Find Research Outputs — Augusta University Research Profiles

2019

3-Amino-chromanes and Tetrahydroquinolines as Selective 5-HT_2B, 5-HT₇, or σ₁ Receptor Ligands

Porter, M. R., Xiao, H., Wang, J., Smith, S. B. & Topczewski, J. J., Oct 10 2019, In : ACS Medicinal Chemistry Letters. 10, 10, p. 1436-1442 7 p.

Research output: Contribution to journal › Article

G-Protein-Coupled Receptors

Ligands

Oxidative stress

Neurotransmitter Agents

Assays

Activation of sigma 1 receptor extends survival of cones and improves visual acuity in a murine model of retinitis pigmentosa

Wang, J., Saul, A. & Smith, S. B., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 13, p. 4397-4407 11 p.

Research output: Contribution to journal › Article

Open Access

Retinitis Pigmentosa

Visual Acuity

Pentazocine

Retinal Cone Photoreceptor Cells

Optical Coherence Tomography

3 Citations (Scopus)

Excess homocysteine upregulates the NRF2-antioxidant pathway in retinal Müller glial cells

Navneet, S., Cui, X., Zhao, J., Wang, J., Kaidery, N. A., Thomas, B., Bollinger, K. E., Yoon, Y. & Smith, S. B., Jan 2019, In : Experimental eye research. 178, p. 228-237 10 p.

Research output: Contribution to journal › Article

Homocysteine

Neuroglia

Up-Regulation

Antioxidants

Oxidative Stress

3 Citations (Scopus)

Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2

Navneet, S., Zhao, J., Wang, J., Mysona, B. A., Barwick, S., Ammal Kaidery, N., Saul, A. B., Kaddour-Djebbar, I., Bollag, W. B., Thomas, B., Bollinger, K. E. & Smith, S. B., Jun 1 2019, In : Redox Biology. 24, 101199.

Research output: Contribution to journal › Article

Open Access

Hyperhomocysteinemia

Retinal Ganglion Cells

Neuroglia

Antioxidants

Excitatory Amino Acids

4 Citations (Scopus)

The molecular chaperone sigma 1 receptor mediates rescue of retinal cone photoreceptor cells via modulation of NRF2

Wang, J., Zhao, J., Cui, X., Mysona, B. A., Navneet, S., Saul, A., Ahuja, M., Lambert, N., Gazaryan, I. G., Thomas, B., Bollinger, K. E. & Smith, S. B., Apr 2019, In : Free Radical Biology and Medicine. 134, p. 604-616 13 p.

Research output: Contribution to journal › Article

Retinal Cone Photoreceptor Cells

Molecular Chaperones

Cones

Modulation

Antioxidant Response Elements

2018

3 Citations (Scopus)

Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses

Fouda, A. Y., Xu, Z., Shosha, E., Lemtalsi, T., Chen, J., Toque, H. A., Tritz, R., Cui, X., Stansfield, B. K., Huo, Y., Rodriguez, P. C., Smith, S. B., Caldwell, R. W., Narayanan, S. P. & Caldwell, R. B., Oct 1 2018, In : Cell Death and Disease. 9, 10, 1001.

Research output: Contribution to journal › Article

Arginase

Ischemia

Macrophages

Reperfusion Injury

Knockout Mice

1 Citation (Scopus)

Depletion of the receptor-interacting protein kinase 3 (RIP3) decreases photoreceptor cell death during the early stages of ocular murine cytomegalovirus infection

Xu, J., Mo, J., Liu, X., Marshall, B., Atherton, S. S., Dong, Z., Smith, S. & Zhang, M., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2445-2458 14 p.

Research output: Contribution to journal › Article

Receptor-Interacting Protein Serine-Threonine Kinases

Muromegalovirus

Photoreceptor Cells

Cytomegalovirus Infections

Protein Kinases

7 Citations (Scopus)

Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression

Chaudhary, K., Promsote, W., Ananth, S., Veeranan-Karmegam, R., Tawfik, A. M., Arjunan, P., Martin, P. M., Smith, S. B., Thangaraju, M., Kisselev, O., Ganapathy, V. & Gnana-Prakasam, J. P., Dec 1 2018, In : Scientific Reports. 8, 1, 3025.

