• 4514 Citations
  • 29 h-Index
20022020

Research output per year

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Research Output

Review article

Effects of angiotensinogen and angiotensin II type I receptor genes on blood pressure and left ventricular mass trajectories in multiethnic youth

Wang, X., Zhu, H., Dong, Y., Treiber, F. A. & Snieder, H., Jun 1 2006, In : Twin Research and Human Genetics. 9, 3, p. 393-402 10 p.

Research output: Contribution to journalReview article

22 Scopus citations

Ethnic differences in resting heart rate variability: A systematic review and meta-analysis

Hill, L. K., Hu, D. D., Koenig, J., Sollers, J. J., Kapuku, G., Wang, X., Snieder, H. & Thayer, J. F., Jan 1 2015, In : Psychosomatic Medicine. 77, 1, p. 16-25 10 p.

Research output: Contribution to journalReview article

68 Scopus citations

The Georgia Cardiovascular Twin Study: Influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes

Ge, D., Dong, Y., Wang, X., Treiber, F. A. & Snieder, H., Dec 1 2006, In : Twin Research and Human Genetics. 9, 6, p. 965-970 6 p.

Research output: Contribution to journalReview article

22 Scopus citations

Update on G-protein polymorphisms in hypertension

Zhu, H., Wang, X., Lu, Y., Poola, J., Momin, Z., Harshfield, G. A., Snieder, H. & Dong, Y., Apr 1 2006, In : Current Hypertension Reports. 8, 1, p. 23-29 7 p.

Research output: Contribution to journalReview article

8 Scopus citations
Letter

Ethnic differences in heart rate variability: Does ultralow-frequency heart rate variability really measure autonomic tone?

Thayer, J. F., Wang, X. & Snieder, H., Sep 1 2006, In : American Heart Journal. 152, 3

Research output: Contribution to journalLetter

5 Scopus citations

Waist-to-height ratio and BMI predict different cardiovascular risk factors in Chinese children [6]

Yan, W., Wang, X., Yao, H., Dai, J., Zheng, Y., Yang, X., Yibulayin, X. & Cui, J., Dec 1 2006, In : Diabetes Care. 29, 12, p. 2760-2761 2 p.

Research output: Contribution to journalLetter

13 Scopus citations
Editorial

Assessing genetic risk of hypertension at an early age: future research directions

Wang, X. & Snieder, H., Nov 2 2017, In : Expert Review of Cardiovascular Therapy. 15, 11, p. 809-812 4 p.

Research output: Contribution to journalEditorial

Conference contribution

5. Role of gene-stress interactions in gene-finding studies

Snieder, H., Wang, X., Lagou, V., Penninx, B. W. J. H., Riese, H. & Hartman, C. A., Nov 19 2008, Genetic Effects on Environmental Vulnerability to Disease. p. 71-82 12 p. (Novartis Foundation Symposium; vol. 293).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Genome-wide association studies and beyond: What's next in blood pressure genetics?

Wang, X. & Snieder, H., Dec 1 2010, In : Hypertension. 56, 6, p. 1035-1037 3 p.

Research output: Contribution to journalComment/debate

21 Scopus citations
Chapter

Familial aggregation of blood pressure

Wang, X. & Snieder, H., Jan 1 2013, Pediatric Hypertension: Third Edition. Humana Press Inc., p. 195-209 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Heritability and familial aggregation of blood pressure

Wang, X. & Snieder, H., Jan 1 2018, Pediatric Hypertension. Springer International Publishing, p. 159-176 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Role of Gene-Stress Interactions in Gene-Finding Studies

Snieder, H., Wang, X., Lagou, V., Penninx, B. W. J. H., Riese, H. & Hartman, C. A., Aug 12 2008, Genetic Effects on Environmental Vulnerability to Disease. wiley, p. 71-82 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
Article

[The effect of oral alpha-lipoic acid in overweight/obese individuals on brachial-ankle pulse wave velocity and supine blood pressure: a randomized, crossover, double-blind, placebo-controlled trial].

Huang, Y. D., Li, N., Zhang, W. G., Hu, X. J., Wang, Q., Wang, C. C., Xu, R. W., Yan, K., Hou, X. Y., Naerkeze, Wang, X. & Yan, W. L., Mar 2011, In : Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi. 32, 3, p. 290-296 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood

Li, Z., Snieder, H., Harshfield, G. A., Treiber, F. A. & Wang, X., Aug 12 2009, In : Hypertension Research. 32, 5, p. 404-410 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

A 2-step penalized regression method for family-based next-generation sequencing association studies

Ding, X., Su, S., Nandakumar, K., Wang, X. & Fardo, D. W., Jun 17 2014, In : BMC Proceedings. 8, S25.

