• 4155 Citations
  • 27 h-Index
20022019
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Research Output 2002 2019

Article
1248 Citations (Scopus)

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Ehret, G. B., Munroe, P. B., Rice, K. M., Bochud, M., Johnson, A. D., Chasman, D. I., Smith, A. V., Tobin, M. D., Verwoert, G. C., Hwang, S. J., Pihur, V., Vollenweider, P., O'Reilly, P. F., Amin, N., Bragg-Gresham, J. L., Teumer, A., Glazer, N. L., Launer, L., Zhao, J. H., Aulchenko, Y. & 326 others, Heath, S., Sober, S., Parsa, A., Luan, J., Arora, P., Dehghan, A., Zhang, F., Lucas, G., Hicks, A. A., Jackson, A. U., Peden, J. F., Tanaka, T., Wild, S. H., Rudan, I., Igl, W., Milaneschi, Y., Parker, A. N., Fava, C., Chambers, J. C., Fox, E. R., Kumari, M., Go, M. J., van der Harst, P., Kao, W. H. L., Sjögren, M., Vinay, D. G., Alexander, M., Tabara, Y., Shaw-Hawkins, S., Whincup, P. H., Liu, Y., Shi, G., Kuusisto, J., Tayo, B., Seielstad, M., Sim, X., Hoang Nguyen, K. D., Lehtimäki, T., Matullo, G., Wu, Y., Gaunt, T. R., Charlotte Onland-Moret, N., Cooper, M. N., Platou, C. G. P., Org, E., Hardy, R., Dahgam, S., Palmen, J., Vitart, V., Braund, P. S., Kuznetsova, T., Uiterwaal, C. S. P. M., Adeyemo, A., Palmas, W., Campbell, H., Ludwig, B., Tomaszewski, M., Tzoulaki, I., Palmer, N. D., Aspelund, T., Garcia, M., Chang, Y. P. C., O'Connell, J. R., Steinle, N. I., Grobbee, D. E., Arking, D. E., Kardia, S. L., Morrison, A. C., Hernandez, D., Najjar, S., McArdle, W. L., Hadley, D., Brown, M. J., Connell, J. M., Hingorani, A. D., Day, I. N. M., Lawlor, D. A., Beilby, J. P., Lawrence, R. W., Clarke, R., Hopewell, J. C., Ongen, H., Dreisbach, A. W., Li, Y., Hunter Young, J., Bis, J. C., Kähönen, M., Viikari, J., Adair, L. S., Lee, N. R., Chen, M. H., Olden, M., Pattaro, C., Bolton, J. A. H., Köttgen, A., Bergmann, S., Mooser, V., Chaturvedi, N., Frayling, T. M., Islam, M., Jafar, T. H., Erdmann, J., Kulkarni, S. R., Bornstein, S. R., Grässler, J., Groop, L., Voight, B. F., Kettunen, J., Howard, P., Taylor, A., Guarrera, S., Ricceri, F., Emilsson, V., Plump, A., Barroso, I., Khaw, K. T., Weder, A. B., Hunt, S. C., Sun, Y. V., Bergman, R. N., Collins, F. S., Bonnycastle, L. L., Scott, L. J., Stringham, H. M., Peltonen, L., Perola, M., Vartiainen, E., Brand, S. M., Staessen, J. A., Wang, T. J., Burton, P. R., Artigas, M. S., Dong, Y., Snieder, H., Wang, X., Zhu, H., Lohman, K. K., Rudock, M. E., Heckbert, S. R., Smith, N. L., Wiggins, K. L., Doumatey, A., Shriner, D., Veldre, G., Viigimaa, M., Kinra, S., Prabhakaran, D., Tripathy, V., Langefeld, C. D., Rosengren, A., Thelle, D. S., Corsi, A. M., Singleton, A., Forrester, T., Hilton, G., McKenzie, C. A., Salako, T., Iwai, N., Kita, Y., Ogihara, T., Ohkubo, T., Okamura, T., Ueshima, H., Umemura, S., Eyheramendy, S., Meitinger, T., Wichmann, H. E., Cho, Y. S., Kim, H. L., Lee, J. Y., Scott, J., Sehmi, J. S., Zhang, W., Hedblad, B., Nilsson, P., Smith, G. D., Wong, A., Narisu, N., Stančáková, A., Raffel, L. J., Yao, J., Kathiresan, S., O'Donnell, C. J., Schwartz, S. M., Arfan Ikram, M., Longstreth, W. T., Mosley, T. H., Seshadri, S., Shrine, N. R. G., Wain, L. V., Morken, M. A., Swift, A. J., Laitinen, J., Prokopenko, I., Zitting, P., Cooper, J. A., Humphries, S. E., Danesh, J., Rasheed, A., Goel, A., Hamsten, A., Watkins, H., Bakker, S. J. L., van Gilst, W. H., Janipalli, C. S., Radha Mani, K., Yajnik, C. S., Hofman, A., Mattace-Raso, F. U. S., Oostra, B. A., Demirkan, A., Isaacs, A., Rivadeneira, F., Lakatta, E. G., Orru, M., Scuteri, A., Ala-Korpela, M., Kangas, A. J., Lyytikäinen, L. P., Soininen, P., Tukiainen, T., Würtz, P., Twee-HeeOng, R., Dörr, M., Kroemer, H. K., Völker, U., Völzke, H., Galan, P., Hercberg, S., Lathrop, M., Zelenika, D., Deloukas, P., Mangino, M., Spector, T. D., Zhai, G., Meschia, J. F., Nalls, M. A., Sharma, P., Terzic, J., Kranthi Kumar, M. V., Denniff, M., Zukowska-Szczechowska, E., Wagenknecht, L. E., Fowkes, F. G. R., Charchar, F. J., Schwarz, P. E. H., Hayward, C., Guo, X., Rotimi, C., Bots, M. L., Brand, E., Samani, N. J., Polasek, O., Talmud, P. J., Nyberg, F., Kuh, D., Laan, M., Hveem, K., Palmer, L. J., van der Schouw, Y. T., Casas, J. P., Mohlke, K. L., Vineis, P., Raitakari, O., Ganesh, S. K., Wong, T. Y., Shyong Tai, E., Cooper, R. S., Laakso, M., Rao, D. C., Harris, T. B., Morris, R. W., Dominiczak, A. F., Kivimaki, M., Marmot, M. G., Miki, T., Saleheen, D., Chandak, G. R., Coresh, J., Navis, G., Salomaa, V., Han, B. G., Zhu, X., Kooner, J. S., Melander, O., Ridker, P. M., Bandinelli, S., Gyllensten, U. B., Wright, A. F., Wilson, J. F., Ferrucci, L., Farrall, M., Tuomilehto, J., Pramstaller, P. P., Elosua, R., Soranzo, N., Sijbrands, E. J. G., Altshuler, D., Loos, R. J. F., Shuldiner, A. R., Gieger, C., Meneton, P., Uitterlinden, A. G., Wareham, N. J., Gudnason, V., Rotter, J. I., Rettig, R., Uda, M., Strachan, D. P., Witteman, J. C. M., Hartikainen, A. L., Beckmann, J. S., Boerwinkle, E., Vasan, R. S., Boehnke, M., Larson, M. G., Järvelin, M. R., Psaty, B. M., Abecasis, G. R., Chakravarti, A., Elliott, P., van Duijn, C. M., Newton-Cheh, C., Levy, D., Caulfield, M. J. & Johnson, T., Oct 6 2011, In : Nature. 478, 7367, p. 103-109 7 p.

Research output: Contribution to journalArticle

Hematologic Diseases
Cardiovascular Diseases
Blood Pressure
Blood Physiological Phenomena
Furin
1 Citation (Scopus)
DNA Methylation
Methylation
Colorectal Neoplasms
Genome
Neoplasm Genes
2 Citations (Scopus)

Growth of Carotid Intima-Media Thickness in Black and White Young Adults

Hao, G., Wang, X., Treiber, F. A., Davis, H., Leverett, S., Su, S. & Kapuku, G., Dec 2016, In : Journal of the American Heart Association. 5, 12, e004147.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Young Adult
Growth
Body Mass Index
Cerebrovascular Disorders
14 Citations (Scopus)

Heritabilities of lipids in young European American and African American twins

Iliadou, A., Snieder, H., Wang, X., Treiber, F. A. & Davis, C. L., Oct 1 2005, In : Twin Research and Human Genetics. 8, 5, p. 492-498 7 p.

Research output: Contribution to journalArticle

African Americans
Lipids
Twin Studies
HDL Lipoproteins
LDL Lipoproteins
28 Citations (Scopus)

Heritability of Arterial Stiffness in Black and White American Youth and Young Adults

Ge, D., Young, T. W., Wang, X., Kapuku, K. G., Treiber, F. A. & Snieder, H., Oct 1 2007, In : American Journal of Hypertension. 20, 10, p. 1065-1072 8 p.

Research output: Contribution to journalArticle

Vascular Stiffness
Pulse Wave Analysis
Young Adult
Blood Pressure
Foot
20 Citations (Scopus)

Heritability of insulin sensitivity and lipid profile depend on BMI: Evidence for gene-obesity interaction

Wang, X., Ding, X., Su, S., Spector, T. D., Mangino, M., Iliadou, A. & Snieder, H., Dec 1 2009, In : Diabetologia. 52, 12, p. 2578-2584 7 p.

Research output: Contribution to journalArticle

Insulin Resistance
Obesity
Lipids
Triglycerides
Genes
432 Citations (Scopus)

Identification of seven loci affecting mean telomere length and their association with disease

Codd, V., Nelson, C. P., Albrecht, E., Mangino, M., Deelen, J., Buxton, J. L., Hottenga, J. J., Fischer, K., Esko, T., Surakka, I., Broer, L., Nyholt, D. R., Leach, I. M., Salo, P., Hägg, S., Matthews, M. K., Palmen, J., Norata, G. D., O'Reilly, P. F., Saleheen, D. & 79 others, Amin, N., Balmforth, A. J., Beekman, M., De Boer, R. A., Böhringer, S., Braund, P. S., Burton, P. R., Craen, A. J. M., Denniff, M., Dong, Y., Douroudis, K., Dubinina, E., Eriksson, J. G., Garlaschelli, K., Guo, D., Hartikainen, A. L., Henders, A. K., Houwing-Duistermaat, J. J., Kananen, L., Karssen, L. C., Kettunen, J., Klopp, N., Lagou, V., Van Leeuwen, E. M., Madden, P. A., Mägi, R., Magnusson, P. K. E., Männistö, S., McCarthy, M. I., Medland, S. E., Mihailov, E., Montgomery, G. W., Oostra, B. A., Palotie, A., Peters, A., Pollard, H., Pouta, A., Prokopenko, I., Ripatti, S., Salomaa, V., Suchiman, H. E. D., Valdes, A. M., Verweij, N., Viñuela, A., Wang, X., Wichmann, H. E., Widen, E., Willemsen, G., Wright, M. J., Xia, K., Xiao, X., Van Veldhuisen, D. J., Catapano, A. L., Tobin, M. D., Hall, A. S., Blakemore, A. I. F., Van Gilst, W. H., Zhu, H., Erdmann, J., Reilly, M. P., Kathiresan, S., Schunkert, H., Talmud, P. J., Pedersen, N. L., Perola, M., Ouwehand, W., Kaprio, J., Martin, N. G., Van Duijn, C. M., Hovatta, I., Gieger, C., Metspalu, A., Boomsma, D. I., Jarvelin, M. R., Slagboom, P. E., Thompson, J. R., Spector, T. D., Van Der Harst, P. & Samani, N. J., Apr 1 2013, In : Nature Genetics. 45, 4, p. 422-427 6 p.

