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Research Output 1989 2019

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Article
1989
5 Citations (Scopus)

Relation of TXA2 and PGI2 to the difference in hypoxic pulmonary vasoconstriction between different strains of rats

Su, Y. & Xian-rong, J., Sep 1 1989, In : Journal of Tongji Medical University. 9, 3, p. 148-152 5 p.

Research output: Contribution to journalArticle

Epoprostenol
Vasoconstriction
Rats
Wistar Rats
Lung
1990
6 Citations (Scopus)

Strain difference in pulmonary vascular responsiveness to hypoxia in rats

Xian-rong, J., Ming, F., Zhi-qiang, W., Su, Y., Guang-tian, Y., Han-bo, H., Ye-ping, Z., Chang-jian, F., Yao-xian, D. & Di-xun, W., Jan 1 1990, In : Journal of Tongji Medical University. 10, 3, p. 134-140 7 p.

Research output: Contribution to journalArticle

Blood Vessels
Rats
Lung
Vasoconstriction
Leukotrienes
1991
1 Citation (Scopus)
Endothelial cells
Epoprostenol
Tobacco Products
Pulmonary Artery
Platelet Activating Factor
1993
1 Citation (Scopus)
Endothelial cells
Half-Life
Endothelial Cells
Aorta
Lung
1995
35 Citations (Scopus)
citrulline
Citrulline
pulmonary artery
Pulmonary Artery
endothelial cells
175 Citations (Scopus)

The formation of nitric oxide donors from peroxynitrite

Moro, M. Á., Darley‐Usmar, V. M., Lizasoain, I., Su, Y., Knowles, R. G., Moncada, S. & Radomski, M. W., Oct 1995, In : British Journal of Pharmacology. 116, 3, p. 1999-2004 6 p.

Research output: Contribution to journalArticle

Peroxynitrous Acid
Nitric Oxide Donors
Nitric Oxide
Glucose
Oxyhemoglobins
1996
13 Citations (Scopus)

Acute hypoxia increases intracellular L-arginine content in cultured porcine pulmonary artery enclothelial cells

Su, Y. & Block, E. R., May 1996, In : Journal of Cellular Physiology. 167, 2, p. 349-353 5 p.

Research output: Contribution to journalArticle

Pulmonary Artery
Arginine
Swine
Calpain
Endothelial cells
401 Citations (Scopus)

cGMP mediates the vascular and platelet actions of nitric oxide: Confirmation using an inhibitor of the soluble guanylyl cyclase

Moro, M. A., Russell, R. J., Cellek, S., Lizasoain, I., Su, Y., Darley-Usmar, V. M., Radomski, M. W. & Moncada, S., Feb 20 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 4, p. 1480-1485 6 p.

Research output: Contribution to journalArticle

Blood Vessels
Nitric Oxide
Blood Platelets
Vascular Smooth Muscle
Vasodilator Agents
1997
8 Citations (Scopus)
Argininosuccinate Synthase
Endotoxins
Endothelial Cells
Lung
Pulmonary Artery
11 Citations (Scopus)

Substrate inhibition of nitric oxide synthase in pulmonary artery endothelial cells in culture

Su, Y., Couch, M. & Block, E. R., Jan 1 1997, In : Nitric Oxide - Biology and Chemistry. 1, 6, p. 469-475 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Cell culture
Nitric Oxide Synthase
Pulmonary Artery
Arginine
1998
260 Citations (Scopus)

Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells

Su, Y., Han, W., Giraldo, C., De Li, Y. & Block, E. R., Jan 1 1998, In : American journal of respiratory cell and molecular biology. 19, 5, p. 819-825 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Nitric Oxide Synthase
Smoke
Tobacco Products
Pulmonary Artery
2000
9 Citations (Scopus)

Phenylarsine oxide inhibits nitric oxide synthase in pulmonary artery endothelial cells

Su, Y. & Block, E. R., Jan 15 2000, In : Free Radical Biology and Medicine. 28, 2, p. 167-173 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Nitric Oxide Synthase
Pulmonary Artery
Tyrosine
Endothelial Cells
63 Citations (Scopus)
Calpain
Nitric Oxide Synthase Type III
Nitric Oxide Synthase
Endothelial Cells
HSP90 Heat-Shock Proteins
2003
70 Citations (Scopus)

Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP)

Wang, C. Y., Shi, J. D., Yang, P., Kumar, P. G., Li, Q. Z., Run, Q. G., Su, Y., Scott, H. S., Kao, K. J. & She, J-X., Mar 13 2003, In : Gene. 306, 1-2, p. 37-44 8 p.

