. A., Yeudall, W. A., Vega, N. E. & Mooberry, S. L., Mar 1 2008, In : Bioorganic and Medicinal Chemistry. 16, 5, p. 2235-2242 8 p.

Research output: Contribution to journalArticle

Pyrroles
Tubulin
Colchicine
Free energy
Human Activities
63 Citations (Scopus)

Keratin down-regulation in vimentin-positive cancer cells is reversible by vimentin RNA interference, which inhibits growth and motility

Paccione, R. J., Miyazaki, H., Patel, V., Waseem, A., Gutkind, J. S., Zehner, Z. E. & Yeudall, W. A., Oct 22 2008, In : Molecular cancer therapeutics. 7, 9, p. 2894-2903 10 p.

Research output: Contribution to journalArticle

Vimentin
Keratins
RNA Interference
Down-Regulation
Growth
33 Citations (Scopus)

Roles of CXCL8 in squamous cell carcinoma proliferation and migration

Christofakis, E. P., Miyazaki, H., Rubink, D. S. & Yeudall, W. A., Oct 1 2008, In : Oral Oncology. 44, 10, p. 920-926 7 p.

Research output: Contribution to journalArticle

Cell Movement
Squamous Cell Carcinoma
Cell Proliferation
Chemokines
Neoplasms
2007
64 Citations (Scopus)

Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison

Arthur, C. R., Gupton, J. T., Kellogg, G. E., Yeudall, W. A., Cabot, M. C., Newsham, I. F. & Gewirtz, D. A., Oct 1 2007, In : Biochemical Pharmacology. 74, 7, p. 981-991 11 p.

Research output: Contribution to journalArticle

Pyrroles
Polyploidy
Cell Aging
Poisons
Autophagy
167 Citations (Scopus)

Dissecting the Akt/mammalian target of rapamycin signaling network: Emerging results from the head and neck cancer tissue array initiative

Molinolo, A. A., Hewitt, S. M., Amornphimoltham, P., Keelawat, S., Rangdaeng, S., García, A. M., Raimondi, A. R., Jufe, R., Itoiz, M., Gao, Y., Saranath, D., Kaleebi, G. S., Yoo, G. H., Leak, L., Myers, E. M., Shintani, S., Wong, D., Massey, H. D., Yeudall, W. A., Lonardo, F. & 2 others, Ensley, J. & Gutkind, J. S., Sep 1 2007, In : Clinical Cancer Research. 13, 17, p. 4964-4973 10 p.

Research output: Contribution to journalArticle

Sirolimus
Head and Neck Neoplasms
Epidermal Growth Factor Receptor
Phospho-Specific Antibodies
Critical Pathways
2006
73 Citations (Scopus)

Down-regulation of CXCL5 inhibits squamous carcinogenesis

Miyazaki, H., Patel, V., Wang, H., Edmunds, R. K., Gutkind, J. S. & Yeudall, W. A., Apr 15 2006, In : Cancer Research. 66, 8, p. 4279-4284 6 p.

Research output: Contribution to journalArticle

Carcinogenesis
Down-Regulation
Chemokine CXCL5
CXC Chemokines
Conditioned Culture Medium
29 Citations (Scopus)

Growth factor-sensitive molecular targets identified in primary and metastatic head and neck squamous cell carcinoma using microarray analysis

Miyazaki, H., Patel, V., Wang, H., Ensley, J. F., Gutkind, J. S. & Yeudall, W. A., Mar 1 2006, In : Oral Oncology. 42, 3, p. 240-256 17 p.

Research output: Contribution to journalArticle

Microarray Analysis
Intercellular Signaling Peptides and Proteins
Epidermal Growth Factor
Genes
Oligonucleotide Array Sequence Analysis
35 Citations (Scopus)

Role of Porphyromonas gingivalis FeoB2 in metal uptake and oxidative stress protection

He, J., Miyazaki, H., Anaya, C., Yu, F., Yeudall, W. A. & Lewis, J. P., Jul 1 2006, In : Infection and Immunity. 74, 7, p. 4214-4223 10 p.

Research output: Contribution to journalArticle

Porphyromonas gingivalis
Manganese
Oxidative Stress
Metals
Bacteria
2005
37 Citations (Scopus)

Inability of transforming growth factor-β to cause SnoN degradation leads to resistance to transforming growth factor-β-induced growth arrest in esophageal cancer cells

Edmiston, J. S., Yeudall, W. A., Chung, T. D. & Lebman, D. A., Jun 1 2005, In : Cancer Research. 65, 11, p. 4782-4788 7 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Esophageal Neoplasms
Growth
Smad3 Protein
Cell Line
21 Citations (Scopus)

Uncoupling of epidermal growth factor-dependent proliferation and invasion in a model of squamous carcinoma progression

Yeudall, W. A., Miyazaki, H., Ensley, J. F., Cardinali, M., Gutkind, J. S. & Patel, V., Aug 1 2005, In : Oral Oncology. 41, 7, p. 698-708 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Squamous Cell Carcinoma
Matrix Metalloproteinases
Intercellular Signaling Peptides and Proteins
MAP Kinase Kinase 3
2004
9 Citations (Scopus)

Aberrant p53 alters DNA damage checkpoints in response to cisplatin: Downregulation of CDK expression and activity

Wrighton, K. H., Prêle, C. M., Sunters, A. & Yeudall, W. A., Dec 10 2004, In : International Journal of Cancer. 112, 5, p. 760-770 11 p.

