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• 2014

  Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies

  Zhang, W., Gao, C., Konopleva, M., Chen, Y., Jacamo, R. O., Borthakur, G., Cortes, J. E., Ravandi, F., Ramachandran, A. & Andreeff, M., May 1 2014, In: Clinical Cancer Research. 20, 9, p. 2363-2374 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  37 Scopus citations
• 2013

  Salvage therapy using FLT3 inhibitors may improve long-term outcome of relapsed or refractory AML in patients with FLT3-ITD

  Takahashi, K., Kantarjian, H., Pemmaraju, N., Andreeff, M., Borthakur, G., Faderl, S., Garcia-Manero, G., Pierce, S., Luthra, R., Cardenas-Turanzas, M., Estrov, Z., Ravandi, F. & Cortes, J., Jun 2013, In: British Journal of Haematology. 161, 5, p. 659-666 8 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations
• 2021

  Phase 1 dose escalation trial of volasertib in combination with decitabine in patients with acute myeloid leukemia

  Cortes, J., Podoltsev, N., Kantarjian, H., Borthakur, G., Zeidan, A. M., Stahl, M., Taube, T., Fagan, N., Rajeswari, S. & Uy, G. L., Jan 2021, In: International Journal of Hematology. 113, 1, p. 92-99 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations
• 2008

  Favorable long-term follow-up results over 6 years for response, survival, and safety with imatinib mesylate therapy in chronic-phase chronic myeloid leukemia after failure of interferon-α treatment

  Hochhaus, A., Druker, B., Sawyers, C., Guilhot, F., Schiffer, C. A., Cortes, J., Niederwieser, D. W., Gambacorti, C., Stone, R. M., Goldman, J., Fischer, T., O'Brien, S. G., Reiffers, J. J., Mone, M., Krahnke, T., Talpaz, M. & Kantarjian, H. M., 2008, In: Blood. 111, 3, p. 1039-1043 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  195 Scopus citations
• 1999

  Combination of topotecan with cytarabine or etoposide in patients with refractory or relapsed acute myeloid leukemia: Results of a randomized phase I/II study

  Vey, N., Kantarjian, H., Beran, M., O'Brien, S., Cortes, J., Koller, C. & Estey, E., 1999, In: Investigational New Drugs. 17, 1, p. 89-95 7 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations
• 2011

  Mutant BCR-ABL clones in chronic myeloid leukemia

  Mathisen, M. S., Kantarjian, H. M., Cortes, J. & Jabbour, E., Mar 2011, In: Haematologica. 96, 3, p. 347-349 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
  16 Scopus citations
• 1999

  Granulocytic sarcoma of the pancreas: A report of two cases and literature review

  Ravandi-Kashani, F., Estey, E., Cortes, J., Medeiros, L. J. & Giles, F. J., 1999, In: Clinical and Laboratory Haematology. 21, 3, p. 219-224 6 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations
• 2021

  Ufbp1, a Key Player of Ufm1 Conjugation System, Protects Against Ketosis-Induced Liver Injury via Suppressing Smad3 Activation

  Chen, F., Sheng, L., Xu, C., Li, J., Ali, I., Li, H. & Cai, Y., Jul 8 2021, In: Frontiers in Cell and Developmental Biology. 9, 676789.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2012

  Nilotinib in patients with Ph + chronic myeloid leukemia in accelerated phase following imatinib resistance or intolerance: 24-month follow-up results

  Le Coutre, P. D., Giles, F. J., Hochhaus, A., Apperley, J. F., Ossenkoppele, G. J., Blakesley, R., Shou, Y., Gallagher, N. J., Baccarani, M., Cortes, J. & Kantarjian, H. M., Jun 2012, In: Leukemia. 26, 6, p. 1189-1194 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  71 Scopus citations
• 2005

  Phase I evaluation of a 40-kDa branched-chain long-acting pegylated IFN-α-2a with and without cytarabine in patients with chronic myelogenous leukemia

  Talpaz, M., Rakhit, A., Rittweger, K., O'Brien, S., Cortes, J., Fettner, S., Hooftman, L. & Kantarjian, H., Sep 1 2005, In: Clinical Cancer Research. 11, 17, p. 6247-6255 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  29 Scopus citations
• 2014

