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  • David C Hess
2020

A multicentre, randomised, sham-controlled trial on REmote iSchemic conditioning In patients with acute STroke (RESIST) – Rationale and study design

Blauenfeldt, R. A., Hjort, N., Gude, M. F., Behrndtz, A. B., Fisher, M., Valentin, J. B., Kirkegaard, H., Johnsen, S. P., Hess, D. C. & Andersen, G., Mar 1 2020, In : European Stroke Journal. 5, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA

Khodadadi, H., Salles, É. L., Jarrahi, A., Chibane, F., Costigliola, V., Yu, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M. & Baban, B., Sep 1 2020, In : Cannabis and Cannabinoid Research. 5, 3, p. 197-201 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

COVID-19-Related Stroke

Hess, D. C., Eldahshan, W. & Rutkowski, E., Jun 1 2020, In : Translational Stroke Research. 11, 3, p. 322-325 4 p.

Research output: Contribution to journalComment/debate

Open Access
41 Scopus citations

Establishment of an internationally agreed minimum data set for acute telestroke

Cadilhac, D. A., Bagot, K. L., Demaerschalk, B. M., Hubert, G., Schwamm, L., Watkins, C. L., Lightbody, C. E., Kim, J., Vu, M., Pompeani, N., Switzer, J., Caudill, J., Estrada, J., Viswanathan, A., Hubert, N., Ohannessian, R., Hargroves, D., Roberts, N., Ingall, T., Hess, D. C. & 3 others, Ranta, A., Padma, V. & Bladin, C. F., Jan 1 2020, (Accepted/In press) In : Journal of Telemedicine and Telecare.

Research output: Contribution to journalArticle

2 Scopus citations

Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury

Vaibhav, K., Braun, M., Alverson, K., Khodadadi, H., Kutiyanawalla, A., Ward, A., Banerjee, C., Sparks, T., Malik, A., Rashid, M. H., Rashid, M. H., Khan, M. B., Waters, M. F., Hess, D. C., Arbab, A. S., Vender, J. R., Hoda, N., Hoda, N., Hoda, N., Baban, B. & 3 others, Baban, B., Baban, B. & Dhandapani, K. M., May 2020, In : Science Advances. 6, 22, EAAX8847.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Short-Term Acute Exercise Preconditioning Reduces Neurovascular Injury After Stroke Through Induced eNOS Activation

Hafez, S., Khan, M. B., Awad, M. E., Wagner, J. D. & Hess, D. C., Aug 1 2020, In : Translational Stroke Research. 11, 4, p. 851-860 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Association Between Stroke Mortality and Time of Admission and Participation in a Telestroke Network

Witrick, B., Zhang, D., Switzer, J. A., Hess, D. C. & Shi, L., Feb 2020, In : Journal of Stroke and Cerebrovascular Diseases. 29, 2, 104480.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Impact of Participation in a Telestroke Network on Clinical Outcomes

Zhang, D., Shi, L., Ido, M. S., Green, D. E., Li, Y., Su, D. & Hess, D. C., Jan 1 2019, In : Circulation. Cardiovascular quality and outcomes. 12, 1, p. e005147

Research output: Contribution to journalArticle

5 Scopus citations
2018

Chronic Remote Ischemic Conditioning Is Cerebroprotective and Induces Vascular Remodeling in a VCID Model

Khan, M. B., Hafez, S., Hoda, M. N., Baban, B., Wagner, J., Awad, M. E., Sangabathula, H., Haigh, S., Elsalanty, M., Waller, J. L. & Hess, D. C., Feb 1 2018, In : Translational Stroke Research. 9, 1, p. 51-63 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Expansion of telestroke services improves quality of care provided in super rural areas

Zhang, D., Wang, G., Zhu, W., Thapa, J. R., Switzer, J. A., Hess, D. C., Smith, M. L. & Ritchey, M. D., Dec 2018, In : Health Affairs. 37, 12, p. 2005-2013 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Human neural stem cell extracellular vesicles improve recovery in a porcine model of ischemic stroke

Webb, R. L., Kaiser, E. E., Jurgielewicz, B. J., Spellicy, S., Scoville, S. L., Thompson, T. A., Swetenburg, R. L., Hess, D. C., West, F. D. & Stice, S. L., 2018, In : Stroke. 49, 5, p. 1248-1256 9 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model