Research output: Contribution to journalArticle

4 Scopus citations

Accuracy of self-reported anthropometric measures — Findings from the Finnish Twin Study

Tuomela, J., Kaprio, J., Sipilä, P. N., Silventoinen, K., Wang, X., Ollikainen, M. & Piirtola, M., Nov 1 2019, In : Obesity Research and Clinical Practice. 13, 6, p. 522-528 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity

Kyriakou, T., Collins, L. J., Spencer-Jones, N. J., Malcolm, C., Wang, X., Snieder, H., Swaminathan, R., Burling, K. A., Hart, D. J., Spector, T. D. & O'Dell, S. D., Aug 1 2008, In : Journal of Human Genetics. 53, 8, p. 718-727 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Adverse childhood experiences and blood pressure trajectories from childhood to young adulthood: the Georgia stress and Heart study

Su, S., Wang, X., Pollock, J. S., Treiber, F. A., Xu, X., Snieder, H., McCall, W. V., Stefanek, M. & Harshfield, G. A., May 12 2015, In : Circulation. 131, 19, p. 1674-81 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

Adverse childhood experiences are associated with detrimental hemodynamics and elevated circulating endothelin-1 in adolescents and young adults

Su, S., Wang, X., Kapuku, G. K., Treiber, F. A., Pollock, D. M., Harshfield, G. A., McCall, W. V. & Pollock, J. S., Jul 2014, In : Hypertension. 64, 1, p. 201-207 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

A genome-wide methylation study of severe vitamin d deficiency in African American adolescents

Zhu, H., Wang, X., Shi, H., Su, S., Harshfield, G. A., Gutin, B., Snieder, H. & Dong, Y., Jan 1 2013, In : Journal of Pediatrics. 162, 5

Research output: Contribution to journalArticle

51 Scopus citations

A Genome-Wide Methylation Study on Essential Hypertension in Young African American Males

Wang, X., Falkner, B., Zhu, H., Shi, H., Su, S., Xu, X., Sharma, A. K., Dong, Y., Treiber, F., Gutin, B., Harshfield, G. & Snieder, H., Jan 17 2013, In : PloS one. 8, 1, e53938.

Research output: Contribution to journalArticle

44 Scopus citations

A genome-wide methylation study on obesity: Differential variability and differential methylation

Xu, X., Su, S., Barnes, V. A., De Miguel, C., Pollock, J., Ownby, D., Shi, H., Zhu, H., Snieder, H. & Wang, X., May 2013, In : Epigenetics. 8, 5, p. 522-533 12 p.

Research output: Contribution to journalArticle

100 Scopus citations

A longitudinal study in youth of heart rate variability at rest and in response to stress

Li, Z., Snieder, H., Su, S., Ding, X., Thayer, J. F., Treiber, F. A. & Wang, X., Sep 1 2009, In : International Journal of Psychophysiology. 73, 3, p. 212-217 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

A longitudinal study of blood pressure variability in African-American and European American youth

Li, Z., Snieder, H., Su, S., Harshfield, G. A., Treiber, F. A. & Wang, X., Apr 1 2010, In : Journal of hypertension. 28, 4, p. 715-722 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension

EchoGen consortium, CHARGE-HF consortium, International Consortium for Blood Pressure GWAS (ICBP), CARDIoGRAM consortium, CKDGen Consortium & KidneyGen Consortium, Mar 18 2015, In : PLoS Genetics. 11, 3, e1005035.

Research output: Contribution to journalArticle

61 Scopus citations

A Method to Detect Differentially Methylated Loci With Next-Generation Sequencing

Xu, H., Podolsky, R. H., Ryu, D., Wang, X., Su, S., Shi, H. & George, V., May 1 2013, In : Genetic Epidemiology. 37, 4, p. 377-382 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression

Wang, X., Pan, Y., Zhu, H., Hao, G., Huang, Y., Barnes, V., Shi, H., Snieder, H., Pankow, J., North, K., Grove, M., Guan, W., Demerath, E., Dong, Y. & Su, S., Jan 1 2018, In : Clinical epigenetics. 10, 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

Angiotensin II type I receptor gene and myocardial infarction: Tagging SNPs and haplotype based association study. The Beijing atherosclerosis study

Su, S., Chen, J., Zhao, J., Huang, J., Wang, X., Chen, R. & Gu, D., Oct 1 2004, In : Pharmacogenetics. 14, 10, p. 673-681 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese

Wang, X. L., Fan, Z. J., Huang, J. F., Su, S. Y., Zhao, J. G. & Gu, D. F., Jul 1 2005, In : Acta Genetica Sinica. 32, 7, p. 675-681 7 p.