Research output: Contribution to journal › Article

Iron Overload

Diabetic Retinopathy

Renin

Iron

Knockout Mice

3 Citations (Scopus)

Relationship between Sigma-1 receptor and BDNF in the visual system

Mysona, B. A., Zhao, J., Smith, S. & Bollinger, K. E., Feb 2018, In : Experimental eye research. 167, p. 25-30 6 p.

Research output: Contribution to journal › Article

Brain-Derived Neurotrophic Factor

Optic Disk

Astrocytes

Retina

Retinal Ganglion Cells

11 Citations (Scopus)

Sigma 1 receptor: A novel therapeutic target in retinal disease

Smith, S. B., Wang, J., Cui, X., Mysona, B. A., Zhao, J. & Bollinger, K. E., Nov 2018, In : Progress in Retinal and Eye Research. 67, p. 130-149 20 p.

Research output: Contribution to journal › Review article

Retinal Diseases

Therapeutics

Retina

sigma-1 receptor

Photoreceptor Cells

2017

9 Citations (Scopus)

Absence of sigma 1 receptor accelerates photoreceptor cell death in a murine model of retinitis pigmentosa

Wang, J., Saul, A., Cui, X., Roon, P. & Smith, S. B., Sep 2017, In : Investigative Ophthalmology and Visual Science. 58, 11, p. 4545-4558 14 p.

Research output: Contribution to journal › Article

Photoreceptor Cells

Retinitis Pigmentosa

Cell Death

Endoplasmic Reticulum Stress

Gliosis

5 Citations (Scopus)

Analysis of MTHFR, CBS, glutathione, taurine, and hydrogen sulfide levels in retinas of hyperhomocysteinemic mice

Cui, X., Navneet, S., Wang, J., Roon, P., Chen, W., Xian, M. & Smith, S. B., Apr 2017, In : Investigative Ophthalmology and Visual Science. 58, 4, p. 1954-1963 10 p.

Research output: Contribution to journal › Article

Glutathione Synthase

Cystathionine

Methylenetetrahydrofolate Reductase (NADPH2)

Hydrogen Sulfide

Taurine

3 Citations (Scopus)

Detailed electroretinographic findings in rd8 mice

Saul, A. B., Cui, X., Markand, S. & Smith, S. B., Jun 1 2017, In : Documenta Ophthalmologica. 134, 3, p. 195-203 9 p.

Research output: Contribution to journal › Article

Retina

Phenotype

Amacrine Cells

Light

Retinal Degeneration

9 Citations (Scopus)

Hyperhomocysteinemia alters retinal endothelial cells barrier function and angiogenic potential via activation of oxidative stress

Mohamed, R., Sharma, I., Ibrahim, A. S., Saleh, H., Elsherbiny, N. M., Fulzele, S., Elmasry, K., Smith, S. B., Al-Shabrawey, M. & Tawfik, A., Dec 1 2017, In : Scientific reports. 7, 1, 09731.

Research output: Contribution to journal › Article

Hyperhomocysteinemia

Oxidative Stress

Endothelial Cells

Homocysteine

Blood-Retinal Barrier

5 Citations (Scopus)

Introduction to sigma receptors: Their role in disease and as therapeutic targets

Smith, S. B., Jan 1 2017, In : Advances in experimental medicine and biology. 964, p. 1-4 4 p.

Research output: Contribution to journal › Article

sigma Receptors

Neurodegenerative diseases

Molecular imaging

Retinal Degeneration

Somatoform Disorders

7 Citations (Scopus)

p38MAPK plays a critical role in induction of a pro-inflammatory phenotype of retinal Müller cells following Zika virus infection

Zhu, S., Luo, H., Liu, H., Ha, Y., Mays, E. R., Lawrence, R. E., Winkelmann, E., Barrett, A. D., Smith, S. B., Wang, M., Wang, T. & Zhang, W., Sep 2017, In : Antiviral Research. 145, p. 70-81 12 p.