Research output: Contribution to journalArticle

Telomere
Leukocytes
Coronary Artery Disease
Idiopathic Pulmonary Fibrosis
Single Nucleotide Polymorphism
5 Citations (Scopus)

Identifying genetic variants for heart rate variability in the acetylcholine pathway

Riese, H., Muñoz, L. M., Hartman, C. A., Ding, X., Su, S., Oldehinkel, A. J., Van Roon, A. M., Van Der Most, P. J., Lefrt, J., Gansevoort, R. T., Van Der Harst, P., Verweij, N., Licht, C. M. M., Boomsma, D. I., Hottenga, J. J., Willemsen, G., Penninx, B. W. J. H., Nolte, I. M., De Geus, E. J. C., Wang, X. & 1 others, Snieder, H., Nov 10 2014, In : PloS one. 9, 11, e112476.

Research output: Contribution to journalArticle

acetylcholine
Acetylcholine
heart rate
Heart Rate
Genes
24 Citations (Scopus)

Influence of the eNOS gene on development of blood pressure and left ventricular mass: Longitudinal findings in multiethnic youth

Zhu, H., Wang, X., Dong, Y., Treiber, F. A. & Snieder, H., Jan 1 2005, In : Pharmacogenetics and Genomics. 15, 9, p. 669-675 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Haplotypes
Blood Pressure
Introns
Genes
19 Citations (Scopus)

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis

Xu, Y., Wang, Y., Yan, S., Zhou, Y., Yang, Q., Pan, Y., Zeng, X., An, X., Liu, Z., Wang, L., Xu, J., Cao, Y., Fulton, D. J., Weintraub, N. L., Bagi, Z., Hoda, MD. N., Wang, X., Li, Q., Hong, M., Jiang, X. & 4 others, Boison, D., Weber, C., Wu, C. & Huo, Y., Sep 2017, In : EMBO Molecular Medicine. 9, 9, p. 1263-1278 16 p.

Research output: Contribution to journalArticle

Adenosine Kinase
Epigenomics
Adenosine
Endothelial Cells
Methylation
2 Citations (Scopus)

Leisure-time physical activity and DNA methylation age - A twin study

Sillanpää, E., Ollikainen, M., Kaprio, J., Wang, X., Leskinen, T., Kujala, U. M. & Törmäkangas, T., Jan 19 2019, In : Clinical epigenetics. 11, 1, 12.

Research output: Contribution to journalArticle

Twin Studies
Leisure Activities
DNA Methylation
Exercise
Epigenomics
90 Citations (Scopus)

Leukocyte telomere length in healthy caucasian and african-american adolescents: Relationships with race, sex, adiposity, adipokines, and physical activity

Zhu, H., Wang, X., Gutin, B., Davis, C. L., Keeton, D., Thomas, J., Stallmann-Jorgensen, I., Mooken, G., Bundy, V., Snieder, H., Van Der Harst, P. & Dong, Y., Feb 1 2011, In : Journal of Pediatrics. 158, 2, p. 215-220 6 p.

Research output: Contribution to journalArticle

Adipokines
Telomere
Adiposity
African Americans
Leukocytes
8 Citations (Scopus)

Linkage analysis of 2q14-q23 and 5q32 with blood pressure quantitative traits in Chinese sib pairs

Ge, D., Yang, W., Huang, J., Yao, C., Xu, X., Gan, W., Zhao, J., Liu, D., Wang, X., Duan, X., Hui, R., Shen, Y., Yao, Z., Qiang, B. & Gu, D., Feb 1 2003, In : Journal of hypertension. 21, 2, p. 305-310 6 p.

Research output: Contribution to journalArticle

Blood Pressure
Microsatellite Repeats
Adrenergic Receptors
Alleles
Hypertension
21 Citations (Scopus)

Obesity is associated with more activated neutrophils in African American male youth

Xu, X., Su, S., Wang, X., Barnes, V. A., De Miguel, C., Ownby, D. R., Pollock, J., Snieder, H. & Chen, W., Jan 10 2015, In : International Journal of Obesity. 39, 1, p. 26-32 7 p.