Research output: Contribution to journalArticle

Molecular Cloning
Amino Acids
Genes
Complementary DNA
Proteins
82 Citations (Scopus)

Regulation of endothelial nitric oxide synthase by the actin cytoskeleton

Su, Y., Edwards-Bennett, S., Bubb, M. R. & Block, E. R., Jun 1 2003, In : American Journal of Physiology - Cell Physiology. 284, 6 53-6

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Actin Cytoskeleton
Actins
Endothelial cells
Pulmonary Artery
2004
45 Citations (Scopus)

Cigarette smoke extract inhibits angiogenesis of pulmonary artery endothelial cells: The role of calpain

Su, Y., Cao, W., Han, Z. & Block, E. R., Oct 1 2004, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 287, 4 31-4, p. L794-L800

Research output: Contribution to journalArticle

Calpain
Smoke
Tobacco Products
Pulmonary Artery
Endothelial Cells
2005
10 Citations (Scopus)

Involvement of calpain-calpastatin in cigarette smoke-induced inhibition of lung endothelial nitric oxide synthase

Cui, Z., Han, Z., Li, Z., Hu, H., Patel, J. M., Antony, V., Block, E. R. & Su, Y., Nov 1 2005, In : American journal of respiratory cell and molecular biology. 33, 5, p. 513-520 8 p.

Research output: Contribution to journalArticle

Calpain
Nitric Oxide Synthase Type III
Smoke
Tobacco Products
Lung
2006
62 Citations (Scopus)

Calpain-2 regulation of VEGF-mediated angiogenesis

Su, Y., Cui, Z., Li, Z. & Block, E. R., Jul 1 2006, In : FASEB Journal. 20, 9, p. 1443-1451 9 p.

Research output: Contribution to journalArticle

calpain
Calpain
vascular endothelial growth factors
angiogenesis
Vascular Endothelial Growth Factor A
26 Citations (Scopus)

Growth and density-dependent regulation of NO synthase by the actin cytoskeleton in pulmonary artery endothelial cells

Kondrikov, D., Han, H. R., Block, E. R. & Su, Y., Jan 1 2006, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 290, 1, p. L41-L50

Research output: Contribution to journalArticle

Actin Cytoskeleton
Nitric Oxide Synthase
Pulmonary Artery
Actins
Endothelial Cells
13 Citations (Scopus)

Use of recombinant calpain-2 siRNA adenovirus to assess calpain-2 modulation of lung endothelial cell migration and proliferation

Qiu, K., Su, Y. & Block, E. R., Nov 1 2006, In : Molecular and Cellular Biochemistry. 292, 1-2, p. 69-78 10 p.

Research output: Contribution to journalArticle

Calpain
Endothelial cells
Adenoviridae
Small Interfering RNA
Cell Movement
2007
39 Citations (Scopus)

Talc mediates angiostasis in malignant pleural effusions via endostatin induction

Najmunnisa, N., Mohammed, K. A., Brown, S., Su, Y., Sriram, P. S., Moudgil, B., Loddenkemper, R. & Antony, V. B., Apr 1 2007, In : European Respiratory Journal. 29, 4, p. 761-769 9 p.

Research output: Contribution to journalArticle

Endostatins
Malignant Pleural Effusion
Talc
Insufflation
Pleural Diseases
2009
26 Citations (Scopus)

α-Defensins increase lung fibroblast proliferation and collagen synthesis via the β-catenin signaling pathway

Han, W., Wang, W., Mohammed, K. A. & Su, Y., Nov 1 2009, In : FEBS Journal. 276, 22, p. 6603-6614 12 p.

Research output: Contribution to journalArticle

Defensins
Catenins
Fibroblasts
Collagen
Lung
2010
17 Citations (Scopus)

eNOS-β-actin interaction contributes to increased peroxynitrite formation during hyperoxia in pulmonary artery endothelial cells and mouse lungs

Kondrikov, D., Elms, S., Fulton, D. & Su, Y., Nov 12 2010, In : Journal of Biological Chemistry. 285, 46, p. 35479-35487 9 p.