  Long non-coding RNA hotair is targeted and regulated by MIR-141 in human cancer cells

  Chiyomaru, T., Fukuhara, S., Saini, S., Majid, S., Deng, G., Shahryari, V., Chang, I., Tanaka, Y., Enokida, H., Nakagawa, M., Dahiya, R. & Yamamura, S., 2014, In: Journal of Biological Chemistry. 289, 18, p. 12550-12565 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  146 Scopus citations
• 2012

  How I treat newly diagnosed chronic phase CML

  Cortes, J. & Kantarjian, H., Aug 16 2012, In: Blood. 120, 7, p. 1390-1397 8 p.

  Research output: Contribution to journal › Article › peer-review
  88 Scopus citations
• 2016

  MicroRNAs and epithelial-mesenchymal transition in prostate cancer

  Sekhon, K., Bucay, N., Majid, S., Dahiya, R. & Saini, S., 2016, In: Oncotarget. 7, 41, p. 67597-67611 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  33 Scopus citations
• 2013

  CD30 expression in high-risk acute myeloid Leukemia and myelodysplastic syndromes

  Zheng, W., Medeiros, L. J., Hu, Y., Powers, L., Cortes, J. E., Ravandi-Kashani, F., Kantarjian, H. H. & Wang, S. A., Jun 2013, In: Clinical Lymphoma, Myeloma and Leukemia. 13, 3, p. 307-314 8 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Prognostic model to identify patients with myelofibrosis at the highest risk of transformation to acute myeloid Leukemia

  Quintás-Cardama, A., Kantarjian, H., Pierce, S., Cortes, J. & Verstovsek, S., Jun 2013, In: Clinical Lymphoma, Myeloma and Leukemia. 13, 3, p. 315-318.e2

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations
• 2007

  Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia

  Oki, Y., Kantarjian, H. M., Gharibyan, V., Jones, D., O'Brien, S., Verstovsek, S., Cortes, J., Morris, G. M., Garcia-Manero, G. & Issa, J. P. J., Mar 1 2007, In: Cancer. 109, 5, p. 899-906 8 p.

  Research output: Contribution to journal › Article › peer-review
  112 Scopus citations
• 2015

  Any Questions? An Application of Weick's Model of Organizing to Increase Student Involvement in the Large-Lecture Classroom

  Ledford, C. J. W., Saperstein, A. K., Cafferty, L. A., McClintick, S. H. & Bernstein, E. M., Apr 3 2015, In: Communication Teacher. 29, 2, p. 116-128 13 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations
• 2017

  Erratum: A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials (Leukemia (2017) 31 2 (318-324))

  Montalban-Bravo, G., Huang, X., Naqvi, K., Jabbour, E., Borthakur, G., DiNardo, C. D., Pemmaraju, N., Cortes, J., Verstovsek, S., Kadia, T., Daver, N., Wierda, W., Alvarado, Y., Konopleva, M., Ravandi, F., Estrov, Z., Jain, N., Alfonso, A., Brandt, M., Sneed, T. & 8 others, Chen, H. C., Yang, H., Bueso-Ramos, C., Pierce, S., Estey, E., Bohannan, Z., Kantarjian, H. M. & Garcia-Manero, G., Jul 1 2017, In: Leukemia. 31, 7, p. 1659 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
• 2018

  Critical factors to practicing medical acupuncture in family medicine: Patient and physician perspectives

  Ledford, C. J. W., Fisher, C. L., Moss, D. A. & Crawford, P. F., Mar 1 2018, In: Journal of the American Board of Family Medicine. 31, 2, p. 236-242 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Scopus citations
• 2005

  T-cell prolymphocytic leukemia: A single-institution experience

  Ravandi, F., O'Brien, S., Jones, D., Lerner, S., Faderl, S., Ferrajoli, A., Wierda, W., Garcia-Manero, G., Thomas, D., Koller, C., Verstovsek, S., Giles, F., Cortes, J., Herling, M., Kantarjian, H. & Keating, M., Nov 2005, In: Clinical Lymphoma and Myeloma. 6, 3, p. 234-239 6 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations
• 1991

  A conserved sequence element in ribonuclease III processing signals is not required for accurate in vitro enzymatic cleavage

  Chelladurai, B. S., Li, H. & Nicholson, A. W., Apr 25 1991, In: Nucleic Acids Research. 19, 8, p. 1759-1766 8 p.

