• 3275 Citations
  • 35 h-Index
20072020

Research output per year

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Research Output

2020

Expression of mRNAs, miRNAs, and lncRNAs in human trabecular meshwork cells upon mechanical stretch

Youngblood, H., Cai, J., Drewry, M. D., Helwa, I., Hu, E., Liu, S., Yu, H., Mu, H., Hu, Y., Perkumas, K., Aboobakar, I. F., Johnson, W. M., Stamer, W. D. & Liu, Y., May 1 2020, In : Investigative Ophthalmology and Visual Science. 61, 5, A21.

Research output: Contribution to journalArticle

Open Access

Freeze-Dried Extracellular Vesicles From Adipose-Derived Stem Cells Prevent Hypoxia-Induced Muscle Cell Injury

El Baradie, K. B. Y., Nouh, M., O’Brien, F., Liu, Y., Fulzele, S., Eroglu, A. & Hamrick, M. W., Mar 20 2020, In : Frontiers in Cell and Developmental Biology. 8, 181.

Research output: Contribution to journalArticle

Open Access
Open Access
2019

Association of a Primary Open-Angle Glaucoma Genetic Risk Score with Earlier Age at Diagnosis

Fan, B. J., Bailey, J. C., Igo, R. P., Kang, J. H., Boumenna, T., Brilliant, M. H., Budenz, D. L., Fingert, J. H., Gaasterland, T., Gaasterland, D., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S. E., Myers, J. S., Pericak-Vance, M. A., Realini, A., Rhee, D. J. & 13 others, Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Haines, J. L., Pasquale, L. R. & Wiggs, J. L., Oct 2019, In : JAMA Ophthalmology. 137, 10, p. 1190-1194 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Association of Genetic Variants with Primary Open-Angle Glaucoma among Individuals with African Ancestry

Hauser, M. A., Allingham, R. R., Aung, T., Van Der Heide, C. J., Taylor, K. D., Rotter, J. I., Wang, S. H. J., Bonnemaijer, P. W. M., Williams, S. E., Abdullahi, S. M., Abu-Amero, K. K., Anderson, M. G., Akafo, S., Alhassan, M. B., Asimadu, I., Ayyagari, R., Bakayoko, S., Nyamsi, P. B., Bowden, D. W., Bromley, W. C. & 73 others, Budenz, D. L., Carmichael, T. R., Challa, P., Chen, Y. D. I., Chuka-Okosa, C. M., Cooke Bailey, J. N., Costa, V. P., Cruz, D. A., Dubiner, H., Ervin, J. F., Feldman, R. M., Flamme-Wiese, M., Gaasterland, D. E., Garnai, S. J., Girkin, C. A., Guirou, N., Guo, X., Haines, J. L., Hammond, C. J., Herndon, L., Hoffmann, T. J., Hulette, C. M., Hydara, A., Igo, R. P., Jorgenson, E., Kabwe, J., Kilangalanga, N. J., Kizor-Akaraiwe, N., Kuchtey, R. W., Lamari, H., Li, Z., Liebmann, J. M., Liu, Y., Loos, R. J. F., Melo, M. B., Moroi, S. E., Msosa, J. M., Mullins, R. F., Nadkarni, G., Napo, A., Ng, M. C. Y., Nunes, H. F., Obeng-Nyarkoh, E., Okeke, A., Okeke, S., Olaniyi, O., Olawoye, O., Oliveira, M. B., Pasquale, L. R., Perez-Grossmann, R. A., Pericak-Vance, M. A., Qin, X., Ramsay, M., Resnikoff, S., Richards, J. E., Schimiti, R. B., Sim, K. S., Sponsel, W. E., Svidnicki, P. V., Thiadens, A. A. H. J., Uche, N. J., Van Duijn, C. M., De Vasconcellos, J. P. C., Wiggs, J. L., Zangwill, L. M., Risch, N., Milea, D., Ashaye, A., Klaver, C. C. W., Weinreb, R. N., Ashley Koch, A. E., Fingert, J. H. & Khor, C. C., Nov 5 2019, In : JAMA - Journal of the American Medical Association. 322, 17, p. 1682-1691 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss

Singleton, Q., Vaibhav, K., Braun, M., Patel, C., Khayrullin, A., Mendhe, B., Lee, B. R., Kolhe, R., Kaiser, H., Awad, M. E., Fariyike, T., Elsayed, R., Elsalanty, M., Isales, C. M., Liu, Y., Hamrick, M. W., Dhandapani, K. M. & Fulzele, S., Jan 17 2019, In : Fuel Cells. 8, 1

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles

Lee, B. R., Sanstrum, B. J., Liu, Y. & Kwon, S. H., Dec 1 2019, In : Scientific reports. 9, 1, 20049.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Erratum to: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (Nature Communications, (2018), 9, 1, (1864), 10.1038/s41467-018-03646-6)

Blue Mountains Eye Study - GWAS group, Wellcome Trust Case Control Consortium 2 (WTCCC2) & NEIGHBORHOOD Consortium, Dec 1 2019, In : Nature communications. 10, 1, 155.

Research output: Contribution to journalComment/debate

Open Access
8 Scopus citations

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium & UK Biobank Eye and Vision Consortium, Dec 1 2019, In : Communications Biology. 2, 1, 435.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells

Fulzele, S. T., Mendhe, B., Khayrullin, A., Johnson, M. H., Kaiser, H., Liu, Y., Isales, C. M. & Hamrick, M. W., Mar 31 2019, In : Aging. 11, 6, p. 1791-1803 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus

Khaled, M. L., Bykhovskaya, Y., Gu, C., Liu, A., Drewry, M. D., Chen, Z., Mysona, B. A., Parker, E., McNabb, R. P., Yu, H., Lu, X., Wang, J., Li, X., Al-Muammar, A., Rotter, J. I., Porter, L. F., Estes, A., Watsky, M. A., Smith, S. B., Xu, H. & 5 others, Abu-Amero, K. K., Kuo, A., Shears, S. B., Rabinowitz, Y. S. & Liu, Y., Dec 1 2019, In : Scientific reports. 9, 1, 19406.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Transcriptional profiling of corneal stromal cells derived from patients with keratoconus

Sharif, R., Khaled, M. L., McKay, T. B., Liu, Y. & Karamichos, D., Dec 1 2019, In : Scientific reports. 9, 1, 12567.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Update on the genetics of primary open-angle glaucoma

Youngblood, H., Hauser, M. A. & Liu, Y., Nov 2019, In : Experimental eye research. 188, 107795.

Research output: Contribution to journalReview article

5 Scopus citations
2018

Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma

Gharahkhani, P., Burdon, K. P., Cooke Bailey, J. N., Hewitt, A. W., Law, M. H., Pasquale, L. R., Kang, J. H., Haines, J. L., Souzeau, E., Zhou, T., Siggs, O. M., Landers, J., Awadalla, M., Sharma, S., Mills, R. A., Ridge, B., Lynn, D., Casson, R., Graham, S. L., Goldberg, I. & 45 others, White, A., Healey, P. R., Grigg, J., Lawlor, M., Mitchell, P., Ruddle, J., Coote, M., Walland, M., Best, S., Vincent, A., Gale, J., Radfordsmith, G., Whiteman, D. C., Montgomery, G. W., Martin, N. G., MacKey, D. A., Wiggs, J. L., MacGregor, S., Craig, J. E., Allingham, R. R., Brilliant, M., Budenz, D. L., Fingert, J. H., Gaasterland, D., Gaasterland, T., Hark, L., Hauser, M., Igo, R. P., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S., Pericak-Vance, M., Realini, A., Rhee, D., Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G. & Zack, D. J., Dec 1 2018, In : Scientific reports. 8, 1, 3124.

