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2019
1 Citation (Scopus)

Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity

Zong, X., Dong, Y., Li, Y., Yang, L., Li, Y., Yang, B., Tucker, L., Zhao, N., Brann, D. W., Yan, X., Hu, S. & Zhang, Q., Jan 1 2019, (Accepted/In press) In : Translational Stroke Research.

Research output: Contribution to journalArticle

Transcranial Magnetic Stimulation
Stroke
Wounds and Injuries
Cytokines
Phenotype
2 Citations (Scopus)

Expression of aromatase and synthesis of sex steroid hormones in skeletal muscle following exercise training in ovariectomized rats

Shi, R., Tian, X., Feng, Y., Cheng, Z., Lu, J., Brann, D. W. & Zhang, Q., Mar 1 2019, In : Steroids. 143, p. 91-96 6 p.

Research output: Contribution to journalArticle

Aromatase
Gonadal Steroid Hormones
Muscle
Rats
Skeletal Muscle
7 Citations (Scopus)

Neuron-derived estrogen regulates synaptic plasticity and memory

Lu, Y., Sareddy, G. R., Wang, J., Wang, R., Li, Y., Dong, Y., Zhang, Q., Liu, J., O’Connor, J. C., Xu, J., Vadlamudi, R. K. & Brann, D. W., Apr 10 2019, In : Journal of Neuroscience. 39, 15, p. 2792-2809 18 p.

Research output: Contribution to journalArticle

Open Access
Neuronal Plasticity
Aromatase
Prosencephalon
Estrogens
Neurons
5 Citations (Scopus)

Photobiomodulation for Global Cerebral Ischemia: Targeting Mitochondrial Dynamics and Functions

Wang, R., Dong, Y., Lu, Y., Zhang, W., Brann, D. W. & Zhang, Q., Mar 1 2019, In : Molecular Neurobiology. 56, 3, p. 1852-1869 18 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Brain Ischemia
Apoptosomes
Mitochondrial Degradation
Therapeutics
2018
5 Citations (Scopus)

17β-estradiol regulates microglia activation and polarization in the hippocampus following global cerebral ischemia

Thakkar, R., Wang, R., Wang, J., Vadlamudi, R. K. & Brann, D. W., Jan 1 2018, In : Oxidative medicine and cellular longevity. 2018, 4248526.

Research output: Contribution to journalArticle

Microglia
Brain Ischemia
Estradiol
Hippocampus
Chemical activation
6 Citations (Scopus)

Deletion of NADPH oxidase 4 reduces severity of traumatic brain injury

Ma, M. W., Wang, J., Dhandapani, K. M. & Brann, D. W., Mar 1 2018, In : Free Radical Biology and Medicine. 117, p. 66-75 10 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Brain
Oxidative stress
Oxidative Stress
Cerebral Cortex

Influence of the interaction between Ac-SDKP and ang II on the pathogenesis and development of silicotic fibrosis

Zhang, Y., Yang, F., Liu, Y., Peng, H. B., Geng, Y. C., Li, S. F., Xu, H., Zhu, L. Y., Yang, X. H. & Brann, D. W., Jun 2018, In : Molecular Medicine Reports. 17, 6, p. 7467-7476 10 p.

Research output: Contribution to journalArticle

Angiotensin II
Fibrosis
Valsartan
Peptidyl-Dipeptidase A
Silicosis
2 Citations (Scopus)

NADPH oxidase 2 deletion enhances neurogenesis following traumatic brain injury

Wang, J., Ma, M. W., Dhandapani, K. M. & Brann, D. W., Aug 1 2018, In : Free Radical Biology and Medicine. 123, p. 62-71 10 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Neurogenesis
Brain
Reactive Oxygen Species
Stem Cells
16 Citations (Scopus)

NADPH oxidases in traumatic brain injury – Promising therapeutic targets?

Ma, M. W., Wang, J., Dhandapani, K. M., Wang, R. & Brann, D. W., Jun 2018, In : Redox Biology. 16, p. 285-293 9 p.

Research output: Contribution to journalShort survey

NADPH Oxidase
Brain
Oxidative stress
Oxidative Stress
Therapeutics
5 Citations (Scopus)

PELP1: a key mediator of oestrogen signalling and actions in the brain

Thakkar, R., Sareddy, G. R., Zhang, Q., Wang, R., Vadlamudi, R. K. & Brann, D. W., Feb 1 2018, In : Journal of Neuroendocrinology. 30, 2, e12484.

Research output: Contribution to journalReview article

Estrogens
Brain
Proteins
human PELP1 protein
Chromatin Assembly and Disassembly
2 Citations (Scopus)

Swimming improves cognitive reserve in ovariectomized rats and enhances neuroprotection after global cerebral ischemia

Zhang, M., Zhai, Y., Sun, Y., Zhang, W., Li, Q., Brann, D. W. & Wang, R., Aug 1 2018, In : Brain Research. 1692, p. 110-117 8 p.

Research output: Contribution to journalArticle

Cognitive Reserve
Brain Ischemia
Brain-Derived Neurotrophic Factor
Interleukin-4
Cognition
2017
14 Citations (Scopus)

Activation of myeloid TLR4 Mediates T lymphocyte polarization after traumatic brain injury

Braun, M., Vaibhav, K., Saad, N., Fatima, S., Brann, D. W., Vender, J. R., Wang, L. P., Hoda, M. N., Baban, B. & Dhandapani, K. M., May 1 2017, In : Journal of Immunology. 198, 9, p. 3615-3626 12 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Macrophages
Monocytes
Adaptive Immunity
Brain
20 Citations (Scopus)

Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis

Liu, Y., Xu, H., Geng, Y., Xu, D., Zhang, L., Yang, Y., Wei, Z., Zhang, B., Li, S., Gao, X., Wang, R., Zhang, X., Brann, D. W. & Yang, F., Feb 21 2017, In : Respiratory Research. 18, 1, 38.

Research output: Contribution to journalArticle

CREB-Binding Protein
Silicosis
Myofibroblasts
Pulmonary Fibrosis
Cyclic AMP-Dependent Protein Kinases
26 Citations (Scopus)
Inflammasomes
NADPH Oxidase
Brain
Chemical activation
Oxidative stress
96 Citations (Scopus)

NADPH oxidase in brain injury and neurodegenerative disorders

Ma, M. W., Wang, J., Zhang, Q., Wang, R., Dhandapani, K. M., Vadlamudi, R. K. & Brann, D. W., Jan 17 2017, In : Molecular Neurodegeneration. 12, 1, 7.

Research output: Contribution to journalReview article

NADPH Oxidase
Brain Diseases
Neurodegenerative Diseases
Brain Injuries
Pathology
18 Citations (Scopus)

Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia

Zhu, Y., Zhang, Q., Zhang, W., Li, N., Dai, Y., Tu, J., Yang, F., Brann, D. W. & Wang, R., Feb 16 2017, In : Scientific Reports. 7, 42660.

Research output: Contribution to journalArticle

Vascular Dementia
Common Carotid Artery
Cognition
Estradiol
Spine
16 Citations (Scopus)
Macrophages
NADPH Oxidase
Microglia
Brain
Polarization
26 Citations (Scopus)

Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease

Lu, Y., Dong, Y., Tucker, D., Wang, R., Ahmed, M. E., Brann, D. W. & Zhang, Q., Jan 1 2017, In : Journal of Alzheimer's Disease. 56, 4, p. 1469-1484 16 p.

Research output: Contribution to journalArticle

Streptozocin
Alzheimer Disease
Oxidative Stress
Hippocampus
Anti-Inflammatory Agents
2016
8 Citations (Scopus)

Acetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica

Xiaojun, W., Yan, L., Hong, X., Xianghong, Z., Shifeng, L., Dingjie, X., Xuemin, G., Lijuan, Z., Bonan, Z., Zhongqiu, W., Ruimin, W., Brann, D. & Fang, Y., Aug 31 2016, In : Scientific reports. 6, 32257.

Research output: Contribution to journalArticle

Tubulin
Silicon Dioxide
Fibrosis
Silicosis
Lung
8 Citations (Scopus)

Neuroprotection Mediated through GluN2C-Containing N-methyl-D-aspartate (NMDA) Receptors Following Ischemia

Chung, C., Marson, J. D., Zhang, Q., Kim, J., Wu, W. H., Brann, D. W. & Chen, B. S., Nov 15 2016, In : Scientific Reports. 6, 37033.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Ischemia
Neurons
N-Methylaspartate
Brain Ischemia
27 Citations (Scopus)

NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation by 17 β -Estradiol

Thakkar, R., Wang, R., Sareddy, G., Wang, J., Thiruvaiyaru, D., Vadlamudi, R., Zhang, Q. & Brann, D., Jan 1 2016, In : Oxidative medicine and cellular longevity. 2016, 8309031.

Research output: Contribution to journalArticle

Inflammasomes
Brain Ischemia
Estradiol
Brain
Chemical activation
12 Citations (Scopus)

Protective effect of Ac-SDKP on alveolar epithelial cells through inhibition of EMT via TGF-β1/ROCK1 pathway in silicosis in rat

Deng, H., Xu, H., Zhang, X., Sun, Y., Wang, R., Brann, D. W. & Yang, F., Mar 1 2016, In : Toxicology and Applied Pharmacology. 294, p. 1-10 10 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Silicosis
Epithelial-Mesenchymal Transition
Rats
Pulmonary Surfactant-Associated Protein A
2015
31 Citations (Scopus)

Cell-permeable peptide targeting the Nrf2-keap1 interaction: A potential novel therapy for global cerebral ischemia

Tu, J., Zhang, X., Zhu, Y., Dai, Y., Li, N., Yang, F., Zhang, Q., Brann, D. W. & Wang, R., Nov 4 2015, In : Journal of Neuroscience. 35, 44, p. 14727-14739 13 p.

Research output: Contribution to journalArticle

NF-E2-Related Factor 2
Trans-Activators
Brain Ischemia
Peptides
Therapeutics
21 Citations (Scopus)

Proline-, glutamic acid-, and leucine-rich protein 1 mediates estrogen rapid signaling and neuroprotection in the brain

Sareddy, G. R., Zhang, Q., Wang, R., Scott, E., Zou, Y., O'Connor, J. C., Chen, Y., Dong, Y., Vadlamudi, R. K. & Brann, D. W., Dec 1 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 48, p. E6673-E6682

Research output: Contribution to journalArticle

Estrogens
Brain
Glycogen Synthase Kinase 3
Prosencephalon
Brain Ischemia
18 Citations (Scopus)

Prosurvival NMDA 2A receptor signaling mediates postconditioning neuroprotection in the hippocampus

Zhang, X., Zhang, Q., Tu, J., Zhu, Y., Yang, F., Liu, B., Brann, D. W. & Wang, R., Mar 1 2015, In : Hippocampus. 25, 3, p. 286-296 11 p.

Research output: Contribution to journalArticle

Brain Ischemia
Hippocampus
Phosphorylation
N-Methyl-D-Aspartate Receptors
Ischemia
34 Citations (Scopus)
Selective Estrogen Receptor Modulators
Neurogenesis
Brain Ischemia
Rats
Spine
2014
3 Citations (Scopus)

Beneficial effects of estrogens in the brain and cardiovascular system

Brann, D. W. & Mahesh, V. B., May 25 2014, In : Molecular and Cellular Endocrinology. 389, 1-2, 1 p.

Research output: Contribution to journalEditorial

Women's Health
Cardiovascular System
Estrogen Receptors
Estrogens
Brain
55 Citations (Scopus)

Brain-derived estrogen exerts anti-inflammatory and neuroprotective actions in the rat hippocampus

Zhang, Q., Wang, R., Tang, H., Dong, Y., Chan, A., Sareddy, G. R., Vadlamudi, R. K. & Brann, D. W., May 25 2014, In : Molecular and Cellular Endocrinology. 389, 1-2, p. 84-91 8 p.

Research output: Contribution to journalArticle

Aromatase
Brain Ischemia
Rats
Hippocampus
Brain
49 Citations (Scopus)

GPR30 mediates estrogen rapid signaling and neuroprotection

Tang, H., Zhang, Q., Yang, L., Dong, Y., Khan, M. B., Yang, F., Brann, D. W. & Wang, R., Apr 25 2014, In : Molecular and Cellular Endocrinology. 387, 1-2, p. 52-58 7 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
GTP-Binding Proteins
Estrogen Receptors
Estrogens
Brain Ischemia
10 Citations (Scopus)

Low dose Hsp90 inhibitor 17AAG protects neural progenitor cells from ischemia induced death

Bradley, E., Zhao, X., Wang, R., Brann, D. W., Bieberich, E. & Wang, G., Dec 30 2014, In : Journal of Cell Communication and Signaling. 8, 4, p. 353-362 10 p.

