• 19120 Citations
  • 65 h-Index
1992 …2020

Research output per year

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Research Output

2009

Apoptosis in acute kidney injury

Pabla, N., Wei, Q. & Dong, Z., Jan 1 2009, Essentials of Apoptosis: A Guide for Basic and Clinical Research. Humana Press Inc., p. 565-579 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Autophagy: Molecular machinery, regulation, and implications for renal pathophysiology

Periyasamy-Thandavan, S., Jiang, M., Schoenlein, P. & Dong, Z., Aug 1 2009, In : American Journal of Physiology - Renal Physiology. 297, 2, p. F244-F256

Research output: Contribution to journalReview article

113 Scopus citations

Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway

Jiang, M., Wang, C. Y., Huang, S., Yang, T. & Dong, Z., May 1 2009, In : American Journal of Physiology - Renal Physiology. 296, 5, p. F983-F993

Research output: Contribution to journalArticle

71 Scopus citations

Essentials of apoptosis: A guide for basic and clinical research

Yin, X. M. & Dong, Z., Jan 1 2009, Humana Press Inc. 728 p.

Research output: Book/ReportBook

11 Scopus citations

Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression

Chen, H., Zhu, G., Li, Y., Padia, R. N., Dong, Z., Pan, Z. K., Liu, K. & Huang, S., Dec 15 2009, In : Cancer Research. 69, 24, p. 9228-9235 8 p.

Research output: Contribution to journalArticle

129 Scopus citations

IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression

Yang, D., Wang, S., Brooks, C., Dong, Z., Schoenlein, P. V., Kumar, V., Ouyang, X., Xiong, H., Lahat, G., Hayes-Jordan, A., Lazar, A., Pollock, R., Lev, D. & Liu, K., Feb 1 2009, In : Cancer Research. 69, 3, p. 1080-1088 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

mPGES-1 deletion impairs diuretic response to acute water loading

Soodvilai, S., Jia, Z., Wang, M. H., Dong, Z. & Yang, T., May 1 2009, In : American Journal of Physiology - Renal Physiology. 296, 5, p. F1129-F1135

Research output: Contribution to journalArticle

30 Scopus citations

Preface to first edition

Yin, X. M. & Dong, Z., Jan 1 2009, Essentials of Apoptosis: A Guide for Basic and Clinical Research. Humana Press Inc., p. vii-viii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

1 Scopus citations

Preface to second edition

Yin, X. M. & Dong, Z., Jan 1 2009, Essentials of Apoptosis: A Guide for Basic and Clinical Research. Humana Press Inc., p. v-vi

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration

Su, S., Li, Y., Luo, Y., Sheng, Y., Su, Y., Padia, R. N., Pan, Z. K., Dong, Z. & Huang, S., Aug 27 2009, In : Oncogene. 28, 34, p. 3047-3057 11 p.

Research output: Contribution to journalArticle

66 Scopus citations

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

Brooks, C., Wei, Q., Cho, S. G. & Dong, Z., May 1 2009, In : Journal of Clinical Investigation. 119, 5, p. 1275-1285 11 p.

Research output: Contribution to journalArticle

430 Scopus citations
1 Scopus citations

Role of Aggregatibacter actinomycetemcomitans in glutathione catabolism

Chu, L., Xu, X., Su, J., Song, L., Lai, Y., Dong, Z. & Cappelli, D., Jun 1 2009, In : Oral Microbiology and Immunology. 24, 3, p. 236-242 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
140 Scopus citations

Tie2cre-induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development

Zhou, L., Seo, K. H., He, H. Z., Pacholczyk, R. W., Meng, D. M., Li, C. G., Xu, J., She, J-X., Dong, Z. & Mi, Q. S., Jun 23 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 25, p. 10266-10271 6 p.

Research output: Contribution to journalArticle

76 Scopus citations
2008

A stress-dependent SUMO4 sumoylation of its substrate proteins

Wei, W., Yang, P., Pang, J., Zhang, S., Wang, Y., Wang, M-H., Dong, Z., She, J-X. & Wang, C. Y., Oct 24 2008, In : Biochemical and Biophysical Research Communications. 375, 3, p. 454-459 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis

Pabla, N., Huang, S., Mi, Q. S., Daniel, R. & Dong, Z., Mar 7 2008, In : Journal of Biological Chemistry. 283, 10, p. 6572-6583 12 p.

Research output: Contribution to journalArticle

193 Scopus citations

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis (Journal of Biological Chemistry (2008) 283, (6572-6583))

Pabla, N., Huang, S., Mi, Q. S., Daniel, R. & Dong, Z., May 30 2008, In : Journal of Biological Chemistry. 283, 22, 1 p.

