Yutaka Itokazu

Senior Research Scientist

  • 2163 Citations
  • 16 h-Index
20002020

Research output per year

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Research Output

  • 2163 Citations
  • 16 h-Index
  • 28 Article
  • 3 Chapter
  • 2 Review article
  • 1 Comment/debate
2020
Open Access
2019
Open Access
2018

Gangliosides in Nerve Cell Specification

Itokazu, Y., Wang, J. & Yu, R. K., Jan 1 2018, Progress in Molecular Biology and Translational Science. Schnaar, R. L. & Lopez, P. H. H. (eds.). Elsevier B.V., p. 241-263 23 p. (Progress in Molecular Biology and Translational Science; vol. 156).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes

Kong, J. N., Zhu, Z., Itokazu, Y., Wang, G., Dinkins, M. B., Zhong, L., Lin, H. P., Elsherbini, A., Leanhart, S., Jiang, X., Qin, H., Zhi, W., Spassieva, S. D. & Bieberich, E., 2018, In : Journal of Lipid Research. 59, 3, p. 488-506 19 p.

Research output: Contribution to journalArticle

16 Scopus citations
2017

Epigenetic regulation of ganglioside expression in neural stem cells and neuronal cells

Itokazu, Y., Tsai, Y. T. & Yu, R. K., Dec 1 2017, In : Glycoconjugate Journal. 34, 6, p. 749-756 8 p.

Research output: Contribution to journalReview article

14 Scopus citations
2016

A2B5+/GFAP+ Cells of Rat Spinal Cord Share a Similar Lipid Profile with Progenitor Cells: A Comparative Lipidomic Study

Itokazu, Y., Tajima, N., Kerosuo, L., Somerharju, P., Sariola, H., Yu, R. K. & Käkelä, R., Jul 1 2016, In : Neurochemical Research. 41, 7, p. 1527-1544 18 p.

Research output: Contribution to journalArticle

5 Scopus citations

Erratum: Novel GM1 ganglioside-like peptide mimics prevent the association of cholera toxin to human intestinal epithelial in vitro

Yu, R. K., Usuki, S., Itokazu, Y. & Wu, H. C., May 1 2016, In : Glycobiology. 26, 5, p. 540 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

GM1 ganglioside is involved in epigenetic activation loci of neuronal cells

Tsai, Y. T., Itokazu, Y. & Yu, R. K., Oct 24 2016, In : Neurochemical Research. 41, 1-2, p. 107-115 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Ganglioside-dependent neural stem cell proliferation in alzheimer’s disease model mice

Koon, N. A., Itokazu, Y. & Yu, R. K., Nov 9 2015, In : ASN Neuro. 7, 6

Research output: Contribution to journalArticle

5 Scopus citations

Glycolipid Antigens in Neural Stem Cells

Itokazu, Y. & Yu, R. K., Apr 15 2015, Neural Surface Antigens: From Basic Biology Towards Biomedical Applications. Elsevier Inc., p. 91-102 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuroglycobiology: Role of glycans in neurobiology and neuroscience glycoconjugate antigens in neural stem cells

Itokazu, Y. & Yu, R. K., Jan 1 2015, Glycoscience: Biology and Medicine. Springer Japan, p. 495-504 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Novel GM1 ganglioside-like peptide mimics prevent the association of cholera toxin to human intestinal epithelial cells in vitro

Yu, R. K., Usuki, S., Itokazu, Y. & Wu, H. C., Jun 11 2015, In : Glycobiology. 26, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014
17 Scopus citations

Gill tissue lipids of salmon (Salmo salar L.) presmolts and smolts from anadromous and landlocked populations

Itokazu, Y., Käkelä, R., Piironen, J., Guan, X. L., Kiiskinen, P. & Vornanen, M., Jun 2014, In : Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology. 172, p. 39-45 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Glycolipid and glycoprotein expression during neural development

Yu, R. K. & Itokazu, Y., 2014, In : Advances in neurobiology. 9, p. 185-222 38 p.

Research output: Contribution to journalArticle

Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair

Itokazu, Y., Pagano, R. E., Schroeder, A. S., O'Grady, S. M., Limper, A. H. & Marks, D. L., May 1 2014, In : American Journal of Physiology - Cell Physiology. 306, 9, p. C819-C830

Research output: Contribution to journalArticle

29 Scopus citations
2013

Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: Expression of elevated levels of a cholinergic-specific ganglioside, GT1aα

Ariga, T., Itokazu, Y., McDonald, M. P., Hirabayashi, Y., Ando, S. & Yu, R. K., 2013, In : ASN Neuro. 5, 2, p. 141-148 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effects of amyloid β-peptides and gangliosides on mouse neural stem cells

Itokazu, Y., Kato-Negishi, M., Nakatani, Y., Ariga, T. & Yu, R. K., Oct 2013, In : Neurochemical Research. 38, 10, p. 2019-2027 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
2011

Activity of BKCa channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells

Tajima, N., Itokazu, Y., Korpi, E. R., Somerharju, P. & Käkelä, R., Feb 18 2011, In : Journal of Biological Chemistry. 286, 7, p. 5624-5638 15 p.

Research output: Contribution to journalArticle

32 Scopus citations
2010

Long-term observation of auto-cell transplantation in non-human primate reveals safety and efficiency of bone marrow stromal cell-derived Schwann cells in peripheral nerve regeneration

Wakao, S., Hayashi, T., Kitada, M., Kohama, M., Matsue, D., Teramoto, N., Ose, T., Itokazu, Y., Koshino, K., Watabe, H., Iida, H., Takamoto, T., Tabata, Y. & Dezawa, M., Jun 1 2010, In : Experimental Neurology. 223, 2, p. 537-547 11 p.