  Research output: Contribution to journal › Article › peer-review
  45 Scopus citations
• 2015

  Phase II trial of ponatinib in patients with chronic myeloid leukemia resistant to one previous tyrosine kinase inhibitor

  Sanford, D., Kantarjtan, H., Skinner, J., Jabbour, E. & Cortes, J., 2015, In: Haematologica. 100, 12, p. e494-e495

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  16 Scopus citations

• Final results of a phase 2 trial of clofarabine and low-dose cytarabine alternating with decitabine in older patients with newly diagnosed acute myeloid leukemia

  Kadia, T. M., Faderl, S., Ravandi, F., Jabbour, E., Garcia-Manero, G., Borthakur, G., Ferrajoli, A., Konopleva, M., Burger, J., Huang, X., Wang, X., Pierce, S., Brandt, M., Feliu, J., Cortes, J. & Kantarjian, H., Jul 1 2015, In: Cancer. 121, 14, p. 2375-2382 8 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations
• 2008

  Molecular monitoring in chronic myeloid leukemia: Response to tyrosine kinase inhibitors and prognostic implications

  Jabbour, E., Cortes, J. E. & Kantarjian, H. M., May 15 2008, In: Cancer. 112, 10, p. 2112-2118 7 p.

  Research output: Contribution to journal › Review article › peer-review
  43 Scopus citations
• 2011

  New developments in the treatment of chronic myeloid leukemia and Philadelphia-positive acute lymphoblastic leukemia

  Fullmer, A., Kantarjian, H., Cortes, J. & Jabbour, E., Feb 2011, In: Leukemia and Lymphoma. 52, SUPPL. 1, p. 81-91 11 p.

  Research output: Contribution to journal › Review article › peer-review
  11 Scopus citations
• 2013

  Optimizing management of ruxolitinib in patients with myelofibrosis: The need for individualized dosing

  Mesa, R. A. & Cortes, J., 2013, In: Journal of Hematology and Oncology. 6, 1, 79.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  37 Scopus citations
• 2002

  Differences in CD33 intensity between various myeloid neoplasms

  Jilani, I., Estey, E., Huh, Y., Joe, Y., Manshouri, T., Yared, M., Giles, F., Kantarjian, H., Cortes, J., Thomas, D., Keating, M., Freireich, E. & Albitar, M., Oct 2002, In: American Journal of Clinical Pathology. 118, 4, p. 560-566 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  98 Scopus citations
• 2017

  Factors associated with risk of central nervous system relapse in patients with non-core binding factor acute myeloid leukemia

  Jabbour, E., Guastad Daver, N., Short, N. J., Huang, X., Chen, H. C., Maiti, A., Ravandi, F., Cortes, J., Abi Aad, S., Garcia-Manero, G., Estrov, Z., Kadia, T., O'Brien, S., Dabaja, B., Bueso-Ramos, C., Strati, P., Bivins, C., Pierce, S. & Kantarjian, H., Sep 2017, In: American Journal of Hematology. 92, 9, p. 924-928 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Scopus citations
• 2000

  Autoantibodies to Abl and Bcr proteins

  Talpaz, M., Qiu, X., Cheng, K., Cortes, J. E., Kantarjian, H. & Kurzrock, R., 2000, In: Leukemia. 14, 9, p. 1661-1666 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations
• 2008

  Omacetaxine mepesuccinate - A semisynthetic formulation of the natural antitumoral alkaloid homoharringtonine, for chronic myelocytic leukemia and other myeloid malignancies

  Quintás-Cardama, A. & Cortes, J., May 2008, In: IDrugs. 11, 5, p. 356-372 17 p.

