Find Research Projects

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A novel mechanism of coagulation in sickle cell disease

Brittain, J. E.

Project: Research project

Finished

Regulation of cilia by ceramide

Bieberich, E.

National Institutes of Health

9/30/159/29/16

Project: Research projectHigh Priority, Short Term Project Award

Cilia
Ceramides
Astrocytes
Proteins
Membrane Lipids

Multiplex Luminex glycan array for large scale analyses of glycan-binding proteins

She, J.

National Institutes of Health

9/9/156/30/17

Project: Research projectExploratory/Developmental Grants

Polysaccharides
Carrier Proteins
Glycomics
Type 1 Diabetes Mellitus
Blood Transfusion
Cerebral Hemorrhage
Extremities
AMP-Activated Protein Kinases
Stroke
Hematoma
Nephritis
Podocytes
Peptides
Glomerulonephritis
Endothelial Cells
Carotid Stenosis
Blood Vessels
Dementia
Leukoaraiosis
Vascular Dementia

Regulation of Notch signaling activity by mammalian Pins during neurogenesis

Du, Q.

National Institutes of Health

5/1/154/30/17

Project: Research projectExploratory/Developmental Grants

Neurogenesis
Asymmetric Cell Division
Neural Stem Cells
Brain
Vertebrates

NEUROMODULATION THERAPY FOR FECAL INCONTINENCE

Rao, S. S. C.

National Institutes of Health

4/1/153/31/17

Project: Research projectExploratory/Developmental Grants

Fecal Incontinence
Therapeutics
Lower Gastrointestinal Tract
Pelvic Floor
Muscle Strength

A Dietary Supplement As Adjunct Therapy In Castration-Resistant Prostate Cancer

Wu, D.

National Institutes of Health

3/1/152/29/16

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase I

Castration
Dietary Supplements
Prostatic Neoplasms
Therapeutics
Punicaceae

New Cell Desiccation Strategy Using Non-Isothermal Drying and Biophysical Models

Eroglu, A.

National Institutes of Health

2/1/151/31/17

Project: Research projectExploratory/Developmental Grants

Sugars
Drying
Diffusion barriers
Tissue engineering
Biophysics

Airway and Lung Vascular Remodeling in COPD

Su, Y.

National Institutes of Health

10/1/149/30/18

Project: Research projectNon-HHS Research Projects

Calpain
Chronic Obstructive Pulmonary Disease
Lung
Smoke
Tobacco
Butyrates
Niacin
Ulcerative Colitis
Dietary Fiber
Inflammation

Antigenic specificities of intestinal CD4+Foxp3+ T cells.

Ignatowicz, L.

National Institutes of Health

8/1/141/31/16

Project: Research projectHigh Priority, Short Term Project Award

Intestines
Epitopes
Anti-Bacterial Agents
T-Lymphocytes
Antigens
Atrophy
Brain-Derived Neurotrophic Factor
Depression
Glucocorticoids
Insulin
G-Protein-Coupled Receptors
GTP-Binding Proteins
Membrane Proteins
Single Molecule Imaging
Ligands

H3K9 Methylation and Pancreatic Cancer Chemoresistance

Liu, K.

National Institutes of Health

6/4/145/31/16

Project: Research projectExploratory/Developmental Grants

gemcitabine
Pancreatic Neoplasms
Methylation
Apoptosis
Regulator Genes

Epigenetic regulation of T-cell dysfunction in chronic lymphocytic leukemia

Shi, H.

National Institutes of Health

6/1/145/31/16

Project: Research projectExploratory/Developmental Grants

B-Cell Chronic Lymphocytic Leukemia
Epigenomics
T-Lymphocytes
Biomarkers
Neoplasms

Role of CD4+T cells in maintenance of intestinal homeostasis

Ignatowicz, L.

National Institutes of Health

4/1/143/31/18

Project: Research projectResearch Project

Homeostasis
Maintenance
T-Lymphocytes
Antigens
Lymphoid Tissue

Bad to the Bone: Age-related Increases in Serum SDF-1 Leads to Bone Loss with Age

Hill, W. D.

National Institutes of Health

1/1/1412/31/17

Project: Research projectNon-HHS Research Projects

Mesenchymal Stromal Cells
Osteogenesis
Bone and Bones
Osteoporosis
Serum

Function of Verticillin A in Suppression of MDSC and CRC Stem Cells

Liu, K.

National Institutes of Health

1/1/1412/31/17

Project: Research projectNon-HHS Research Projects

Neoplastic Stem Cells
Colorectal Neoplasms
Fluorouracil
DNA Methylation
Pharmaceutical Preparations
Campylobacter jejuni
Campylobacter
Biofilms
Virulence
Regulon

Mechanisms of Erbin regulation of remyelination

Mei, L.

National Institutes of Health

10/1/139/30/17

Project: Research projectNon-HHS Research Projects

Neuregulin-1
Myelin Sheath
Schwann Cells
Veterans
Axons

Role of NADPH Oxidase in TBI Pathology

Brann, D. W.

National Institutes of Health

10/1/139/30/17

Project: Research projectNon-HHS Research Projects

NADPH Oxidase
Pathology
Traumatic Brain Injury
Dementia
Veterans Health

Inflammation and bone loss with aging

Shi, X. M.

National Institutes of Health

9/30/136/30/18

Project: Research projectResearch Project

Osteitis
PPAR gamma
Fats
Bone and Bones
Bone Marrow
Messenger RNA
Kinesin
Dyneins
Cell Polarity
Protein Transport

Adipose inflammation mediates obesity-induced deficits in hippocampal plasticity

Stranahan, A. M.