Research output: Contribution to journalArticle

8 Scopus citations

A Novel Cx50 Insert Mutation from a Chinese Congenital Cataract Family Impairs Its Cellular Membrane Localization and Function

Cui, X., Zhou, Z., Zhu, K., Feng, R., Han, J., Li, M., Wang, S., Li, J., Zhang, J., Jiang, Q., Zhang, W., Mu, H., Liu, Y. & Hu, Y., May 1 2018, In : DNA and cell biology. 37, 5, p. 449-456 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

Keller, K. E., Bhattacharya, S. K., Borrás, T., Brunner, T. M., Chansangpetch, S., Clark, A. F., Dismuke, W. M., Du, Y., Elliott, M. H., Ethier, C. R., Faralli, J. A., Freddo, T. F., Fuchshofer, R., Giovingo, M., Gong, H., Gonzalez, P., Huang, A., Johnstone, M. A., Kaufman, P. L., Kelley, M. J. & 37 others, Knepper, P. A., Kopczynski, C. C., Kuchtey, J. G., Kuchtey, R. W., Kuehn, M. H., Lieberman, R. L., Lin, S. C., Liton, P., Liu, Y., Lütjen-Drecoll, E., Mao, W., Masis-Solano, M., McDonnell, F., McDowell, C. M., Overby, D. R., Pattabiraman, P. P., Raghunathan, V. K., Rao, P. V., Rhee, D. J., Chowdhury, U. R., Russell, P., Samples, J. R., Schwartz, D., Stubbs, E. B., Tamm, E. R., Tan, J. C., Toris, C. B., Torrejon, K. Y., Vranka, J. A., Wirtz, M. K., Yorio, T., Zhang, J., Zode, G. S., Fautsch, M. P., Peters, D. M., Acott, T. S. & Stamer, W. D., Jun 2018, In : Experimental eye research. 171, p. 164-173 10 p.

Research output: Contribution to journalShort survey

41 Scopus citations

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Iglesias, A. I., Mishra, A., Vitart, V., Bykhovskaya, Y., Höhn, R., Springelkamp, H., Cuellar-Partida, G., Gharahkhani, P., Bailey, J. N. C., Willoughby, C. E., Li, X., Yazar, S., Nag, A., Khawaja, A. P., Polašek, O., Siscovick, D., Mitchell, P., Tham, Y. C., Haines, J. L., Kearns, L. S. & 124 others, Hayward, C., Shi, Y., Van Leeuwen, E. M., Taylor, K. D., Wang, J. J., Rochtchina, E., Attia, J., Scott, R., Holliday, E. G., Baird, P. N., Xie, J., Inouye, M., Viswanathan, A., Sim, X., Bonnemaijer, P., Rotter, J. I., Martin, N. G., Zeller, T., Mills, R. A., Staffieri, S. E., Jonas, J. B., Schmidtmann, I., Boutin, T., Kang, J. H., Lucas, S. E. M., Wong, T. Y., Beutel, M. E., Wilson, J. F., Allingham, R. R., Brilliant, M. H., Budenz, D. L., Christen, W. G., Fingert, J., Friedman, D. S., Gaasterland, D., Gaasterland, T., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Loomis, S. J., Moroi, S. E., Pericak-Vance, M. A., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Zhang, K., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Uitterlinden, A. G., Vithana, E. N., Foster, P. J., Hysi, P. G., Hewitt, A. W., Khor, C. C., Pasquale, L. R., Montgomery, G. W., Klaver, C. C. W., Aung, T., Pfeiffer, N., MacKey, D. A., Hammond, C. J., Cheng, C. Y., Craig, J. E., Rabinowitz, Y. S., Wiggs, J. L., Burdon, K. P., Van Duijn, C. M. & MacGregor, S., Dec 1 2018, In : Nature communications. 9, 1, 1864.

