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Article
43 Citations (Scopus)

Activation of NAD(P)H oxidase by lipid hydroperoxides: Mechanism of oxidant-mediated smooth muscle cytotoxicity

Li, W. G., Stoll, L. L., Rice, J. B., Xu, S. P., Miller, F. J., Chatterjee, P., Hu, L., Oberley, L. W., Spector, A. A. & Weintraub, N. L., Apr 1 2003, In : Free Radical Biology and Medicine. 34, 7, p. 937-946 10 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Lipid Peroxides
Cytotoxicity
Oxidants
Smooth Muscle
2 Citations (Scopus)

Activation of NADPH oxidase by β-Glucan from Phellinus baumii (Agaricomycetes) in RAW 264.7 cells

Sung, S. K., Batbayar, S., Lee, D. H. & Kim, H. W., Jan 1 2017, In : International Journal of Medicinal Mushrooms. 19, 11, p. 957-965 9 p.

Research output: Contribution to journalArticle

Glucans
NADPH Oxidase
Macrophages
Lipopolysaccharides
Acetates
116 Citations (Scopus)

Activation of NF-κB by bradykinin through a Gα(q)- and Gβγ-dependent pathway that involves phosphoinositide 3-kinase and Akt

Xie, P., Browning, D. D., Hay, N., Mackman, N. & Ye, R. D., Aug 11 2000, In : Journal of Biological Chemistry. 275, 32, p. 24907-24914 8 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Bradykinin
Phosphatidylinositols
Phosphotransferases
Chemical activation
10 Citations (Scopus)

Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors

Gaisina, I. N., Lee, S. H., Kaidery, N. A., Ben Aissa, M., Ahuja, M., Smirnova, N. N., Wakade, S., Gaisin, A., Bourassa, M. W., Ratan, R. R., Nikulin, S. V., Poloznikov, A. A., Thomas, B., Thatcher, G. R. J. & Gazaryan, I. G., May 16 2018, In : ACS Chemical Neuroscience. 9, 5, p. 894-900 7 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Chemical activation
Prolyl Hydroxylases
Acids
Aptitude
91 Citations (Scopus)

Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice

Kimbler, D. E., Shields, J., Yanasak, N., Vender, J. R. & Dhandapani, K. M., Jul 17 2012, In : PloS one. 7, 7, e41229.

Research output: Contribution to journalArticle

Brain Edema
edema
Brain
Chemical activation
brain
54 Citations (Scopus)
Phosphorylation
p38 Mitogen-Activated Protein Kinases
Lipopolysaccharides
Nitric Oxide
Neutrophils
24 Citations (Scopus)

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R. W., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Myeloid Cells
Immunotherapy
Cell Differentiation
Cross-Priming
5 Citations (Scopus)

Activation of particulate guanylyl cyclase by endothelins in cultured SV-40 transformed cat iris sphincter smooth muscle cells

Ding, K., Latimer, A. J. & Abdel-Latif, A. A., Dec 11 1998, In : Life sciences. 64, 3, p. 161-174 14 p.

Research output: Contribution to journalArticle

Endothelin-3
Guanylate Cyclase
Endothelins
Iris
Smooth Muscle Myocytes
13 Citations (Scopus)

Activation of PERK elicits memory impairment through inactivation of CREB and downregulation of PSD95 after traumatic brain injury

Sen, T., Gupta, R., Kaiser, H. & Sen, N., Jun 14 2017, In : Journal of Neuroscience. 37, 24, p. 5900-5911 12 p.

Research output: Contribution to journalArticle

Response Elements
Carrier Proteins
Phosphotransferases
Down-Regulation
Memory Disorders
56 Citations (Scopus)

Activation of peroxisome proliferator-activated receptor α by substituted urea-derived soluble epoxide hydrolase inhibitors

Fang, X., Hu, S., Watanabe, T., Weintraub, N. L., Snyder, G. D., Yao, J., Liu, Y., Shyy, J. Y. J., Hammock, B. D. & Spector, A. A., Jul 1 2005, In : Journal of Pharmacology and Experimental Therapeutics. 314, 1, p. 260-270 11 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Peroxisome Proliferator-Activated Receptors
Urea
lauric acid
Carboxylic Acids