Research output: Contribution to journalArticle

tanespimycin
Cell death
Stem Cells
Ischemia
Cell Death
13 Citations (Scopus)

PELP1 oncogenic functions involve alternative splicing via PRMT6

Mann, M., Zou, Y., Chen, Y., Brann, D. & Vadlamudi, R., Mar 2014, In : Molecular Oncology. 8, 2, p. 389-400 12 p.

Research output: Contribution to journalArticle

Alternative Splicing
Estrogen Receptors
Breast Neoplasms
human PELP1 protein
Genes
16 Citations (Scopus)

Premature menopause and risk of neurological disease: Basic mechanisms and clinical implications

Scott, E. L., Zhang, Q., Vadlamudi, R. K. & Brann, D. W., May 25 2014, In : Molecular and Cellular Endocrinology. 389, 1-2, p. 2-6 5 p.

Research output: Contribution to journalReview article

Premature Menopause
Nervous System Diseases
Brain Ischemia
Observational Studies
Dementia
24 Citations (Scopus)

Proline, glutamic acid and leucine-rich protein-1 is essential for optimal p53-mediated DNA damage response

Nair, B. C., Krishnan, S. R., Sareddy, G. R., Mann, M., Xu, B., Natarajan, M., Hasty, P., Brann, D., Tekmal, R. R. & Vadlamudi, R. K., Sep 2014, In : Cell Death and Differentiation. 21, 9, p. 1409-1418 10 p.

Research output: Contribution to journalArticle

DNA Damage
Ataxia Telangiectasia
Camptothecin
p53 Genes
Etoposide
20 Citations (Scopus)

Reprint of "GPR30 mediates estrogen rapid signaling and neuroprotection"

Tang, H., Zhang, Q., Yang, L., Dong, Y., Khan, M. B., Yang, F., Brann, D. W. & Wang, R., May 25 2014, In : Molecular and Cellular Endocrinology. 389, 1-2, p. 92-98 7 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
GTP-Binding Proteins
Estrogen Receptors
Estrogens
Brain Ischemia
2 Citations (Scopus)

Surgical menopause enhances hippocampal amyloidogenesis following global cerebral ischemia

Scott, E. L., Zhang, Q., Dong, Y., Han, D., Wang, R. M., Vadlamudi, R. K. & Brann, D. W., Jan 1 2014, In : Journal of Sport and Health Science. 3, 3, p. 206-216 11 p.

Research output: Contribution to journalArticle

Menopause
Brain Ischemia
Ovariectomy
Nervous System Diseases
Dementia
2013
57 Citations (Scopus)

Early effects of high-fat diet on neurovascular function and focal ischemic brain injury

Li, W., Prakash, R., Chawla, D., Du, W., Didion, S. P., Filosa, J. A., Zhang, Q., Brann, D. W., Lima, V. V., Tostes, R. C. & Ergul, A., Jun 10 2013, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 11, p. R1001-R1008

Research output: Contribution to journalArticle

High Fat Diet
Brain Injuries
Basilar Artery
Middle Cerebral Artery Infarction
Stroke
39 Citations (Scopus)

Estrogen regulation of Dkk1 and Wnt/β-Catenin signaling in neurodegenerative disease

Scott, E. L. & Brann, D. W., Jun 13 2013, In : Brain Research. 1514, p. 63-74 12 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Neurodegenerative Diseases
Estrogens
Hormones
30 Citations (Scopus)

Estrogen regulation of spine density and excitatory synapses in rat prefrontal and somatosensory cerebral cortex

Khan, M. M., Dhandapani, K. M., Zhang, Q. & Brann, D. W., Jun 1 2013, In : Steroids. 78, 6, p. 614-623 10 p.

Research output: Contribution to journalArticle

Somatosensory Cortex
Cerebral Cortex
Synapses
Neurons
Rats
42 Citations (Scopus)

GADD34 induces cell death through inactivation of Akt following traumatic brain injury

Farook, J. M., Shields, J., Tawfik, A., Markand, S., Sen, T., Smith, S. B., Brann, D., Dhandapani, K. M. & Sen, N., Aug 2013, In : Cell Death and Disease. 4, 8, e754.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Cell Death
Activating Transcription Factor 4
Phosphorylation
Ubiquitin-Protein Ligases
64 Citations (Scopus)

Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS/Nrf2/HO-1 signaling

Wang, R., Tu, J., Zhang, Q., Zhang, X., Zhu, Y., Ma, W., Cheng, C., Brann, D. W. & Yang, F., Jul 1 2013, In : Hippocampus. 23, 7, p. 634-647 14 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Genistein
Brain Ischemia
Oxidative Stress
Neurons
30 Citations (Scopus)

Hypersensitivity of the hippocampal CA3 region to stress-induced neurodegeneration and amyloidogenesis in a rat model of surgical menopause

Zhang, Q., Wang, R. M., Scott, E., Han, D., Dong, Y., Tu, J. Y., Yang, F., Reddy Sareddy, G., Vadlamudi, R. K. & Brann, D. W., May 2013, In : Brain. 136, 5, p. 1432-1445 14 p.

