Find Research Outputs

Search in all content

Filters for Scholarly Output

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Puttur D Prasad
2020

Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity

Suryawanshi, A., Hussein, M. S., Prasad, P. D. & Manicassamy, S., Feb 17 2020, In : Frontiers in immunology. 11, 122.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2019

Metabolic reprogramming by MYCN confers dependence on the serine-glycine-one-carbon biosynthetic pathway

Xia, Y., Ye, B., Ding, J., Yu, Y., Alptekin, A., Thangaraju, M., Prasad, P. D., Ding, Z. C., Park, E. J., Choi, J. H., Gao, B., Fiehn, O., Yan, C., Dong, Z., Zha, Y. & Ding, H. F., Aug 1 2019, In : Cancer Research. 79, 15, p. 3837-3850 14 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Vitamin B3: Niacin and transcriptome analysis in relation to the GPR109A receptor

Bridges, A., Rajpurohit, P., Prasad, P. D. & Thangaraju, M., Jan 1 2019, Molecular Nutrition: Vitamins. Elsevier, p. 673-690 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Canonical wnt signaling in CD11c + APCs regulates microbiota-Induced inflammation and immune cell homeostasis in the colon

Swafford, D., Shanmugam, A., Ranganathan, P., Hussein, M. S., Koni, P. A., Prasad, P. D., Thangaraju, M. & Manicassamy, S., May 1 2018, In : Journal of Immunology. 200, 9, p. 3259-3268 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

GPR81, a cell-surface receptor for lactate, regulates intestinal homeostasis and protects mice from experimental colitis

Ranganathan, P., Shanmugam, A. K., Swafford, D., Suryawanshi, A., Bhattacharjee, P., Hussein, M. S., Koni, P., Prasad, P. D., Kurago, Z. B., Thangaraju, M., Ganapathy, V. & Manicassamy, S., Mar 1 2018, In : Journal of Immunology. 200, 5, p. 1781-1789 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2017

The Relationship Between Probiotics and Dietary Fiber Consumption and Cardiovascular Health

Prasad, P. D., Gurav, A., Zhu, H., Martin, P. M., Vijay-Kumar, M. & Singh, N., Jul 13 2017, Dietary Fiber for the Prevention of Cardiovascular Disease: Fiber's Interaction between Gut Micoflora, Sugar Metabolism, Weight Control and Cardiovascular Health. Elsevier Inc., p. 73-90 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer

Coothankandaswamy, V., Cao, S., Xu, Y., Prasad, P. D., Singh, P. K., Reynolds, C. P., Yang, S., Ogura, J., Ganapathy, V. & Bhutia, Y. D., 2016, In : British Journal of Pharmacology. 173, 23, p. 3292-3306 15 p.

Research output: Contribution to journalArticle

35 Scopus citations

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis

Sivaprakasam, S., Prasad, P. D. & Singh, N., Aug 1 2016, In : Pharmacology and Therapeutics. 164, p. 144-151 8 p.

Research output: Contribution to journalReview article

86 Scopus citations

Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth

Pathania, R., Ramachandran, S., Mariappan, G., Thakur, P., Shi, H., Choi, J. H., Manicassamy, S., Kolhe, R., Prasad, P. D., Sharma, S., Lokeshwar, B. L., Ganapathy, V. & Thangaraju, M., Jun 1 2016, In : Cancer Research. 76, 11, p. 3224-3235 12 p.

Research output: Contribution to journalArticle

70 Scopus citations

Increased retinal expression of the pro-angiogenic receptor GPR91 via BMP6 in a mouse model of juvenile hemochromatosis

Arjunan, P., Gnanaprakasam, J. P., Ananth, S., Romej, M. A., Rajalakshmi, V. K., Prasad, P. D., Martin, P. M., Gurusamy, M., Thangaraju, M., Bhutia, Y. D. & Ganapathy, V., Apr 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 4, p. 1612-1619 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Deletion of the amino acid transporter SLC6A14 suppresses tumour growth in spontaneous mouse models of breast cancer

Babu, E., Bhutia, Y. D., Ramachandran, S., Gnana-Prakasam, J. P., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Jul 1 2015, In : Biochemical Journal. 469, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

Pathania, R., Ramachandran, S., Elangovan, S., Padia, R., Yang, P., Cinghu, S., Veeranan-Karmegam, R., Arjunan, P., Gnana-Prakasam, J. P., Sadanand, F., Pei, L., Chang, C. S., Choi, J. H., Shi, H., Manicassamy, S., Prasad, P. D., Sharma, S., Ganapathy, V., Jothi, R. & Thangaraju, M., Apr 22 2015, In : Nature communications. 6, 6910.

Research output: Contribution to journalArticle

117 Scopus citations
17 Scopus citations

Species-specific influence of lithium on the activity of SLC13A5 (NACT): Lithium-induced activation is specific for the transporter in primates

Gopal, E., Babu, E., Ramachandran, S., Bhutia, Y. D., Prasad, P. D. & Ganapathy, V., Apr 1 2015, In : Journal of Pharmacology and Experimental Therapeutics. 353, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., Lee, J. R., Offermanns, S. & Ganapathy, V., Jan 16 2014, In : Immunity. 40, 1, p. 128-139 12 p.