Activation of platelet-derived growth factor (PDGF) receptor-operated Ca2+ channel via tyrosine kinase and ras in mesangial cells

Ma, H., Matsunaga, H., Li, B., Marrero, M. B., Eaton, D. C. & Ling, B. N., Dec 1 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Mesangial Cells
Platelet-Derived Growth Factor
Protein-Tyrosine Kinases
Chemical activation
14 Citations (Scopus)
Oxytocin
Calcium Channels
Vasopressins
Neurons
Baclofen
26 Citations (Scopus)

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., Feb 1 2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

RNA Precursors
Phosphorylation
Serine
Exons
Protein Splicing
28 Citations (Scopus)

Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes

Rutkai, I., Feher, A., Erdei, N., Henrion, D., Papp, Z., Edes, I., Koller, A., Kaley, G. & Bagi, Z., Jul 1 2009, In : Cardiovascular Research. 83, 1, p. 148-154 7 p.

Research output: Contribution to journalArticle

Dinoprostone
Type 2 Diabetes Mellitus
Blood Pressure
Arterioles
Prostaglandin Receptors
Enzyme activity
Protein Kinases
Muscle Cells
Protein Kinase C
Free Radicals
190 Citations (Scopus)

Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta

Jin, L., Ying, Z. & Webb, R. C., Oct 1 2004, In : American Journal of Physiology - Heart and Circulatory Physiology. 287, 4 56-4, p. H1495-H1500

Research output: Contribution to journalArticle

rho-Associated Kinases
Aorta
Reactive Oxygen Species
Xanthine Oxidase
Myosin-Light-Chain Phosphatase
25 Citations (Scopus)

Activation of Rho is Required for Ligand-independent Oncogenic Signaling by a Mutant Epidermal Growth Factor Receptor

Boerner, J. L., Danielsen, A., McManus, M. J. & Maihle, N. J., Feb 2 2001, In : Journal of Biological Chemistry. 276, 5, p. 3691-3695 5 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Phosphoproteins
Chemical activation
Ligands
Tyrosine
80 Citations (Scopus)

Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction

Brittain, J. E., Mlinar, K. J., Anderson, C. S., Orringer, E. P. & Parise, L. V., Jan 1 2001, In : Journal of Clinical Investigation. 107, 12, p. 1555-1562 8 p.

Research output: Contribution to journalArticle

Cell Adhesion
Integrins
Signal Transduction
Erythrocytes
Proteins
8 Citations (Scopus)

Activation of Snake in a serine protease cascade that defines the dorsoventral axis is atypical and pipe-independent in Drosophila embryos

Steen, P. W., Tian, S., Tully, S. E., Cravatt, B. F. & LeMosy, E., Aug 1 2010, In : FEBS Letters. 584, 16, p. 3557-3560 4 p.

Research output: Contribution to journalArticle

Snakes
Serine Proteases
Drosophila
Embryonic Structures
Chemical activation
28 Citations (Scopus)

Activation of the cGMP signaling pathway is essential in delaying oocyte aging in diabetes mellitus

Goud, A. P., Goud, P. T., Diamond, M. P., Gonik, B. & Abu-Soud, H. M., Sep 26 2006, In : Biochemistry. 45, 38, p. 11366-11378 13 p.

Research output: Contribution to journalArticle

Medical problems
Oocytes
Diabetes Mellitus
Aging of materials
Chemical activation
10 Citations (Scopus)

Activation of the endothelin system mediates pathological angiogenesis during ischemic retinopathy

Patel, C., Narayanan, S. P., Zhang, W., Xu, Z., Sukumari Ramesh, S., Dhandapani, K. M., Caldwell, R. W. & Caldwell, R. B., Jan 1 2014, In : American Journal of Pathology. 184, 11, p. 3040-3051 12 p.

Research output: Contribution to journalArticle

Pathologic Neovascularization
Endothelins
Oxygen
Physiologic Neovascularization
Vascular Endothelial Growth Factor A
33 Citations (Scopus)

Activation of the ET-1/ETA pathway contributes to erectile dysfunction associated with mineralocorticoid hypertension

Carneiro, F. S., Nunes, K. P., Giachini, F. R. C., Lima, V. V., Carneiro, Z. N., Nogueira, E. F., Leite, R., Ergul, A., Rainey, W. E., Webb, R. C. & Tostes, R. C., Jan 1 2008, In : Journal of Sexual Medicine. 5, 12, p. 2793-2807 15 p.