Research output: Contribution to journalArticle

13 Scopus citations

Differential expression of coding and long noncoding rnas in keratoconus-affected corneas

Khaled, M. L., Bykhovskaya, Y., Yablonski, S. E. R., Li, H., Drewry, M. D., Aboobakar, I. F., Estes, A. J., Gao, X. R., Stamer, W. D., Xu, H., Allingham, R. R., Hauser, M. A., Rabinowitz, Y. S. & Liu, Y., Jun 2018, In : Investigative Ophthalmology and Visual Science. 59, 7, p. 2717-2728 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma

Drewry, M. D., Challa, P., Kuchtey, J. G., Navarro, I., Helwa, I., Hu, Y., Mu, H., Stamer, W. D., Kuchtey, R. W. & Liu, Y., Apr 1 2018, In : Human Molecular Genetics. 27, 7, p. 1263-1275 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Emerging role of extracellular vesicles in musculoskeletal diseases

Murphy, C., Withrow, J., Hunter, M., Liu, Y., Tang, Y. L., Fulzele, S. & Hamrick, M. W., Apr 2018, In : Molecular Aspects of Medicine. 60, p. 123-128 6 p.

Research output: Contribution to journalReview article

19 Scopus citations

Epigenetic modifications in hyperhomocysteinemia; potential role in diabetic retinopathy and age-related macular degeneration

Elmasry, K., Mohamed, R., Sharma, I., Elsherbiny, N. M., Liu, Y., Al-Shabrawey, M. & Tawfik, A., Jan 1 2018, In : Oncotarget. 9, 16, p. 12562-12590 29 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exosome-Derived Dystrophin from Allograft Myogenic Progenitors Improves Cardiac Function in Duchenne Muscular Dystrophic Mice

Su, X., Jin, Y., Shen, Y., Ju, C., Cai, J., Liu, Y., Kim, I., Wang, Y., Yu, H., Weintraub, N. L., Jiang, M. & Tang, Y. L., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticle

7 Scopus citations

Exosomes from Suxiao Jiuxin pill-treated cardiac mesenchymal stem cells decrease H3K27 demethylase UTX expression in mouse cardiomyocytes in vitro

Ruan, X. F., Li, Y. J., Ju, C. W., Shen, Y., Lei, W., Chen, C., Li, Y., Yu, H., Liu, Y., Kim, I., Wang, X. L., Weintraub, N. L. & Tang, Y. L., Apr 1 2018, In : Acta Pharmacologica Sinica. 39, 4, p. 579-586 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Extracellular vesicle-mediated long-range communication in stressed retinal pigment epithelial cell monolayers

Shah, N., Ishii, M., Brandon, C., Ablonczy, Z., Cai, J., Liu, Y., Chou, C. J. & Rohrer, B., Aug 2018, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 8, p. 2610-2622 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Family-based genome-wide association study of south Indian pedigrees supports WNT7B as a central corneal thickness locus

Fan, B. J., Chen, X., Sondhi, N., Sharmila, P. F., Soumittra, N., Sripriya, S., Sacikala, S., Asokan, R., Friedman, D. S., Pasquale, L. R., Gao, X. R., Vijaya, L., Bailey, J. C., Vitart, V., Macgregor, S., Hammond, C. J., Khor, C. C., Haines, J. L., George, R., Wiggs, J. L. & 70 others, Allingham, R. R., Gao, X. R., Gauderman, J., Hauser, M., Rotter, J. I., Varma, R., Wiggs, J., Aung, T., Burdon, K. P., Cheng, C. Y., Craig, J. E., Cree, A. J., Gharahkhani, P., Hewitt, A. W., Höhn, R., Hysi, P., Iglesias Gonzalez, A. I., Jonas, J., Khawaja, A., Khor, C. C., Klaver, C. C. W., Pasutto, F., Macgregor, S., Mackey, D., Mitchell, P., Mishra, A., Pang, C., Pasquale, L. R., Pasutto, F., Springelkamp, H., Thorleifsson, G., Thorsteinsdottir, U., van Duijn, C. M., Viswanathan, A., Vitart, V., Wiggs, J. L., Wojciechowski, R., Wong, T., Young, T. L., Zeller, T., Allingham, R., Brilliant, M., Budenz, D., Bailey, J. C., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J. L., Hauser, M., Igo, R., Kang, J. H., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S., Pasquale, L. R., Realini, A., Rhee, D., Richards, J. R., Ritch, R., Schuman, J., Scott, W. K., Singh, K., Sit, A., Vollrath, D., Weinreb, R. N., Wiggs, J. L., Wollstein, G. & Zack, D., May 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2495-2502 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

