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• 2016

  Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury

  Shosha, E., Xu, Z., Yokota, H., Saul, A., Rojas, M., William Caldwell, R., Caldwell, R. B. & Priya Narayanan, S., 2016, In: Cell Death and Disease. 7, 11, e2483.

  Research output: Contribution to journal › Article › peer-review

  • Arginase
  • Reperfusion Injury
  • Ischemia
  • Electroretinography
  • Reperfusion
  23 Scopus citations
• 2018

  Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses

  Fouda, A. Y., Xu, Z., Shosha, E., Lemtalsi, T., Chen, J., Toque, H. A., Tritz, R., Cui, X., Stansfield, B. K., Huo, Y., Rodriguez, P. C., Smith, S. B., Caldwell, R. W., Narayanan, S. P. & Caldwell, R. B., Oct 1 2018, In: Cell Death and Disease. 9, 10, 1001.

  Research output: Contribution to journal › Article › peer-review

  • Arginase
  • Ischemia
  • Macrophages
  • Reperfusion Injury
  • Knockout Mice
  8 Scopus citations

• Mechanisms of diabetes-induced endothelial cell senescence: Role of arginase 1

  Shosha, E., Xu, Z., Priya Narayanan, S., Lemtalsi, T., Fouda, A. Y., Rojas, M., Xing, J., Fulton, D., William Caldwell, R. & Caldwell, R. B., Apr 17 2018, In: International journal of molecular sciences. 19, 4, 1215.

  Research output: Contribution to journal › Article › peer-review

  • Endothelial cells
  • Arginase
  • Medical problems
  • Cellular Senescence
  • Galactosidases
  8 Scopus citations
• 2017

  Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1

  Bhatta, A., Yao, L., Xu, Z., Toque, H. A., Chen, J., Atawia, R. T., Fouda, A. Y., Bagi, Z., Lucas, R., Caldwell, R. B. & Caldwell, R. W., Nov 1 2017, In: Cardiovascular Research. 113, 13, p. 1664-1676 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Arginase
  • Endothelial Cells
  • Obesity
  • Blood Vessels
  • Sucrose
  38 Scopus citations

• Netrin-1 is a novel regulator of vascular endothelial function in diabetes

  Toque, H. A., Fernandez-Flores, A., Mohamed, R., Caldwell, R. B., Ramesh, G. & Caldwell, R. W., Oct 2017, In: PloS one. 12, 10, e0186734.

  Research output: Contribution to journal › Article › peer-review

  • Netrin-1
  • Medical problems
  • diabetes
  • blood vessels
  • Blood Vessels
  12 Scopus citations
• 2016

  Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy

  Patel, C., Xu, Z., Shosha, E., Xing, J., Lucas, R., Caldwell, R. W., Caldwell, R. B. & Narayanan, S. P., Sep 1 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 9, p. 1628-1639 12 p.

  Research output: Contribution to journal › Article › peer-review

  • polyamine oxidase
  • Hyperoxia
  • Vascular System Injuries
  • Retinal Vessels
  • MDL 72527
  6 Scopus citations
• 2017

  Obesity-induced vascular inflammation involves elevated arginase activity

  Yao, L., Bhatta, A., Xu, Z., Chen, J., Toque, H. A., Chen, Y., Xu, Y., Bagi, Z., Lucas, R., Huo, Y., Caldwell, R. B. & Caldwell, R. W., Nov 2017, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 313, 5, p. R560-R571

  Research output: Contribution to journal › Article › peer-review

  • Arginase
  • Intra-Abdominal Fat
  • Obesity
  • Endothelial Cells
  • Inflammation
  12 Scopus citations

• Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock

  Subramani, K., Lu, S., Warren, M., Chu, X., Flores Toque, H. A., Caldwell, R. W., Diamond, M. P. & Raju, R. P., Dec 1 2017, In: Scientific reports. 7, 1, 2671.

  Research output: Contribution to journal › Article › peer-review

  • Hemorrhagic Shock
  • Resuscitation
  • Wounds and Injuries
  • Orphan Drug Production
  • Mitochondrial Membrane Potential
  8 Scopus citations
• 2020

  Arginase Pathway in Acute Retina and Brain Injury: Therapeutic Opportunities and Unexplored Avenues

  Fouda, A. Y., Eldahshan, W., Narayanan, S. P., Caldwell, R. W. & Caldwell, R. B., Mar 17 2020, In: Frontiers in Pharmacology. 11, 277.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Arginase
  • Brain Injuries
  • Retina
  • Nervous System Trauma
  • Traumatic Brain Injury
  2 Scopus citations
• 2018

  Arginase: A multifaceted enzyme important in health and disease

  Caldwell, R. W., Rodriguez, P. C., Toque, H. A., Priya Narayanan, S. & Caldwell, R. B., Apr 2018, In: Physiological reviews. 98, 2, p. 641-665 25 p.

  Research output: Contribution to journal › Review article › peer-review

  • Arginase
  • Enzymes
  • Health
  • Ornithine
  • Urea
  60 Scopus citations
• 2016

  Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model

  Bhatta, A., Sangani, R., Kolhe, R., Toque, H. A., Cain, M., Wong, A., Howie, N., Shinde, R., Elsalanty, M., Yao, L., Chutkan, N., Hunter, M., Caldwell, R. B., Isales, C., Caldwell, R. W. & Fulzele, S., Feb 15 2016, In: Molecular and Cellular Endocrinology. 422, p. 211-220 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Arginase
  • Nutrition
  • Deregulation
  • High Fat Diet
  • Sucrose
  11 Scopus citations
• 2020

  Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus

  Xia, Y., Zhang, Z., Lin, W., Yan, J., Zhu, C., Yin, D., He, S., Su, Y., Xu, N., Caldwell, R. W., Yao, L. & Chen, Y., Oct 1 2020, In: Neuropsychopharmacology. 45, 11, p. 1896-1908 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Arginase
  • Dentate Gyrus
  • Microglia
  • Schizophrenia
  • Mothers
  1 Scopus citations