Webb, R. L., Kaiser, E. E., Scoville, S. L., Thompson, T. A., Fatima, S., Pandya, C., Sriram, K., Swetenburg, R. L., Vaibhav, K., Arbab, A. S., Baban, B., Dhandapani, K. M., Hess, D. C., Hoda, M. N. & Stice, S. L., Oct 1 2018, In : Translational Stroke Research. 9, 5, p. 530-539 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation

Vaibhav, K., Braun, M., Khan, M. B., Fatima, S., Saad, N., Shankar, A., Khan, Z. T., Harris, R. B. S., Yang, Q., Huo, Y., Arbab, A. S., Giri, S., Alleyne, C. H., Vender, J. R., Hess, D. C., Baban, B., Hoda, M. N. & Dhandapani, K. M., Oct 1 2018, In : The Journal of experimental medicine. 215, 10, p. 2636-2654 19 p.

Research output: Contribution to journalArticle

13 Scopus citations

Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization

Braun, M., Khan, Z. T., Khan, M. B., Kumar, M., Ward, A., Achyut, B. R., Arbab, A. S., Hess, D. C., Hoda, M. N., Baban, B., Dhandapani, K. M. & Vaibhav, K., Feb 2018, In : Brain, Behavior, and Immunity. 68, p. 224-237 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Stem Cell Therapy in Cerebrovascular Disease

Nahhas, M. I. & Hess, D. C., Nov 1 2018, In : Current Treatment Options in Neurology. 20, 11, 49.

Research output: Contribution to journalReview article

2 Scopus citations
2017

Collaterals 2016: Translating the collaterome around the globe

for the Collaterals 2016 Consortium, 2017, In : International Journal of Stroke. 12, 4, p. 338-342 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Induced Pluripotent Stem Cell-Derived Neural Stem Cell Therapy Enhances Recovery in an Ischemic Stroke Pig Model

Baker, E. W., Platt, S. R., Lau, V. W., Grace, H. E., Holmes, S. P., Wang, L., Duberstein, K. J., Howerth, E. W., Kinder, H. A., Stice, S. L., Hess, D. C., Mao, H. & West, F. D., Dec 1 2017, In : Scientific reports. 7, 1, 10075.

Research output: Contribution to journalArticle

33 Scopus citations

Minocycline in acute cerebral hemorrhage an early phase randomized trial

Fouda, A. Y., Newsome, A. S., Spellicy, S., Waller, J. L., Zhi, W., Hess, D. C., Ergul, A., Edwards, D. J., Fagan, S. C. & Switzer, J. A., Oct 2017, In : Stroke. 48, 10, p. 2885-2887 3 p.

Research output: Contribution to journalArticle

19 Scopus citations

Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial

Hess, D. C., Wechsler, L. R., Clark, W. M., Savitz, S. I., Ford, G. A., Chiu, D., Yavagal, D. R., Uchino, K., Liebeskind, D. S., Auchus, A. P., Sen, S., Sila, C. A., Vest, J. D. & Mays, R. W., May 2017, In : The Lancet Neurology. 16, 5, p. 360-368 9 p.

Research output: Contribution to journalArticle

106 Scopus citations

Telemedicine quality and outcomes in stroke: A scientific statement for healthcare professionals from the American Heart Association/American Stroke Association

Wechsler, L. R., Demaerschalk, B. M., Schwamm, L. H., Adeoye, O. M., Audebert, H. J., Fanale, C. V., Hess, D. C., Majersik, J. J., Nystrom, K. V., Reeves, M. J., Rosamond, W. D. & Switzer, J. A., Jan 1 2017, In : Stroke. 48, 1, p. e3-e25

Research output: Contribution to journalArticle

91 Scopus citations

Cell Therapy for Brain Injury

Hess, D. C., Jan 1 2015, Springer International Publishing. 369 p.