Research output: Contribution to journalArticle

Mineralocorticoids
Endothelin-1
Erectile Dysfunction
Desoxycorticosterone
Salts
29 Citations (Scopus)

Activation of the heat shock transcription factor by hypoxia in normal and tumor cell lines in vivo and in vitro

Giaccia, A. J., Auger, E. A., Koong, A., Terris, D. J., Minchinton, A. I., Hahn, G. M. & Brown, J. M., 1992, In : International Journal of Radiation Oncology, Biology, Physics. 23, 4, p. 891-897 7 p.

Research output: Contribution to journalArticle

hypoxia
Tumor Cell Line
cultured cells
tumors
shock
1303 Citations (Scopus)

Activation of the Iκb kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C. A., Pickart, C. & Chen, Z. J., Oct 13 2000, In : Cell. 103, 2, p. 351-361 11 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Polyubiquitin
Ubiquitin-Conjugating Enzymes
Phosphotransferases
Chemical activation
55 Citations (Scopus)

Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin

Banes, A. K. L., Shaw, S. M., Tawfik, A., Patel, B. P., Ogbi, S., Fulton, D. & Marrero, M. B., Apr 1 2005, In : American Journal of Physiology - Cell Physiology. 288, 4 57-4, p. C805-C812

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Muscle
Serotonin
Chemical activation
Receptor, Serotonin, 5-HT1B
4 Citations (Scopus)

Activation of the kinin system in the ovary during ovulation: role of endogenous progesterone.

Brann, D. W., Greenbaum, L. M., Mahesh, V. B. & Gao, X., Apr 29 2002, In : BMC Physiology. 2, 1, p. 1-6 6 p., 1.

Research output: Contribution to journalArticle

Kininogens
Kinins
Ovulation
Progesterone
Ovary
71 Citations (Scopus)
Matrix Metalloproteinase 13
Cyclic GMP-Dependent Protein Kinases
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinases
27 Citations (Scopus)
Retinal Degeneration
Molecular Chaperones
Retinal Diseases
Photoreceptor Cells
Retinal Cone Photoreceptor Cells

Activation of the nuclear regulatory factor, NF-κb, by reactive oxygen intermediates (ROI) and release of TNF-α from cultured vascular smooth muscle cells

Newman, W., Warejcka, D., Castresana, M., Dama, K., Dalton, M. & Ueper-Woodford, S., Dec 1 1998, In : Critical care medicine. 26, 1 SUPPL., p. A34

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Hypoxanthine
Oxygen
Xanthine Oxidase
32 Citations (Scopus)

Activation of the poly(ADP-ribose) polymerase pathway in human heart failure

Molnár, A., Tóth, A., Bagi, Z., Papp, Z., Édes, I., Vaszily, M., Galajda, Z., Papp, J. G., Varró, A., Szüts, V., Lacza, Z., Gerö, D. & Szabó, C., Jul 1 2006, In : Molecular Medicine. 12, 7-8, p. 143-152 10 p.

Research output: Contribution to journalArticle

Poly(ADP-ribose) Polymerases
Heart Failure
Oxidative Stress
Apoptosis Inducing Factor
Peroxynitrous Acid
34 Citations (Scopus)

Activation of the small GTPase Rac1 by cGMP-dependent protein kinase

Hou, Y., Ye, R. D. & Browning, D. D., Jan 1 2004, In : Cellular Signalling. 16, 9, p. 1061-1069 9 p.

Research output: Contribution to journalArticle

Cyclic GMP-Dependent Protein Kinases
Monomeric GTP-Binding Proteins
p38 Mitogen-Activated Protein Kinases
HEK293 Cells
Transfection
15 Citations (Scopus)

Activation of the Smooth Muscle-specific Telokin Gene by Thyrotroph Embryonic Factor (TEF)

Zhou, J., Hoggatt, A. M. & Herring, B. P., Apr 16 2004, In : Journal of Biological Chemistry. 279, 16, p. 15929-15937 9 p.