Research output: Contribution to journalArticle

African Americans
Neutrophils
Obesity
Neutrophil Activation
Leukocytes
139 Citations (Scopus)

Obesity related methylation changes in DNA of peripheral blood leukocytes

Wang, X., Zhu, H., Snieder, H., Su, S., Munn, D. H., Harshfield, G. A., Maria, B. L., Dong, Y., Treiber, F., Gutin, B. & Shi, H., Dec 21 2010, In : BMC Medicine. 8, 87.

Research output: Contribution to journalArticle

Methylation
Leukocytes
Obesity
DNA
Genes
78 Citations (Scopus)

Obesity reveals an association between blood pressure and the G-protein β3-subunit gene: A study of female dizygotic twins

Dong, Y., Zhu, H., Wang, X., Dalageorgou, C., Carter, N., Spector, T. D. & Snieder, H., Jul 1 2004, In : Pharmacogenetics. 14, 7, p. 419-427 9 p.

Research output: Contribution to journalArticle

Dizygotic Twins
Protein Subunits
GTP-Binding Proteins
Obesity
Blood Pressure
18 Citations (Scopus)

Paraoxonase gene cluster variations associated with coronary heart disease in Chinese Han women

Su, S., Chen, J. H., Huang, J. F., Wang, X., Zhao, J. G., Shen, Y., Qiang, B. Q. & Gu, D. F., Jul 20 2005, In : Chinese Medical Journal. 118, 14, p. 1167-1174 8 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Multigene Family
Haplotypes
Coronary Disease
LDL Lipoproteins
15 Citations (Scopus)

Phenotypic alteration of CD8+ T cells in chronic lymphocytic leukemia is associated with epigenetic reprogramming

Wu, J., Xu, X., Lee, E. J., Shull, A. Y., Pei, L., Awan, F., Wang, X., Choi, J-H., Deng, L., Xin, H. B., Zhong, W., Liang, J., Miao, Y., Wu, Y., Fan, L., Li, J., Xu, W. & Shi, H., Jan 1 2016, In : Oncotarget. 7, 26, p. 40558-40570 13 p.

Research output: Contribution to journalArticle

T-Cell Prolymphocytic Leukemia
Epigenomics
B-Cell Chronic Lymphocytic Leukemia
T-Lymphocytes
DNA Methylation
15 Citations (Scopus)

Phosphatidylinositol 3-kinase p85α regulatory subunit gene PIK3R1 haplotype is associated with body fat and serum leptin in a female twin population

Jamshidi, Y., Snieder, H., Wang, X., Pavitt, M. J., Spector, T. D., Carter, N. D. & O'Dell, S. D., Nov 1 2006, In : Diabetologia. 49, 11, p. 2659-2667 9 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Regulator Genes
Leptin
Haplotypes
Adipose Tissue
22 Citations (Scopus)

Plasminogen activator inhibitor-1 gene selection of tagging single nucleotide polymorphisms and association with coronary heart disease

Su, S., Chen, S., Zhao, J., Huang, J., Wang, X., Chen, R. & Gu, D., Apr 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 4, p. 948-954 7 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Single Nucleotide Polymorphism
Coronary Disease
Haplotypes
Alleles

Polymorphisms screening of PON gene cluster

Wang, X., Fan, Z. J., Huang, J. F., Su, S., Zhao, J. G. & Gu, D. F., Jan 1 2005, In : Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji. 27, 4, p. 539-543 5 p.

Research output: Contribution to journalArticle

Multigene Family
Population
Genetic Promoter Regions
Genes
Transcription Initiation Site
19 Citations (Scopus)

Proopiomelanocortin gene variants are associated with serum leptin and body fat in a normal female population

Chen, Y., Snieder, H., Wang, X., Kaviya, B., McCaffrey, C., Spector, T. D., Carter, N. D. & O'Dell, S. D., Jun 1 2005, In : European Journal of Human Genetics. 13, 6, p. 772-780 9 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Leptin
Adipose Tissue
Single Nucleotide Polymorphism
Fats
16 Citations (Scopus)

Prostasin: A possible candidate gene for human hypertension

Zhu, H., Guo, D., Li, K., Yan, W., Tan, Y., Wang, X., Treiber, F. A., Chao, J., Snieder, H. & Dong, Y., Sep 1 2008, In : American journal of hypertension. 21, 9, p. 1028-1033 6 p.