Research output: Contribution to journalComment/debate

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

Periyasamy-Thandavan, S., Jiang, M., Wei, Q., Smith, R., Yin, X. M. & Dong, Z., Sep 1 2008, In : Kidney International. 74, 5, p. 631-640 10 p.

Research output: Contribution to journalArticle

219 Scopus citations

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

Pabla, N. & Dong, Z., May 2008, In : Kidney International. 73, 9, p. 994-1007 14 p.

Research output: Contribution to journalReview article

990 Scopus citations

Colfibrate attenuates blood pressure and sodium retention in DOCA-salt hypertension

Zhou, Y., Luo, P., Chang, H. H., Huang, H., Yang, T., Dong, Z., Wang, C. Y. & Wang, M. H., Oct 1 2008, In : Kidney International. 74, 8, p. 1040-1048 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Effects of targeted Bcl-2 expression in mitochondria or endoplasmic reticulum on renal tubular cell apoptosis

Bhatt, K., Feng, L., Pabla, N., Liu, K., Smith, S. & Dong, Z., Mar 1 2008, In : American Journal of Physiology - Renal Physiology. 294, 3, p. F499-F507

Research output: Contribution to journalArticle

37 Scopus citations

Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice

Han, J., Zhong, J., Wei, W., Wang, Y., Huang, Y., Yang, P., Purohit, S. B., Dong, Z., Wang, M-H., She, J-X., Gong, F., Stern, D. M. & Wang, C. Y., Aug 1 2008, In : Diabetes. 57, 8, p. 2118-2127 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Induction of apoptosis in renal tubular cells by histone deacetylase inhibitors, a family of anticancer agents

Dong, G., Wang, L., Wang, C. Y., Yang, T., Kumar, M. V. & Dong, Z., Jun 1 2008, In : Journal of Pharmacology and Experimental Therapeutics. 325, 3, p. 978-984 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Microsomal prostaglandin synthase-1-derived prostaglandin E2 protects against angiotensin II-induced hypertension via inhibition of oxidative stress

Jia, Z., Guo, X., Zhang, H., Wang, M-H., Dong, Z. & Yang, T., Nov 1 2008, In : Hypertension. 52, 5, p. 952-959 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Nitro-oleic acid protects the mouse kidney from ischemia and reperfusion injury

Liu, H., Jia, Z., Soodvilai, S., Guan, G., Wang, M. H., Dong, Z., Symons, J. D. & Yang, T., Oct 2008, In : American Journal of Physiology - Renal Physiology. 295, 4, p. F942-F949

Research output: Contribution to journalArticle

55 Scopus citations

Protein kinase Cα-CARMA3 signaling axis links Ras to NF-κB for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells

Mahanivong, C., Chen, H. M., Yee, S. W., Pan, Z. K., Dong, Z. & Huang, S., Feb 21 2008, In : Oncogene. 27, 9, p. 1273-1280 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Regulation and pathological role of p53 in cisplatin nephrotoxicity

Livingston, M. J. & Dong, Z., Nov 1 2008, In : Journal of Pharmacology and Experimental Therapeutics. 327, 2, p. 300-307 8 p.

Research output: Contribution to journalReview article

98 Scopus citations
2007

Activation and involvement of p53 in cisplatin-induced nephrotoxicity

Wei, Q., Dong, G., Yang, T., Megyesi, J., Price, P. M. & Dong, Z., Oct 2007, In : American Journal of Physiology - Renal Physiology. 293, 4, p. F1282-F1291

Research output: Contribution to journalArticle

156 Scopus citations

Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins

Brooks, C., Wei, Q., Feng, L., Dong, G., Tao, Y., Mei, L., Xie, Z. J. & Dong, Z., Jul 10 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 28, p. 11649-11654 6 p.

Research output: Contribution to journalArticle

244 Scopus citations

Characterization of cell clones isolated from hypoxia-selected renal proximal tubular cells

Brooks, C., Wang, J., Yang, T. & Dong, Z., Jan 1 2007, In : American Journal of Physiology - Renal Physiology. 292, 1, p. F243-F252

Research output: Contribution to journalArticle

8 Scopus citations

Developmental regulation of calcineurin isoforms in the rodent kidney: Association with COX-2

Liu, H., Ye, W., Guan, G., Dong, Z., Jia, Z. & Yang, T., Dec 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 6, p. F1898-F1904

Research output: Contribution to journalArticle

7 Scopus citations

Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity

Jiang, M., Wei, Q., Pabla, N., Dong, G., Wang, C. Y., Yang, T., Smith, S. B. & Dong, Z., May 1 2007, In : Biochemical Pharmacology. 73, 9, p. 1499-1510 12 p.

