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  • David H Munn
2020

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

Yu, M., Guo, G., Huang, L., Deng, L., Chang, C. S., Achyut, B. R., Canning, M., Xu, N., Arbab, A. S., Bollag, R. J., Rodriguez, P. C., Mellor, A. L., Shi, H., Munn, D. H. & Cui, Y., Dec 1 2020, In : Nature communications. 11, 1, 515.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
3 Scopus citations

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Thangavelu, G., Du, J., Paz, K. G., Loschi, M., Zaiken, M. C., Flynn, R., Taylor, P. A., Kirchmeier, A. K., Panoskaltsis-Mortari, A., Luznik, L., MacDonald, K. P., Hill, G. R., Maillard, I., Munn, D. H., Serody, J. S., Murphy, W. J., Miklos, D., Cutler, C. S., Koreth, J., Antin, J. H. & 5 others, Soiffer, R. J., Ritz, J., Dahlberg, C., Miller, A. T. & Blazar, B. R., Jan 1 2020, In : Blood. 135, 1, p. 28-40 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

Mohamed, E., Sierra, R. A., Trillo-Tinoco, J., Cao, Y., Innamarato, P., Payne, K. K., de Mingo Pulido, A., Mandula, J., Zhang, S., Thevenot, P., Biswas, S., Abdalla, S. K., Costich, T. L., Hänggi, K., Anadon, C. M., Flores, E. R., Haura, E. B., Mehrotra, S., Pilon-Thomas, S., Ruffell, B. & 4 others, Munn, D. H., Cubillos-Ruiz, J. R., Conejo-Garcia, J. R. & Rodriguez, P. C., Apr 14 2020, In : Immunity. 52, 4, p. 668-682.e7

Research output: Contribution to journalArticle

3 Scopus citations
2019

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Koehn, B. H., Saha, A., McDonald-Hyman, C., Loschi, M., Thangavelu, G., Ma, L., Zaiken, M., Dysthe, J., Krepps, W., Panthera, J., Hippen, K., Jameson, S. C., Miller, J. S., Cooper, M. A., Farady, C. J., Iwawaki, T., Ting, J. P. Y., Serody, J. S., Murphy, W. J., Hill, G. R. & 5 others, Murray, P. J., Bronte, V., Munn, D. H., Zeiser, R. & Blazar, B. R., Nov 7 2019, In : Blood. 134, 19, p. 1670-1682 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Thangavelu, G., Lee, Y. C., Loschi, M., Melanie Schaechter, K., Feser, C. J., Koehn, B. H., Nowak, E. C., Zeiser, R., Serody, J. S., Murphy, W. J., Munn, D. H., Chambon, P., Noelle, R. J. & Blazar, B. R., May 1 2019, In : Journal of Immunology. 202, 9, p. 2795-2805 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

Saha, A., Taylor, P. A., Lees, C. J., Panoskaltsis-Mortari, A., Osborn, M. J., Feser, C. J., Thangavelu, G., Melchinger, W., Refaeli, Y., Hill, G. R., Munn, D. H., Murphy, W. J., Serody, J. S., Maillard, I., Kreymborg, K., van den Brink, M., Dong, C., Huang, S., Zang, X., Allison, J. P. & 2 others, Zeiser, R. & Blazar, B. R., 2019, In : JCI Insight. 4, 19, e127716.

Research output: Contribution to journalArticle

Open Access

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Cao, Y., Trillo-Tinoco, J., Sierra, R. A., Anadon, C., Dai, W., Mohamed, E., Cen, L., Costich, T. L., Magliocco, A., Marchion, D., Klar, R., Michel, S., Jaschinski, F., Reich, R. R., Mehrotra, S., Cubillos-Ruiz, J. R., Munn, D. H., Conejo-Garcia, J. R. & Rodriguez, P. C., Dec 1 2019, In : Nature communications. 10, 1, 1280.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment

Halaby, M. J., Hezaveh, K., Lamorte, S., Ciudad, M. T., Kloetgen, A., MacLeod, B. L., Guo, M., Chakravarthy, A., Medina, T. D. S., Ugel, S., Tsirigos, A., Bronte, V., Munn, D. H., Pugh, T. J., De Carvalho, D. D., Butler, M. O., Ohashi, P. S., Brooks, D. G. & McGaha, T. L., Dec 13 2019, In : Science immunology. 4, 42

