• 4324 Citations
  • 28 h-Index
20022019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2019

Body mass index drives changes in DNA methylation: A longitudinal study

Sun, D., Zhang, T., Su, S., Hao, G., Chen, T., Li, Q. Z., Bazzano, L., He, J., Wang, X., Li, S. & Chen, W., Oct 11 2019, In : Circulation research. 125, 9, p. 824-833 10 p.

Research output: Contribution to journalArticle

Open Access

Determinants of pulse wave velocity trajectories from youth to young adulthood: the Georgia Stress and Heart Study

Liang, X., Su, S., Hao, G., Snieder, H., Treiber, F., Kapuku, G. & Wang, X., Mar 1 2019, In : Journal of hypertension. 37, 3, p. 563-571 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Discovery and Validation of a Novel Neutrophil Activation Marker Associated with Obesity

Pan, Y., Choi, J-H., Shi, H., Zhang, L., Su, S. & Wang, X., Dec 1 2019, In : Scientific reports. 9, 1, 3433.

Research output: Contribution to journalArticle

Leisure-time physical activity and DNA methylation age - A twin study

Sillanpää, E., Ollikainen, M., Kaprio, J., Wang, X., Leskinen, T., Kujala, U. M. & Törmäkangas, T., Jan 19 2019, In : Clinical epigenetics. 11, 1, 12.

Research output: Contribution to journalArticle

4 Scopus citations
2018

An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression

Wang, X., Pan, Y., Zhu, H., Hao, G., Huang, Y., Barnes, V., Shi, H., Snieder, H., Pankow, J., North, K., Grove, M., Guan, W., Demerath, E., Dong, Y. & Su, S., Jan 1 2018, In : Clinical epigenetics. 10, 1 p.

Research output: Contribution to journalArticle

4 Scopus citations
8 Scopus citations

Epigenome-Wide Association Study of Dietary Fiber Intake in African American Adolescents

Chen, L., Dong, Y., Wang, X., Hao, G., Huang, Y., Gutin, B. & Zhu, H., Jun 2018, In : Molecular Nutrition and Food Research. 62, 12, 1800155.

Research output: Contribution to journalArticle

1 Scopus citations

Genetic and environmental effects on gene expression signatures of blood pressure: A transcriptome-wide twin study

Huang, Y., Ollikainen, M., Sipil, P., Mustelin, L., Wang, X., Su, S., Huan, T., Levy, D., Wilson, J., Snieder, H., Kaprio, J. & Wang, X., Jan 1 2018, In : Hypertension. 71, 3, p. 457-464 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - A preliminary report

Shiao, S. P. K., Xiao, H., Dong, L., Wang, X., Liu, K., She, J. & Shi, H., May 22 2018, In : Oncotarget. 9, 39, p. 25557-25571 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Heritability and familial aggregation of blood pressure

Wang, X. & Snieder, H., Jan 1 2018, Pediatric Hypertension. Springer International Publishing, p. 159-176 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Assessing genetic risk of hypertension at an early age: future research directions

Wang, X. & Snieder, H., Nov 2 2017, In : Expert Review of Cardiovascular Therapy. 15, 11, p. 809-812 4 p.

Research output: Contribution to journalEditorial

Blood pressure trajectories from childhood to young adulthood associated with cardiovascular risk

Hao, G., Wang, X., Treiber, F. A., Harshfield, G., Kapuku, G. & Su, S., Mar 1 2017, In : Hypertension. 69, 3, p. 435-442 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In : Journal of the American Heart Association. 6, 6, e004918.

Research output: Contribution to journalArticle

32 Scopus citations

Effects of oral α-lipoic acid administration on body weight in overweight or obese subjects: a crossover randomized, double-blind, placebo-controlled trial

Li, N., Yan, W., Hu, X., Huang, Y., Wang, F., Zhang, W., Wang, Q., Wang, X. & Sun, K., May 1 2017, In : Clinical Endocrinology. 86, 5, p. 680-687 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis

Xu, Y., Wang, Y., Yan, S., Zhou, Y., Yang, Q., Pan, Y., Zeng, X., An, X., Liu, Z., Wang, L., Xu, J., Cao, Y., Fulton, D. J., Weintraub, N. L., Bagi, Z., Hoda, MD. N., Wang, X., Li, Q., Hong, M., Jiang, X. & 4 others, Boison, D., Weber, C., Wu, C. & Huo, Y., Sep 2017, In : EMBO Molecular Medicine. 9, 9, p. 1263-1278 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

Racial/ethnic differences in the association of childhood adversities with depression and the role of resilience

Youssef, N. A., Belew, D., Hao, G., Wang, X., Treiber, F. A., Stefanek, M., Yassa, M., Boswell, E., McCall, W. V. & Su, S., Jan 15 2017, In : Journal of Affective Disorders. 208, p. 577-581 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Differential methylation tests of regulatory regions

Ryu, D., Xu, H., George, V., Su, S., Wang, X., Shi, H. & Podolsky, R. H., Jun 1 2016, In : Statistical Applications in Genetics and Molecular Biology. 15, 3, p. 237-251 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B. & 678 others, Nalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Tanaka, T., Reilly, M. P., Schunkert, H., Assimes, T. L., Hall, A., Hengstenberg, C., König, I. R., Laaksonen, R., McPherson, R., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L. A., Halperin, E., Li, M., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G. A., Holm, H., Roberts, R., Stewart, A. F. R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K. J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H. J., Perret, C., Proust, C., Münzel, T. F., Barbalic, M., Chen, I. Y. D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K. D., Volcik, K., Gretarsdottir, S., Gulcher, J. R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A. K., Willenborg, C., Böhm, B. O., Dobnig, H., Grammer, T. B., Hoffmann, M. M., Meinitzer, A., Winkelmann, B. R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S. B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Devaney, J., Burnett, M. S., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Knouff, C. W., Waterworth, D. M., Walker, M. C., Epstein, S. E., Rader, D. J., Nelson, C. P., Wright, B. J., Balmforth, A. J., Ball, S. G., Loehr, L. R., Rosamond, W. D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y. A., Stricker, B. H., Chang, P. P., Willerson, J. T., Felix, S. B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., Jan 21 2016, In : Nature communications. 7, 10023.

Research output: Contribution to journalArticle

180 Scopus citations

Growth of Carotid Intima-Media Thickness in Black and White Young Adults

Hao, G., Wang, X., Treiber, F. A., Davis, H., Leverett, S., Su, S. & Kapuku, G., Dec 2016, In : Journal of the American Heart Association. 5, 12, e004147.

Research output: Contribution to journalArticle

3 Scopus citations

Phenotypic alteration of CD8+ T cells in chronic lymphocytic leukemia is associated with epigenetic reprogramming

Wu, J., Xu, X., Lee, E. J., Shull, A. Y., Pei, L., Awan, F., Wang, X., Choi, J-H., Deng, L., Xin, H. B., Zhong, W., Liang, J., Miao, Y., Wu, Y., Fan, L., Li, J., Xu, W. & Shi, H., Jan 1 2016, In : Oncotarget. 7, 26, p. 40558-40570 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Pulse wave velocity in elastic and muscular arteries: Tracking stability and association with anthropometric and hemodynamic measurements

Ye, C., Pan, Y., Xu, X., Su, S., Snieder, H., Treiber, F., Kapuku, G. & Wang, X., Nov 1 2016, In : Hypertension Research. 39, 11, p. 786-791 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Adverse childhood experiences and blood pressure trajectories from childhood to young adulthood: the Georgia stress and Heart study

Su, S., Wang, X., Pollock, J. S., Treiber, F. A., Xu, X., Snieder, H., McCall, W. V., Stefanek, M. & Harshfield, G. A., May 12 2015, In : Circulation. 131, 19, p. 1674-81 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension

EchoGen consortium, CHARGE-HF consortium, International Consortium for Blood Pressure GWAS (ICBP), CARDIoGRAM consortium, CKDGen Consortium & KidneyGen Consortium, Mar 18 2015, In : PLoS Genetics. 11, 3, e1005035.