  Research output: Contribution to journal › Review article › peer-review
  16 Scopus citations
• 2003

  Mylotarg, fludarabine, cytarabine (ara-C), and cyclosporine (MFAC) regimen as post-remission therapy in acute myelogenous leukemia

  Tsimberidou, A. M., Estey, E., Cortes, J. E., Garcia-Manero, G., Faderl, S., Verstovsek, S., Thomas, D. A., Ferrajoli, A., Keating, M. J., O'Brien, S., Kantarjian, H. M. & Giles, F. J., Dec 1 2003, In: Cancer Chemotherapy and Pharmacology. 52, 6, p. 449-452 4 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations
• 2017

  Donor type, in addition to transplantation in chronic phase and myeloablative conditioning, influence transplant survival for patients with advanced chronic myeloid leukemia in the era of tyrosine kinase inhibitors

  Kongtim, P., Adekola, K., Milton, D. R., Ramlal, R., Jimenez, A., Chen, J., Rondon, G., Ahmed, S., Kebriaei, P., Betul, O., Hosing, C. M., Popat, U., Khouri, I., Jabbour, E., Cortes, J. E., Kantarjian, H. M., Champlin, R. E. & Ciurea, S. O., Jul 1 2017, In: Leukemia. 31, 7, p. 1654-1657 4 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Scopus citations

• Clonal evolution and outcomes in myelofibrosis after ruxolitinib discontinuation

  Newberry, K. J., Patel, K., Masarova, L., Luthra, R., Manshouri, T., Jabbour, E., Bose, P., Daver, N., Cortes, J., Kantarjian, H. & Verstovsek, S., Aug 31 2017, In: Blood. 130, 9, p. 1125-1131 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  111 Scopus citations
• 2012

  Estimations of the increasing prevalence and plateau prevalence of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy

  Huang, X., Cortes, J. & Kantarjian, H., Jun 15 2012, In: Cancer. 118, 12, p. 3123-3127 5 p.

  Research output: Contribution to journal › Article › peer-review
  179 Scopus citations
• 2011

  Considerations in the management of patients with philadelphia chromosome-positive chronic myeloid leukemia receiving tyrosine kinase inhibitor therapy

  Kantarjian, H. & Cortes, J., Apr 20 2011, In: Journal of Clinical Oncology. 29, 12, p. 1512-1516 5 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  27 Scopus citations
• 2009

  Sustained durability of responses and improved progression-free and overall survival with imatinib treatment for accelerated phase and blast crisis chronic myeloid leukemia: Long-term follow-up of the STI571 0102 and 0109 trials

  Silver, R. T., Cortes, J., Waltzman, R., Mone, M. & Kantarjian, H., May 2009, In: Haematologica. 94, 5, p. 743-744 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  30 Scopus citations

• BCR-ABL truncation due to premature translation termination as a mechanism of resistance to kinase inhibitors

  Ma, W., Kantarjian, H., Yeh, C. H., Zhang, Z. J., Cortes, J. & Albitar, M., Apr 2009, In: Acta Haematologica. 121, 1, p. 27-31 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations
• 2006

  Allogeneic stem cell transplantation for patients with chronic myeloid leukemia and acute lymphocytic leukemia after Bcr-Abl kinase mutation-related imatinib failure

  Jabbour, E., Cortes, J., Kantarjian, H. M., Giralt, S., Jones, D., Jones, R., Giles, F., Andersson, B. S., Champlin, R. & De Lima, M., Aug 15 2006, In: Blood. 108, 4, p. 1421-1423 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  78 Scopus citations
• 2009

  Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera

  Quintás-Cardama, A., Kantarjian, H., Manshouri, T., Luthra, R., Estrov, Z., Pierce, S., Richie, M. A., Borthakur, G., Konopleva, M., Cortes, J. & Verstovsek, S., Nov 10 2009, In: Journal of Clinical Oncology. 27, 32, p. 5418-5424 7 p.