Research output: Contribution to journalArticle

5 Scopus citations

Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression (Nature Communications, (2019), 10, 1, (1280), 10.1038/s41467-019-09263-1)

Cao, Y., Trillo-Tinoco, J., Sierra, R. A., Anadon, C., Dai, W., Mohamed, E., Cen, L., Costich, T. L., Magliocco, A., Marchion, D., Klar, R., Michel, S., Jaschinski, F., Reich, R. R., Mehrotra, S., Cubillos-Ruiz, J. R., Munn, D. H., Conejo-Garcia, J. R. & Rodriguez, P. C., Dec 1 2019, In : Nature communications. 10, 1, 3680.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

Paz, K., Flynn, R., Du, J., Tannheimer, S., Johnson, A. J., Dong, S., Stark, A. K., Okkenhaug, K., Panoskaltsis-Mortari, A., Sage, P. T., Sharpe, A. H., Luznik, L., Ritz, J., Soiffer, R. J., Cutler, C. S., Koreth, J., Antin, J. H., Miklos, D. B., MacDonald, K. P., Hill, G. R. & 10 others, Maillard, I., Serody, J. S., Murphy, W. J., Munn, D. H., Feser, C., Zaiken, M., Vanhaesebroeck, B., Turka, L. A., Byrd, J. C. & Blazar, B. R., Jun 2019, In : American Journal of Transplantation. 19, 6, p. 1820-1830 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

33 Scopus citations

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

Habtetsion, T., Ding, Z-C., Pi, W., Li, T., Lu, C., Chen, T., Xi, C., Spartz, H., Liu, K., Hao, Z., Mivechi, N. F., Huo, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Aug 7 2018, In : Cell Metabolism. 28, 2, p. 228-242.e6

Research output: Contribution to journalArticle

10 Scopus citations

Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans article

Shinde, R., Hezaveh, K., Halaby, M. J., Kloetgen, A., Chakravarthy, A., Da Silva Medina, T., Deol, R., Manion, K. P., Baglaenko, Y., Eldh, M., Lamorte, S., Wallace, D., Chodisetti, S. B., Ravishankar, B., Liu, H., Chaudhary, K., Munn, D. H., Tsirigos, A., Madaio, M., Gabrielsson, S. & 4 others, Touma, Z., Wither, J., De Carvalho, D. D. & McGaha, T. L., Jun 1 2018, In : Nature Immunology. 19, 6, p. 571-582 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors

Nayak-Kapoor, A., Hao, Z., Sadek, R., Dobbins, R., Marshall, L., Vahanian, N. N., Jay Ramsey, W., Kennedy, E., Mautino, M. R., Link, C. J., Lin, R. S., Royer-Joo, S., Liang, X., Salphati, L., Morrissey, K. M., Mahrus, S., McCall, B., Pirzkall, A., Munn, D. H., Janik, J. E. & 1 others, Khleif, S. N., Jun 20 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 61.

Research output: Contribution to journalArticle

29 Scopus citations

The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells

Munn, D. H., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 570-572 3 p.

Research output: Contribution to journalReview article

8 Scopus citations

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

McDonald-Hyman, C., Muller, J. T., Loschi, M., Thangavelu, G., Saha, A., Kumari, S., Reichenbach, D. K., Smith, M. J., Zhang, G., Koehn, B. H., Lin, J., Mitchell, J. S., Fife, B. T., Panoskaltsis-Mortari, A., Feser, C. J., Kirchmeier, A. K., Osborn, M. J., Hippen, K. L., Kelekar, A., Serody, J. S. & 6 others, Turka, L. A., Munn, D. H., Chi, H., Neubert, T. A., Dustin, M. L. & Blazar, B. R., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4604-4621 18 p.

Research output: Contribution to journalArticle

8 Scopus citations

Treg Destabilization and reprogramming: Implications for cancer immunotherapy

Munn, D. H., Sharma, M. D. & Johnson, T. S., Sep 15 2018, In : Cancer Research. 78, 18, p. 5191-5199 9 p.

Research output: Contribution to journalReview article

22 Scopus citations
2017

Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells

Ding, Z-C., Habtetsion, T., Cao, Y., Li, T., Liu, C., Kuczma, M., Chen, T., Hao, Z., Bryan, L. J., Munn, D. H. & Zhou, G., Dec 1 2017, In : Scientific reports. 7, 1, 12168.