International Glaucoma Genetics Consortium & NEIGHBORHOOD Consortium, Jan 1 2018, In : PLoS Genetics. 14, 1, e1007145.

Research output: Contribution to journalArticle

8 Scopus citations

Suxiao Jiuxin pill promotes exosome secretion from mouse cardiac mesenchymal stem cells in vitro

Ruan, X. F., Ju, C. W., Shen, Y., Liu, Y., Kim, I., Yu, H., Weintraub, N. L., Wang, X. L. & Tang, Y. L., Apr 1 2018, In : Acta Pharmacologica Sinica. 39, 4, p. 569-578 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Testosterone pathway genetic polymorphisms in relation to primary open-angle glaucoma: An analysis in two large datasets

Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium, Feb 2018, In : Investigative Ophthalmology and Visual Science. 59, 2, p. 629-636 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Transplantation of Cardiac Mesenchymal Stem Cell-Derived Exosomes for Angiogenesis

Ju, C., Li, Y., Shen, Y., Liu, Y., Cai, J., Liu, N., Ma, G. & Tang, Y., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticle

6 Scopus citations

Transplantation of Cardiac Mesenchymal Stem Cell-Derived Exosomes Promotes Repair in Ischemic Myocardium

Ju, C., Shen, Y., Ma, G., Liu, Y., Cai, J., Kim, I. M., Weintraub, N. L., Liu, N. & Tang, Y., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalArticle

17 Scopus citations
2017

A comparative study of serum exosome isolation using differential ultracentrifugation and three commercial reagents

Helwa, I., Cai, J., Drewry, M. D., Zimmerman, A., Dinkins, M. B., Khaled, M. L., Seremwe, M., Dismuke, W. M., Bieberich, E., Stamer, W. D., Hamrick, M. W. & Liu, Y., Jan 2017, In : PloS one. 12, 1, e0170628.

Research output: Contribution to journalArticle

169 Scopus citations

Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sample

Pasquale, L. R., Aschard, H., Kang, J. H., Bailey, J. N. C., Lindström, S., Chasman, D. I., Christen, W. G., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J., Budenz, D. L., Realini, T., Gaasterland, T., Gaasterland, D., Scott, W. K. & 21 others, Singh, K., Sit, A. J., Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Havens, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Haines, J. L. & Wiggs, J. L., Jan 1 2017, In : Menopause. 24, 2, p. 150-156 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Exosome production and its regulation of EGFR during wound healing in renal tubular cells

Zhou, X., Zhang, W., Yao, Q., Zhang, H., Dong, G., Zhang, M., Liu, Y., Chen, J. & Dong, Z., Jan 1 2017, In : American Journal of Physiology - Renal Physiology. 312, 6, p. F963-F970

Research output: Contribution to journalArticle

19 Scopus citations

Further evidence for a role of the ADRB2 gene in risk for posttraumatic stress disorder

Hauser, M. A., Garrett, M. E., Liu, Y., Dennis, M. F., Kimbrel, N. A., Veterans Affairs Mid-Atlantic Mental Illness Research, Education, A. M-A. M. I. R. E., Beckham, J. C. & Ashley-Koch, A. E., Jan 1 2017, In : Journal of Psychiatric Research. 84, p. 59-61 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

Kolhe, R. B., Hunter, D. M., Liu, S., Jadeja, R. N., Pundkar, C., Mondal, A. K., Mendhe, B., Drewry, M., Rojiani, M. V., Liu, Y., Isales, C. M., Guldberg, R. E., Hamrick, M. W. & Fulzele, S. T., Dec 1 2017, In : Scientific reports. 7, 1, 2029.