Research output: Contribution to journalArticle

Hyperoxia
Peroxynitrous Acid
Endothelial cells
Nitric Oxide Synthase
Pulmonary Artery
24 Citations (Scopus)

β-actin association with endothelial nitric-oxide synthase modulates nitric oxide and superoxide generation from the enzyme

Kondrikov, D., Fonseca, F. V., Elms, S., Fulton, D., Black, S. M., Block, E. R. & Su, Y., Feb 12 2010, In : Journal of Biological Chemistry. 285, 7, p. 4319-4327 9 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Superoxides
Actins
Nitric Oxide
Enzymes
2011
68 Citations (Scopus)

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease

Ma, W., Han, W., Greer, P. A., Tuder, R. M., Toque, H. A., Wang, K. K. W., Caldwell, R. W. & Su, Y., Nov 1 2011, In : Journal of Clinical Investigation. 121, 11, p. 4548-4566 19 p.

Research output: Contribution to journalArticle

Calpain
Pulmonary Hypertension
Rodentia
Lung
Epidermal Growth Factor
12 Citations (Scopus)

Collagen IV contributes to nitric oxide-induced angiogenesis of lung endothelial cells

Wang, H. & Su, Y., May 1 2011, In : American Journal of Physiology - Cell Physiology. 300, 5, p. C979-C988

Research output: Contribution to journalArticle

Nitric Oxide
Collagen
Endothelial Cells
Lung
Integrins
37 Citations (Scopus)
Rhabdomyolysis
Heme Oxygenase-1
Granulocyte Colony-Stimulating Factor
Acute Kidney Injury
Heme
62 Citations (Scopus)

Hydrogen sulfide ameliorates tobacco smoke-induced oxidative stress and emphysema in mice

Han, W., Dong, Z., Dimitropoulou, C. & Su, Y., Oct 15 2011, In : Antioxidants and Redox Signaling. 15, 8, p. 2121-2134 14 p.

Research output: Contribution to journalArticle

Hydrogen Sulfide
Oxidative stress
Tobacco
Emphysema
Smoke
34 Citations (Scopus)

Reactive oxygen species-dependent RhoA activation mediates collagen synthesis in hyperoxic lung fibrosis

Kondrikov, D., Caldwell, R. B., Dong, Z. & Su, Y., Jun 1 2011, In : Free Radical Biology and Medicine. 50, 11, p. 1689-1698 10 p.

Research output: Contribution to journalArticle

Fibroblasts
Reactive Oxygen Species
Fibrosis
Collagen
Chemical activation
2012
233 Citations (Scopus)

Autophagy in proximal tubules protects against acute kidney injury

Jiang, M., Wei, Q., Dong, G., Komatsu, M., Su, Y. & Dong, Z., Dec 2 2012, In : Kidney International. 82, 12, p. 1271-1283 13 p.

Research output: Contribution to journalArticle

Autophagy
Acute Kidney Injury
Cisplatin
Knockout Mice
Kidney
17 Citations (Scopus)

Calpain 2-dependent IκBα degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts

Fenouille, N., Grosso, S., Su, Y., Didier, M., Pontier-Bres, R., Imbert, V., Czerucka, D., Caroli-Bosc, F. X., Peyron, J. F. & Lagadec, P., May 1 2012, In : Journal of Pathology. 227, 1, p. 118-129 12 p.

Research output: Contribution to journalArticle

irinotecan
Calpain
Heterografts
Colorectal Neoplasms
Annexin A2
2013
19 Citations (Scopus)

Akita spontaneously type 1 diabetic mice exhibit elevated vascular arginase and impaired vascular endothelial and nitrergic function

Toque, H. A., Nunes, K. P., Yao, L., Xu, Z., Kondrikov, D., Su, Y., Webb, R. C., Caldwell, R. B. & Caldwell, R. W., Jan 1 2013, In : PloS one. 8, 8, p. e72277

Research output: Contribution to journalArticle

Arginase
arginase
blood vessels
Blood Vessels
Medical problems
10 Citations (Scopus)

SUMO1 regulates endothelial function by modulating the overall signals in favor of angiogenesis and homeostatic responses