Research output: Contribution to journalArticle

58 Scopus citations

Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals

Zhou, H., Lei, X., Benson, T., Mintz, J., Xu, X., Harris, R. B., Weintraub, N. L., Wang, X. & Chen, W., Oct 1 2015, In : Journal of Lipid Research. 56, 10, p. 1912-1925 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring

Küpers, L. K., Xu, X., Jankipersadsing, S. A., Vaez, A., La Bastide-van Gemert, S., Scholtens, S., Nolte, I. M., Richmond, R. C., Relton, C. L., Felix, J. F., Duijts, L., Van Meurs, J. B., Tiemeier, H., Jaddoe, V. W., Wang, X., Corpeleijn, E. & Snieder, H., Aug 2015, In : International Journal of Epidemiology. 44, 4, p. 1224-1237 14 p.

Research output: Contribution to journalArticle

86 Scopus citations

Ethnic differences in resting heart rate variability: A systematic review and meta-analysis

Hill, L. K., Hu, D. D., Koenig, J., Sollers, J. J., Kapuku, G., Wang, X., Snieder, H. & Thayer, J. F., Jan 1 2015, In : Psychosomatic Medicine. 77, 1, p. 16-25 10 p.

Research output: Contribution to journalReview article

62 Scopus citations

Familial aggregation and childhood blood pressure

Wang, X., Xu, X., Su, S. & Snieder, H., Jan 1 2015, In : Current Hypertension Reports. 17, 1, p. 509 1 p.

Research output: Contribution to journalArticle

9 Scopus citations

Obesity is associated with more activated neutrophils in African American male youth

Xu, X., Su, S., Wang, X., Barnes, V., De Miguel, C., Ownby, D., Pollock, J., Snieder, H. & Chen, W., Jan 10 2015, In : International Journal of Obesity. 39, 1, p. 26-32 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Specific genetic influences on nighttime blood pressure

Xu, X., Su, S., Treiber, F. A., Vlietinck, R., Fagard, R., Derom, C., Gielen, M., Loos, R. J. F., Snieder, H. & Wang, X., Apr 1 2015, In : American journal of hypertension. 28, 4, p. 440-443 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

A 2-step penalized regression method for family-based next-generation sequencing association studies

Ding, X., Su, S., Nandakumar, K., Wang, X. & Fardo, D. W., Jun 17 2014, In : BMC Proceedings. 8, S25.

Research output: Contribution to journalArticle

3 Scopus citations

Adverse childhood experiences are associated with detrimental hemodynamics and elevated circulating endothelin-1 in adolescents and young adults

Su, S., Wang, X., Kapuku, G. K., Treiber, F. A., Pollock, D. M., Harshfield, G. A., McCall, W. V. & Pollock, J. S., Jul 2014, In : Hypertension. 64, 1, p. 201-207 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Dietary sodium, adiposity, and inflammation in healthy adolescents

Zhu, H., Pollock, N. K., Kotak, I., Gutin, B., Wang, X., Bhagatwala, J., Parikh, S., Harshfield, G. A. & Dong, Y., Jan 1 2014, In : Pediatrics. 133, 3, p. e635-e642

Research output: Contribution to journalArticle

58 Scopus citations

DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation

Su, S., Zhu, H., Xu, X., Wang, X., Wang, X., Dong, Y., Kapuku, K. G., Treiber, F., Gutin, B., Harshfield, G. A. & Snieder, H., Jun 2014, In : Twin Research and Human Genetics. 17, 3, p. 183-191 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Identifying genetic variants for heart rate variability in the acetylcholine pathway

Riese, H., Muñoz, L. M., Hartman, C. A., Ding, X., Su, S., Oldehinkel, A. J., Van Roon, A. M., Van Der Most, P. J., Lefrt, J., Gansevoort, R. T., Van Der Harst, P., Verweij, N., Licht, C. M. M., Boomsma, D. I., Hottenga, J. J., Willemsen, G., Penninx, B. W. J. H., Nolte, I. M., De Geus, E. J. C., Wang, X. & 1 others, Snieder, H., Nov 10 2014, In : PloS one. 9, 11, e112476.