Research output: Contribution to journalArticle

Thyrotrophs
Smooth Muscle
Muscle
Genes
Chemical activation
36 Citations (Scopus)

Activation of the sonic hedgehog signaling controls human pulmonary arterial smooth muscle cell proliferation in response to hypoxia

Wang, G., Zhang, Z., Xu, Z., Yin, H., Bai, L., Ma, Z., DeCoster, M. A., Qian, G. & Wu, G., Dec 1 2010, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1803, 12, p. 1359-1367 9 p.

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Cell Proliferation
Lung
Hypoxia-Inducible Factor 1
Cell Hypoxia
34 Citations (Scopus)

Activation of the STING adaptor attenuates experimental autoimmune encephalitis

Lemos, H., Huang, L., Chandler, P. R., Mohamed, E., Souza, G. R., Li, L., Pacholczyk, G., Barber, G. N., Hayakawa, Y., Munn, D. H. & Mellor, A. L., Jun 15 2014, In : Journal of Immunology. 192, 12, p. 5571-5578 8 p.

Research output: Contribution to journalArticle

Nanoparticles
DNA
Genes
Autoimmunity
Myelin-Oligodendrocyte Glycoprotein
5 Citations (Scopus)

Activation of UDP-Galactose:Globotriaosylceramide α1–3-Galactosyltransferase during PC12D Cell Differentiation Induced by Galactosylceramide

Ariga, T., Yoshino, H., Ren, S., Pal, S., Katoh-Semba, R. & Yu, R. K., Jan 1 1993, In : Biochemistry. 32, 31, p. 7904-7908 5 p.

Research output: Contribution to journalArticle

Uridine Diphosphate Galactose
Galactosylceramides
Galactosyltransferases
Protein Kinase C
Cell Differentiation
15 Citations (Scopus)

Activation of urocanase from Pseudomonas putida by electronically excited triplet species

Venema, R. C. & Hug, D. H., Dec 1 1985, In : Journal of Biological Chemistry. 260, 22, p. 12190-12193 4 p.

Research output: Contribution to journalArticle

Urocanate Hydratase
Pseudomonas putida
Chemical activation
Rose Bengal
Energy Transfer
86 Citations (Scopus)

Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation

Guo, A. M., Arbab, A. S., Falck, J. R., Chen, P., Edwards, P. A., Roman, R. J. & Scicli, A. G., Apr 1 2007, In : Journal of Pharmacology and Experimental Therapeutics. 321, 1, p. 18-27 10 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Reactive Oxygen Species
Endothelial Cells
Cell Proliferation
NADPH Oxidase
75 Citations (Scopus)

Activation of Wnt signaling pathway by human papillomavirus E6 and E7 oncogenes in HPV16-positive oropharyngeal squamous carcinoma cells

Rampias, T., Boutati, E., Pectasides, E., Sasaki, C., Kountourakis, P., Weinberger, P. & Psyrri, A., Mar 1 2010, In : Molecular Cancer Research. 8, 3, p. 433-443 11 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Oncogenes
Squamous Cell Carcinoma
Oropharyngeal Neoplasms
26 Citations (Scopus)
Phenylephrine
Adrenergic Receptors
Protein Kinase C
Wounds and Injuries
Adrenergic Antagonists
9 Citations (Scopus)

Activation of α2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint

Jiao, K., Zeng, G., Niu, L. N., Yang, H. X., Ren, G. T., Xu, X. Y., Li, F. F., Tay, F. C. M. & Wang, M. Q., Jul 25 2016, In : Scientific Reports. 6, 30085.

Research output: Contribution to journalArticle

Temporomandibular Joint
Chondrocytes
Adrenergic Agents
Cartilage
Signal Transduction
330 Citations (Scopus)

Activation of β-catenin in dendritic cells regulates immunity versus tolerance in the intestine

Manicassamy, S., Reizis, B., Ravindran, R., Nakaya, H., Salazar-Gonzalez, R. M., Wang, Y. C. & Pulendran, B., Aug 13 2010, In : Science. 329, 5993, p. 849-853 5 p.

