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Activation of diverse signaling pathways by Ex-vivo delivery of multiple cytokines for myocardial repair

Konoplyannikov, M., Haider, K. H., Lai, V. K., Ahmed, R. P. H., Jiang, S. & Ashraf, M., Jan 15 2013, In : Stem Cells and Development. 22, 2, p. 204-215 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Activation of endoplasmic reticulum stress response following trauma-hemorrhage

Jian, B., Hsieh, C. H., Chen, J., Choudhry, M., Bland, K., Chaudry, I. & Raju, R., Nov 2008, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1782, 11, p. 621-626 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and l-citrulline formation

Schmidt, K., Martens-Lobenhoffer, J., Meinitzer, A., Graier, W. F., Torres, C. M., Venema, R. C. & Mayer, B., May 15 2010, In : Nitric Oxide - Biology and Chemistry. 22, 4, p. 281-289 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
16 Scopus citations

Activation of extracellular signal-regulated kinase 5 may play a neuroprotective role in hippocampal CA3/DG region after cerebral ischemia

Wang, R. M., Zhang, Q., Li, C. H. & Zhang, G. Y., May 1 2005, In : Journal of Neuroscience Research. 80, 3, p. 391-399 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains

Hossain, M. A., Shen, Y., Knudson, I., Thakur, S., Stees, J. R., Qiu, Y., Pace, B. S., Peterson, K. R. & Bungert, J., Jan 1 2016, In : Molecular Therapy - Nucleic Acids. 5, p. e378

Research output: Contribution to journalArticle

6 Scopus citations

Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion

Zhang, F., Li, C., Wang, R., Han, D., Zhang, Q., Zhou, C., Yu, H. M. & Zhang, G. Y., Dec 19 2007, In : Neuroscience. 150, 4, p. 938-949 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Activation of gelatinolytic/collagenolytic activity in dentin by self-etching adhesives

Nishitani, Y., Yoshiyama, M., Wadgaonkar, B., Breschi, L., Mannello, F., Mazzoni, A., Carvalho, R. M., Tjäderhane, L., Tay, F. R. & Pashley, D. H., Apr 2006, In : European Journal of Oral Sciences. 114, 2, p. 160-166 7 p.

Research output: Contribution to journalArticle

255 Scopus citations

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., Lee, J. R., Offermanns, S. & Ganapathy, V., Jan 16 2014, In : Immunity. 40, 1, p. 128-139 12 p.

Research output: Contribution to journalArticle

711 Scopus citations

Activation of G protein-coupled estrogen receptor induces endotheliumindependent relaxation of coronary artery smooth muscle

Yu, X., Ma, H., Barman, S. A., Liu, A. T., Sellers, M., Stallone, J. N., Prossnitz, E. R., White, R. E. & Han, G., Nov 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 5, p. E882-E888

Research output: Contribution to journalArticle

62 Scopus citations

Activation of hexosamine pathway impairs nitric oxide (NO)-dependent arteriolar dilations by increased protein O-GlcNAcylation

Beleznai, T. & Bagi, Z., Mar 2012, In : Vascular Pharmacology. 56, 3-4, p. 115-121 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Activation of IL-11/STAT3 pathway in preconditioned human skeletal myoblasts blocks apoptotic cascade under oxidant stress

Idris, N. M., Ashraf, M., Ahmed, R. P. H., Shujia, J. & Haider, K. H., Jan 2012, In : Regenerative Medicine. 7, 1, p. 47-57 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing

Boini, K. M., Xia, M., Abais, J. M., Li, G., Pitzer, A. L., Gehr, T. W. B., Zhang, Y. & Li, P. L., May 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 5, p. 836-845 10 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Activation of mesangial cell MAPK in response to homocysteine

Ingram, A. J., Krepinsky, J. C., James, L., Austin, R. C., Tang, D., Salapatek, A. M., Thai, K. & Scholey, J. W., Aug 2004, In : Kidney International. 66, 2, p. 733-745 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

Activation of midbrain structures by associative novelty and the formation of explicit memory in humans

Schott, B. H., Sellner, D. B., Lauer, C. J., Habib, R., Frey, J. U., Guderian, S., Heinze, H. J. & Düzel, E., Jul 1 2004, In : Learning and Memory. 11, 4, p. 383-387 5 p.

Research output: Contribution to journalArticle

92 Scopus citations

Activation of mitochondrial ATP-sensitive K+ channel for cardiac protection against ischemic injury is dependent on protein kinase C activity

Wang, Y., Hirai, K. & Ashraf, M., Oct 15 1999, In : Circulation research. 85, 8, p. 731-741 11 p.