Research output: Contribution to journalArticle

85 Scopus citations

Transplantation of cultured choroid plexus epithelial cells via cerebrospinal fluid shows prominent neuroprotective effects against acute ischemic brain injury in the rat

Matsumoto, N., Taguchi, A., Kitayama, H., Watanabe, Y., Ohta, M., Yoshihara, T., Itokazu, Y., Dezawa, M., Suzuki, Y., Sugimoto, H., Noda, M. & Ide, C., Jan 29 2010, In : Neuroscience Letters. 469, 3, p. 283-288 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
2009

Committed neural progenitor cells derived from genetically modified bone marrow stromal cells ameliorate deficits in a rat model of stroke

Hayase, M., Kitada, M., Wakao, S., Itokazu, Y., Nozaki, K., Hashimoto, N., Takagi, Y. & Dezawa, M., Aug 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 8, p. 1409-1420 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Isolation and characterization of patient-derived, toxic, high mass Amyloid β-protein (Aβ) assembly from Alzheimer disease brains

Noguchi, A., Matsumura, S., Dezawa, M., Tada, M., Yanazawa, M., Ito, A., Akioka, M., Kikuchi, S., Sato, M., Noda, M., Fukunari, A., Muramatsu, S. I., Itokazu, Y., Sato, K., Takahashi, H., Teplow, D. B., Nabeshima, Y. I., Kakita, A., Imahori, K. & Hoshi, M., Nov 20 2009, In : Journal of Biological Chemistry. 284, 47, p. 32895-32905 11 p.

Research output: Contribution to journalArticle

129 Scopus citations
2007

Neuroprotective effect of bone marrow-derived mononuclear cells promoting functional recovery from spinal cord injury

Yoshihara, T., Ohta, M., Itokazu, Y., Matsumoto, N., Dezawa, M., Suzuki, Y., Taguchi, A., Watanabe, Y., Adachi, Y., Ikehara, S., Sugimoto, H. & Ide, C., Jun 2007, In : Journal of Neurotrauma. 24, 6, p. 1026-1036 11 p.

Research output: Contribution to journalArticle

56 Scopus citations

Peripheral nerve regeneration by the in vitro differentiated-human bone marrow stromal cells with Schwann cell property

Shimizu, S., Kitada, M., Ishikawa, H., Itokazu, Y., Wakao, S. & Dezawa, M., Aug 10 2007, In : Biochemical and Biophysical Research Communications. 359, 4, p. 915-920 6 p.

Research output: Contribution to journalArticle

122 Scopus citations
2006

Choroid plexus ependymal cells host neural progenitor cells in the rat

Itokazu, Y., Kitada, M., Dezawa, M., Mizoguchi, A., Matsumoto, N., Shimizu, A. & Ide, C., Jan 1 2006, In : Glia. 53, 1, p. 32-42 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Effects of vibration and hyaluronic acid on activation of three-dimensional cultured chondrocytes

Takeuchi, R., Saito, T., Ishikawa, H., Takigami, H., Dezawa, M., Ide, C., Itokazu, Y., Ikeda, M., Shiraishi, T. & Morishita, S., Jun 2006, In : Arthritis and Rheumatism. 54, 6, p. 1897-1905 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2005

Conditioned medium of the primary culture of rat choroid plexus epithelial (modified ependymal) cells enhances neurite outgrowth and survival of hippocampal neurons

Watanabe, Y., Matsumoto, N., Dezawa, M., Itokazu, Y., Yoshihara, T. & Ide, C., May 13 2005, In : Neuroscience Letters. 379, 3, p. 158-163 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Developmental biology: Bone marrow stromal cells generate muscle cells and repair muscle degeneration

Dezawa, M., Ishikawa, H., Itokazu, Y., Yoshihara, T., Hoshino, M., Takeda, S. I., Ide, C. & Nabeshima, Y. I., Jul 8 2005, In : Science. 309, 5732, p. 314-317 4 p.

Research output: Contribution to journalArticle

485 Scopus citations

Neurogenesis in the ependymal layer of the adult rat 3rd ventricle

Xu, Y., Tamamaki, N., Noda, T., Kimura, K., Itokazu, Y., Matsumoto, N., Dezawa, M. & Ide, C., Apr 2005, In : Experimental Neurology. 192, 2, p. 251-264 14 p.

Research output: Contribution to journalArticle

245 Scopus citations

Potential of bone marrow stromal cells in applications for neuro-degenerative, neuro-traumatic and muscle degenerative diseases

Dezawa, M., Ishikawa, H., Hoshino, M., Itokazu, Y. & Nabeshima, Y. I., Oct 2005, In : Current Neuropharmacology. 3, 4, p. 257-266 10 p.

Research output: Contribution to journalReview article

38 Scopus citations
2004

Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation

Dezawa, M., Kanno, H., Hoshino, M., Cho, H., Matsumoto, N., Itokazu, Y., Tajima, N., Yamada, H., Sawada, H., Ishikawa, H., Mimura, T., Kitada, M., Suzuki, Y. & Ide, C., Jun 2004, In : Journal of Clinical Investigation. 113, 12, p. 1701-1710 10 p.

Research output: Contribution to journalArticle

619 Scopus citations
2000

Atomic force microscopy with carbon nanotube probe resolves the subunit organization of protein complexes

Hohmura, K. I., Itokazu, Y., Yoshimura, S. H., Mizuguchi, G., Masamura, Y. S., Takeyasu, K., Shiomi, Y., Tsurimoto, T., Nishijima, H., Akita, S. & Nakayama, Y., 2000, In : Journal of Electron Microscopy. 49, 3, p. 415-21 7 p.

Research output: Contribution to journalArticle

36 Scopus citations