Research output: Contribution to journalArticle

9 Scopus citations

A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Mangaonkar, A., Mondal, A. K., Fulzule, S., Pundkar, C., Park, E. J., Jillella, A., Kota, V., Xu, H., Savage, N. M., Shi, H., Munn, D. & Kolhe, R., Dec 1 2017, In : Scientific reports. 7, 1, 12892.

Research output: Contribution to journalArticle

12 Scopus citations

Chemo-immunotherapy: Role of indoleamine 2,3-dioxygenase in defining immunogenic versus tolerogenic cell death in the tumor microenvironment

Johnson, T. S., Mcgaha, T. & Munn, D. H., 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 91-104 14 p. (Advances in Experimental Medicine and Biology; vol. 1036).

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment

Munn, D. H., Sharma, M. D., Johnson, T. S. & Rodriguez, P., Aug 1 2017, In : Cancer Immunology, Immunotherapy. 66, 8, p. 1049-1058 10 p.

Research output: Contribution to journalReview article

17 Scopus citations

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines

Hippen, K. L., O'Connor, R. S., Lemire, A. M., Saha, A., Hanse, E. A., Tennis, N. C., Merkel, S. C., Kelekar, A., Riley, J. L., Levine, B. L., June, C. H., Turka, L. A., Kean, L. S., MacMillan, M. L., Miller, J. S., Wagner, J. E., Munn, D. H. & Blazar, B. R., Dec 2017, In : American Journal of Transplantation. 17, 12, p. 3098-3113 16 p.

Research output: Contribution to journalArticle

14 Scopus citations

Overcoming immune suppression in the tumor microenvironment: Implications for multi-modal therapy

Johnson, T. S. & Munn, D. H., Jan 1 2017, Immunotherapy for Pediatric Malignancies. Springer International Publishing, p. 13-38 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Promoter methylation modulates indoleamine 2,3-dioxygenase 1 induction by activated T cells in human breast cancers

Noonepalle, S. K., Gu, F., Lee, E. J., Choi, J. H., Han, Q., Kim, J., Ouzounova, M., Shull, A. Y., Pei, L., Hsu, P. Y., Kolhe, R., Shi, F., Choi, J., Chiou, K., Huang, T. H. M., Korkaya, H., Deng, L., Xin, H. B., Huang, S., Thangaraju, M. & 5 others, Sreekumar, A., Ambs, S., Tang, S. C., Munn, D. H. & Shi, H., Apr 2017, In : Cancer Immunology Research. 5, 4, p. 330-344 15 p.

Research output: Contribution to journalArticle

11 Scopus citations
2016

Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity

Hong, Y., Manoharan, I., Suryawanshi, A., Shanmugam, A., Swafford, D., Ahmad, S., Chinnadurai, R., Manicassamy, B., He, Y., Mellor, A. L., Thangaraju, M., Munn, D. H. & Manicassamy, S., Apr 2 2016, In : OncoImmunology. 5, 4

Research output: Contribution to journalArticle

26 Scopus citations

IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

Munn, D. H. & Mellor, A. L., Mar 1 2016, In : Trends in Immunology. 37, 3, p. 193-207 15 p.

Research output: Contribution to journalReview article

322 Scopus citations

IL-7 signaling imparts polyfunctionality and stemness potential to CD4+ T cells

Ding, Z-C., Liu, C., Cao, Y., Habtetsion, T., Kuczma, M., Pi, W., Kong, H., Cacan, E., Greer, S. F., Cui, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Jun 2 2016, In : OncoImmunology. 5, 6, e1171445.

Research output: Contribution to journalArticle

9 Scopus citations

Immune suppressive mechanisms in the tumor microenvironment

Munn, D. H. & Bronte, V., Apr 1 2016, In : Current Opinion in Immunology. 39, p. 1-6 6 p.

Research output: Contribution to journalReview article

199 Scopus citations

MiR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

Lu, Y., Hippen, K. L., Lemire, A. L., Gu, J., Wang, W., Ni, X., Ranganathan, P., Levine, B. L., Riley, J. L., June, C. H., Turka, L. A., Munn, D. H., Garzon, R., Lu, L. & Blazar, B. R., Sep 8 2016, In : Blood. 128, 10, p. 1424-1435 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

Saha, A., O'Connor, R. S., Thangavelu, G., Lovitch, S. B., Dandamudi, D. B., Wilson, C. B., Vincent, B. G., Tkachev, V., Pawlicki, J. M., Furlan, S. N., Kean, L. S., Aoyama, K., Taylor, P. A., Panoskaltsis-Mortari, A., Foncea, R., Ranganathan, P., Devine, S. M., Burrill, J. S., Guo, L., Sacristan, C. & 15 others, Snyder, N. W., Blair, I. A., Milone, M. C., Dustin, M. L., Riley, J. L., Bernlohr, D. A., Murphy, W. J., Fife, B. T., Munn, D. H., Miller, J. S., Serody, J. S., Freeman, G. J., Sharpe, A. H., Turka, L. A. & Blazar, B. R., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2642-2660 19 p.