  Research output: Contribution to journal › Article › peer-review
  306 Scopus citations
• 2003

  Mitoxantrone and prolonged infusion gemcitabine as salvage therapy in patients with acute myelogenous leukemia

  Apostolidou, E., Estey, E., Cortes, J., Garcia-Manero, G., Faderl, S., Thomas, D., Tsimberidou, A., Kantarjian, H. & Giles, F. J., Apr 1 2003, In: Leukemia Research. 27, 4, p. 301-304 4 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations
• 2018

  Early results of lower dose dasatinib (50 mg daily) as frontline therapy for newly diagnosed chronic-phase chronic myeloid leukemia

  Naqvi, K., Jabbour, E., Skinner, J., Yilmaz, M., Ferrajoli, A., Bose, P., Thompson, P., Alvarado, Y., Jain, N., Takahashi, K., Burger, J., Estrov, Z., Borthakur, G., Pemmaraju, N., Paul, S., Cortes, J. & Kantarjian, H. M., Jul 1 2018, In: Cancer. 124, 13, p. 2740-2747 8 p.

  Research output: Contribution to journal › Article › peer-review
  33 Scopus citations
• 2012

  Molecular targeted therapy in acute myeloid leukemia

  Daver, N. & Cortes, J., Apr 2012, In: Hematology. 17, SUPPL. 1, p. S59-S62

  Research output: Contribution to journal › Review article › peer-review
  26 Scopus citations
• 2017

  MicroRNA-383 located in frequently deleted chromosomal locus 8p22 regulates CD44 in prostate cancer

  Bucay, N., Sekhon, K., Yang, T., Majid, S., Shahryari, V., Hsieh, C., Mitsui, Y., Deng, G., Tabatabai, Z. L., Yamamura, S., Calin, G. A., Dahiya, R., Tanaka, Y. & Saini, S., May 11 2017, In: Oncogene. 36, 19, p. 2667-2679 13 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations
• 2008

  Phosphorylation levels of BCR-ABL, CrkL, AKT and STAT5 in imatinib-resistant chronic myeloid leukemia cells implicate alternative pathway usage as a survival strategy

  Jilani, I., Kantarjian, H., Gorre, M., Cortes, J., Ottmann, O., Bhalla, K., Giles, F. J. & Albitar, M., Apr 2008, In: Leukemia Research. 32, 4, p. 643-649 7 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations
• 2015

  Effectiveness of homoharringtonine (omacetaxine mepesuccinate) for treatment of acute myeloid leukemia: A meta-analysis of Chinese studies

  Kantarjian, H., O'Brien, S., Jabbour, E., Barnes, G., Pathak, A. & Cortes, J., 2015, In: Clinical Lymphoma, Myeloma and Leukemia. 15, 1, p. 13-21 9 p.

  Research output: Contribution to journal › Review article › peer-review
  14 Scopus citations
• 2001

  Translocation t(17;18)(q10;q10): A new nonrandom chromosomal translocation of clonal evolution in chronic myeloid leukemia

  Ravandi, F., Hayes, K., Cortes, J., Albitar, M., Glassman, A., Talpaz, M. & Kantarjian, H. M., May 1 2001, In: Cancer. 91, 9, p. 1704-1708 5 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations
• 2013

  Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS)

  Saber, W., Cutler, C. S., Nakamura, R., Zhang, M. J., Atallah, E., Rizzo, J. D., Maziarz, R. T., Cortes, J., Kalaycio, M. E. & Horowitz, M. M., Sep 12 2013, In: Blood. 122, 11, p. 1974-1982 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  62 Scopus citations
• 2019

  Endothelial dysfunction in cystic fibrosis: Role of oxidative stress

  Tucker, M. A., Fox, B. M., Seigler, N., Rodriguez-Miguelez, P., Looney, J., Thomas, J., McKie, K. T., Forseen, C., Davison, G. W. & Harris, R. A., 2019, In: Oxidative medicine and cellular longevity. 2019, 1629638.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations
• 2009

  Synthetic tumor-specific breakpoint peptide vaccine in patients with chronic myeloid leukemia and minimal residual disease: A phase 2 trial

  Jain, N., Reuben, J. M., Kantarjian, H., Li, C., Gao, H., Lee, B. N., Cohen, E. N., Ebarb, T., Scheinberg, D. A. & Cortes, J., Sep 1 2009, In: Cancer. 115, 17, p. 3924-3934 11 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations
• 2003

  Advanced-phase chronic myeloid leukemia

  Cortes, J. & Kantarjian, H., Jan 2003, In: Seminars in Hematology. 40, 1, p. 79-86 8 p.

  Research output: Contribution to journal › Review article › peer-review
  52 Scopus citations