RANDOMIZED TRIAL ON THE CLINICAL MANAGEMENT OF

Project: Research project

Description

The Randomized Trial on the Clinical Management of ASCUS and LSIL of the Uterine Cervix is designed to: l) Determine whether human papillomavirus(HPV) testing can effectively triage women with a cytologic diagnosis of ASCUS (atypical squamous cells of undetermined significance) or LSIL (low-grade squamous intraepithelial lesion) 2) Develop clinical management guidelines and provide prognostic information for the ASCUS and LSIL diagnostic categories of the Bethesda System, and 3) Determine whether the cost of screening and treatment for the potential precursor lesions of cervical cancer can be reduced though improved triage. The Contractor shall be responsible for overseeing the quality of all aspects of the Trial involving colposcopy and the taking of cervical biopsies. Prior to enrollment, the Contractor shall optimize and standardize clinic colposcopic and biopsy procedures, equipment, and supplies. During the conduct of the Trial, the contractor shall monitor and optimize all aspects of the Protocol related to colposcopies and biopsies. The Contractor shall cooperate with the Study's Coordinating Unit, Clinical Centers, Quality Control Groups, consultants, and the National Cancer Institute Project Officers.
StatusFinished
Effective start/end date9/30/959/29/01

Funding

  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health

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Randomized Controlled Trials
Colposcopy
Triage
Biopsy
National Cancer Institute (U.S.)
Consultants
Cervix Uteri
Uterine Cervical Neoplasms
Quality Control
Health Care Costs
Guidelines
Equipment and Supplies
Control Groups
Squamous Intraepithelial Lesions of the Cervix
Atypical Squamous Cells of the Cervix

ASJC

  • Medicine(all)