• 4155 Citations
  • 27 h-Index
20022019
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Research Output 2002 2019

2011
90 Citations (Scopus)

Leukocyte telomere length in healthy caucasian and african-american adolescents: Relationships with race, sex, adiposity, adipokines, and physical activity

Zhu, H., Wang, X., Gutin, B., Davis, C. L., Keeton, D., Thomas, J., Stallmann-Jorgensen, I., Mooken, G., Bundy, V., Snieder, H., Van Der Harst, P. & Dong, Y., Feb 1 2011, In : Journal of Pediatrics. 158, 2, p. 215-220 6 p.

Research output: Contribution to journalArticle

Adipokines
Telomere
Adiposity
African Americans
Leukocytes
2010
38 Citations (Scopus)

A longitudinal study of blood pressure variability in African-American and European American youth

Li, Z., Snieder, H., Su, S., Harshfield, G. A., Treiber, F. A. & Wang, X., Apr 1 2010, In : Journal of hypertension. 28, 4, p. 715-722 8 p.

Research output: Contribution to journalArticle

African Americans
Longitudinal Studies
Blood Pressure
Hypertension
Adiposity
21 Citations (Scopus)

Genome-wide association studies and beyond: What's next in blood pressure genetics?

Wang, X. & Snieder, H., Dec 1 2010, In : Hypertension. 56, 6, p. 1035-1037 3 p.

Research output: Contribution to journalComment/debate

Ambulatory Blood Pressure Monitoring
Genetic Loci
Genome-Wide Association Study
Genetic Association Studies
Genetic Predisposition to Disease
139 Citations (Scopus)

Obesity related methylation changes in DNA of peripheral blood leukocytes

Wang, X., Zhu, H., Snieder, H., Su, S., Munn, D. H., Harshfield, G. A., Maria, B. L., Dong, Y., Treiber, F., Gutin, B. & Shi, H., Dec 21 2010, In : BMC Medicine. 8, 87.

Research output: Contribution to journalArticle

Methylation
Leukocytes
Obesity
DNA
Genes
2009
41 Citations (Scopus)

A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood

Li, Z., Snieder, H., Harshfield, G. A., Treiber, F. A. & Wang, X., Aug 12 2009, In : Hypertension Research. 32, 5, p. 404-410 7 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Blood Pressure
Reading
Ambulatory Blood Pressure Monitoring
African Americans
83 Citations (Scopus)

A longitudinal study in youth of heart rate variability at rest and in response to stress

Li, Z., Snieder, H., Su, S., Ding, X., Thayer, J. F., Treiber, F. A. & Wang, X., Sep 1 2009, In : International Journal of Psychophysiology. 73, 3, p. 212-217 6 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Heart Rate
African Americans
Sex Characteristics
Young Adult
26 Citations (Scopus)

Genetic influences on daytime and night-time blood pressure: Similarities and differences

Wang, X., Ding, X., Su, S., Yan, W., Harshfield, G. A., Treiber, F. & Snieder, H., Dec 1 2009, In : Journal of hypertension. 27, 12, p. 2358-2364 7 p.

Research output: Contribution to journalArticle

Blood Pressure
Genes
Sex Characteristics
African Americans
44 Citations (Scopus)

Genetic influences on heart rate variability at rest and during stress

Wang, X., Ding, X., Su, S., Li, Z., Riese, H., Thayer, J. F., Treiber, F. & Snieder, H., May 1 2009, In : Psychophysiology. 46, 3, p. 458-465 8 p.

Research output: Contribution to journalArticle

Heart Rate
Genes
African Americans
20 Citations (Scopus)

Heritability of insulin sensitivity and lipid profile depend on BMI: Evidence for gene-obesity interaction

Wang, X., Ding, X., Su, S., Spector, T. D., Mangino, M., Iliadou, A. & Snieder, H., Dec 1 2009, In : Diabetologia. 52, 12, p. 2578-2584 7 p.

Research output: Contribution to journalArticle

Insulin Resistance
Obesity
Lipids
Triglycerides
Genes
12 Citations (Scopus)

Stress-induced sodium excretion a new intermediate phenotype to study the early genetic etiology of hypertension?

Ge, D., Su, S., Zhu, H., Dong, Y., Wang, X., Harshfield, G. A., Treiber, F. A. & Snieder, H., Feb 1 2009, In : Hypertension. 53, 2, p. 262-269 8 p.