Research output: Contribution to journalArticle

Genotype
Hypertension
Single Nucleotide Polymorphism
Genes
Blood Pressure
35 Citations (Scopus)

Protein tyrosine phosphatase-1B gene PTPN1: Selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population

Spencer-Jones, N. J., Wang, X., Snieder, H., Spector, T. D., Carter, N. D. & O'Dell, S. D., Nov 1 2005, In : Diabetes. 54, 11, p. 3296-3304 9 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Single Nucleotide Polymorphism
Insulin Resistance
Adipose Tissue
Haplotypes
7 Citations (Scopus)

Pulse wave velocity in elastic and muscular arteries: Tracking stability and association with anthropometric and hemodynamic measurements

Ye, C., Pan, Y., Xu, X., Su, S., Snieder, H., Treiber, F., Kapuku, G. & Wang, X., Nov 1 2016, In : Hypertension Research. 39, 11, p. 786-791 6 p.

Research output: Contribution to journalArticle

Pulse Wave Analysis
Arteries
Hemodynamics
Blood Pressure
Obesity
8 Citations (Scopus)

Racial/ethnic differences in the association of childhood adversities with depression and the role of resilience

Youssef, N. A., Belew, D., Hao, G., Wang, X., Treiber, F. A., Stefanek, M. E., Yassa, M., Boswell, E., McCall, W. V. & Su, S., Jan 15 2017, In : Journal of Affective Disorders. 208, p. 577-581 5 p.

Research output: Contribution to journalArticle

Depression
Wounds and Injuries
Young Adult
Therapeutic Human Experimentation
African Americans

Reply to manuscript IJC-D-12-04197 entitled "Does alpha-lipoic acid treatment play a role on oxidative stress and insulin resistance in overweight/obese patients?" by MD Turgay Ulas

Yan, W., Li, N., Hu, X., Huang, Y., Zhang, W., Wang, Q., Wang, F., Wang, C., Zhai, X., Xu, R., Yan, K., Ding, X. & Wang, X., Sep 30 2013, In : International Journal of Cardiology. 168, 2, 1 p.

Research output: Contribution to journalArticle

Thioctic Acid
alpha-Linolenic Acid
Manuscripts
Insulin Resistance
Oxidative Stress
15 Citations (Scopus)

SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women

Jamshidi, Y., Gooljar, S. B., Snieder, H., Wang, X., Ge, D., Swaminathan, R., Spector, T. D. & O'Dell, S. D., Oct 1 2007, In : Atherosclerosis. 194, 2, p. e26-e33

Research output: Contribution to journalArticle

Apolipoproteins B
Phosphatidylinositol 3-Kinases
LDL Cholesterol
Single Nucleotide Polymorphism
Serum
4 Citations (Scopus)

Specific genetic influences on nighttime blood pressure

Xu, X., Su, S., Treiber, F. A., Vlietinck, R., Fagard, R., Derom, C., Gielen, M., Loos, R. J. F., Snieder, H. & Wang, X., Apr 1 2015, In : American journal of hypertension. 28, 4, p. 440-443 4 p.

Research output: Contribution to journalArticle

Blood Pressure
Twin Studies
Meta-Analysis
Embryonic and Fetal Development
Genes
12 Citations (Scopus)

Stress-induced sodium excretion a new intermediate phenotype to study the early genetic etiology of hypertension?

Ge, D., Su, S., Zhu, H., Dong, Y., Wang, X., Harshfield, G. A., Treiber, F. A. & Snieder, H., Feb 1 2009, In : Hypertension. 53, 2, p. 262-269 8 p.

