• 19809 Citations
  • 67 h-Index
1992 …2020

Research output per year

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Research Output

Non-coding RNAs in kidney injury and repair

Liu, Z., Wang, Y., Shu, S., Cai, J., Tang, C. & Dong, Z., Aug 2019, In : American Journal of Physiology - Cell Physiology. 317, 2, p. C177-C188

Research output: Contribution to journalArticle

8 Scopus citations

Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation

Livingston, M. J., Pabla, N., Murphy, R. F., Yang, T., Yin, X. M., Degenhardt, K., White, E. & Dong, Z., Jan 26 2007, In : Journal of Biological Chemistry. 282, 4, p. 2636-2645 10 p.

Research output: Contribution to journalArticle

80 Scopus citations

Ocular cytomegalovirus latency exacerbates the development of choroidal neovascularization

Xu, J., Liu, X., Zhang, X., Marshall, B., Dong, Z., Liu, Y., Espinosa-Heidmann, D. G. & Zhang, M., Jun 1 2020, In : Journal of Pathology. 251, 2, p. 200-212 13 p.

Research output: Contribution to journalArticle

OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury

Xiao, X., Hu, Y., Quirós, P. M., Wei, Q., López-Otín, C. & Dong, Z., Jun 1 2014, In : American Journal of Physiology - Renal Physiology. 306, 11, p. F1318-F1326

Research output: Contribution to journalArticle

51 Scopus citations

P53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease

Ma, Z., Li, L., Livingston, M. J., Zhang, D., Mi, Q., Zhang, M., Ding, H. F., Huo, Y., Mei, C. & Dong, Z., Sep 1 2020, In : Journal of Clinical Investigation. 130, 9, p. 5011-5026 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

P53-cyclophilin D mediates renal tubular cell apoptosis in ischemia-reperfusion-induced acute kidney injury

Yang, H., Li, R., Zhang, L., Zhang, S., Dong, W., Chen, Y., Wang, W., Li, C., Ye, Z., Zhao, X., Li, Z., Wu, Y., Zhang, M., Liu, S., Dong, Z. & Liang, X., Nov 2019, In : American Journal of Physiology - Renal Physiology. 317, 5, p. F1311-F1317

Research output: Contribution to journalArticle

5 Scopus citations

P53 induces miR199a-3p to suppress SOCS7 for STAT3 activation and renal fibrosis in UUO

Yang, R., Xu, X., Li, H., Chen, J., Xiang, X., Dong, Z. & Zhang, D., Feb 27 2017, In : Scientific reports. 7, 43409.

Research output: Contribution to journalArticle

27 Scopus citations

P53 in kidney injury and repair: Mechanism and therapeutic potentials

Tang, C., Ma, Z., Zhu, J., Liu, Z., Liu, Y., Liu, Y., Cai, J. & Dong, Z., Mar 2019, In : Pharmacology and Therapeutics. 195, p. 5-12 8 p.

Research output: Contribution to journalReview article

14 Scopus citations

Paclitaxel: New uses for an old drug

Zhang, D., Yang, R., Wang, S. & Dong, Z., Feb 20 2014, In : Drug Design, Development and Therapy. 8, p. 279-284 6 p.

Research output: Contribution to journalArticle

67 Scopus citations
40 Scopus citations

Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling

Zhang, L., Xu, X., Yang, R., Chen, J., Wang, S., Yang, J., Xiang, X., He, Z., Zhao, Y., Dong, Z. & Zhang, D., Mar 15 2015, In : Drug Design, Development and Therapy. 9, p. 2139-2148 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction

Livingston, M. J., Ding, H. F., Huang, S., Hill, J. A., Yin, X. M. & Dong, Z., Jun 2 2016, In : Autophagy. 12, 6, p. 976-998 23 p.

Research output: Contribution to journalArticle

76 Scopus citations

PFKFB3 in smooth muscle promotes vascular remodeling in pulmonary arterial hypertension

Kovacs, L., Cao, Y., Han, W., Meadows, L., Kovacs-Kasa, A., Kondrikov, D., Verin, A. D., Barman, S. A., Dong, Z., Huo, Y. & Su, Y., Sep 1 2019, In : American journal of respiratory and critical care medicine. 200, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Phosphorylation of ribosomal protein S6 mediates compensatory renal hypertrophy

Xu, J., Chen, J., Dong, Z., Meyuhas, O. & Chen, J., Mar 1 2015, In : Kidney International. 87, 3, p. 543-556 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury

Wang, Y., Tang, C., Cai, J., Chen, G., Zhang, D., Zhang, Z. & Dong, Z., Nov 1 2018, In : Cell Death and Disease. 9, 11, 1113.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury

Tang, C., Han, H., Yan, M., Zhu, S., Liu, J., Liu, Z., He, L., Tan, J., Liu, Y., Liu, H., Sun, L., Duan, S., Peng, Y., Liu, F., Yin, X. M., Zhang, Z. & Dong, Z., May 4 2018, In : Autophagy. 14, 5, p. 880-897 18 p.