Research output: Contribution to journalArticle

46 Scopus citations

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation

Lemos, H., Mohamed, E., Huang, L., Ou, R., Pacholczyk, G., Arbab, A. S., Munn, D. & Mellor, A. L., Apr 15 2016, In : Cancer Research. 76, 8, p. 2076-2081 6 p.

Research output: Contribution to journalArticle

85 Scopus citations

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

Flynn, R., Paz, K., Du, J., Reichenbach, D. K., Taylor, P. A., Panoskaltsis-Mortari, A., Vulic, A., Luznik, L., MacDonald, K. K. P., Hill, G. R., Nyuydzefe, M. S., Weiss, J. M., Chen, W., Trzeciak, A., Serody, J. S., Aguilar, E. G., Murphy, W. J., Maillard, I., Munn, D. H., Koreth, J. & 6 others, Cutler, C. S., Antin, J. H., Ritz, J., Waksal, S. D., Zanin-Zhorov, A. & Blazar, B. R., Apr 28 2016, In : Blood. 127, 17, p. 2144-2154 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

McDonald-Hyman, C., Flynn, R., Panoskaltsis-Mortari, A., Peterson, N., MacDonald, K. P. A., Hill, G. R., Luznik, L., Serody, J. S., Murphy, W. J., Maillard, I., Munn, D. H., Turka, L. A., Koreth, J., Cutler, C. S., Soiffer, R. J., Antin, J. H., Ritz, J. & Blazar, B. R., Aug 18 2016, In : Blood. 128, 7, p. 1013-1017 5 p.

Research output: Contribution to journalArticle

46 Scopus citations

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

Huang, L., Ou, R., Rabelo de Souza, G., Cunha, T. M., Lemos, H., Mohamed, E., Li, L., Pacholczyk, G., Randall, J., Munn, D. H. & Mellor, A. L., May 2016, In : PLoS Pathogens. 12, 5, e1005615.

Research output: Contribution to journalArticle

19 Scopus citations
2015

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

Veenstra, R. G., Flynn, R., Kreymborg, K., McDonald-Hyman, C., Saha, A., Taylor, P. A., Osborn, M. J., Panoskaltsis-Mortari, A., Schmitt-Graeff, A., Lieberknecht, E., Murphy, W. J., Serody, J. S., Munn, D. H., Freeman, G. J., Allison, J. P., Mak, T. W., Van Brink, M. D., Zeiser, R. & Blazar, B. R., 2015, In : Blood. 125, 21, p. 3335-3346 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Canonical Wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation

Suryawanshi, A., Manoharan, I., Hong, Y., Swafford, D., Majumdar, T., Taketo, M. M., Manicassamy, B., Koni, P. A., Thangaraju, M., Sun, Z., Mellor, A. L., Munn, D. H. & Manicassamy, S., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 3295-3304 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Koehn, B. H., Apostolova, P., Haverkamp, J. M., Miller, J. S., McCullar, V., Tolar, J., Munn, D. H., Murphy, W. J., Brickey, W. J., Serody, J. S., Gabrilovich, D. I., Bronte, V., Murray, P. J., Ting, J. P. Y., Zeiser, R. & Blazar, B. R., Sep 24 2015, In : Blood. 126, 13, p. 1621-1628 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells

Sharma, M. D., Shinde, R., McGaha, T. L., Huang, L., Holmgaard, R., Wolchok, J., Mautino, M., Celis, E., Sharpe, A., Francisco, L., Powell, J., Yagita, H., Mellor, A. L., Blazar, B. & Munn, D. H., 2015, In : Journal for ImmunoTherapy of Cancer. 3, O19.

Research output: Contribution to journalArticle

Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner

Holmgaard, R. B., Zamarin, D., Li, Y., Gasmi, B., Munn, D. H., Allison, J. P., Merghoub, T. & Wolchok, J. D., Oct 13 2015, In : Cell Reports. 13, 2, p. 412-424 13 p.