Research output: Contribution to journalArticle

Sodium
Hypertension
Phenotype
Dizygotic Twins
Natriuresis
20 Citations (Scopus)

The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins

Zhu, H., Lu, Y., Wang, X., Treiber, F. A., Harshfield, G. A., Snieder, H. & Dong, Y., Jan 1 2006, In : American journal of hypertension. 19, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinase 4
Haplotypes
Blood Pressure
Genes
Homozygote
24 Citations (Scopus)

The G protein-coupled receptor kinase 4 gene modulates stress-induced sodium excretion in black normotensive adolescents

Zhu, H., Lu, Y., Wang, X., Snieder, H., Treiber, F. A., Harshfield, G. A. & Dong, Y., Oct 1 2006, In : Pediatric research. 60, 4, p. 440-442 3 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinase 4
Sodium
Genes
Blood Pressure
Video Games
14 Citations (Scopus)

Thrombospondin-4 A387P polymorphism is not associated with coronary artery disease and myocardial infarction in the Chinese Han population

Zhou, X., Huang, J., Chen, J., Zhao, J., Yang, W., Wang, X. & Gu, D., May 1 2004, In : Clinical Science. 106, 5, p. 495-500 6 p.

Research output: Contribution to journalArticle

Myocardial Infarction
Coronary Artery Disease
Population
Restriction Fragment Length Polymorphisms
Polymerase Chain Reaction
8 Citations (Scopus)

TUB is a candidate gene for late-onset obesity in women

Snieder, H., Wang, X., Shiri-Sverdlov, R., Van Vliet-Ostaptchouk, J. V., Hofker, M. H., Perks, U., Spector, T. D. & O'Dell, S. D., Jan 1 2008, In : Diabetologia. 51, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Abdominal Obesity
Single Nucleotide Polymorphism
Obesity
Genes
Waist Circumference
1 Citation (Scopus)

Urinary prostasin excretion is associated with adiposity in nonhypertensive African-American adolescents

Guo, D. H., Parikh, S. J., Chao, J., Pollock, N. K., Wang, X., Snieder, H., Navis, G., Wilson, J. G., Bhagatwala, J., Zhu, H. & Dong, Y., Aug 1 2013, In : Pediatric research. 74, 2, p. 206-210 5 p.

Research output: Contribution to journalArticle

Adiposity
African Americans
Blood Pressure
Aldosterone
Adipose Tissue

Urinary prostasin excretion is associated with adiposity in non-hypertensive African American adolescents

Guo, D-H., Parikh, S., Chao, J., Pollock, N. K., Wang, X., Snieder, H., Navis, G., Bhagatwala, J., Zhu, H. & Dong, Y., 2013, In : Pediatric Research. In Press

Research output: Contribution to journalArticle

25 Citations (Scopus)

Waist circumference cutoff points in school-aged Chinese Han and Uygur children

Yan, W., Yao, H., Dai, J., Cui, J., Chen, Y., Yang, X., Harshfield, G. A. & Wang, X., Jul 1 2008, In : Obesity. 16, 7, p. 1687-1692 6 p.

Research output: Contribution to journalArticle

Waist Circumference
Weights and Measures
Age Distribution
Adiposity
Fasting
Chapter
1 Citation (Scopus)

Familial aggregation of blood pressure

Wang, X. & Snieder, H., Jan 1 2013, Pediatric Hypertension: Third Edition. Humana Press Inc., p. 195-209 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Twin Studies
Blood Pressure
Hypotension
Cross-Sectional Studies
Hypertension

Heritability and familial aggregation of blood pressure

Wang, X. & Snieder, H., Jan 1 2018, Pediatric Hypertension. Springer International Publishing, p. 159-176 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Blood Pressure
Twin Studies
Hypotension
Epidemiologic Studies
Cross-Sectional Studies
4 Citations (Scopus)

Role of Gene-Stress Interactions in Gene-Finding Studies

Snieder, H., Wang, X., Lagou, V., Penninx, B. W. J. H., Riese, H. & Hartman, C. A., Aug 12 2008, Genetic Effects on Environmental Vulnerability to Disease. wiley, p. 71-82 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genes
Genome-Wide Association Study
Single Nucleotide Polymorphism
Endophenotypes
Gene-Environment Interaction
Comment/debate
Lipids
Genes
hydroquinone
21 Citations (Scopus)

Genome-wide association studies and beyond: What's next in blood pressure genetics?