Research output: Contribution to journalArticle

58 Scopus citations

PKCδ-mediated Nox2 activation promotes fluid-phase pinocytosis of antigens by immature dendritic cells

Singla, B., Ghoshal, P., Lin, H., Wei, Q., Dong, Z. & Csányi, G., Mar 26 2018, In : Frontiers in immunology. 9, MAR, 537.

Research output: Contribution to journalArticle

7 Scopus citations

PKC-δ promotes renal tubular cell apoptosis associated with proteinuria

Li, X., Pabla, N., Wei, Q., Dong, G., Messing, R. O., Wang, C. Y. & Dong, Z., Jul 2010, In : Journal of the American Society of Nephrology. 21, 7, p. 1115-1124 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Postmitochondrial regulation of apoptosis by bicarbonate

Dong, Z., Wang, J. & Zhong, Q., Aug 15 2003, In : Experimental Cell Research. 288, 2, p. 301-312 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Preface to first edition

Yin, X. M. & Dong, Z., Jan 1 2009, Essentials of Apoptosis: A Guide for Basic and Clinical Research. Humana Press Inc., p. vii-viii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

1 Scopus citations

Preface to second edition

Yin, X. M. & Dong, Z., Jan 1 2009, Essentials of Apoptosis: A Guide for Basic and Clinical Research. Humana Press Inc., p. v-vi

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Primary cilia and kidney injury: Current research status and future perspectives

Wang, S. & Dong, Z., Oct 15 2013, In : American Journal of Physiology - Renal Physiology. 305, 8, p. F1085-F1098

Research output: Contribution to journalReview article

23 Scopus citations

PRKCD/PKCδ contributes to nephrotoxicity during cisplatin chemotherapy by suppressing autophagy

Zhang, D., Xu, X. & Dong, Z., Mar 4 2017, In : Autophagy. 13, 3, p. 631-632 2 p.

Research output: Contribution to journalComment/debate

14 Scopus citations

Prostaglandin D2 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in MDCK cells

Zhang, A., Dong, Z. & Yang, T., 2006, In : American Journal of Physiology - Renal Physiology. 291, 6, p. F1332-F1342

Research output: Contribution to journalArticle

44 Scopus citations
57 Scopus citations

Protection of ATP-depleted cells by impermeant strychnine derivatives: Implications for glycine cytoprotection

Dong, Z., Venkatachalam, M. A., Weinberg, J. M., Saikumar, P. & Patel, Y., 2001, In : American Journal of Pathology. 158, 3, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
1 Scopus citations

Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity

Sun, L., Liu, J., Yuan, Y., Zhang, I. & Dong, Z., Sep 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F469-F478

Research output: Contribution to journalArticle

5 Scopus citations

Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration

Su, S., Li, Y., Luo, Y., Sheng, Y., Su, Y., Padia, R. N., Pan, Z. K., Dong, Z. & Huang, S., Aug 27 2009, In : Oncogene. 28, 34, p. 3047-3057 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Protein kinase Cd suppresses autophagy to induce kidney cell apoptosis in cisplatin nephrotoxicity

Zhang, D., Pan, J., Xiang, X., Liu, Y., Dong, G., Livingston, M. J., Chen, J., Yin, X. M. & Dong, Z., Apr 2017, In : Journal of the American Society of Nephrology. 28, 4, p. 1131-1144 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

Protein kinase Cα-CARMA3 signaling axis links Ras to NF-κB for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells

Mahanivong, C., Chen, H. M., Yee, S. W., Pan, Z. K., Dong, Z. & Huang, S., Feb 21 2008, In : Oncogene. 27, 9, p. 1273-1280 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Protein kinase C-δ mediates kidney tubular injury in cold storage-associated kidney transplantation

Zhu, J., Zhang, G., Song, Z., Xiang, X., Shu, S., Liu, Z., Yang, D., Wei, Q. & Dong, Z., May 2020, In : Journal of the American Society of Nephrology. 31, 5, p. 1050-1065 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress

Guo, D., Han, J., Adam, B. L., Colburn, N. H., Wang, M-H., Dong, Z., Eizirik, D. L., She, J-X. & Wang, C. Y., Dec 2 2005, In : Biochemical and Biophysical Research Communications. 337, 4, p. 1308-1318 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

Rapamycin Enhances Repressed Autophagy and Attenuates Aggressive Progression in a Rat Model of IgA Nephropathy

Liu, D., Liu, Y., Chen, G., He, L., Tang, C., Wang, C., Yang, D., Li, H., Dong, Z. & Liu, H., Apr 1 2017, In : American Journal of Nephrology. 45, 4, p. 293-300 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Ratio of miR-196s to HOXC8 messenger RNA correlates with breast cancer cell migration and metastasis

Li, Y., Zhang, M., Chen, H., Dong, Z., Ganapathy, V., Thangaraju, M. & Huang, S., Oct 15 2010, In : Cancer Research. 70, 20, p. 7894-7904 11 p.