Research output: Contribution to journalArticle

Hippocampal CA3 Region
Anatomic Models
Ovariectomy
Menopause
Hypersensitivity
28 Citations (Scopus)

KDM1 is a novel therapeutic target for the treatment of gliomas

Sareddy, G. R., Nair, B. C., Krishnan, S. K., Gonugunta, V. K., Zhang, Q. G., Suzuki, T., Miyata, N., Brenner, A. J., Brann, D. W. & Vadlamudi, R. K., 2013, In : Oncotarget. 4, 1, p. 18-28 11 p.

Research output: Contribution to journalArticle

Glioma
Heterografts
Therapeutics
p53 Genes
Epigenomics
15 Citations (Scopus)

Long-term estrogen deprivation leads to elevation of Dickkopf-1 and dysregulation of Wnt/β-Catenin signaling in hippocampal CA1 neurons

Scott, E. L., Zhang, Q., Han, D., Desai, B. N. & Brann, D. W., Jun 1 2013, In : Steroids. 78, 6, p. 624-632 9 p.

Research output: Contribution to journalArticle

Catenins
Brain Ischemia
Neurons
Rats
Estrogens
2012
40 Citations (Scopus)

A new antifibrotic target of Ac-SDKP: Inhibition of myofibroblast differentiation in rat lung with silicosis

Xu, H., Yang, F., Sun, Y., Yuan, Y., Cheng, H., Wei, Z., Li, S., Cheng, T., Brann, D. W. & Wang, R., Jul 3 2012, In : PloS one. 7, 7, e40301.

Research output: Contribution to journalArticle

Silicosis
Myofibroblasts
collagen
Rats
lungs
124 Citations (Scopus)

Critical role of nadph oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury

Zhang, Q., Laird, M. D., Han, D., Nguyen, K., Scott, E., Dong, Y., Dhandapani, K. M. & Brann, D. W., Apr 2 2012, In : PloS one. 7, 4, e34504.

Research output: Contribution to journalArticle

NADPH Oxidase
neuroglia
Microglia
Oxidative stress
Brain
83 Citations (Scopus)

Estrogen neuroprotection and the critical period hypothesis

Scott, E., Zhang, Q., Wang, R., Vadlamudi, R. & Brann, D. W., Jan 1 2012, In : Frontiers in Neuroendocrinology. 33, 1, p. 85-104 20 p.

Research output: Contribution to journalReview article

Estradiol
Estrogens
Menopause
Brain Ischemia
Neurodegenerative Diseases
36 Citations (Scopus)

Oestrogen signalling and neuroprotection in cerebral ischaemia

Brann, D. W., Raz, L., Wang, R., Vadlamudi, R. & Zhang, Q., Jan 1 2012, In : Journal of Neuroendocrinology. 24, 1, p. 34-47 14 p.

Research output: Contribution to journalReview article

Menopause
Brain Ischemia
Estrogens
Brain
Estrogen Replacement Therapy
53 Citations (Scopus)

Therapeutic significance of estrogen receptor β agonists in gliomas

Sareddy, G. R., Nair, B. C., Gonugunta, V. K., Zhang, Q. G., Brenner, A., Brann, D. W., Tekmal, R. R. & Vadlamudi, R. K., Jun 29 2012, In : Molecular cancer therapeutics. 11, 5, p. 1174-1182 9 p.

Research output: Contribution to journalArticle

Glioma
Estrogen Receptors
Estrogens
Neoplasms
Therapeutics
2011
25 Citations (Scopus)

Acetylation of the pro-apoptotic factor, p53 in the hippocampus following cerebral ischemia and modulation by estrogen

Raz, L., Zhang, Q., Han, D., Dong, Y., de Sevilla, L. & Brann, D. W., Nov 2 2011, In : PloS one. 6, 10, e27039.

Research output: Contribution to journalArticle

Acetylation
acetylation
hippocampus
ischemia
Brain Ischemia