Research output: Contribution to journalArticle

5 Scopus citations
2013

A genome-wide methylation study of severe vitamin d deficiency in African American adolescents

Zhu, H., Wang, X., Shi, H., Su, S., Harshfield, G. A., Gutin, B., Snieder, H. & Dong, Y., Jan 1 2013, In : Journal of Pediatrics. 162, 5

Research output: Contribution to journalArticle

47 Scopus citations

A Genome-Wide Methylation Study on Essential Hypertension in Young African American Males

Wang, X., Falkner, B., Zhu, H., Shi, H., Su, S., Xu, X., Sharma, A. K., Dong, Y., Treiber, F., Gutin, B., Harshfield, G. & Snieder, H., Jan 17 2013, In : PloS one. 8, 1, e53938.

Research output: Contribution to journalArticle

43 Scopus citations

A genome-wide methylation study on obesity: Differential variability and differential methylation

Xu, X., Su, S., Barnes, V. A., De Miguel, C., Pollock, J., Ownby, D., Shi, H., Zhu, H., Snieder, H. & Wang, X., May 2013, In : Epigenetics. 8, 5, p. 522-533 12 p.

Research output: Contribution to journalArticle

97 Scopus citations

A Method to Detect Differentially Methylated Loci With Next-Generation Sequencing

Xu, H., Podolsky, R. H., Ryu, D., Wang, X., Su, S., Shi, H. & George, V., May 1 2013, In : Genetic Epidemiology. 37, 4, p. 377-382 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: A double-blinded, randomized, controlled, cross-over intervention trial

Yan, W., Li, N., Hu, X., Huang, Y., Zhang, W., Wang, Q., Wang, F., Wang, C., Zhai, X., Xu, R., Yan, K., Ding, X. & Wang, X., Jul 31 2013, In : International Journal of Cardiology. 167, 2, p. 602-603 2 p.

Research output: Contribution to journalArticle

12 Scopus citations

Familial aggregation of blood pressure

Wang, X. & Snieder, H., Jan 1 2013, Pediatric Hypertension: Third Edition. Humana Press Inc., p. 195-209 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Genetic and environmental influences on blood pressure variability: A study in twins

Xu, X., Ding, X., Zhang, X., Su, S., Treiber, F. A., Vlietinck, R., Fagard, R., Derom, C., Gielen, M., Loos, R. J. F., Snieder, H. & Wang, X., Apr 1 2013, In : Journal of hypertension. 31, 4, p. 690-697 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of seven loci affecting mean telomere length and their association with disease

