Cellular and Molecular Genetics of Keratoconus

Project: Research project

Project Details

Description

ABSTRACT Our long term goal is to identify and characterize genetic mutations involved in the pathogenesis of keratoconus (KC). KC is a bilateral, asymmetric corneal degeneration characterized by localized thinning and protrusion of the thinned cornea. KC leads to high myopia, irregular astigmatism, and cornea scarring. Although genetic factors contribute to KC pathogenesis, its genetic causes remain to be identified. Only mutations in the VSX1 and MIR184 genes are known to cause KC, but they account for
StatusNot started

Funding

  • National Eye Institute: $364,307.00
  • National Eye Institute: $403,407.00
  • National Eye Institute: $423,045.00
  • National Eye Institute: $31,031.00
  • National Eye Institute: $382,328.00

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