Research output: Book/ReportBook

2 Scopus citations

Induced pluripotent stem cells as a cell-based therapeutic in stroke

Hess, D. C., Fakhri, N. & West, F. D., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 129-146 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Introduction to cell therapy in brain injury

Hess, D. C., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 1-9 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Preconditioning and cell-based therapeutics

Hess, D. C. & Hoda, MD. N., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 173-186 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Remote ischaemic conditioning-a new paradigm of self-protection in the brain

Hess, D. C., Blauenfeldt, R. A., Andersen, G., Hougaard, K. D., Hoda, M. N., Ding, Y. & Ji, X., Dec 1 2015, In : Nature Reviews Neurology. 11, 12, p. 698-710 13 p.

Research output: Contribution to journalReview article

60 Scopus citations

Telestroke: Variations in intravenous thrombolysis by spoke hospitals

Switzer, J. A., Singh, R., Mathiassen, L., Waller, J. L., Adams, R. J. & Hess, D. C., Jan 1 2015, In : Journal of Stroke and Cerebrovascular Diseases. 24, 4, p. 739-744 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014
16 Scopus citations

A double-blind placebo-controlled clinical evaluation of MultiStem for the treatment of ischemic stroke

Hess, D. C., Sila, C. A., Furlan, A. J., Wechsler, L. R., Switzer, J. A. & Mays, R. W., Apr 2014, In : International Journal of Stroke. 9, 3, p. 381-386 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

Development and characterization of a Yucatan miniature biomedical pig permanent middle cerebral artery occlusion stroke model

Platt, S. R., Holmes, S. P., Howerth, E. W., Duberstein, K. J. J., Dove, C. R., Kinder, H. A., Wyatt, E. L., Linville, A. V., Lau, V. W., Stice, S. L., Hill, W. D., Hess, D. C. & West, F. D., Mar 23 2014, In : Experimental and Translational Stroke Medicine. 6, 1, 5.

Research output: Contribution to journalArticle

26 Scopus citations

Gait analysis in a pre- and post-ischemic stroke biomedical pig model

Duberstein, K. J., Platt, S. R., Holmes, S. P., Dove, C. R., Howerth, E. W., Kent, M., Stice, S. L., Hill, W. D., Hess, D. C. & West, F. D., Feb 10 2014, In : Physiology and Behavior. 125, p. 8-16 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Rapamycin up-regulation of autophagy reduces infarct size and improves outcomes in both permanent MCAL, and embolic MCAO, murine models of stroke

Buckley, K. M., Hess, D. L., Sazonova, I. Y., Periyasamy-Thandavan, S., Barrett, J. R., Kirks, R., Grace, H., Kondrikova, G., Johnson, M. H., Hess, D. C., Schoenlein, P. V., Hoda, M. N. & Hill, W. D., Jun 21 2014, In : Experimental and Translational Stroke Medicine. 6, 1, 8.

Research output: Contribution to journalArticle

53 Scopus citations

Remote Ischemic Perconditioning is Effective After Embolic Stroke in Ovariectomized Female Mice

Hoda, M. N., Bhatia, K., Hafez, S. S., Johnson, M. H., Siddiqui, S., Ergul, A., Zaidi, S. K., Fagan, S. C. & Hess, D. C., Aug 1 2014, In : Translational Stroke Research. 5, 4, p. 484-490 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Remote Ischemic Postconditioning: Harnessing Endogenous Protection in a Murine Model of Vascular Cognitive Impairment

Khan, M. B., Hoda, M. N., Vaibhav, K., Giri, S., Wang, P., Waller, J. L., Ergul, A., Dhandapani, K. M., Fagan, S. C. & Hess, D. C., 2014, In : Translational Stroke Research. 6, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

47 Scopus citations
2013

Minocycline repurposing in critical illness: Focus on stroke

Liao, T. V., Forehand, C. C., Hess, D. C. & Fagan, S. C., 2013, In : Current Topics in Medicinal Chemistry. 13, 18, p. 2283-2290 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Remote limb preconditioning and postconditioning: Will it translate into a promising treatment for acute stroke?

Hess, D. C., Hoda, M. N. & Bhatia, K., Apr 2013, In : Stroke. 44, 4, p. 1191-1197 7 p.