Yang, P., Zhang, Y., Xu, J., Zhang, S., Yu, Q., Pang, J., Rao, X., Kuczma, M., Marrero, M. B., Fulton, D. J., Kraj, P., Su, Y. & Wang, C. Y., Jan 1 2013, In : American Journal of Translational Research. 5, 4, p. 427-440 14 p.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin
Endothelial cells
Swine
Endothelial Cells
22 Citations (Scopus)

The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis

Ni, J., Dong, Z., Han, W., Kondrikov, D. Y. & Su, Y., Apr 25 2013, In : Free Radical Biology and Medicine. 61, p. 26-39 14 p.

Research output: Contribution to journalArticle

Myofibroblasts
Hyperoxia
Cytoskeleton
Actin Cytoskeleton
Actins
2014
41 Citations (Scopus)

Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species

Chen, F., Barman, S., Yu, Y., Haigh, S., Wang, Y., Dou, H., Bagi, Z., Han, W., Su, Y. & Fulton, D. J. R., Aug 2014, In : Free Radical Biology and Medicine. 73, p. 201-213 13 p.

Research output: Contribution to journalArticle

Caveolin 1
NADPH Oxidase
Reactive Oxygen Species
Pulmonary Artery
Pulmonary Hypertension
6 Citations (Scopus)

Cotinine concentration in serum correlates with tobacco smoke-induced emphysema in mice

Xu, X., Su, Y. & Fan, Z. H., Jan 27 2014, In : Scientific reports. 4, 3864.

Research output: Contribution to journalArticle

Cotinine
Emphysema
Smoke
Tobacco
Serum
6 Citations (Scopus)

Dissociation of FK506-binding protein 12.6 kD from ryanodine receptor in bronchial smooth muscle cells in airway hyperresponsiveness in asthma

Du, Y., Zhao, J., Li, X., Jin, S., Ma, W. L., Mu, Q., Xu, S., Yang, J., Rao, S., Zhu, L., Xin, J., Cai, P. C., Su, Y. & Ye, H., Feb 1 2014, In : American journal of respiratory cell and molecular biology. 50, 2, p. 398-408 11 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Ryanodine Receptor Calcium Release Channel
Smooth Muscle Myocytes
Muscle
Asthma
82 Citations (Scopus)

Endothelial PFKFB3 plays a critical role in angiogenesis

Xu, Y., An, X., Guo, X., Habtetsion, T. G., Wang, Y., Xu, X., Kandala, S., Li, Q., Li, H., Zhang, C., Caldwell, R. B., Fulton, D. J., Su, Y., Hoda, MD. N., Zhou, G., Wu, C. & Huo, Y., Jun 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 6, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Protein Isoforms
Glycolysis
Endothelial Cells
Lactic Acid
31 Citations (Scopus)

Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase

Sun, X., Kumar, S., Sharma, S., Aggarwal, S., Lu, Q., Gross, C., Rafikova, O., Lee, S. G., Dasarathy, S., Hou, Y., Meadows, M. L., Han, W., Su, Y., Fineman, J. R. & Black, S. M., Jun 2014, In : American journal of respiratory cell and molecular biology. 50, 6, p. 1084-1095 12 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Endothelial cells
Endothelin-1
Pulmonary Hypertension
Endothelial Cells
16 Citations (Scopus)

Increasing muscle mass improves vascular function in obese (DB/DB) Mice

Qiu, S., Mintz, J. D., Salet, C. D., Han, W., Giannis, A., Chen, F., Yu, Y., Su, Y., Fulton, D. J. & Stepp, D. W., Jan 1 2014, In : Journal of the American Heart Association. 3, 3, 000854.

Research output: Contribution to journalArticle

Myostatin
Obese Mice
Blood Vessels
Vasodilation
Muscles
65 Citations (Scopus)

NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling

Barman, S. A., Chen, F., Su, Y., Dimitropoulou, C., Wang, Y., Catravas, J. D., Han, W., Orfi, L., Szantai-Kis, C., Keri, G., Szabadkai, I., Barabutis, N., Rafikova, O., Rafikov, R., Black, S. M., Jonigk, D., Giannis, A., Asmis, R., Stepp, D. W., Ramesh, G. & 1 others, Fulton, D. J., Aug 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 8, p. 1704-1715 12 p.