Codd, V., Nelson, C. P., Albrecht, E., Mangino, M., Deelen, J., Buxton, J. L., Hottenga, J. J., Fischer, K., Esko, T., Surakka, I., Broer, L., Nyholt, D. R., Leach, I. M., Salo, P., Hägg, S., Matthews, M. K., Palmen, J., Norata, G. D., O'Reilly, P. F., Saleheen, D. & 79 others, Amin, N., Balmforth, A. J., Beekman, M., De Boer, R. A., Böhringer, S., Braund, P. S., Burton, P. R., Craen, A. J. M., Denniff, M., Dong, Y., Douroudis, K., Dubinina, E., Eriksson, J. G., Garlaschelli, K., Guo, D., Hartikainen, A. L., Henders, A. K., Houwing-Duistermaat, J. J., Kananen, L., Karssen, L. C., Kettunen, J., Klopp, N., Lagou, V., Van Leeuwen, E. M., Madden, P. A., Mägi, R., Magnusson, P. K. E., Männistö, S., McCarthy, M. I., Medland, S. E., Mihailov, E., Montgomery, G. W., Oostra, B. A., Palotie, A., Peters, A., Pollard, H., Pouta, A., Prokopenko, I., Ripatti, S., Salomaa, V., Suchiman, H. E. D., Valdes, A. M., Verweij, N., Viñuela, A., Wang, X., Wichmann, H. E., Widen, E., Willemsen, G., Wright, M. J., Xia, K., Xiao, X., Van Veldhuisen, D. J., Catapano, A. L., Tobin, M. D., Hall, A. S., Blakemore, A. I. F., Van Gilst, W. H., Zhu, H., Erdmann, J., Reilly, M. P., Kathiresan, S., Schunkert, H., Talmud, P. J., Pedersen, N. L., Perola, M., Ouwehand, W., Kaprio, J., Martin, N. G., Van Duijn, C. M., Hovatta, I., Gieger, C., Metspalu, A., Boomsma, D. I., Jarvelin, M. R., Slagboom, P. E., Thompson, J. R., Spector, T. D., Van Der Harst, P. & Samani, N. J., Apr 1 2013, In : Nature Genetics. 45, 4, p. 422-427 6 p.

Research output: Contribution to journalArticle

460 Scopus citations

Reply to manuscript IJC-D-12-04197 entitled "Does alpha-lipoic acid treatment play a role on oxidative stress and insulin resistance in overweight/obese patients?" by MD Turgay Ulas

Yan, W., Li, N., Hu, X., Huang, Y., Zhang, W., Wang, Q., Wang, F., Wang, C., Zhai, X., Xu, R., Yan, K., Ding, X. & Wang, X., Sep 30 2013, In : International Journal of Cardiology. 168, 2, 1 p.

Research output: Contribution to journalArticle

Urinary prostasin excretion is associated with adiposity in nonhypertensive African-American adolescents

Guo, D. H., Parikh, S. J., Chao, J., Pollock, N. K., Wang, X., Snieder, H., Navis, G., Wilson, J. G., Bhagatwala, J., Zhu, H. & Dong, Y., Aug 1 2013, In : Pediatric research. 74, 2, p. 206-210 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Urinary prostasin excretion is associated with adiposity in non-hypertensive African American adolescents

Guo, D-H., Parikh, S., Chao, J., Pollock, N. K., Wang, X., Snieder, H., Navis, G., Bhagatwala, J., Zhu, H. & Dong, Y., 2013, In : Pediatric Research. In Press

Research output: Contribution to journalArticle

2011

[The effect of oral alpha-lipoic acid in overweight/obese individuals on brachial-ankle pulse wave velocity and supine blood pressure: a randomized, crossover, double-blind, placebo-controlled trial].

Huang, Y. D., Li, N., Zhang, W. G., Hu, X. J., Wang, Q., Wang, C. C., Xu, R. W., Yan, K., Hou, X. Y., Naerkeze, Wang, X. & Yan, W. L., Mar 2011, In : Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi. 32, 3, p. 290-296 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Beyond genome-wide association studies: New strategies for identifying genetic determinants of hypertension

Wang, X., Prins, B. P., Sõber, S., Laan, M. & Snieder, H., Dec 1 2011, In : Current Hypertension Reports. 13, 6, p. 442-451 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Genetic and environmental influences on blood pressure and body mass index in Han Chinese: A twin study

Wu, T., Snieder, H., Li, L., Cao, W., Zhan, S., Lv, J., Gao, W., Wang, X., Ding, X. & Hu, Y., Feb 1 2011, In : Hypertension Research. 34, 2, p. 173-179 7 p.

Research output: Contribution to journalArticle

20 Scopus citations