Wang, X. & Snieder, H., Dec 1 2010, In : Hypertension. 56, 6, p. 1035-1037 3 p.

Research output: Contribution to journalComment/debate

Ambulatory Blood Pressure Monitoring
Genetic Loci
Genome-Wide Association Study
Genetic Association Studies
Genetic Predisposition to Disease
Conference contribution
3 Citations (Scopus)

5. Role of gene-stress interactions in gene-finding studies

Snieder, H., Wang, X., Lagou, V., Penninx, B. W. J. H., Riese, H. & Hartman, C. A., Nov 19 2008, Genetic Effects on Environmental Vulnerability to Disease. p. 71-82 12 p. (Novartis Foundation Symposium; vol. 293).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Genes
Genome-Wide Association Study
Single Nucleotide Polymorphism
Endophenotypes
Gene-Environment Interaction
Editorial

Assessing genetic risk of hypertension at an early age: future research directions

Wang, X. & Snieder, H., Nov 2 2017, In : Expert Review of Cardiovascular Therapy. 15, 11, p. 809-812 4 p.

Research output: Contribution to journalEditorial

Blood Pressure
Hypertension
Direction compound
Letter
5 Citations (Scopus)

Ethnic differences in heart rate variability: Does ultralow-frequency heart rate variability really measure autonomic tone?

Thayer, J. F., Wang, X. & Snieder, H., Sep 1 2006, In : American Heart Journal. 152, 3

Research output: Contribution to journalLetter

Autonomic Nervous System
Ethnic Groups
African Americans
Research Design
Heart Rate
11 Citations (Scopus)

Waist-to-height ratio and BMI predict different cardiovascular risk factors in Chinese children [6]

Yan, W., Wang, X., Yao, H., Dai, J., Zheng, Y., Yang, X., Yibulayin, X. & Cui, J., Dec 1 2006, In : Diabetes Care. 29, 12, p. 2760-2761 2 p.

Research output: Contribution to journalLetter

Body Size
China
Body Mass Index
Cardiovascular Diseases
Waist-Height Ratio
Review article
22 Citations (Scopus)

Effects of angiotensinogen and angiotensin II type I receptor genes on blood pressure and left ventricular mass trajectories in multiethnic youth

Wang, X., Zhu, H., Dong, Y., Treiber, F. A. & Snieder, H., Jun 1 2006, In : Twin Research and Human Genetics. 9, 3, p. 393-402 10 p.

Research output: Contribution to journalReview article

Angiotensin I
Angiotensinogen
Angiotensin Receptors
Haplotypes
Blood Pressure
55 Citations (Scopus)

Ethnic differences in resting heart rate variability: A systematic review and meta-analysis

Hill, L. K., Hu, D. D., Koenig, J., Sollers, J. J., Kapuku, K. G., Wang, X., Snieder, H. & Thayer, J. F., Jan 1 2015, In : Psychosomatic Medicine. 77, 1, p. 16-25 10 p.

Research output: Contribution to journalReview article

Meta-Analysis
Heart Rate
African Americans
Cardiovascular Diseases
Research
22 Citations (Scopus)

The Georgia Cardiovascular Twin Study: Influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes

Ge, D., Dong, Y., Wang, X., Treiber, F. A. & Snieder, H., Dec 1 2006, In : Twin Research and Human Genetics. 9, 6, p. 965-970 6 p.

Research output: Contribution to journalReview article

Twin Studies
Genetic Predisposition to Disease
Type 2 Diabetes Mellitus
Cardiovascular Diseases
Longitudinal Studies
8 Citations (Scopus)

Update on G-protein polymorphisms in hypertension

Zhu, H., Wang, X., Lu, Y., Poola, J., Momin, Z., Harshfield, G. A., Snieder, H. & Dong, Y., Apr 1 2006, In : Current Hypertension Reports. 8, 1, p. 23-29 7 p.

Research output: Contribution to journalReview article

GTP-Binding Proteins
Hypertension
Genes
Pertussis Toxin
Protein Subunits