Research output: Contribution to journalArticle

124 Scopus citations

IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression

Yang, D., Thangaraju, M., Browning, D. D., Dong, Z., Korchin, B., Lev, D. C., Ganapathy, V. & Liu, K., Oct 1 2007, In : Journal of Immunology. 179, 7, p. 4775-4782 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation

Livingston, M. J., Pabla, N., Murphy, R. F., Yang, T., Yin, X. M., Degenhardt, K., White, E. & Dong, Z., Jan 26 2007, In : Journal of Biological Chemistry. 282, 4, p. 2636-2645 10 p.

Research output: Contribution to journalArticle

78 Scopus citations

Regulation and pathological role of bid in ischemic acute kidney injury

Wei, Q. & Dong, Z., Nov 1 2007, In : Renal Failure. 29, 8, p. 935-940 6 p.

Research output: Contribution to journalReview article

4 Scopus citations

Regulation of mitochondrial morphological dynamics during apoptosis by Bcl-2 family proteins: A key in Bak?

Brooks, C. & Dong, Z., Dec 15 2007, In : Cell Cycle. 6, 24, p. 3043-3047 5 p.

Research output: Contribution to journalReview article

81 Scopus citations

The pathological role of Bax in cisplatin nephrotoxicity

Wei, Q., Dong, G., Franklin, J. & Dong, Z., Jul 1 2007, In : Kidney International. 72, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

158 Scopus citations

Tumor necrosis factor-α in cisplatin nephrotoxicity: A homebred foe?

Dong, Z. & Atherton, S. S., Jul 2007, In : Kidney International. 72, 1, p. 5-7 3 p.

Research output: Contribution to journalComment/debate

40 Scopus citations

Unique homologous siRNA blocks hypoxia-induced VEGF upregulation in human corneal cells and inhibits and regresses murine corneal neovascularization

Singh, N., Higgins, E., Amin, S., Jani, P., Richter, E., Patel, A., Kaur, R., Wang, J., Ambati, J., Dong, Z. & Ambati, B. K., Jan 1 2007, In : Cornea. 26, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

37 Scopus citations
2006
50 Scopus citations

Calcium in cell injury and death

Dong, Z., Saikumar, P., Weinberg, J. M. & Venkatachalam, M. A., Apr 19 2006, In : Annual Review of Pathology. 1, p. 405-434 30 p.

Research output: Contribution to journalReview article

163 Scopus citations

Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: Inactivation of its kinase activity toward p53

Wang, J., Pabla, N., Wang, C. Y., Wang, W., Schoenlein, P. V. & Dong, Z., Dec 14 2006, In : American Journal of Physiology - Renal Physiology. 291, 6, p. F1300-F1307

Research output: Contribution to journalArticle

38 Scopus citations

Characterization of cell clones stably transfected with short form caspase-9: Apoptotic resistance and Bcl-XL expression

Yi, X., Wang, J., Seol, D. W. & Dong, Z., Jan 1 2006, In : Molecular and Cellular Biochemistry. 282, 1-2, p. 1-12 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
52 Scopus citations

Deletion of microsomal prostaglandin E synthase-1 increases sensitivity to salt loading and angiotensin II infusion

Jia, Z., Zhang, A., Zhang, H., Dong, Z. & Yang, T., Nov 1 2006, In : Circulation research. 99, 11, p. 1243-1251 9 p.

Research output: Contribution to journalArticle

82 Scopus citations

Epoxyeicosatrienoic acid inhibition alters renal hemodynamics during pregnancy

Huang, H., Chang, H. H., Xu, Y., Reddy, D. S., Du, J., Zhou, Y., Dong, Z., Falck, J. R. & Wang, M-H., Dec 2006, In : Experimental Biology and Medicine. 231, 11, p. 1744-1752 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Expression, subcellular localization, and regulation of sigma receptor in retinal Müller cells

Jiang, G., Mysona, B., Dun, Y., Gnana-Prakasam, J. P., Pabla, N., Li, W., Dong, Z., Ganapathy, V. & Smith, S. B., Dec 2006, In : Investigative Ophthalmology and Visual Science. 47, 12, p. 5576-5582 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Prostaglandin D2 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in MDCK cells

Zhang, A., Dong, Z. & Yang, T., Dec 14 2006, In : American Journal of Physiology - Renal Physiology. 291, 6, p. F1332-F1342

Research output: Contribution to journalArticle

43 Scopus citations
56 Scopus citations