Research output: Contribution to journalArticle

176 Scopus citations

Activation of mitochondrial K(ATP) channel elicits late preconditioning against myocardial infarction via protein kinase C signaling pathway

Takashi, E., Wang, Y. & Ashraf, M., Dec 3 1999, In : Circulation research. 85, 12, p. 1146-1153 8 p.

Research output: Contribution to journalArticle

147 Scopus citations

Activation of muscarinic acetylcholine receptors enhances the release of endogenous cannabinoids in the hippocampus

Kim, J., Isokawa, M., Ledent, C. & Alger, B. E., Dec 1 2002, In : Journal of Neuroscience. 22, 23, p. 10182-10191 10 p.

Research output: Contribution to journalArticle

Open Access
236 Scopus citations

Activation of myeloid TLR4 Mediates T lymphocyte polarization after traumatic brain injury

Braun, M., Vaibhav, K., Saad, N., Fatima, S., Brann, D. W., Vender, J. R., Wang, L. P., Hoda, M. N., Baban, B. & Dhandapani, K. M., May 1 2017, In : Journal of Immunology. 198, 9, p. 3615-3626 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Activation of NAD(P)H oxidase by lipid hydroperoxides: Mechanism of oxidant-mediated smooth muscle cytotoxicity

Li, W. G., Stoll, L. L., Rice, J. B., Xu, S. P., Miller, F. J., Chatterjee, P., Hu, L., Oberley, L. W., Spector, A. A. & Weintraub, N. L., Apr 1 2003, In : Free Radical Biology and Medicine. 34, 7, p. 937-946 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Activation of NADPH oxidase by β-Glucan from Phellinus baumii (Agaricomycetes) in RAW 264.7 cells

Sung, S. K., Batbayar, S., Lee, D. H. & Kim, H. W., Jan 1 2017, In : International Journal of Medicinal Mushrooms. 19, 11, p. 957-965 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Activation of NF-κB by bradykinin through a Gα(q)- and Gβγ-dependent pathway that involves phosphoinositide 3-kinase and Akt

Xie, P., Browning, D. D., Hay, N., Mackman, N. & Ye, R. D., Aug 11 2000, In : Journal of Biological Chemistry. 275, 32, p. 24907-24914 8 p.

Research output: Contribution to journalArticle

118 Scopus citations

Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia

Zhang, C., Boini, K. M., Xia, M., Abais, J. M., Li, X., Liu, Q. & Li, P. L., Jul 2012, In : Hypertension. 60, 1, p. 154-162 9 p.

Research output: Contribution to journalArticle

Open Access
105 Scopus citations

Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors

Gaisina, I. N., Lee, S. H., Kaidery, N. A., Ben Aissa, M., Ahuja, M., Smirnova, N. N., Wakade, S., Gaisin, A., Bourassa, M. W., Ratan, R. R., Nikulin, S. V., Poloznikov, A. A., Thomas, B., Thatcher, G. R. J. & Gazaryan, I. G., May 16 2018, In : ACS Chemical Neuroscience. 9, 5, p. 894-900 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice

Kimbler, D. E., Shields, J., Yanasak, N., Vender, J. R. & Dhandapani, K. M., Jul 17 2012, In : PloS one. 7, 7, e41229.

Research output: Contribution to journalArticle

98 Scopus citations
54 Scopus citations

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

33 Scopus citations

Activation of particulate guanylyl cyclase by endothelins in cultured SV-40 transformed cat iris sphincter smooth muscle cells

Ding, K. H., Latimer, A. J. & Abdel-Latif, A. A., Dec 11 1998, In : Life sciences. 64, 3, p. 161-174 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Activation of PERK elicits memory impairment through inactivation of CREB and downregulation of PSD95 after traumatic brain injury

Sen, T., Gupta, R., Kaiser, H. & Sen, N., Jun 14 2017, In : Journal of Neuroscience. 37, 24, p. 5900-5911 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Activation of peroxisome proliferator-activated receptor α by substituted urea-derived soluble epoxide hydrolase inhibitors

Fang, X., Hu, S., Watanabe, T., Weintraub, N. L., Snyder, G. D., Yao, J., Liu, Y., Shyy, J. Y. J., Hammock, B. D. & Spector, A. A., Jul 2005, In : Journal of Pharmacology and Experimental Therapeutics. 314, 1, p. 260-270 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Activation of platelet-derived growth factor (PDGF) receptor-operated Ca2+ channel via tyrosine kinase and ras in mesangial cells