Research output: Contribution to journalArticle

56 Scopus citations

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

Aung, T., Ozaki, M., Lee, M. C., Schlötzer-Schrehardt, U., Thorleifsson, G., Mizoguchi, T., Igo, R. P., Haripriya, A., Williams, S. E., Astakhov, Y. S., Orr, A. C., Burdon, K. P., Nakano, S., Mori, K., Abu-Amero, K., Hauser, M., Li, Z., Prakadeeswari, G., Bailey, J. N. C., Cherecheanu, A. P. & 269 others, Kang, J. H., Nelson, S., Hayashi, K., Manabe, S. I., Kazama, S., Zarnowski, T., Inoue, K., Irkec, M., Coca-Prados, M., Sugiyama, K., Järvelä, I., Schlottmann, P., Lerner, S. F., Lamari, H., Nilgün, Y., Bikbov, M., Park, K. H., Cha, S. C., Yamashiro, K., Zenteno, J. C., Jonas, J. B., Kumar, R. S., Perera, S. A., Chan, A. S. Y., Kobakhidze, N., George, R., Vijaya, L., Do, T., Edward, D. P., De Juan Marcos, L., Pakravan, M., Moghimi, S., Ideta, R., Bach-Holm, D., Kappelgaard, P., Wirostko, B., Thomas, S., Gaston, D., Bedard, K., Greer, W. L., Yang, Z., Chen, X., Huang, L., Sang, J., Jia, H., Jia, L., Qiao, C., Zhang, H., Liu, X., Zhao, B., Wang, Y. X., Xu, L., Leruez, S., Reynier, P., Chichua, G., Tabagari, S., Uebe, S., Zenkel, M., Berner, D., Mossböck, G., Weisschuh, N., Hoja, U., Welge-Luessen, U. C., Mardin, C., Founti, P., Chatzikyriakidou, A., Pappas, T., Anastasopoulos, E., Lambropoulos, A., Ghosh, A., Shetty, R., Porporato, N., Saravanan, V., Venkatesh, R., Shivkumar, C., Kalpana, N., Sarangapani, S., Kanavi, M. R., Beni, A. N., Yazdani, S., Lashay, A., Naderifar, H., Khatibi, N., Fea, A., Lavia, C., Dallorto, L., Rolle, T., Frezzotti, P., Paoli, D., Salvi, E., Manunta, P., Mori, Y., Miyata, K., Higashide, T., Chihara, E., Ishiko, S., Yoshida, A., Yanagi, M., Kiuchi, Y., Ohashi, T., Sakurai, T., Sugimoto, T., Chuman, H., Aihara, M., Inatani, M., Miyake, M., Gotoh, N., Matsuda, F., Yoshimura, N., Ikeda, Y., Ueno, M., Sotozono, C., Jeoung, J. W., Sagong, M., Park, K. H., Ahn, J., Cruz-Aguilar, M., Ezzouhairi, S. M., Rafei, A., Chong, Y. F., Ng, X. Y., Goh, S. R., Chen, Y., Yong, V. H. K., Khan, M. I., Olawoye, O. O., Ashaye, A. O., Ugbede, I., Onakoya, A., Kizor-Akaraiwe, N., Teekhasaenee, C., Suwan, Y., Supakontanasan, W., Okeke, S., Uche, N. J., Asimadu, I., Ayub, H., Akhtar, F., Kosior-Jarecka, E., Lukasik, U., Lischinsky, I., Castro, V., Grossmann, R. P., Megevand, G. S., Roy, S., Dervan, E., Silke, E., Rao, A., Sahay, P., Fornero, P., Cuello, O., Sivori, D., Zompa, T., Mills, R. A., Souzeau, E., Mitchell, P., Wang, J. J., Hewitt, A. W., Coote, M., Crowston, J. G., Astakhov, S. Y., Akopov, E. L., Emelyanov, A., Vysochinskaya, V., Kazakbaeva, G., Fayzrakhmanov, R., Al-Obeidan, S. A., Owaidhah, O., Aljasim, L. A., Chowbay, B., Foo, J. N., Soh, R. Q., Sim, K. S., Xie, Z., Cheong, A. W. O., Mok, S. Q., Soo, H. M., Chen, X. Y., Peh, S. Q., Heng, K. K., Husain, R., Ho, S. L., Hillmer, A. M., Cheng, C. Y., Escudero-Domínguez, F. A., González-Sarmiento, R., Martinon-Torres, F., Salas, A., Pathanapitoon, K., Hansapinyo, L., Wanichwecharugruang, B., Kitnarong, N., Sakuntabhai, A., Nguyn, H. X., Nguyn, G. T. T., Nguyn, T. V., Zenz, W., Binder, A., Klobassa, D. S., Hibberd, M. L., Davila, S., Herms, S., Nöthen, M. M., Moebus, S., Rautenbach, R. M., Ziskind, A., Carmichael, T. R., Ramsay, M., Álvarez, L., García, M., González-Iglesias, H., Rodríguez-Calvo, P. P., Cueto, L. F. V., Oguz, Ç., Tamcelik, N., Atalay, E., Batu, B., Aktas, D., Kaslm, B., Wilson, M. R., Coleman, A. L., Liu, Y., Challa, P., Herndon, L., Kuchtey, R. W., Kuchtey, J., Curtin, K., Chaya, C. J., Crandall, A., Zangwill, L. M., Wong, T. Y., Nakano, M., Kinoshita, S., Den Hollander, A. I., Vesti, E., Fingert, J. H., Lee, R. K., Sit, A. J., Shingleton, B. J., Wang, N., Cusi, D., Qamar, R., Kraft, P., Pericak-Vance, M. A., Raychaudhuri, S., Heegaard, S., Kivelä, T., Reis, A., Kruse, F. E., Weinreb, R. N., Pasquale, L. R., Haines, J. L., Thorsteinsdottir, U., Jonasson, F., Allingham, R. R., Milea, D., Ritch, R., Kubota, T., Tashiro, K., Vithana, E. N., Micheal, S., Topouzis, F., Craig, J. E., Dubina, M., Sundaresan, P., Stefansson, K., Wiggs, J. L., Pasutto, F. & Khor, C. C., Jul 1 2017, In : Nature Genetics. 49, 7, p. 993-1004 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Genetic correlations between intraocular pressure, blood pressure and primary open-angle glaucoma: A multi-cohort analysis