Research output: Contribution to journalArticle

Catenins
Dendritic Cells
Intestines
Immunity
Autoantigens
185 Citations (Scopus)

Activator of G protein signaling 3: A gatekeeper of cocaine sensitization and drug seeking

Bowers, M. S., McFarland, K., Lake, R. W., Peterson, Y. K., Lapish, C. C., Gregory, M. L., Lanier, S. M. & Kalivas, P. W., Apr 22 2004, In : Neuron. 42, 2, p. 269-281 13 p.

Research output: Contribution to journalArticle

Cocaine
GTP-Binding Proteins
Prefrontal Cortex
Pharmaceutical Preparations
Antisense Oligonucleotides
17 Citations (Scopus)

Active capping technology-New approaches for in situ remediation of contaminated sediments

Knox, A. S., Paller, M. H. & Roberts, J., Mar 1 2012, In : Remediation. 22, 2, p. 93-117 25 p.

Research output: Contribution to journalArticle

capping
Remediation
Sediments
remediation
Biopolymers
10 Citations (Scopus)

Active Gαq subunits and M3 acetylcholine receptors promote distinct modes of association of RGS2 with the plasma membrane

Clark, M. A., Sethi, P. R. & Lambert, N. A., Feb 20 2007, In : FEBS Letters. 581, 4, p. 764-770 7 p.

Research output: Contribution to journalArticle

Cholinergic Receptors
Cell membranes
RGS Proteins
Cell Membrane
Association reactions
5 Citations (Scopus)
Problem-Based Learning
Students
Kidney
Exercise
Hemorrhage
35 Citations (Scopus)

Active site directed inhibition of a cytosolic β-glucosidase from calf liver by bromoconduritol B epoxide and bromoconduritol F

Legler, G. & Bieberich, E., Jan 1 1988, In : Archives of Biochemistry and Biophysics. 260, 1, p. 437-442 6 p.

Research output: Contribution to journalArticle

Glucosidases
Liver
Catalytic Domain
Chemical beam epitaxy
Epoxy Compounds
56 Citations (Scopus)

Active site-directed inhibitors of Rhodococcus 20 S proteasome. Kinetics and mechanism

Mc Cormack, T., Baumeister, W., Grenier, L., Moomaw, C., Plamondon, L., Pramanik, B., Slaughter, C. A., Soucy, F., Stein, R., Zühl, F. & Dick, L., Oct 17 1997, In : Journal of Biological Chemistry. 272, 42, p. 26103-26109 7 p.

Research output: Contribution to journalArticle

Rhodococcus
Lactones
Proteasome Endopeptidase Complex
Catalytic Domain
Kinetics
2 Citations (Scopus)

Active Surveillance for Localized Prostate Cancer: No Increased Mortality, but Higher Rates of Clinical Progression

Ebell, M. H., Feb 1 2017, In : American family physician. 95, 3, 1 p.

Research output: Contribution to journalArticle

Watchful Waiting
Prostate-Specific Antigen
Survival Analysis
Prostatectomy
Prostatic Neoplasms
9 Citations (Scopus)

Actividades antioxidante y neutralizante de radicales libres del extracto metanólico de sida rhomboidea. Roxb determinadas por diferentes modelos in vitro

Translated title of the contribution: Antioxidant and free radical scavenging activity of sida rhomboidea. Roxb methanolic extract determined using different in vitro modelsThounaojam, M. C., Jadeja, R. N., Devkar, R. V. & Ramachandran, A. V., May 1 2010, In : Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas. 9, 3, p. 191-198 8 p.

Research output: Contribution to journalArticle

Sida
Inhibitory Concentration 50
Free Radicals
inhibitory concentration 50
Antioxidants
10 Citations (Scopus)

Activities of dicationic compounds against Trichomonas vaginalis

Crowell, A. L., Stephens, C. E., Kumar, A., Boykin, D. W. & Secor, W. E., Sep 1 2004, In : Antimicrobial Agents and Chemotherapy. 48, 9, p. 3602-3605 4 p.

Research output: Contribution to journalArticle

Trichomonas vaginalis
Metronidazole
Inhibitory Concentration 50
Parasites
4-nitroimidazole