Research output: Contribution to journalArticle

Sodium
Hypertension
Phenotype
Dizygotic Twins
Natriuresis
2008
3 Citations (Scopus)

5. Role of gene-stress interactions in gene-finding studies

Snieder, H., Wang, X., Lagou, V., Penninx, B. W. J. H., Riese, H. & Hartman, C. A., Nov 19 2008, Genetic Effects on Environmental Vulnerability to Disease. p. 71-82 12 p. (Novartis Foundation Symposium; vol. 293).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Genes
Genome-Wide Association Study
Single Nucleotide Polymorphism
Endophenotypes
Gene-Environment Interaction
58 Citations (Scopus)

Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity

Kyriakou, T., Collins, L. J., Spencer-Jones, N. J., Malcolm, C., Wang, X., Snieder, H., Swaminathan, R., Burling, K. A., Hart, D. J., Spector, T. D. & O'Dell, S. D., Aug 1 2008, In : Journal of Human Genetics. 53, 8, p. 718-727 10 p.

Research output: Contribution to journalArticle

Adiponectin
Haplotypes
Single Nucleotide Polymorphism
Serum
Population
16 Citations (Scopus)

Prostasin: A possible candidate gene for human hypertension

Zhu, H., Guo, D., Li, K., Yan, W., Tan, Y., Wang, X., Treiber, F. A., Chao, J., Snieder, H. & Dong, Y., Sep 1 2008, In : American journal of hypertension. 21, 9, p. 1028-1033 6 p.

Research output: Contribution to journalArticle

Genotype
Hypertension
Single Nucleotide Polymorphism
Genes
Blood Pressure
4 Citations (Scopus)

Role of Gene-Stress Interactions in Gene-Finding Studies

Snieder, H., Wang, X., Lagou, V., Penninx, B. W. J. H., Riese, H. & Hartman, C. A., Aug 12 2008, Genetic Effects on Environmental Vulnerability to Disease. wiley, p. 71-82 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genes
Genome-Wide Association Study
Single Nucleotide Polymorphism
Endophenotypes
Gene-Environment Interaction
8 Citations (Scopus)

TUB is a candidate gene for late-onset obesity in women

Snieder, H., Wang, X., Shiri-Sverdlov, R., Van Vliet-Ostaptchouk, J. V., Hofker, M. H., Perks, U., Spector, T. D. & O'Dell, S. D., Jan 1 2008, In : Diabetologia. 51, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Abdominal Obesity
Single Nucleotide Polymorphism
Obesity
Genes
Waist Circumference
25 Citations (Scopus)

Waist circumference cutoff points in school-aged Chinese Han and Uygur children

Yan, W., Yao, H., Dai, J., Cui, J., Chen, Y., Yang, X., Harshfield, G. A. & Wang, X., Jul 1 2008, In : Obesity. 16, 7, p. 1687-1692 6 p.

Research output: Contribution to journalArticle

Waist Circumference
Weights and Measures
Age Distribution
Adiposity
Fasting
2007
6 Citations (Scopus)

Common STAT3 variants are not associated with obesity or insulin resistance in female twins

Jamshidi, Y., Kyriakou, T., Gooljar, S. B., Collins, L. J., Lane, C. A., Snieder, H., Wang, X., Spector, T. D. & O'Dell, S. D., Jul 1 2007, In : Obesity. 15, 7, p. 1634-1639 6 p.

Research output: Contribution to journalArticle

Insulin Resistance
Obesity
Single Nucleotide Polymorphism
Homeostasis
Animal Models
28 Citations (Scopus)

Heritability of Arterial Stiffness in Black and White American Youth and Young Adults

Ge, D., Young, T. W., Wang, X., Kapuku, K. G., Treiber, F. A. & Snieder, H., Oct 1 2007, In : American Journal of Hypertension. 20, 10, p. 1065-1072 8 p.

Research output: Contribution to journalArticle

Vascular Stiffness
Pulse Wave Analysis
Young Adult
Blood Pressure
Foot
15 Citations (Scopus)

SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women

Jamshidi, Y., Gooljar, S. B., Snieder, H., Wang, X., Ge, D., Swaminathan, R., Spector, T. D. & O'Dell, S. D., Oct 1 2007, In : Atherosclerosis. 194, 2, p. e26-e33

Research output: Contribution to journalArticle

Apolipoproteins B
Phosphatidylinositol 3-Kinases
LDL Cholesterol
Single Nucleotide Polymorphism
Serum
2006
14 Citations (Scopus)

Common polymorphisms in SOCS3 are not associated with body weight, insulin sensitivity or lipid profile in normal female twins

Jamshidi, Y., Snieder, H., Wang, X., Spector, T. D., Carter, N. D. & O'Dell, S. D., Feb 1 2006, In : Diabetologia. 49, 2, p. 306-310 5 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Insulin Resistance
Body Weight
Lipids
Gene Frequency
22 Citations (Scopus)

Effects of angiotensinogen and angiotensin II type I receptor genes on blood pressure and left ventricular mass trajectories in multiethnic youth

Wang, X., Zhu, H., Dong, Y., Treiber, F. A. & Snieder, H., Jun 1 2006, In : Twin Research and Human Genetics. 9, 3, p. 393-402 10 p.