Ma, H., Matsunaga, H., Li, B., Marrero, M. B., Eaton, D. C. & Ling, B. N., Dec 1 1996, In : FASEB Journal. 10, 3, p. A139

Research output: Contribution to journalArticle

14 Scopus citations

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., Feb 2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes

Rutkai, I., Feher, A., Erdei, N., Henrion, D., Papp, Z., Edes, I., Koller, A., Kaley, G. & Bagi, Z., Jul 2009, In : Cardiovascular Research. 83, 1, p. 148-154 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta

Jin, L., Ying, Z. & Webb, R. C., Oct 2004, In : American Journal of Physiology - Heart and Circulatory Physiology. 287, 4 56-4, p. H1495-H1500

Research output: Contribution to journalArticle

195 Scopus citations

Activation of Rho is Required for Ligand-independent Oncogenic Signaling by a Mutant Epidermal Growth Factor Receptor

Boerner, J. L., Danielsen, A., McManus, M. J. & Maihle, N. J., Feb 2 2001, In : Journal of Biological Chemistry. 276, 5, p. 3691-3695 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction

Brittain, J. E., Mlinar, K. J., Anderson, C. S., Orringer, E. P. & Parise, L. V., 2001, In : Journal of Clinical Investigation. 107, 12, p. 1555-1562 8 p.

Research output: Contribution to journalArticle

82 Scopus citations
Open Access
1 Scopus citations

Activation of Snake in a serine protease cascade that defines the dorsoventral axis is atypical and pipe-independent in Drosophila embryos

Steen, P. W., Tian, S., Tully, S. E., Cravatt, B. F. & LeMosy, E. K., Aug 2010, In : FEBS Letters. 584, 16, p. 3557-3560 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Activation of the cGMP signaling pathway is essential in delaying oocyte aging in diabetes mellitus

Goud, A. P., Goud, P. T., Diamond, M. P., Gonik, B. & Abu-Soud, H. M., Sep 26 2006, In : Biochemistry. 45, 38, p. 11366-11378 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Activation of the endothelin system mediates pathological angiogenesis during ischemic retinopathy

Patel, C., Narayanan, S. P., Zhang, W., Xu, Z., Sukumari-Ramesh, S., Dhandapani, K. M., Caldwell, R. W. & Caldwell, R. B., Nov 1 2014, In : American Journal of Pathology. 184, 11, p. 3040-3051 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Activation of the ET-1/ETA pathway contributes to erectile dysfunction associated with mineralocorticoid hypertension

Carneiro, F. S., Nunes, K. P., Giachini, F. R. C., Lima, V. V., Carneiro, Z. N., Nogueira, E. F., Leite, R., Ergul, A., Rainey, W. E., Clinton Webb, R. & Tostes, R. C., 2008, In : Journal of Sexual Medicine. 5, 12, p. 2793-2807 15 p.

Research output: Contribution to journalArticle

34 Scopus citations

Activation of the heat shock transcription factor by hypoxia in normal and tumor cell lines in vivo and in vitro

Giaccia, A. J., Auger, E. A., Koong, A., Terris, D. J., Minchinton, A. I., Hahn, G. M. & Brown, J. M., 1992, In : International Journal of Radiation Oncology, Biology, Physics. 23, 4, p. 891-897 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Activation of the Iκb kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C. & Chen, Z. J., Oct 13 2000, In : Cell. 103, 2, p. 351-361 11 p.

Research output: Contribution to journalArticle

1348 Scopus citations

Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin

Banes, A. K. L., Shaw, S. M., Tawfik, A., Patel, B. P., Ogbi, S., Fulton, D. & Marrero, M. B., Apr 2005, In : American Journal of Physiology - Cell Physiology. 288, 4 57-4, p. C805-C812

Research output: Contribution to journalArticle

60 Scopus citations

Activation of the kinin system in the ovary during ovulation: role of endogenous progesterone.

Brann, D. W., Greenbaum, L. M., Mahesh, V. B. & Gao, X., Apr 29 2002, In : BMC Physiology. 2, 1, p. 1-6 6 p., 1.

Research output: Contribution to journalArticle

5 Scopus citations
74 Scopus citations
35 Scopus citations

Activation of the nuclear regulatory factor, NF-κb, by reactive oxygen intermediates (ROI) and release of TNF-α from cultured vascular smooth muscle cells

Newman, W., Warejcka, D., Castresana, M., Dama, K., Dalton, M. & Ueper-Woodford, S., Dec 1 1998, In : Critical care medicine. 26, 1 SUPPL., p. A34

Research output: Contribution to journalArticle