National Institutes of Health

9/6/136/30/16

Project: Research projectResearch Scientist Development Award - Research & Training

Obesity
Inflammation
Research
Cognition
Dementia

NEUROMODULATOR INFLUENCES ON PREFRONTAL CORTICAL FUNCTION

Blake, D. T. & Constantinidis, C.

National Institutes of Health

9/1/136/30/18

Project: Research projectResearch Project

Cholinergic Agents
Neurotransmitter Agents
Prefrontal Cortex
Deep Brain Stimulation
Cognition

Programming dendritic cells to induce tolerogenic response and suppress brain inf

Manicassamy, S.

National Institutes of Health

8/15/134/30/15

Project: Research projectHigh Priority, Short Term Project Award

Catenins
Dendritic Cells
Autoimmune Experimental Encephalomyelitis
Brain
Multiple Sclerosis

The Role of Endothelin-1 in Sickle Cell Disease

Kutlar, A., Meiler, S. & Pollock, D.

National Institutes of Health

8/15/135/31/18

Project: Research projectResearch Project--Cooperative Agreements

Sickle Cell Anemia
Endothelin-1
Translational Medical Research
Research
Pain

Synaptic Circuitry in Stroke

Kirov, S. A.

National Institutes of Health

8/1/135/31/18

Project: Research projectHigh Priority, Short Term Project Award, Research Project

Stroke
Wounds and Injuries
Dendrites
Neuroglia
Synapses
Mesenchymal Stromal Cells
Mitochondria
Fibrosis
RNA
Lung

P53 inactivation on MDSC development and tumor progression

Cui, Y.

National Institutes of Health

7/1/134/30/18

Project: Research projectResearch Project

Tumor Microenvironment
Neoplasms
Inflammation
Carcinogenesis
Colonic Neoplasms
Phosphodiesterase 5 Inhibitors
Chemoprevention
Colonic Neoplasms
Colon
Epithelium

Engineering DNA nanoparticles to create immune tolerance

Mellor, A. L. & Mellor, A. L.

National Institutes of Health

6/15/135/31/17

Project: Research projectResearch Project

Immune Tolerance
Indoleamine-Pyrrole 2,3,-Dioxygenase
Nanoparticles
DNA
Interferons

LRP4 signaling in neuromuscular junction formation

Mei, L. & Rongsheng, J.

National Institutes of Health

6/1/135/31/18

Project: Research projectResearch Project

Neuromuscular Junction
Agrin
Motor Neurons
Muscles
Congenital Myasthenic Syndromes

NLRP3 inflammasome and TBI

Dhandapani, K. M.

National Institutes of Health

6/1/135/30/16

Project: Research projectSmall Research Grants

Inflammasomes
Brain Edema
Wounds and Injuries
Traumatic Brain Injury
Therapeutics

Gene Discovery in Familial Keratoconus

Liu, Y.

4/1/133/31/17

Project: Research projectResearch Project

Post-Traumatic Stress Disorders
Veterans
Phenotype
Wounds and Injuries
Costs and Cost Analysis

Remote Ischemic Conditioning:Translating Endogenous Neuroprotection in Embolic St

Hess, D. C.

National Institutes of Health

3/15/132/28/15

Project: Research projectExploratory/Developmental Grants

Stroke
Ischemic Postconditioning
Behavior Therapy
Reperfusion
Cerebrovascular Circulation

Modeling fracture prediction in spinal cord injury and disease

Carbone, L. D.

National Institutes of Health

12/1/1211/30/14

Project: Research projectNon-HHS Research Projects

Spinal Cord Diseases
Veterans
Spinal Cord Injuries
Bone Density
Photon Absorptiometry

Regulation of Aldosterone Production in the Adrenal

Bollag, W. B.

National Institutes of Health

10/1/129/30/16

Project: Research projectNon-HHS Research Projects

VLDL Lipoproteins
Aldosterone
Hypertension
Veterans
Obesity
Glioma
Stem Cells
Bone Marrow Cells
Angiogenesis Inducing Agents
Neoplasms
beta Catenin
Catenins
Dendritic Cells
Inflammation
Inflammatory Bowel Diseases
T-Lymphocytes
Recurrence
Drug Therapy
Neoplasms
Immunity

Novel Strategies for prevention of diabetic vascular dysfunction.

Dong, Y., Lucas, R., Mellor, A. L., Caldwell, R. B. & Caldwell, R. W.

National Institutes of Health

9/1/128/31/15

Project: Research projectResource-Related Research Projects

Blood Vessels
Type 2 Diabetes Mellitus
Indoleamine-Pyrrole 2,3,-Dioxygenase
Arginase
Cytokines
Idiopathic Pulmonary Fibrosis
Mesenchymal Stromal Cells
Exosomes
Bone Marrow
Lung Diseases

Molecular and Temporal Dissection of Habit Learning

Tsien, J. Z.

National Institutes of Health

9/1/125/31/17

Project: Research projectResearch Project

Habits
Dissection
Learning
N-Methyl-D-Aspartate Receptors
Dopaminergic Neurons

Genetic Analysis of Human First Trimester Trophoblast in Ongoing Pregnancies

Diamond, M. P. & Armant, D. R.

National Institutes of Health

8/1/127/31/15

Project: Research projectExploratory/Developmental Grants

Medical Genetics
Trophoblasts
First Pregnancy Trimester
Pregnancy
DNA

Calpain Activates Intracellular TGF-beta1 in Pulmonary Hypertension

Su, Y.

National Institutes of Health

8/1/126/30/15

Project: Research projectSmall Research Grants

Transforming Growth Factor beta1
Calpain
Pulmonary Hypertension
Pulmonary Artery
Lung