Research output: Contribution to journal › Article

Phenotype

Intercellular Signaling Peptides and Proteins

Posterior Uveitis

Eye Abnormalities

Pathology

12 Citations (Scopus)

Protective effects of agonists of growth hormone-releasing hormone (GHRH) in early experimental diabetic retinopathy

Thounaojam, M. C., Powell, F. L., Patel, S., Gutsaeva, D. R., Tawfik, A., Smith, S. B., Nussbaum, J., Block, N. L., Martin, P. M., Schally, A. V. & Bartoli, M., Dec 12 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 50, p. 13248-13253 6 p.

Research output: Contribution to journal › Article

Growth Hormone-Releasing Hormone

Diabetic Retinopathy

Retina

Streptozocin

Hormone Antagonists

6 Citations (Scopus)

Sigma 1 receptor regulates ERK activation and promotes survival of optic nerve head astrocytes

Zhao, J., Mysona, B. A., Wang, J., Gonsalvez, G. B., Smith, S. B. & Bollinger, K. E., Sep 2017, In : PloS one. 12, 9, e0184421.

Research output: Contribution to journal › Article

astrocytes

Optic Disk

optics

Astrocytes

Optics

2 Citations (Scopus)

The role of sigma1R in mammalian retina

Wang, J., Cui, X., Roon, P., Saul, A. & Smith, S. B., Jan 1 2017, In : Advances in experimental medicine and biology. 964, p. 267-284 18 p.

Research output: Contribution to journal › Article

Retina

Ganglia

sigma-1 receptor

Cells

Photoreceptor Cells

35 Citations (Scopus)

The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure

Lee, H., Smith, S. B. & Yoon, Y., Apr 28 2017, In : Journal of Biological Chemistry. 292, 17, p. 7115-7130 16 p.

Research output: Contribution to journal › Article

Autosomal Dominant Optic Atrophy

Dynamins

Optics

Mitochondrial Dynamics

Fusion reactions

2016

14 Citations (Scopus)

(+)-pentazocine reduces NMDA-induced murine retinal ganglion cell death through a σr1-dependent mechanism

Zhao, J., Mysona, B. A., Qureshi, A., Kim, L., Fields, T., Gonsalvez, G. B., Smith, S. B. & Bollinger, K. E., Feb 2016, In : Investigative Ophthalmology and Visual Science. 57, 2, p. 453-461 9 p.

Research output: Contribution to journal › Article

Pentazocine

Retinal Ganglion Cells

N-Methylaspartate

Cell Death

Knockout Mice

31 Citations (Scopus)

Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration

Wang, J., Saul, A., Roon, P. & Smith, S. B., Jun 28 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. E3764-E3772

Research output: Contribution to journal › Article

Retinal Degeneration

Molecular Chaperones

Retinal Diseases

Photoreceptor Cells

Retinal Cone Photoreceptor Cells

10 Citations (Scopus)

Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration

Ibrahim, A. S., Mander, S., Hussein, K. A., Elsherbiny, N. M., Smith, S. B., Al-Shabrawey, M. & Tawfik, A., Jan 1 2016, In : Oncotarget. 7, 8, p. 8532-8545 14 p.

Research output: Contribution to journal › Article

Hyperhomocysteinemia

Retinal Pigments

Macular Degeneration

Homocysteine

Choroidal Neovascularization

5 Citations (Scopus)

Mthfr as a modifier of the retinal phenotype of Crb1^rd8/rd8 mice

Markand, S., Saul, A. B., Tawfik, A. M., Cui, X., Rozen, R. & Smith, S. B., Apr 1 2016, In : Experimental eye research. 145, p. 164-172 9 p.

Research output: Contribution to journal › Article

Retinal Degeneration

Phenotype

Methylenetetrahydrofolate Reductase (NADPH2)

Mutation

Blood Vessels

4 Citations (Scopus)

Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease

Promsote, W., Powell, F. L., Veean, S., Thounaojam, M., Markand, S., Saul, A., Gutsaeva, D., Bartoli, M., Smith, S. B., Ganapathy, V. & Martin, P. M., Dec 10 2016, In : Antioxidants and Redox Signaling. 25, 17, p. 921-935 15 p.

Research output: Contribution to journal › Article

Fumarates

Sickle Cell Anemia

Oxidative stress

Pathology

Oxidative Stress

3 Citations (Scopus)

Progesterone Receptor Membrane Component 1 (PGRMC1) Expression in Murine Retina

Shanmugam, A. K., Mysona, B. A., Wang, J., Zhao, J., Tawfik, A., Sanders, A., Markand, S., Zorrilla, E., Ganapathy, V., Bollinger, K. E. & Smith, S. B., Aug 2 2016, In : Current Eye Research. 41, 8, p. 1105-1112 8 p.

Research output: Contribution to journal › Article

Progesterone Receptors

Retina

Membranes

Gene Expression

Intestines

4 Citations (Scopus)

Role of sigma 1 receptor in retinal degeneration of the Ins2^Akita/+ murine model of diabetic retinopathy

Wang, J., Cui, X., Roon, P. & Smith, S. B., May 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 6, p. 2770-2781 12 p.

Research output: Contribution to journal › Article

Retinal Degeneration

Diabetic Retinopathy

Pentazocine

Gliosis

Ganglia

2015

22 Citations (Scopus)

A lipidomic screen of hyperglycemia-treated hrecs links 12/15-lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase

Ibrahim, A. S., Elshafey, S., Sellak, H., Hussein, K. A., El-Sherbiny, M., Abdelsaid, M., Rizk, N., Beasley, S., Tawfik, A. M., Smith, S. B. & Al-Shabrawey, M., Mar 1 2015, In : Journal of Lipid Research. 56, 3, p. 599-611 13 p.

Research output: Contribution to journal › Article

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid

NADPH Oxidase

Arachidonate 15-Lipoxygenase

Diabetic Retinopathy

Hyperglycemia

26 Citations (Scopus)

Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma

Ha, Y., Liu, H., Xu, Z., Yokota, H., Narayanan, S. P., Lemtalsi, T., Smith, S. B., Caldwell, R. W., Caldwell, R. B. & Zhang, W., Oct 1 2015, In : Cell Death and Disease. 6, 10, e1900.

Research output: Contribution to journal › Article

Endoplasmic Reticulum Stress

Glaucoma

Intraocular Pressure

Inflammation

Wounds and Injuries

57 Citations (Scopus)

Hyperglycemia, p53, and mitochondrial pathway of apoptosis are involved in The susceptibility of diabetic models to ischemic acute kidney injury

Peng, J., Li, X., Zhang, D., Chen, J. K., Su, Y., Smith, S. B. & Dong, Z., Jan 3 2015, In : Kidney International. 87, 1, p. 137-150 14 p.

Research output: Contribution to journal › Article

Acute Kidney Injury

Hyperglycemia

Apoptosis

Kidney

Glucose

20 Citations (Scopus)

Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids

Ibrahim, A. S., Tawfik, A. M., Hussein, K. A., Elshafey, S., Markand, S., Rizk, N., Duh, E. J., Smith, S. B. & Al-Shabrawey, M., Mar 2015, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1851, 3, p. 290-298 9 p.

Research output: Contribution to journal › Article

Eicosanoids

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid

NADPH Oxidase

Hydroxyeicosatetraenoic Acids

Diabetic Retinopathy

16 Citations (Scopus)

Retinal ganglion cell loss and mild vasculopathy in methylene tetrahydrofolate reductase (Mthfr)-deficient mice: A model of mild hyperhomocysteinemia

Markand, S., Saul, A., Roon, P., Prasad, P., Martin, P., Rozen, R., Ganapathy, V. & Smith, S. B., Jan 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 4, p. 2684-2695 12 p.

Research output: Contribution to journal › Article

Methylenetetrahydrofolate Reductase (NADPH2)

Hyperhomocysteinemia

Retinal Ganglion Cells

Immunohistochemistry

Electroretinography

52 Citations (Scopus)

Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system x_c^-, the Na⁺-independent glutamate-cystine exchanger

Wang, J., Shanmugam, A., Markand, S., Zorrilla, E., Ganapathy, V. & Smith, S. B., Jun 14 2015, In : Free Radical Biology and Medicine. 86, p. 25-36 12 p., 12387.

Research output: Contribution to journal › Article

Oxidative stress

Cystine

Neuroglia

Glutamic Acid

Oxidative Stress

9 Citations (Scopus)

Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1γ, MIP2, MIP3α, and IL12 (p40/p70) by retinal Müller glial cells

Shanmugam, A., Wang, J., Markand, S., Perry, R. L., Tawfik, A., Zorrilla, E., Ganapathy, V. & Smith, S. B., Mar 1 2015, In : Journal of Neurochemistry. 132, 5, p. 546-558 13 p.

Research output: Contribution to journal › Article

Interleukin-12

Neuroglia

Lipopolysaccharides

Chemical activation

Cytokines

2014

14 Citations (Scopus)

Alterations of retinal vasculature in cystathionine-β-synthase heterozygous mice: A model of mild to moderate hyperhomocysteinemia

Tawfik, A., Markand, S., Al-Shabrawey, M., Mayo, J. N., Reynolds, J., Bearden, S. E., Ganapathy, V. & Smith, S. B., Sep 2014, In : American Journal of Pathology. 184, 9, p. 2573-2585 13 p.

Research output: Contribution to journal › Article

Cystathionine

Hyperhomocysteinemia

Zonula Occludens-1 Protein

Occludin

Blood Vessels

8 Citations (Scopus)

Deletion of hemojuvelin, an iron-regulatory protein, in mice results in abnormal angiogenesis and vasculogenesis in retina along with reactive gliosis

Tawfik, A., Gnana-Prakasam, J. P., Smith, S. B. & Ganapathy, V., May 8 2014, In : Investigative Ophthalmology and Visual Science. 55, 6, p. 3616-3625 10 p.

Research output: Contribution to journal › Article

Iron-Regulatory Proteins

Gliosis

Retina

Blood Vessels

Microglia

15 Citations (Scopus)

Dysregulation of system x_c^- expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 mice

Frederick, N. M., Bertho, J., Patel, K. K., Petr, G. T., Bakradze, E., Smith, S. B. & Rosenberg, P. A., Oct 2014, In : Neurochemistry International. 76, p. 59-69 11 p.

Research output: Contribution to journal › Article

Corpus Striatum

Huntington Disease

Oxidative Stress

Cell Line

Proteins

Folate Transport in Retina and Consequences on Retinal Structure and Function of Hyperhomocysteinemia

Smith, S. B., Ganapathy, P. S., Bozard, R. B. & Ganapathy, V., Apr 10 2014, Handbook of Nutrition, Diet and the Eye. Elsevier Inc., p. 349-359 11 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Hyperhomocysteinemia

Folic Acid

Retina

Proton-Coupled Folate Transporter

Reduced Folate Carrier Protein

7 Citations (Scopus)

Interplay of autophagy and apoptosis during murine cytomegalovirus infection of RPE cells

Mo, J., Zhang, M., Marshall, B., Smith, S., Covar, J. & Atherton, S., Aug 14 2014, In : Molecular Vision. 20, p. 1161-1173 13 p.

Research output: Contribution to journal › Article

Muromegalovirus

Retinal Pigments

Autophagy

Cytomegalovirus Infections

Epithelial Cells

19 Citations (Scopus)

Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina.

Promsote, W., Makala, L., Li, B., Smith, S. B., Singh, N., Ganapathy, V., Pace, B. S. & Martin, P. M., Aug 2014, In : Investigative ophthalmology & visual science. 55, 8, p. 5382-5393 12 p.

Research output: Contribution to journal › Article

Fetal Hemoglobin

Erythroid Cells

Retinal Pigments

Globins

Retina

21 Citations (Scopus)

Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid

Ananth, S., Gnana-Prakasam, J. P., Bhutia, Y. D., Veeranan-Karmegam, R., Martin, P. M., Smith, S. B. & Ganapathy, V., Apr 1 2014, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1842, 4, p. 603-612 10 p.

Research output: Contribution to journal › Article

Siderophores

Hemochromatosis

Retina

Cholesterol

Iron

4 Citations (Scopus)

Retinal expression of the serine protease matriptase-2 (tmprss6) and its role in retinal iron homeostasis

Gnana-Prakasam, J. P., Baldowski, R. B., Ananth, S., Martin, P. M., Smith, S. B. & Ganapathy, V., Apr 26 2014, In : Molecular Vision. 20, p. 561-574 14 p.