Research output: Contribution to journalArticle

117 Scopus citations

Reactive oxygen species-dependent RhoA activation mediates collagen synthesis in hyperoxic lung fibrosis

Kondrikov, D., Caldwell, R. B., Dong, Z. & Su, Y., Jun 1 2011, In : Free Radical Biology and Medicine. 50, 11, p. 1689-1698 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways

Wang, S., Livingston, M. J., Su, Y. & Dong, Z., 2015, In : Autophagy. 11, 4, p. 607-616 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Regulated cell death in AKI

Linkermann, A., Chen, G., Dong, G., Kunzendorf, U., Krautwald, S. & Dong, Z., Dec 1 2014, In : Journal of the American Society of Nephrology. 25, 12, p. 2689-2701 13 p.

Research output: Contribution to journalShort survey

198 Scopus citations

Regulation and pathological role of bid in ischemic acute kidney injury

Wei, Q. & Dong, Z., Nov 1 2007, In : Renal Failure. 29, 8, p. 935-940 6 p.

Research output: Contribution to journalReview article

4 Scopus citations

Regulation and pathological role of p53 in cisplatin nephrotoxicity

Jiang, M. & Dong, Z., Nov 2008, In : Journal of Pharmacology and Experimental Therapeutics. 327, 2, p. 300-307 8 p.

Research output: Contribution to journalReview article

99 Scopus citations

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation

Xu, Y., Wang, Y., Yan, S., Yang, Q., Zhou, Y., Zeng, X., Liu, Z., An, X., Flores Toque, H. A., Dong, Z., Jiang, X., Fulton, D. J., Weintraub, N. L., Li, Q., Bagi, Z., Hong, M., Boison, D., Wu, C. & Huo, Y., Dec 1 2017, In : Nature communications. 8, 1, 943.

Research output: Contribution to journalArticle

22 Scopus citations

Regulation of Hsf4b nuclear translocation and transcription activity by phosphorylation at threonine 472

Zhang, J., Ma, Z., Wang, J., Li, S., Zhang, Y., Wang, Y., Wang, M., Feng, X., Liu, X., Liu, G., Lou, Q., Cui, X., Ma, Y., Dong, Z. & Hu, Y. Z., Mar 1 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 3, p. 580-589 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

Brooks, C., Wei, Q., Cho, S. G. & Dong, Z., May 1 2009, In : Journal of Clinical Investigation. 119, 5, p. 1275-1285 11 p.

Research output: Contribution to journalArticle

444 Scopus citations

Regulation of mitochondrial morphological dynamics during apoptosis by Bcl-2 family proteins: A key in Bak?

Brooks, C. & Dong, Z., Dec 15 2007, In : Cell Cycle. 6, 24, p. 3043-3047 5 p.

Research output: Contribution to journalReview article

81 Scopus citations

Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: Entosis without matrix detachment

Wan, Q., Liu, J., Zheng, Z., Zhu, H., Chu, X., Dong, Z., Huang, S. & Du, Q., Jun 1 2012, In : Molecular Biology of the Cell. 23, 11, p. 2076-2091 16 p.

Research output: Contribution to journalArticle

34 Scopus citations

Regulation of PUMA-α by p53 in cisplatin-induced renal cell apoptosis

Livingston, M. J., Wei, Q., Wang, J., Du, Q., Yu, J., Zhang, L. & Dong, Z., Jul 6 2006, In : Oncogene. 25, 29, p. 4056-4066 11 p.

Research output: Contribution to journalArticle

155 Scopus citations

Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex

Liang, N., Zhang, C., Dill, P., Panasyuk, G., Pion, D., Koka, V., Gallazzini, M., Olson, E. N., Lam, H., Henske, E. P., Dong, Z., Apte, U., Pallet, N., Johnson, R. L., Terzi, F., Kwiatkowski, D. J., Scoazec, J. Y., Martignoni, G. & Pende, M., 2014, In : Journal of Experimental Medicine. 211, 11, p. 2249-2263 15 p.

Research output: Contribution to journalArticle

95 Scopus citations

Renal epoxyeicosatrienoic acid synthesis during pregnancy

Zhou, Y., Chang, H. H., Du, J., Wang, C. Y., Dong, Z. & Wang, M. H., Jan 2005, In : American Journal of Physiology - Renal Physiology. 288, 1 57-1, p. F221-F226

Research output: Contribution to journalArticle

15 Scopus citations

Renoprotective approaches and strategies in acute kidney injury

Yang, Y., Song, M., Liu, Y., Liu, H., Sun, L., Peng, Y., Liu, F., Venkatachalam, M. A. & Dong, Z., Jul 1 2016, In : Pharmacology and Therapeutics. 163, p. 58-73 16 p.

Research output: Contribution to journalReview article

53 Scopus citations
1 Scopus citations