Research output: Contribution to journalReview article

Angiotensin I
Angiotensinogen
Angiotensin Receptors
Haplotypes
Blood Pressure
15 Citations (Scopus)

Effects of Dopamine Receptor Type 1 and Gs Protein α Subunit Gene Polymorphisms on Blood Pressure at Rest and in Response to Stress

Lu, Y., Zhu, H., Wang, X., Snieder, H., Huang, Y., Harshfield, G. A., Treiber, F. A. & Dong, Y., Aug 1 2006, In : American Journal of Hypertension. 19, 8, p. 832-836 5 p.

Research output: Contribution to journalArticle

Dopamine Receptors
Protein Subunits
Blood Pressure
Genes
Alleles
Lipids
Genes
hydroquinone
100 Citations (Scopus)

Ethnic and gender differences in ambulatory blood pressure trajectories: Results from a 15-year longitudinal study in youth and young adults

Wang, X., Poole, J. C., Treiber, F. A., Harshfield, G. A., Hanevold, C. D. & Snieder, H., Dec 1 2006, In : Circulation. 114, 25, p. 2780-2787 8 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Young Adult
Blood Pressure
African Americans
Cross-Sectional Studies
5 Citations (Scopus)

Ethnic differences in heart rate variability: Does ultralow-frequency heart rate variability really measure autonomic tone?

Thayer, J. F., Wang, X. & Snieder, H., Sep 1 2006, In : American Heart Journal. 152, 3

Research output: Contribution to journalLetter

Autonomic Nervous System
Ethnic Groups
African Americans
Research Design
Heart Rate
15 Citations (Scopus)

Phosphatidylinositol 3-kinase p85α regulatory subunit gene PIK3R1 haplotype is associated with body fat and serum leptin in a female twin population

Jamshidi, Y., Snieder, H., Wang, X., Pavitt, M. J., Spector, T. D., Carter, N. D. & O'Dell, S. D., Nov 1 2006, In : Diabetologia. 49, 11, p. 2659-2667 9 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Regulator Genes
Leptin
Haplotypes
Adipose Tissue
22 Citations (Scopus)

Plasminogen activator inhibitor-1 gene selection of tagging single nucleotide polymorphisms and association with coronary heart disease

Su, S., Chen, S., Zhao, J., Huang, J., Wang, X., Chen, R. & Gu, D., Apr 1 2006, In : Arteriosclerosis, thrombosis, and vascular biology. 26, 4, p. 948-954 7 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Single Nucleotide Polymorphism
Coronary Disease
Haplotypes
Alleles
22 Citations (Scopus)

The Georgia Cardiovascular Twin Study: Influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes

Ge, D., Dong, Y., Wang, X., Treiber, F. A. & Snieder, H., Dec 1 2006, In : Twin Research and Human Genetics. 9, 6, p. 965-970 6 p.

Research output: Contribution to journalReview article

Twin Studies
Genetic Predisposition to Disease
Type 2 Diabetes Mellitus
Cardiovascular Diseases
Longitudinal Studies
20 Citations (Scopus)

The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins

Zhu, H., Lu, Y., Wang, X., Treiber, F. A., Harshfield, G. A., Snieder, H. & Dong, Y., Jan 1 2006, In : American journal of hypertension. 19, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinase 4
Haplotypes
Blood Pressure
Genes
Homozygote
24 Citations (Scopus)

The G protein-coupled receptor kinase 4 gene modulates stress-induced sodium excretion in black normotensive adolescents

Zhu, H., Lu, Y., Wang, X., Snieder, H., Treiber, F. A., Harshfield, G. A. & Dong, Y., Oct 1 2006, In : Pediatric research. 60, 4, p. 440-442 3 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinase 4
Sodium
Genes
Blood Pressure
Video Games
8 Citations (Scopus)

Update on G-protein polymorphisms in hypertension

Zhu, H., Wang, X., Lu, Y., Poola, J., Momin, Z., Harshfield, G. A., Snieder, H. & Dong, Y., Apr 1 2006, In : Current Hypertension Reports. 8, 1, p. 23-29 7 p.

Research output: Contribution to journalReview article

GTP-Binding Proteins
Hypertension
Genes
Pertussis Toxin
Protein Subunits
11 Citations (Scopus)

Waist-to-height ratio and BMI predict different cardiovascular risk factors in Chinese children [6]

Yan, W., Wang, X., Yao, H., Dai, J., Zheng, Y., Yang, X., Yibulayin, X. & Cui, J., Dec 1 2006, In : Diabetes Care. 29, 12, p. 2760-2761 2 p.

Research output: Contribution to journalLetter

Body Size
China
Body Mass Index
Cardiovascular Diseases
Waist-Height Ratio
2005

Association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese

Wang, X., Fan, Z. J., Huang, J. F., Su, S., Zhao, J. G. & Gu, D. F., Jul 1 2005, In : Acta Genetica Sinica. 32, 7, p. 675-681 7 p.

Research output: Contribution to journalArticle

Multigene Family
Coronary Disease
Alleles
Haplotypes
Population
74 Citations (Scopus)

Ethnic differences and heritability of heart rate variability in African- and European American youth

Wang, X., Thayer, J. F., Treiber, F. & Snieder, H., Oct 15 2005, In : American Journal of Cardiology. 96, 8, p. 1166-1172 7 p.

Research output: Contribution to journalArticle

African Americans
Heart Rate
Supine Position
11 Citations (Scopus)

Genetic and environmental determinants of lipid profile in Black and White youth: A study of four candidate genes

Davis, C. L., Wang, X., Sneider, H. & Treiber, F. A., Sep 1 2005, In : Ethnicity and Disease. 15, 4, p. 568-577 10 p.

Research output: Contribution to journalArticle

Apolipoproteins B
Alleles
Lipids
LDL Receptors
Peroxisome Proliferator-Activated Receptors
29 Citations (Scopus)

Genetic and environmental influences on anger expression, John Henryism, and stressful life events: The Georgia cardiovascular twin study

Wang, X., Trivedi, R., Treiber, F. & Snieder, H., Jan 1 2005, In : Psychosomatic Medicine. 67, 1, p. 16-23 8 p.

Research output: Contribution to journalArticle

Twin Studies
Anger
Individuality
Sex Characteristics
African Americans
14 Citations (Scopus)

Heritabilities of lipids in young European American and African American twins

Iliadou, A., Snieder, H., Wang, X., Treiber, F. A. & Davis, C. L., Oct 1 2005, In : Twin Research and Human Genetics. 8, 5, p. 492-498 7 p.

Research output: Contribution to journalArticle

African Americans
Lipids
Twin Studies
HDL Lipoproteins
LDL Lipoproteins
24 Citations (Scopus)

Influence of the eNOS gene on development of blood pressure and left ventricular mass: Longitudinal findings in multiethnic youth

Zhu, H., Wang, X., Dong, Y., Treiber, F. A. & Snieder, H., Jan 1 2005, In : Pharmacogenetics and Genomics. 15, 9, p. 669-675 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Haplotypes
Blood Pressure
Introns
Genes
18 Citations (Scopus)

Paraoxonase gene cluster variations associated with coronary heart disease in Chinese Han women

Su, S., Chen, J. H., Huang, J. F., Wang, X., Zhao, J. G., Shen, Y., Qiang, B. Q. & Gu, D. F., Jul 20 2005, In : Chinese Medical Journal. 118, 14, p. 1167-1174 8 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Multigene Family
Haplotypes
Coronary Disease
LDL Lipoproteins

Polymorphisms screening of PON gene cluster

Wang, X., Fan, Z. J., Huang, J. F., Su, S., Zhao, J. G. & Gu, D. F., Jan 1 2005, In : Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji. 27, 4, p. 539-543 5 p.