Research output: Contribution to journalArticle

Adventitia
NADPH Oxidase
Pulmonary Artery
Pulmonary Hypertension
Fibroblasts
7 Citations (Scopus)

Novel peptide for attenuation of hyperoxia-induced disruption of lung endothelial barrier and pulmonary edema via modulating peroxynitrite formation

Kondrikov, D., Gross, C., Black, S. M. & Su, Y., Nov 28 2014, In : Journal of Biological Chemistry. 289, 48, p. 33355-33363 9 p.

Research output: Contribution to journalArticle

Hyperoxia
Peroxynitrous Acid
Pulmonary Edema
Apoptosis
Actins
16 Citations (Scopus)

Regulation of endothelial nitric oxide synthase activity by protein-protein interaction

Su, Y., Jan 1 2014, In : Current Pharmaceutical Design. 20, 22, p. 3514-3520 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Proteins
Nitric Oxide Synthase
Dynamin II
Cationic Amino Acid Transporter 1
2015
25 Citations (Scopus)

Bleomycin induced epithelial-mesenchymal transition (EMT) in pleural mesothelial cells

Chen, L. J., Ye, H., Zhang, Q., Li, F. Z., Song, L. J., Yang, J., Mu, Q., Rao, S. S., Cai, P. C., Xiang, F., Zhang, J. C., Su, Y., Xin, J. B. & Ma, W. L., Mar 1 2015, In : Toxicology and Applied Pharmacology. 283, 2, p. 75-82 8 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Bleomycin
Idiopathic Pulmonary Fibrosis
Fibrosis
Collagen
4 Citations (Scopus)

CAT-1 as a novel CAM stabilizes endothelial integrity and mediates the protective actions of l-Arg via a NO-independent mechanism

Guo, L., Tian, S., Chen, Y., Mao, Y., Cui, S., Hu, A., Zhang, J., Xia, S. L., Su, Y., Du, J., Block, E. R., Wang, X. L. & Cui, Z., Oct 1 2015, In : Journal of molecular and cellular cardiology. 87, p. 180-191 12 p.

Research output: Contribution to journalArticle

Cationic Amino Acid Transporter 1
Cell Adhesion Molecules
Intercellular Junctions
Basic Amino Acid Transport Systems
Catenins
27 Citations (Scopus)

Crosstalk between calpain activation and TGF-β1 augments collagen-I synthesis in pulmonary fibrosis

Li, F. Z., Cai, P. C., Song, L. J., Zhou, L. L., Zhang, Q., Rao, S. S., Xia, Y., Xiang, F., Xin, J. B., Greer, P. A., Shi, H. Z., Su, Y., Ma, W. L. & Ye, H., Sep 1 2015, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 9, p. 1796-1804 9 p.

Research output: Contribution to journalArticle

Calpain
Pulmonary Fibrosis
Collagen
Lung
Fibroblasts
33 Citations (Scopus)

EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling

Lu, A., Zuo, C., He, Y., Chen, G., Piao, L., Zhang, J., Xiao, B., Shen, Y., Tang, J., Kong, D., Alberti, S., Chen, D., Zuo, S., Zhang, Q., Yan, S., Fei, X., Yuan, F., Zhou, B., Duan, S., Yu, Y. & 5 others, Lazarus, M., Su, Y., Breyer, R. M., Funk, C. D. & Yu, Y., Mar 2 2015, In : Journal of Clinical Investigation. 125, 3, p. 1228-1242 15 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Prostaglandins
Smooth Muscle Myocytes
Pulmonary Artery
Lung
7 Citations (Scopus)
Apoptosis Inducing Factor
hyperoxia
Hyperoxia
HSP70 Heat-Shock Proteins
caspases
57 Citations (Scopus)
Acute Kidney Injury
Hyperglycemia
Apoptosis
Kidney
Glucose
49 Citations (Scopus)

Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways

Wang, S., Livingston, M. J., Su, Y. & Dong, Z., Jan 1 2015, In : Autophagy. 11, 4, p. 607-616 10 p.

Research output: Contribution to journalArticle

Cilia
Autophagy
Proteasome Endopeptidase Complex
Kidney
Proteasome Inhibitors