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2019
Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice
Oseghale, A. R., Zhu, X., Li, B., Peterson, K. R., Nudelman, A., Rephaeli, A., Xu, H. & Pace, B. S., Nov 2019, In: Blood Cells, Molecules, and Diseases. 79, 102345.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Mechanisms of NRF2 activation to mediate fetal hemoglobin induction and protection against oxidative stress in sickle cell disease
Zhu, X., Oseghale, A. R., Nicole, L. H., Li, B. & Pace, B. S., Feb 1 2019, In: Experimental Biology and Medicine. 244, 2, p. 171-182 12 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease
Li, B., Zhu, X., Ward, C. M., Starlard-Davenport, A., Takezaki, M., Berry, A., Ward, A., Wilder, C., Neunert, C., Kutlar, A. & Pace, B. S., Feb 2019, In: Experimental Hematology. 70, p. 85-96.e5Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
MIR29B mediates epigenetic mechanisms of HBG gene activation
Starlard-Davenport, A., Smith, A., Vu, L., Li, B. & Pace, B. S., Jul 2019, In: British Journal of Haematology. 186, 1, p. 91-100 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2018
Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain
Li, B., Zhu, X., Hossain, M. A., Guy, C. R., Xu, H., Bungert, J. & Pace, B. S., Aug 31 2018, In: Haematologica. 103, 9, p. e384-e387Research output: Contribution to journal › Letter › peer-review
4 Scopus citations -
2017
NRF2 mediates γ-globin gene regulation and fetal hemoglobin induction in human erythroid progenitors
Zhu, X., Li, B. & Pace, B. S., Jul 31 2017, In: Haematologica. 102, 8, p. e285-e288Research output: Contribution to journal › Letter › peer-review
12 Scopus citations -
2016
Original Research: Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells
Ward, C. M., Li, B. & Pace, B. S., 2016, In: Experimental Biology and Medicine. 241, 7, p. 719-729 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Personalized chemotherapy of tumor disease based on system modeling
Li, B., 2016, Frontiers in Drug Design and Discovery. 1 ed. Bentham Science Publishers B.V., p. 223-247 25 p. (Frontiers in Drug Design and Discovery; vol. 7, no. 1).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2015
Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease
Pace, B. S., Liu, L., Li, B. & Makala, L. H., Aug 19 2015, In: Experimental Biology and Medicine. 240, 8, p. 1050-1064 15 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Novel inducers of fetal globin identified through high throughput screening (HTS) are active in vivo in anemic baboons and transgenic mice
Boosalis, M. S., Sangerman, J. I., White, G. L., Wolf, R. F., Shen, L., Dai, Y., White, E., Makala, L. H., Li, B., Pace, B. S., Nouraie, M., Faller, D. V. & Perrine, S. P., Dec 1 2015, In: PloS one. 10, 12, 0144660.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Single-cell next-generation sequencing and its applications in cancer biology
Li, B., Zhang, X. & Zheng, J., Jan 1 2015, Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides. Springer International Publishing, p. 1-18 18 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
2014
A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies
Peterson, K. R., Costa, F. C., Fedosyuk, H., Neades, R. Y., Chazelle, A. M., Zelenchuk, L., Fonteles, A. H., Dalal, P., Roy, A., Chaguturu, R., Li, B. & Pace, B. S., Sep 16 2014, In: PloS one. 9, 9, e107006.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Characterization of transcription factor networks involved in umbilical cord blood CD34+ stem cells-derived erythropoiesis
Li, B., Ding, L., Yang, C., Kang, B., Liu, L., Story, M. D. & Pace, B. S., Sep 2014, In: PloS one. 9, 9, e0107133.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina.
Promsote, W., Makala, L., Li, B., Smith, S. B., Singh, N., Ganapathy, V., Pace, B. S. & Martin, P. M., Aug 2014, In: Investigative ophthalmology & visual science. 55, 8, p. 5382-5393 12 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
2012
Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation
Li, B., Ding, L., Li, W., Story, M. D. & Pace, B. S., Apr 26 2012, In: BMC Genomics. 13, 1, 153.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
2011
Gene expression and pathway analysis of quiescent CD8+ T cells from liver cancer, liver sinusoid and peripheral blood: Study on toxicogenomics and prevention targeting
Wang, Z., Hu, H., Zheng, J. & Li, B., Dec 27 2011, Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011. p. 72-77 6 p. 6089810. (Proceedings - 2011 11th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2011).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution