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2020

Better survival is observed in cervical cancer patients positive for specific anti-glycan antibodies and receiving brachytherapy

Purohit, S., Ferris, D. G., Alvarez, M., Tran, P. M. H., Tran, L. K. H., Mysona, D. P., Hopkins, D., Zhi, W., Dun, B., Wallbillich, J. J., Cummings, R. D., Wang, P. G. & She, J. X., Jan 1 2020, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Brachytherapy
Uterine Cervical Neoplasms
Polysaccharides
Anti-Idiotypic Antibodies
Survival

Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers

Mysona, D. P., Tran, L. K. H., Tran, P. M. H., Gehrig, P. A., Van Le, L., Ghamande, S., Rungruang, B. J., Java, J., Mann, A. K., Liao, J., Kapp, D. S., Santos, B. D., She, J. X. & Chan, J. K., Jan 2020, In : Gynecologic Oncology. 156, 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

Drug Therapy
Neoplasms
Survival
Lymph Node Excision
Cell Biology
2019
2 Citations (Scopus)

A combined score of clinical factors and serum proteins can predict time to recurrence in high grade serous ovarian cancer

Mysona, D., Pyrzak, A., Purohit, S., Zhi, W., Sharma, A., Tran, L., Tran, P., Bai, S., Rungruang, B., Ghamande, S. & She, J. X., Mar 2019, In : Gynecologic Oncology. 152, 3, p. 574-580 7 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Blood Proteins
Recurrence
Disease-Free Survival
Proteins
2 Citations (Scopus)

A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential

Gobin, E., Bagwell, K., Wagner, J., Mysona, D., Sandirasegarane, S., Smith, N., Bai, S., Sharma, A., Schleifer, R. & She, J. X., Jun 14 2019, In : BMC Cancer. 19, 1, 581.

Research output: Contribution to journalArticle

Open Access
Metalloproteases
Transcriptome
Matrix Metalloproteinases
Neoplasms
Genes
4 Citations (Scopus)

Association of gluten intake during the first 5 years of life with incidence of celiac disease autoimmunity and celiac disease among children at increased risk

Andrén Aronsson, C., Lee, H. S., Hård Af Segerstad, E. M., Uusitalo, U., Yang, J., Koletzko, S., Liu, E., Kurppa, K., Bingley, P. J., Toppari, J., Ziegler, A. G., She, J. X., Hagopian, W. A., Rewers, M., Akolkar, B., Krischer, J. P., Virtanen, S. M., Norris, J. M. & Agardh, D., Aug 13 2019, In : JAMA - Journal of the American Medical Association. 322, 6, p. 514-523 10 p.

Research output: Contribution to journalArticle

Glutens
Celiac Disease
Autoimmunity
Incidence
Autoantibodies

Cell-based high throughput screening identified a novel compound that promotes regulatory T cells and prevents autoimmune colitis

Mao, R., Liu, H., Yi, B., Purohit, S., Kuczma, M., Kraj, P. & She, J. X., Nov 2019, In : Biochemical Pharmacology. 169, 113618.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
Colitis
Screening
Throughput
1 Citation (Scopus)

Early probiotic supplementation and the risk of celiac disease in children at genetic risk

TEDDY study group, Aug 2019, In : Nutrients. 11, 8, 1790.

Research output: Contribution to journalArticle

Open Access
celiac disease
Probiotics
Celiac Disease
probiotics
autoimmunity
2 Citations (Scopus)

Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families

The TEDDY study group, Apr 1 2019, In : Diabetes. 68, 4, p. 847-857 11 p.

Research output: Contribution to journalArticle

Open Access
Type 1 Diabetes Mellitus
Population
Genetic Predisposition to Disease
Autoimmunity
Autoantibodies
5 Citations (Scopus)

Identification of novel T1D risk loci and their association with age and islet function at diagnosis in autoantibody-positive T1D individuals: Based on a two-stage genome-wide association study

Zhu, M., Xu, K., Chen, Y., Gu, Y., Zhang, M., Luo, F., Liu, Y., Gu, W., Hu, J., Xu, H., Xie, Z., Sun, C., Li, Y., Sun, M., Xu, X., Hsu, H. T., Chen, H., Fu, Q., Shi, Y., Xu, J. & 33 others, Ji, L., Liu, J., Bian, L., Zhu, J., Chen, S., Xiao, L., Li, X., Jiang, H., Shen, M., Huang, Q., Fang, C., Li, X., Huang, G., Fan, J., Jiang, Z., Jiang, Y., Dai, J., Ma, H., Zheng, S., Cai, Y., Dai, H., Zheng, X., Zhou, H., Ni, S., Jin, G., She, J. X., Yu, L., Polychronakos, C., Hu, Z., Zhou, Z., Weng, J., Shen, H. & Yang, T., Aug 1 2019, In : Diabetes Care. 42, 8, p. 1414-1421 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Type 1 Diabetes Mellitus
Autoantibodies
Odds Ratio
C-Peptide
5 Citations (Scopus)

Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study

The TEDDY study group, Feb 1 2019, In : Pediatric Diabetes. 20, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

Dietary Supplements
Autoimmunity
Mothers
Autoantibodies
Vitamin D

Metabolite-related dietary patterns and the development of islet autoimmunity

The TEDDY study group, Dec 1 2019, In : Scientific reports. 9, 1, 14819.

Research output: Contribution to journalArticle

Open Access
Autoimmunity
Phospholipid Ethers
Metabolomics
Sphingomyelins
Phosphatidylcholines
8 Citations (Scopus)

Predicting islet cell autoimmunity and type 1 diabetes: An 8-year teddy study progress report

TEDDY study group, Jun 1 2019, In : Diabetes Care. 42, 6, p. 1051-1060 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Islets of Langerhans
Autoantibodies
ROC Curve
3 Citations (Scopus)

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

The TEDDY study group, May 2019, In : Pediatric Diabetes. 20, 3, p. 263-270 8 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Logistic Models
Insulinoma
Area Under Curve
1 Citation (Scopus)

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study

Beyerlein, A., Bonifacio, E., Vehik, K., Hippich, M., Winkler, C., Frohnert, B. I., Steck, A. K., Hagopian, W. A., Krischer, J. P., Lernmark, Å., Rewers, M. J., She, J. X., Toppari, J., Akolkar, B., Rich, S. S. & Ziegler, A. G., Sep 1 2019, In : Journal of medical genetics. 56, 9, p. 602-605 4 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
HLA Antigens
Genotype

The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children

TEDDY study group, Sep 18 2019, In : BMC pediatrics. 19, 1, 339.

Research output: Contribution to journalArticle

Open Access
Breast Feeding
Respiratory Tract Infections
Otitis Media
Gastroenteritis
Tracheitis
7 Citations (Scopus)

Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children

for the TEDDY Study Group*, Jan 1 2019, In : Diabetes. 68, 1, p. 119-130 12 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Insulinoma
HLA-DR3 Antigen
Insulin
2018
11 Citations (Scopus)

Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study

for the TEDDY Study Group, Mar 1 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

Celiac Disease
Cesarean Section
Autoimmunity
Confidence Intervals
Nonparametric Statistics
1 Citation (Scopus)
Autoimmunity
Type 1 Diabetes Mellitus
Respiratory Tract Infections
Single Nucleotide Polymorphism
Emotions
2 Citations (Scopus)

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journalArticle

Keratin-8
keratins
Keratin
Cytoskeletal Proteins
cancer
6 Citations (Scopus)

Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

Tailor, P. D., Kodeboyina, S. K., Bai, S., Sharma, S., Ratnani, A., Copland, J. A., She, J-X., Sharma, A. K. & Patel, N., Apr 1 2018, In : Oncotarget. 9, 25, p. 17876-17888 13 p.

Research output: Contribution to journalArticle

Kallikreins
Renal Cell Carcinoma
Biomarkers
Genes
Neoplasms
15 Citations (Scopus)

Early infant diet and islet autoimmunity in the TEDDY study

Uusitalo, U., Lee, H. S., Aronsson, C. A., Vehik, K., Yang, J., Hummel, S., Silvis, K., Lernmark, Å., Rewers, M., Hagopian, W., She, J. X., Simell, O., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J., Virtanen, S. M. & Norris, J. M., Mar 1 2018, In : Diabetes Care. 41, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

Autoimmunity
Diet
Glutens
Type 1 Diabetes Mellitus
Insulin Antibodies
24 Citations (Scopus)

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children

for the TEDDY Study Group, Apr 2018, In : PLoS Medicine. 15, 4, e1002548.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Prospective Studies
Genotype
Primary Prevention
1 Citation (Scopus)

Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - A preliminary report

Shiao, S. P. K., Xiao, H., Dong, L., Wang, X., Liu, K., She, J. & Shi, H., May 22 2018, In : Oncotarget. 9, 39, p. 25557-25571 15 p.

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Colorectal Neoplasms
Genome
Neoplasm Genes
7 Citations (Scopus)

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies

on behalf of & TEDDY study group, Jan 2018, In : Journal of Autoimmunity. 86, p. 93-103 11 p.

Research output: Contribution to journalArticle

HLA Antigens
Respiratory Tract Infections
Autoantibodies
Type 1 Diabetes Mellitus
Infection
10 Citations (Scopus)

Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort

TEDDY study group, May 2018, In : Journal of Autoimmunity. 89, p. 90-100 11 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Genes
Single Nucleotide Polymorphism
Cohort Studies
3 Citations (Scopus)

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J. X., Belin de Chantemele, E. J. & Csányi, G., Sep 2018, In : British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

Research output: Contribution to journalArticle

Imipramine
United States Food and Drug Administration
Pharmaceutical Preparations
Endocytosis
Electron Scanning Microscopy
1 Citation (Scopus)

KLHL5 knockdown increases cellular sensitivity to anticancer drugs

Schleifer, R. J., Li, S., Nechtman, W., Miller, E., Bai, S., Sharma, A. K. & She, J-X., Dec 1 2018, In : Oncotarget. 9, 100, p. 37429-37438 10 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Neoplasms
Cell Cycle
Aurora Kinases
Cullin Proteins
17 Citations (Scopus)

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Purohit, S. B., Li, T., Guan, W., Song, X., Song, J., Tian, Y., Li, L., Sharma, A. K., Dun, B., Mysona, D., Ghamande, S. A., Rungruang, B. J., Cummings, R. D., Wang, P. G. & She, J-X., Dec 1 2018, In : Nature Communications. 9, 1, 258.

Research output: Contribution to journalArticle

antibodies
beads
Polysaccharides
Carrier Proteins
Throughput
2 Citations (Scopus)

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

for the TEDDY Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Vaccination
Autoantibodies
Finland
23 Citations (Scopus)

Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Lernmark, Å., Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J-X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., Jan 1 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Vitamin D
25-Hydroxyvitamin D3 1-alpha-Hydroxylase
Odds Ratio
1 Citation (Scopus)

Proteins of TNF-α and IL6 pathways are elevated in serum of type-1 diabetes patients with microalbuminuria

Purohit, S. B., Sharma, A. K., Zhi, W., Bai, S., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D. & She, J-X., Jan 31 2018, In : Frontiers in immunology. 9, JAN, 154.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Interleukin-6
Serum
Proteins
Cytokine Receptor gp130

Proteomic approach to identify biomarkers for invasive cervix cancer - a prospective pilot study

Mysona, D., Pyrzak, A., Allen, J., Powell, M., Kleven, D., Zhi, W., Sharma, A., Bai, S., She, J. X., Rungruang, B. & Ghamande, S., Jan 1 2018, In : European Journal of Gynaecological Oncology. 39, 5, p. 737-742 6 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Proteomics
Biomarkers
Prospective Studies
Serum
100 Citations (Scopus)

Temporal development of the gut microbiome in early childhood from the TEDDY study

Stewart, C. J., Ajami, N. J., O’Brien, J. L., Hutchinson, D. S., Smith, D. P., Wong, M. C., Ross, M. C., Lloyd, R. E., Doddapaneni, H. V., Metcalf, G. A., Muzny, D., Gibbs, R. A., Vatanen, T., Huttenhower, C., Xavier, R. J., Rewers, M., Hagopian, W., Toppari, J., Ziegler, A. G., She, J-X. & 6 others, Akolkar, B., Lernmark, A., Hyoty, H., Vehik, K., Krischer, J. P. & Petrosino, J. F., Oct 25 2018, In : Nature. 562, 7728, p. 583-588 6 p.

Research output: Contribution to journalLetter

Microbiota
Bacteroides
Human Milk
Autoimmunity
Type 1 Diabetes Mellitus
7 Citations (Scopus)

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

The TEDDY study group, Dec 1 2018, In : Current Diabetes Reports. 18, 12, 136.

Research output: Contribution to journalReview article

Type 1 Diabetes Mellitus
Autoimmunity
HLA-DQ Antigens
Gene-Environment Interaction
Micronutrients
73 Citations (Scopus)

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

Vatanen, T., Franzosa, E. A., Schwager, R., Tripathi, S., Arthur, T. D., Vehik, K., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Stewart, C. J., Ajami, N. J., Petrosino, J. F., Gevers, D., Lähdesmäki, H., Vlamakis, H. & 2 others, Huttenhower, C. & Xavier, R. J., Oct 25 2018, In : Nature. 562, 7728, p. 589-594 6 p.

Research output: Contribution to journalLetter

Microbiota
Type 1 Diabetes Mellitus
Autoimmunity
Metagenome
Volatile Fatty Acids
2017
6 Citations (Scopus)

Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity

for the TEDDY Study Group, May 16 2017, In : BMC pediatrics. 17, 1, 127.

Research output: Contribution to journalArticle

Antipyretics
Autoimmunity
Analgesics
Acetaminophen
Anti-Inflammatory Agents
17 Citations (Scopus)

Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity

Kemppainen, K. M., Vehik, K., Lynch, K. F., Larsson, H. E., Canepa, R. J., Simell, V., Koletzko, S., Liu, E., Simell, O. G., Toppari, J., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W. A., She, J-X., Akolkar, B., Schatz, D. A., Atkinson, M. A., Blaser, M. J., Krischer, J. P. & 185 others, Hyöty, H., Agardh, D., Triplett, E. W., Bautista, K., Baxter, J., Bedoy, R., Felipe-Morales, D., Driscoll, K., Frohnert, B. I., Gesualdo, P., Hoffman, M., Karban, R., Norris, J., Samper-Imaz, A., Steck, A., Waugh, K., Wright, H., Adamsson, A., Ahonen, S., Ilonen, J., Jokipuu, S., Kallio, T., Karlsson, L., Kähönen, M., Knip, M., Kovanen, L., Koreasalo, M., Kurppa, K., Latva-Aho, T., Lönnrot, M., Mäntymäki, E., Multasuo, K., Mykkänen, J., Niininen, T., Niinistö, S., Nyblom, M., Rajala, P., Rautanen, J., Riikonen, A., Riikonen, M., Rouhiainen, J., Romo, M., Simell, T., Sjöberg, M., Stenius, A., Leppänen, M., Vainionpää, S., Varjonen, E., Veijola, R., Virtanen, S. M., Vähä-Mäkilä, M., Åkerlund, M., Lindfors, K., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Adams, J., Silvis, K., Haller, M., Gardiner, M., McIndoe, R. A., Sharma, A. K., William, J., Young, G., Anderson, S. W., Jacobsen, L., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Janz, N., Kersting, M., Knopff, A., Peplow, C., Roth, R., Scholz, M., Stock, J., Warncke, K., Wendel, L., Winkler, C., Aronsson, C. A., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallström, E., Fransson, L., Gard, T., Gerardsson, J., Bennet, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonsdottir, B., Lindström, M., Lundgren, M., Månsson-Martinez, M., Markan, M., Melin, J., Mestan, Z., Ottosson, K., Rahmati, K., Ramelius, A., Salami, F., Sibthorpe, S., Sjöberg, B., Swartling, U., Amboh, E. T., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Killian, M., Crouch, C. C., Skidmore, J., Carson, J., Dalzell, M., Dunson, K., Hervey, R., Johnson, C., Lyons, R., Meyer, A., Mulenga, D., Tarr, A., Uland, M., Willis, J., Becker, D., Franciscus, M., Smith, M. E. D. E., Daftary, A., Klein, M. B., Yates, C., Abbondondolo, M., Austin-Gonzalez, S., Avendano, M., Baethke, S., Brown, R., Burkhardt, B., Butterworth, M., Clasen, J., Cuthbertson, D., Eberhard, C., Fiske, S., Garcia, D., Garmeson, J., Gowda, V., Heyman, K., Laras, F. P., Lee, H. S., Liu, S., Liu, X., Lynch, K., Malloy, J., McCarthy, C., Meulemans, S., Parikh, H., Shaffer, C., Smith, L., Smith, S., Sulman, N., Tamura, R., Uusitalo, U., Vijayakandipan, P., Wood, K., Yang, J., Ballard, L., Hadley, D., McLeod, W., Bourcier, K., Briese, T., Johnson, S. B., Yu, L., Miao, D., Bingley, P., William's, A., Chandler, K., Rokni, S., Willia, C., Wyatt, R., George, G., Grace, S. & Mulholland, N., Dec 2017, In : JAMA Pediatrics. 171, 12, p. 1217-1225 9 p.

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Type 1 Diabetes Mellitus
Anti-Bacterial Agents
Autoantibodies
4 Citations (Scopus)

Blood-based biomarkers for precision medicine in lung cancer: Precision radiation therapy

De Ruysscher, D., Jin, J., Lautenschlaeger, T., She, J. X., Liao, Z. & Kong, F. M. S., Dec 1 2017, In : Translational Lung Cancer Research. 6, 6, p. 661-669 9 p.

Research output: Contribution to journalReview article

Precision Medicine
Lung Neoplasms
Radiotherapy
Biomarkers
Organs at Risk
16 Citations (Scopus)

Co-occurrence of type 1 diabetes and celiac disease autoimmunity

Hagopian, W., Lee, H. S., Liu, E., Rewers, M., She, J. X., Ziegler, A. G., Lernmark, A., Toppari, J., Rich, S. S., Krischer, J. P., Erlich, H., Akolkar, B. & Agardh, D., Nov 2017, In : Pediatrics. 140, 5, e20171305.

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
Genetic Loci
41 Citations (Scopus)

Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life

TEDDY study group, May 2017, In : Clinical Gastroenterology and Hepatology. 15, 5, p. 694-702.e5

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Glutens
Infection
Rotavirus
15 Citations (Scopus)

First infant formula type and risk of islet autoimmunity in the environmental determinants of diabetes in the young (TEDDY) study

Hummel, S., Beyerlein, A., Tamura, R., Uusitalo, U., Andŕen Aronsson, C., Yang, J., Riikonen, A., Lernmark, A., Rewers, M. J., Hagopian, W. A., She, J. X., Simell, O. G., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Virtanen, S. M. & Norris, J. M., Mar 1 2017, In : Diabetes Care. 40, 3, p. 398-404 7 p.