Research output: Contribution to journalReview article

61 Scopus citations

Response to letter regarding article, "Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type"

Hoda, M. N., Hess, D. C., Ergul, A. & Fagan, S. C., Apr 2013, In : Stroke. 44, 4, p. e37

Research output: Contribution to journalLetter

2 Scopus citations

Simplified modified Rankin Scale questionnaire correlates with stroke severity

Bruno, A., Close, B., Switzer, J. A., Hess, D. C., Gross, H., Nichols, F. T. & Akinwuntan, A. E., Aug 1 2013, In : Clinical Rehabilitation. 27, 8, p. 724-727 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Teleneurology applications: Report of the telemedicine work group of the American Academy of Neurology

Wechsler, L. R., Tsao, J. W., Levine, S. R., Swain-Eng, R. J., Adams, R. J., Demaerschalk, B. M., Hess, D. C., Moro, E., Schwamm, L. H., Steffensen, S., Stern, B. J., Zuckerman, S. J., Bhattacharya, P., Davis, L. E., Yurkiewicz, I. R. & Alphonso, A. L., Feb 12 2013, In : Neurology. 80, 7, p. 670-676 7 p.

Research output: Contribution to journalReview article

81 Scopus citations

The history and future of telestroke

Hess, D. C. & Audebert, H. J., Jun 1 2013, In : Nature Reviews Neurology. 9, 6, p. 340-350 11 p.

Research output: Contribution to journalReview article

38 Scopus citations

Timeliness of intravenous thrombolysis via telestroke in Georgia

Bruno, A., Lanning, K. M., Gross, H., Hess, D. C., Nichols, F. T. & Switzer, J. A., Sep 1 2013, In : Stroke. 44, 9, p. 2620-2622 3 p.

Research output: Contribution to journalArticle

11 Scopus citations
2012

Amniotic fluid stem cells: A promising therapeutic resource for cell-based regenerative therapy

Antonucci, I., Pantalone, A., Tetè, S., Salini, V., Borlongan, C. V., Hess, D. & Stuppia, L., May 1 2012, In : Current Pharmaceutical Design. 18, 13, p. 1846-1863 18 p.

Research output: Contribution to journalReview article

44 Scopus citations

A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomes

Howard, G., Waller, J. L., Voeks, J. H., Howard, V. J., Jauch, E. C., Lees, K. R., Nichols, F. T., Rahlfs, V. W. & Hess, D. C., Mar 2012, In : Stroke. 43, 3, p. 664-669 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Clinical experience with three-factor prothrombin complex concentrate to reverse warfarin anticoagulation in intracranial hemorrhage

Switzer, J. A., Rocker, J., Mohorn, P., Waller, J. L., Hughes, D., Bruno, A., Nichols, F. T., Hess, D. C., Natrajan, K. & Fagan, S. C., Sep 1 2012, In : Stroke. 43, 9, p. 2500-2502 3 p.

Research output: Contribution to journalReview article

36 Scopus citations

Impact of primary stroke center certification on location of acute ischemic stroke care in Georgia

Switzer, J. A., Akinwuntan, A., Waller, J., Nichols, F. T., Hess, D. C. & Bruno, A., May 1 2012, In : Stroke. 43, 5, p. 1415-1417 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Minocycline: The search for a community hospital acute stroke therapy

Hess, D., Howard, V. & Howard, G., Jan 1 2012, In : Neurology India. 60, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

2 Scopus citations

Minocycline Prevents IL-6 Increase after Acute Ischemic Stroke

Switzer, J. A., Sikora, A., Ergul, A., Waller, J. L., Hess, D. C. & Fagan, S. C., Sep 2012, In : Translational Stroke Research. 3, 3, p. 364-368 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Permeating the blood brain barrier and Abrogating the inflammation in stroke: Implications for stroke therapy

Borlongan, C. V., Glover, L. E., Sanberg, P. R. & Hess, D. C., 2012, In : Current Pharmaceutical Design. 18, 25, p. 3670-3676 7 p.

Research output: Contribution to journalReview article

38 Scopus citations

Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke

Hoda, M. N., Siddiqui, S., Herberg, S., Periyasamy-Thandavan, S., Bhatia, K., Hafez, S. S., Johnson, M. H., Hill, W. D., Ergul, A., Fagan, S. C. & Hess, D. C., Oct 2012, In : Stroke. 43, 10, p. 2794-2799 6 p.

Research output: Contribution to journalArticle

77 Scopus citations