Research output: Contribution to journalArticle

186 Scopus citations

β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin a metabolism in dendritic cells

Hong, Y., Manoharan, I., Suryawanshi, A., Majumdar, T., Angus-Hill, M. L., Koni, P. A., Manicassamy, B., Mellor, A. L., Munn, D. H. & Manicassamy, S., Feb 15 2015, In : Cancer Research. 75, 4, p. 656-665 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
2014

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., Lee, J. R., Offermanns, S. & Ganapathy, V., Jan 16 2014, In : Immunity. 40, 1, p. 128-139 12 p.

Research output: Contribution to journalArticle

724 Scopus citations

Activation of the STING adaptor attenuates experimental autoimmune encephalitis

Lemos, H., Huang, L., Chandler, P. R., Mohamed, E., Souza, G. R., Li, L., Pacholczyk, G., Barber, G. N., Hayakawa, Y., Munn, D. H. & Mellor, A. L., Jun 15 2014, In : Journal of Immunology. 192, 12, p. 5571-5578 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Epitope-optimized alpha-fetoprotein genetic vaccines prevent carcinogen-induced murine autochthonous hepatocellular carcinoma

Hong, Y., Peng, Y., Guo, Z. S., Guevara-Patino, J., Pang, J., Butterfield, L. H., Mivechi, N. F., Munn, D. H., Bartlett, D. L. & He, Y., Apr 2014, In : Hepatology. 59, 4, p. 1448-1458 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology

Liu, H., Huang, L., Bradley, J., Liu, K., Bardhan, K., Ron, D., Mellor, A. L., Munn, D. H. & McGaha, T. L., Feb 2014, In : Molecular and Cellular Biology. 34, 3, p. 428-438 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Highlights and summary of the 28th annual meeting of the Society for Immunotherapy of Cancer

Ascierto, P. A., Munn, D. H., Palucka, A. K. & Sondel, P. M., May 15 2014, In : Journal for ImmunoTherapy of Cancer. 2, 1, 15.

Research output: Contribution to journalReview article

1 Scopus citations

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

Dubovsky, J. A., Flynn, R., Du, J., Harrington, B. K., Zhong, Y., Kaffenberger, B., Yang, C., Towns, W. H., Lehman, A., Johnson, A. J., Muthusamy, N., Devine, S. M., Jaglowski, S., Serody, J. S., Murphy, W. J., Munn, D. H., Luznik, L., Hill, G. R., Wong, H. K., MacDonald, K. K. P. & 10 others, Maillard, I., Koreth, J., Elias, L., Cutler, C., Soiffer, R. J., Antin, J. H., Ritz, J., Panoskaltsis-Mortari, A., Byrd, J. C. & Blazar, B. R., Nov 3 2014, In : Journal of Clinical Investigation. 124, 11, p. 4867-4876 10 p.

Research output: Contribution to journalArticle

92 Scopus citations

Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor cd4 t-cell responses through the PD-1-PD-L1 axis

Ding, Z. C., Lu, X., Yu, M., Lemos, H., Huang, L., Chandler, P., Liu, K., Walters, M., Krasinski, A., Mack, M., Blazar, B. R., Mellor, A. L., Munn, D. H. & Zhou, G., Jul 1 2014, In : Cancer Research. 74, 13, p. 3441-3453 13 p.

Research output: Contribution to journalArticle

73 Scopus citations

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

Flynn, R., Du, J., Veenstra, R. G., Reichenbach, D. K., Panoskaltsis-Mortari, A., Taylor, P. A., Freeman, G. J., Serody, J. S., Murphy, W. J., Munn, D. H., Sarantopoulos, S., Luznik, L., Maillard, I., Koreth, J., Cutler, C., Soiffer, R. J., Antin, J. H., Ritz, J., Dubovsky, J. A., Byrd, J. C. & 3 others, MacDonald, K. P., Hill, G. R. & Blazar, B. R., Jun 19 2014, In : Blood. 123, 25, p. 3988-3998 11 p.

Research output: Contribution to journalArticle

104 Scopus citations

Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance

Ravishankar, B., Shinde, R., Liu, H., Chaudhary, K., Bradley, J., Lemos, H. P., Phillip, C., Tanaka, M., Munn, D. H., Mellor, A. L. & McGaha, T. L., Mar 18 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 11, p. 4215-4220 6 p.

Research output: Contribution to journalArticle

64 Scopus citations