Research output: Contribution to journalArticle

Infant Formula
Autoimmunity
Type 1 Diabetes Mellitus
Survival Analysis
Breast Feeding
40 Citations (Scopus)

Genetic and environmental interactions modify the risk of diabetes-related autoimmunity by 6 years of age: The teddy study

Krischer, J. P., Lynch, K. F., Lernmark, A., Hagopian, W. A., Rewers, M. J., She, J. X., Toppari, J., Ziegler, A. G. & Akolkar, B., Sep 1 2017, In : Diabetes Care. 40, 9, p. 1194-1202 9 p.

Research output: Contribution to journalArticle

Autoimmunity
Autoantibodies
Single Nucleotide Polymorphism
Antibodies
Environmental Exposure
7 Citations (Scopus)

Identification of serum proteins and multivariate models for diagnosis and therapeutic monitoring of lung cancer

Ma, R., Xu, H., Wu, J., Sharma, A. K., Bai, S., Dun, B., Jing, C., Cao, H., Wang, Z., She, J-X. & Feng, J., Jan 1 2017, In : Oncotarget. 8, 12, p. 18901-18913 13 p.

Research output: Contribution to journalArticle

Blood Proteins
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Proteins
Area Under Curve
8 Citations (Scopus)

Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study

Ancillary Studies, Diet, Genetics, Human Subjects/Publicity/Publications, Immune Markers, Infectious Agents, Laboratory Implementation, Maternal Studies, Psychosocial, Quality Assurance, Steering, Study Coordinators, Celiac Disease, Clinical Implementation & TEDDY study group, Nov 1 2017, In : Acta Diabetologica. 54, 11, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Joints
Bayes Theorem
Statistical Models
6 Citations (Scopus)

Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study

Yang, J., Tamura, R. N., Aronsson, C. A., Uusitalo, U. M., Lernmark, Å., Rewers, M., Hagopian, W. A., She, J. X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Agardh, D., Feb 14 2017, In : British Journal of Nutrition. 117, 3, p. 466-472 7 p.

Research output: Contribution to journalArticle

Celiac Disease
Dietary Supplements
Mothers
Pregnancy
Autoimmunity
16 Citations (Scopus)

Psychological manifestations of celiac disease autoimmunity in young children

The TEDDY study group, Mar 2017, In : Pediatrics. 139, 3, e20162848.

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Psychology
Mothers
Autoantibodies
24 Citations (Scopus)

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

On behalf of the TEDDY Study Group, Oct 1 2017, In : Diabetologia. 60, 10, p. 1931-1940 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Respiratory Tract Infections
Autoantibodies
Tracheitis
37 Citations (Scopus)

The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history on the progression from multiple autoantibodies to type 1 diabetes: A teddy study report

Krischer, J. P., Liu, X., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J. X., Toppari, J., Ziegler, A. G. & Akolkar, B., Dec 1 2017, In : Diabetes. 66, 12, p. 3122-3129 8 p.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Type 1 Diabetes Mellitus
Autoantibodies
HLA-DQ Antigens
HLA-DR Antigens
2016
6 Citations (Scopus)
Regression Analysis
Pediatrics
Logistic Models
Population
Health
90 Citations (Scopus)

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study

Dietary Biomarkers Laboratory, Project Scientist, Other contributors, Autoantibody Reference Laboratories, Cortisol Laboratory, Data Coordinating Center, Pennsylvania Satellite Center, Washington Clinical Center, Sweden Clinical Center, Finland Clinical Center, Germany Clinical Center, Georgia/Florida Clinical Center, for the TEDDY Study Group, SNP Laboratory, RNA Laboratory and Gene Expression Laboratory, Microbiome and Viral Metagenomics Laboratory, Metabolomics Laboratory, HbA1c Laboratory, HLA Reference Laboratory, OGTT Laboratory & 2 others, Proteomics Laboratory & Repository, Jan 2016, In : JAMA Pediatrics. 170, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

Probiotics
Autoimmunity
Type 1 Diabetes Mellitus
Genotype
Autoantibodies