Aschard, H., Kang, J. H., Iglesias, A. I., Hysi, P., Cooke Bailey, J. N., Khawaja, A. P., Allingham, R. R., Ashley-Koch, A., Lee, R. K., Moroi, S. E., Brilliant, M. H., Wollstein, G., Schuman, J. S., Fingert, J. H., Budenz, D. L., Realini, T., Gaasterland, T., Scott, W. K., Singh, K., Sit, A. J. & 25 others, Igo, R. P., Song, Y. E., Hark, L., Ritch, R., Rhee, D. J., Gulati, V., Haven, S., Vollrath, D., Zack, D. J., Medeiros, F., Weinreb, R. N., Cheng, C. Y., Chasman, D. I., Christen, W. G., Pericak-Vance, M. A., Liu, Y., Kraft, P., Richards, J. E., Rosner, B. A., Hauser, M. A., Klaver, C. C. W., Vanduijn, C. M., Haines, J., Wiggs, J. L. & Pasquale, L. R., Nov 1 2017, In : European Journal of Human Genetics. 25, 11, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

HIF-1-mediated production of exosomes during hypoxia is protective in renal tubular cells

Zhang, W., Zhou, X., Yao, Q., Liu, Y., Zhang, H. & Dong, Z., Oct 2017, In : American Journal of Physiology - Renal Physiology. 313, 4, p. F906-F913

Research output: Contribution to journalArticle

30 Scopus citations

Isolation of Extracellular Vesicles from Stem Cells

Chen, Z., Li, Y., Yu, H., Shen, Y., Ju, C., Ma, G., Liu, Y., Kim, I., Weintraub, N. L. & Tang, Y. L., Jan 1 2017, In : Methods in molecular biology (Clifton, N.J.). 1660, p. 389-394 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Major review: Molecular genetics of primary open-angle glaucoma

Liu, Y. & Allingham, R. R., Jul 2017, In : Experimental eye research. 160, p. 62-84 23 p.

Research output: Contribution to journalReview article

40 Scopus citations
46 Scopus citations

Molecular and Histopathological Changes Associated with Keratoconus

Khaled, M. L., Helwa, I., Drewry, M., Seremwe, M., Estes, A. & Liu, Y., Jan 1 2017, In : BioMed Research International. 2017, 7803029.

Research output: Contribution to journalReview article

25 Scopus citations

TSC1 mutations in Keratoconus Patients with or without tuberous sclerosis

Bykhovskaya, Y., Fardaei, M., Khaled, M. L., Nejabat, M., Salouti, R., Dastsooz, H., Liu, Y., Inaloo, S. & Rabinowitz, Y. S., Dec 2017, In : Investigative Ophthalmology and Visual Science. 58, 14, p. 6462-6469 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

A common variant in MIR182 is associated with primary open-angle glaucoma in the NEIGHBORHOOD consortium

Liu, Y., Bailey, J. C., Helwa, I., Dismuke, W. M., Cai, J., Drewry, M., Brilliant, M. H., Budenz, D. L., Christen, W. G., Chasman, D. I., Fingert, J. H., Gaasterland, D., Gaasterland, T., Gordon, M. O., Igo, R. P., Kang, J. H., Kass, M. A., Kraft, P., Lee, R. K., Lichter, P. & 25 others, Moroi, S. E., Realini, A., Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Song, Y. E., Vollrath, D., Weinreb, R., Medeiros, F., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M. A., Gonzalez, P., Stamer, W. D., Kuchtey, J., Kuchtey, R. W., Allingham, R. R., Hauser, M. A., Pasquale, L. R., Haines, J. L. & Wiggs, J. L., Aug 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 10, p. 4528-4535 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Assessing the association of mitochondrial genetic variation with primary open-angle glaucoma using gene-set analyses

Khawaja, A. P., Cooke Bailey, J. N., Kang, J. H., Rand Allingham, R., Hauser, M. A., Brilliant, M., Budenz, D. L., Christen, W. G., Fingert, J., Gaasterland, D., Gaasterland, T., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Medeiros, F., Moroi, S. E., Richards, J. E., Realini, T., Ritch, R. & 13 others, Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G., Zack, D. J., Zhang, K., Pericak-Vance, M., Weinreb, R. N., Haines, J. L., Pasquale, L. R. & Wiggs, J. L., Sep 2016, In : Investigative Ophthalmology and Visual Science. 57, 11, p. 5046-5052 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

eMERGE Network & NEIGHBOR Consortium, Sep 2016, In : PLoS Genetics. 12, 9, e1006186.

Research output: Contribution to journalArticle

17 Scopus citations

Extracellular vesicles in diagnosis and therapy of kidney diseases

Zhang, W., Zhou, X., Zhang, H., Yao, Q., Liu, Y. & Dong, Z., Jan 1 2016, In : American Journal of Physiology - Renal Physiology. 311, 5, p. F844-F851

Research output: Contribution to journalReview article

44 Scopus citations

Extracellular vesicles in the pathogenesis of rheumatoid arthritis and osteoarthritis

Withrow, J., Murphy, C., Liu, Y., Hunter, M., Fulzele, S. & Hamrick, M. W., Dec 1 2016, In : Arthritis Research and Therapy. 18, 1, 286.

Research output: Contribution to journalReview article

73 Scopus citations