Research output: Contribution to journalArticle

711 Scopus citations

Butyrate-Mediated Protection Against Colonic Inflammation And Colon Carcinogenesis: Role Of Butyrate Transporters And Butyrate Receptors

Vadivel, G., Prasad, P. D., Thangaraju, M., Martin, P. M. & Singh, N., Apr 1 2014, Butyrate: Food Sources, Functions and Health Benefits. Nova Science Publishers, Inc., p. 157-176 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues

Blackburn, A. R., Hamrick, M. W., Chutkan, N., Sangani, R., Waller, J. L., Corpe, R., Prasad, P. D., Isales, C. M., Ganapathy, V. & Fulzele, S., Jan 8 2014, In : BMC Musculoskeletal Disorders. 15, 1, 9.

Research output: Contribution to journalArticle

1 Scopus citations

The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy

Bhutia, Y. D., Babu, E., Prasad, P. D. & Ganapathy, V., Dec 1 2014, In : Asian Journal of Pharmaceutical Sciences. 9, 6, p. 293-303 11 p.

Research output: Contribution to journalReview article

42 Scopus citations

The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival

Elangovan, S., Pathania, R., Ramachandran, S., Ananth, S., Padia, R. N., Lan, L., Singh, N., Martin, P. M., Hawthorn, L., Prasad, P. D., Ganapathy, V. & Thangaraju, M., Feb 15 2014, In : Cancer Research. 74, 4, p. 1166-1178 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
2013

Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth

Sonne, S. R., Bhalla, V. K., Barman, S. A., White, R. E., Zhu, S., Newman, T. M., Prasad, P. D., Smith, S. B., Offermanns, S. & Ganapathy, V., May 14 2013, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 8, p. 1149-1158 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Molecular mechanism of SLC5A8 inactivation in breast cancer

Elangovan, S., Pathania, R., Ramachandran, S., Ananth, S., Padia, R. N., Srinivas, S. R., Babu, E., Hawthorn, L., Schoenlein, P. V., Boettger, T., Smith, S. B., Prasad, P. D., Ganapathy, V. & Thangaraju, M., 2013, In : Molecular and Cellular Biology. 33, 19, p. 3920-3935 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

Sodium-coupled vitamin C transporter (SVCT2): Expression, function, and regulation in intervertebral disc cells

Chothe, P. P., Chutkan, N., Sangani, R., Wenger, K. H., Prasad, P. D., Thangaraju, M., Hamrick, M. W., Isales, C. M., Ganapathy, V. & Fulzele, S., May 1 2013, In : Spine Journal. 13, 5, p. 549-557 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Sodium-dependent vitamin C transporter SVCT2: Expression and function in bone marrow stromal cells and in osteogenesis

Fulzele, S., Chothe, P., Sangani, R., Chutkan, N., Hamrick, M., Bhattacharyya, M., Prasad, P. D., Zakhary, I., Bowser, M., Isales, C. & Ganapathy, V., Jan 2013, In : Stem Cell Research. 10, 1, p. 36-47 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function

Coothankandaswamy, V., Elangovan, S., Singh, N., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Feb 15 2013, In : Biochemical Journal. 450, 1, p. 169-178 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
116 Scopus citations
2012

Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate

Bozard, B. R., Chothe, P. P., Tawfik, A., Williams, C., Fulzele, S., Prasad, P. D., Martin, P. M., Ganapathy, V. & Smith, S. B., Mar 2012, In : Glia. 60, 3, p. 333-342 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2011

Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium

Gnana-Prakasam, J. P., Ananth, S., Prasad, P. D., Zhang, M., Atherton, S. S., Martin, P. M., Smith, S. B. & Ganapathy, V., May 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 3751-3758 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters

Rosario, F. J., Jansson, N., Kanai, Y., Prasad, P. D., Powell, T. L. & Jansson, T., Mar 2011, In : Endocrinology. 152, 3, p. 1119-1129 11 p.

Research output: Contribution to journalArticle

99 Scopus citations

Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate

Babu, E., Ramachandran, S., Coothankandaswamy, V., Elangovan, S., Prasad, P. D., Ganapathy, V. & Thangaraju, M., Sep 22 2011, In : Oncogene. 30, 38, p. 4026-4037 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

SIRT1 is essential for oncogenic signaling by estrogen/ estrogen receptor α in breast cancer

Elangovan, S., Ramachandran, S., Venkatesan, N., Ananth, S., Gnana-Prakasam, J. P., Martin, P. M., Browning, D. D., Schoenlein, P. V., Prasad, P. D., Ganapathy, V. & Thangaraju, M., Nov 1 2011, In : Cancer Research. 71, 21, p. 6654-6664 11 p.

Research output: Contribution to journalArticle

84 Scopus citations

SLC6A14 (ATB 0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer

Karunakaran, S., Ramachandran, S., Coothankandaswamy, V., Elangovan, S., Babu, E., Periyasamy-Thandavan, S., Gurav, A., Gnanaprakasam, J. P., Singh, N., Schoenlein, P. V., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Sep 9 2011, In : Journal of Biological Chemistry. 286, 36, p. 31830-31838 9 p.

Research output: Contribution to journalArticle

81 Scopus citations