Research output: Contribution to journalArticle

Cisplatin
DNA Damage
Down-Regulation
Cyclin A
Apoptosis
59 Citations (Scopus)

Accelerated cell cycle progression in osteoblasts overexpressing the c-Fos proto-oncogene: Induction of cyclin A and enhanced CDK2 activity

Sunters, A., Thomas, D. P., Yeudall, W. A. & Grigoriadis, A. E., Mar 12 2004, In : Journal of Biological Chemistry. 279, 11, p. 9882-9891 10 p.

Research output: Contribution to journalArticle

fos Genes
Cyclin A
Osteoblasts
Cell Cycle
Cells
2002
37 Citations (Scopus)

Laminin-γ2 overexpression in head-and-neck squamous cell carcinoma

Patel, V., Aldridge, K., Ensley, J. F., Odell, E., Boyd, A., Jones, J., Gutkind, S. & Yeudall, W. A., Jun 1 2002, In : International Journal of Cancer. 99, 4, p. 583-588 6 p.

Research output: Contribution to journalArticle

Laminin
RNA
Staining and Labeling
Islet Cell Adenoma
Carcinoma
1999
21 Citations (Scopus)

p53 and cyclin D1 staining patterns of malignant and premalignant oral lesions in age-dependent populations

Castle, J. T., Cardinali, M., Kratochvil, F. J., Abbondanzo, S. L., Kessler, H. P., Auclair, P. L. & Yeudall, W. A., Jan 1 1999, In : Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 88, 3, p. 326-332 7 p.

Research output: Contribution to journalArticle

Cyclin D1
Staining and Labeling
Carcinoma
Population
Mouth Neoplasms
1998
4 Citations (Scopus)

Cellular factors may enable squamous carcinoma cells to overcome TGFβ- mediated repression of CDK2 activity

Lesaca, E. E., Ensley, J. F. & Yeudall, W. A., Jan 1 1998, In : Oral Oncology. 34, 1, p. 52-57 6 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Squamous Cell Carcinoma
Cell Line
Phosphotransferases
Growth
28 Citations (Scopus)

p21 (WAF1/Cip1) retards the growth of human squamous cell carcinomas in vivo

Cardinali, M., Jakus, J., Shah, S., Ensley, J. F., Robbins, K. C. & Yeudall, W. A., May 1 1998, In : Oral Oncology. 34, 3, p. 211-218 8 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Mouth Neoplasms
Growth
Heterografts
Neoplasms
1997
47 Citations (Scopus)

Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck

Patel, V., Jakus, J., Harris, C. M., Ensley, J. F., Robbins, K. C. & Yeudall, W. A., Dec 1 1997, In : International Journal of Cancer. 73, 4, p. 551-555 5 p.

Research output: Contribution to journalArticle

Cyclin G1
Cyclin-Dependent Kinases
Keratinocytes
Neoplasms
Cell Cycle
18 Citations (Scopus)

Carboxyl-terminal domain of p27(Kip1) activates CDC2

Üren, A., Jakus, J., De Mora, J. F., Yeudall, W. A., Santos, E., Gutkind, S. & Heidaran, M. A., Aug 29 1997, In : Journal of Biological Chemistry. 272, 35, p. 21669-21672 4 p.

Research output: Contribution to journalArticle

Phosphotransferases
Phosphorylation
G2 Phase
Threonine
Cell Division
23 Citations (Scopus)

Functional characterization in vivo of mutant p53 molecules derived from squamous cell carcinomas of the head and neck

Cardinali, M., Kratochvil, F. J., Ensley, J. F., Robbins, K. C. & Yeudall, W. A., Feb 1 1997, In : Molecular Carcinogenesis. 18, 2, p. 78-88 11 p.

Research output: Contribution to journalArticle

NIH 3T3 Cells
Neoplasms
Missense Mutation
Phenotype
Carcinoma, squamous cell of head and neck
40 Citations (Scopus)

Functional characterization of p53 molecules expressed in human squamous cell carcinomas of the head and neck

Yeudall, W. A., Jakus, J., Ensley, J. F. & Robbins, K. C., Feb 1 1997, In : Molecular Carcinogenesis. 18, 2, p. 89-96 8 p.

Research output: Contribution to journalArticle

Complementary DNA
Mutation
Missense Mutation
Mutant Proteins
Reporter Genes
1996
86 Citations (Scopus)

Growth inhibitory concentrations of EGF induce p21 (WAF1/Cip1) and alter cell cycle control in squamous carcinoma cells

Jakus, J. & Yeudall, W. A., Jul 5 1996, In : Oncogene. 12, 11, p. 2369-2376 8 p.

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Epidermal Growth Factor
Squamous Cell Carcinoma
Growth
Thymidine
1 Citation (Scopus)

TGF-β isoforms fail to modulate inositol phosphates and cAMP in normal and tumour-derived human oral keratinocytes

Collier, A. J., Elsegood, K. A., Yeudall, W. A., Paterson, I. C., Prime, S. S. & Sandy, J. R., Mar 1 1996, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1315, 2, p. 117-122 6 p.

Research output: Contribution to journalArticle

Inositol Phosphates
Keratinocytes
Protein Isoforms
Neoplasms
Cell Line