Research output: Contribution to journalArticle

Multigene Family
Population
Genetic Promoter Regions
Genes
Transcription Initiation Site
19 Citations (Scopus)

Proopiomelanocortin gene variants are associated with serum leptin and body fat in a normal female population

Chen, Y., Snieder, H., Wang, X., Kaviya, B., McCaffrey, C., Spector, T. D., Carter, N. D. & O'Dell, S. D., Jun 1 2005, In : European Journal of Human Genetics. 13, 6, p. 772-780 9 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
Leptin
Adipose Tissue
Single Nucleotide Polymorphism
Fats
35 Citations (Scopus)

Protein tyrosine phosphatase-1B gene PTPN1: Selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population

Spencer-Jones, N. J., Wang, X., Snieder, H., Spector, T. D., Carter, N. D. & O'Dell, S. D., Nov 1 2005, In : Diabetes. 54, 11, p. 3296-3304 9 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Single Nucleotide Polymorphism
Insulin Resistance
Adipose Tissue
Haplotypes
2004
17 Citations (Scopus)

Angiotensin II type I receptor gene and myocardial infarction: Tagging SNPs and haplotype based association study. The Beijing atherosclerosis study

Su, S., Chen, J., Zhao, J., Huang, J., Wang, X., Chen, R. & Gu, D., Oct 1 2004, In : Pharmacogenetics. 14, 10, p. 673-681 9 p.

Research output: Contribution to journalArticle

Angiotensin I
Angiotensin Receptors
Haplotypes
Single Nucleotide Polymorphism
Atherosclerosis
27 Citations (Scopus)

Endothelin-1 gene and progression of blood pressure and left ventricular mass: Longitudinal findings in youth

Dong, Y., Wang, X., Zhu, H., Treiber, F. A. & Snieder, H., Dec 1 2004, In : Hypertension. 44, 6, p. 884-890 7 p.

Research output: Contribution to journalArticle

Endothelin-1
Alleles
Haplotypes
Blood Pressure
Left Ventricular Hypertrophy
11 Citations (Scopus)

Genetic and environmental factors associated with plasma paraoxonase activity in healthy Chinese.

Wang, X., Huang, J., Fan, Z., Su, S., Zhao, J., Shen, Y., Qiang, B. & Gu, D., Jan 1 2004, In : International journal of molecular medicine. 13, 3, p. 445-450 6 p.

Research output: Contribution to journalArticle

Aryldialkylphosphatase
Smoking
Drinking
Alcohol Drinking
Population
78 Citations (Scopus)

Obesity reveals an association between blood pressure and the G-protein β3-subunit gene: A study of female dizygotic twins

Dong, Y., Zhu, H., Wang, X., Dalageorgou, C., Carter, N., Spector, T. D. & Snieder, H., Jul 1 2004, In : Pharmacogenetics. 14, 7, p. 419-427 9 p.

Research output: Contribution to journalArticle

Dizygotic Twins
Protein Subunits
GTP-Binding Proteins
Obesity
Blood Pressure
14 Citations (Scopus)

Thrombospondin-4 A387P polymorphism is not associated with coronary artery disease and myocardial infarction in the Chinese Han population

Zhou, X., Huang, J., Chen, J., Zhao, J., Yang, W., Wang, X. & Gu, D., May 1 2004, In : Clinical Science. 106, 5, p. 495-500 6 p.

Research output: Contribution to journalArticle

Myocardial Infarction
Coronary Artery Disease
Population
Restriction Fragment Length Polymorphisms
Polymerase Chain Reaction
2003
97 Citations (Scopus)

Extensive association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese Han population

Wang, X., Fan, Z., Huang, J., Su, S., Yu, Q., Zhao, J., Hui, R., Yao, Z., Shen, Y., Qiang, B. & Gu, D., Feb 1 2003, In : Arteriosclerosis, thrombosis, and vascular biology. 23, 2, p. 328-334 7 p.

Research output: Contribution to journalArticle

Multigene Family
Coronary Disease
Alleles
Haplotypes
Population
8 Citations (Scopus)

Linkage analysis of 2q14-q23 and 5q32 with blood pressure quantitative traits in Chinese sib pairs

Ge, D., Yang, W., Huang, J., Yao, C., Xu, X., Gan, W., Zhao, J., Liu, D., Wang, X., Duan, X., Hui, R., Shen, Y., Yao, Z., Qiang, B. & Gu, D., Feb 1 2003, In : Journal of hypertension. 21, 2, p. 305-310 6 p.

Research output: Contribution to journalArticle

Blood Pressure
Microsatellite Repeats
Adrenergic Receptors
Alleles
Hypertension
2002
52 Citations (Scopus)

Factor V gene G1691A mutation, prothrombin gene G20210A mutation, and MTHFR gene C677T mutation are not risk factors for pulmonary thromboembolism in Chinese population

Lu, Y., Zhao, Y., Liu, G., Wang, X., Liu, Z., Chen, B. & Hui, R., Apr 1 2002, In : Thrombosis Research. 106, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

Methylenetetrahydrofolate Reductase (NADPH2)
Prothrombin
Pulmonary Embolism
Mutation
Population