Research output: Contribution to journal › Article

Serine Proteases

Retina

Homeostasis

Iron

Hepcidins

4 Citations (Scopus)

Role of bax in death of uninfected retinal cells during murine cytomegalovirus retinitis

Mo, J., Marshall, B., Covar, J., Zhang, N. Y., Smith, S. B., Atherton, S. S. & Zhang, M., Sep 23 2014, In : Investigative Ophthalmology and Visual Science. 55, 11, p. 7137-7146 10 p.

Research output: Contribution to journal › Article

Cytomegalovirus Retinitis

Muromegalovirus

Receptor-Interacting Protein Serine-Threonine Kinases

Caspases

Caspase 3

30 Citations (Scopus)

Sigma receptor 1 modulates ER stress and Bcl2 in murine retina

Ha, Y., Shanmugam, A. K., Markand, S., Zorrilla, E., Ganapathy, V. & Smith, S. B., Apr 2014, In : Cell and Tissue Research. 356, 1, p. 15-27 13 p.

Research output: Contribution to journal › Article

Endoplasmic Reticulum Stress

Retina

Transcriptome

Proto-Oncogene Proteins c-bcl-2

Cell Death

31 Citations (Scopus)

Sigma receptor ligand, (+)-pentazocine, suppresses inflammatory responses of retinal microglia

Zhao, J., Ha, Y., Liou, G. I., Gonsalvez, G. B., Smith, S. B. & Bollinger, K. E., May 8 2014, In : Investigative Ophthalmology and Visual Science. 55, 6, p. 3375-3384 10 p.

Research output: Contribution to journal › Article

sigma Receptors

Pentazocine

Microglia

Ligands

Lipopolysaccharides

2013

13 Citations (Scopus)

Alterations of retinal vasculature in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia

Tawfik, A., Al-Shabrawey, M., Roon, P., Sonne, S., Covar, J. A., Matragoon, S., Ganapathy, P. S., Atherton, S. S., El-Remessy, A., Ganapathy, V. & Smith, S. B., Feb 1 2013, In : Investigative Ophthalmology and Visual Science. 54, 2, p. 939-949 11 p.

Research output: Contribution to journal › Article

Cystathionine beta-Synthase

Hyperhomocysteinemia

Homocysteine

Tight Junctions

Blood-Retinal Barrier

11 Citations (Scopus)

Cystathionine beta synthase expression in mouse retina

Markand, S., Tawfik, A. M., Ha, Y., Gnana-Prakasam, J. P., Sonne, S., Ganapathy, V., Sen, N., Xian, M. & Smith, S. B., May 1 2013, In : Current Eye Research. 38, 5, p. 597-604 8 p.

Research output: Contribution to journal › Article

Cystathionine beta-Synthase

Retina

Cystathionine

Liver

Enzyme Assays

27 Citations (Scopus)

Diabetes and Overexpression of proNGF Cause Retinal Neurodegeneration via Activation of RhoA Pathway

Al-Gayyar, M. M. H., Mysona, B. A., Matragoon, S., Abdelsaid, M. A., El-Azab, M. F., Shanab, A. Y., Ha, Y., Smith, S. B., Bollinger, K. E. & El-Remessy, A. B., Jan 30 2013, In : PloS one. 8, 1, e54692.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Medical problems

diabetes

Chemical activation

Cells

Erratum: GADD34 induces cell death through inactivation of Akt following traumatic brain injury (Cell Death and Disease (2013) 4 (e754) DOI: 10.1038/cddis.2013.280)

Farook, J. M., Shields, J., Tawfik, A., Markand, S., Sen, T., Smith, S. B., Brann, D., Dhandapani, K. M. & Sen, N., Sep 1 2013, In : Cell Death and Disease. 4, 9, e813.

Research output: Contribution to journal › Comment/debate

42 Citations (Scopus)

GADD34 induces cell death through inactivation of Akt following traumatic brain injury

Farook, J. M., Shields, J., Tawfik, A., Markand, S., Sen, T., Smith, S. B., Brann, D., Dhandapani, K. M. & Sen, N., Aug 2013, In : Cell Death and Disease. 4, 8, e754.

Research output: Contribution to journal › Article

TNF Receptor-Associated Factor 6

Cell Death

Activating Transcription Factor 4

Phosphorylation

Ubiquitin-Protein Ligases