Research output: Contribution to journalArticle

Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals

Zhou, H., Lei, X., Benson, T., Mintz, J., Xu, X., Harris, R. B., Weintraub, N. L., Wang, X. & Chen, W., Oct 1 2015, In : Journal of Lipid Research. 56, 10, p. 1912-1925 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Beyond genome-wide association studies: New strategies for identifying genetic determinants of hypertension

Wang, X., Prins, B. P., Sõber, S., Laan, M. & Snieder, H., Dec 1 2011, In : Current Hypertension Reports. 13, 6, p. 442-451 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Blood pressure trajectories from childhood to young adulthood associated with cardiovascular risk

Hao, G., Wang, X., Treiber, F. A., Harshfield, G., Kapuku, G. & Su, S., Mar 1 2017, In : Hypertension. 69, 3, p. 435-442 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Body mass index drives changes in DNA methylation: A longitudinal study

Sun, D., Zhang, T., Su, S., Hao, G., Chen, T., Li, Q. Z., Bazzano, L., He, J., Wang, X., Li, S. & Chen, W., Oct 11 2019, In : Circulation research. 125, 9, p. 824-833 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
10 Scopus citations

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In : Journal of the American Heart Association. 6, 6, e004918.

Research output: Contribution to journalArticle

36 Scopus citations

Common polymorphisms in SOCS3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins

Jamshidi, Y., Snieder, H., Wang, X., Spector, T. D., Carter, N. D. & O'Dell, S. D., Feb 1 2006, In : Diabetologia. 49, 2, p. 306-310 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Common STAT3 variants are not associated with obesity or insulin resistance in female twins

Jamshidi, Y., Kyriakou, T., Gooljar, S. B., Collins, L. J., Lane, C. A., Snieder, H., Wang, X., Spector, T. D. & O'Dell, S. D., Jul 1 2007, In : Obesity. 15, 7, p. 1634-1639 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Determinants of pulse wave velocity trajectories from youth to young adulthood: The Georgia Stress and Heart Study

Liang, X., Su, S., Hao, G., Snieder, H., Treiber, F., Kapuku, G. & Wang, X., Mar 2019, In : Journal of hypertension. 37, 3, p. 563-571 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Dietary sodium, adiposity, and inflammation in healthy adolescents

Zhu, H., Pollock, N. K., Kotak, I., Gutin, B., Wang, X., Bhagatwala, J., Parikh, S., Harshfield, G. A. & Dong, Y., Jan 1 2014, In : Pediatrics. 133, 3, p. e635-e642

Research output: Contribution to journalArticle

62 Scopus citations

Differential methylation tests of regulatory regions

Ryu, D., Xu, H., George, V., Su, S., Wang, X., Shi, H. & Podolsky, R. H., Jun 1 2016, In : Statistical Applications in Genetics and Molecular Biology. 15, 3, p. 237-251 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Discovery and Validation of a Novel Neutrophil Activation Marker Associated with Obesity

Pan, Y., Choi, J-H., Shi, H., Zhang, L., Su, S. & Wang, X., Dec 1 2019, In : Scientific reports. 9, 1, 3433.

Research output: Contribution to journalArticle

1 Scopus citations

DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring

Küpers, L. K., Xu, X., Jankipersadsing, S. A., Vaez, A., La Bastide-van Gemert, S., Scholtens, S., Nolte, I. M., Richmond, R. C., Relton, C. L., Felix, J. F., Duijts, L., Van Meurs, J. B., Tiemeier, H., Jaddoe, V. W., Wang, X., Corpeleijn, E. & Snieder, H., Aug 2015, In : International Journal of Epidemiology. 44, 4, p. 1224-1237 14 p.

Research output: Contribution to journalArticle

90 Scopus citations

DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation

Su, S., Zhu, H., Xu, X., Wang, X., Wang, X., Dong, Y., Kapuku, K. G., Treiber, F., Gutin, B., Harshfield, G. A. & Snieder, H., Jun 2014, In : Twin Research and Human Genetics. 17, 3, p. 183-191 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: A double-blinded, randomized, controlled, cross-over intervention trial

Yan, W., Li, N., Hu, X., Huang, Y., Zhang, W., Wang, Q., Wang, F., Wang, C., Zhai, X., Xu, R., Yan, K., Ding, X. & Wang, X., Jul 31 2013, In : International Journal of Cardiology. 167, 2, p. 602-603 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effect of the baseline pulse wave velocity on short term and long term blood pressure control in primary hypertension

Fan, Y., Gao, W., Li, J., Fan, F., Qin, X., Liu, L., Cheng, X., Xu, X., Wang, X., Wang, B. & Huo, Y., Jan 1 2020, (Accepted/In press) In : International Journal of Cardiology.

Research output: Contribution to journalArticle

Effects of Dopamine Receptor Type 1 and Gs Protein α Subunit Gene Polymorphisms on Blood Pressure at Rest and in Response to Stress

Lu, Y., Zhu, H., Wang, X., Snieder, H., Huang, Y., Harshfield, G. A., Treiber, F. A. & Dong, Y., Aug 1 2006, In : American Journal of Hypertension. 19, 8, p. 832-836 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effects of Maternal Vitamin D3 Supplementation on Offspring Epigenetic Clock of Gestational Age at Birth: A Post-hoc Analysis of a Randomized Controlled Trial

Chen, L., Wagner, C. L., Dong, Y., Wang, X., Shary, J. R., Huang, Y., Hollis, B. W. & Zhu, H., Jan 1 2020, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle