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Article
Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage
Ren, M. Q., Tidwell, J. A., Sharma, S. & Cowell, J. K., Jun 6 2012, In: PloS one. 7, 6, e38265.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization
Hawthorn, L. & Cowell, J. K., 2011, In: PloS one. 6, 4, e18941.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Celecoxib ameliorates seizure susceptibility in autosomal dominant lateral temporal epilepsy
Zhou, L., Zhou, L., Su, L. D., Cao, S. L., Xie, Y. J., Wang, N., Shao, C. Y., Wang, Y. N., Zhou, J. H., Cowell, J. K. & Shen, Y., Mar 28 2018, In: Journal of Neuroscience. 38, 13, p. 3346-3357 12 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease
Ren, M. Q. & Cowell, J. K., Jun 23 2011, In: Blood. 117, 25, p. 6837-6847 11 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
COP1 and GSK3β cooperate to promote c-Jun degradation and inhibit breast cancer cell tumorigenesis
Shao, J., Teng, Y., Padia, R., Hong, S., Noh, H., Xie, X., Mumm, J. S., Dong, Z., Ding, H. F., Cowell, J., Kim, J., Han, J. & Huang, S., Sep 2013, In: Neoplasia (United States). 15, 9, p. 1075-1085 11 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome
Chong, Y., Liu, Y., Lu, S., Cai, B., Qin, H., Chang, C. S., Ren, M., Cowell, J. K. & Hu, T., Apr 15 2020, In: International Journal of Cancer. 146, 8, p. 2243-2254 12 p.Research output: Contribution to journal › Article › peer-review
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Critical role of the WASF3 gene in JAK2/STAT3 regulation of cancer cell motility
Teng, Y., Ghoshal, P., Ngoka, L., Mei, Y. & Cowell, J. K., Sep 2013, In: Carcinogenesis. 34, 9, p. 1994-1999 6 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Development of ZMYM2-FGFR1 driven AML in human CD34+ cells in immunocompromised mice
Ren, M., Qin, H., Wu, Q., Savage, N. M., George, T. I. & Cowell, J. K., Aug 15 2016, In: International Journal of Cancer. 139, 4, p. 836-840 5 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome
Silva, M. J., Chang, C. S., Hu, T., Qin, H., Kitamura, E., Hawthorn, L., Ren, M. & Cowell, J. K., Dec 2019, In: Genomics. 111, 6, p. 1566-1573 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1– driven leukemogenesis
Hu, T., Chong, Y., Cai, B., Liu, Y., Lu, S. & Cowell, J. K., Nov 29 2019, In: Journal of Biological Chemistry. 294, 48, p. 18122-18130 9 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome
Liu, Y., Cai, B., Chong, Y., Zhang, H., Kemp, C. A., Lu, S., Chang, C. S., Ren, M., Cowell, J. K. & Hu, T., Oct 1 2020, In: Cell Death and Disease. 11, 10, 884.Research output: Contribution to journal › Article › peer-review
Open Access -
Dysregulated signaling pathways in the development of CNTRL-FGFR1–induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models
Ren, M., Qin, H., Kitamura, E. & Cowell, J. K., Aug 8 2013, In: Blood. 122, 6, p. 1007-1016 10 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Evaluating human cancer cell metastasis in zebrafish
Teng, Y., Xie, X., Walker, S., White, D. T., Mumm, J. S. & Cowell, J. K., Oct 4 2013, In: BMC Cancer. 13, 453.Research output: Contribution to journal › Article › peer-review
96 Scopus citations -
Evaluation of phosphatidylinositol-3-kinase catalytic subunit (PIK3CA) and epidermal growth factor receptor (EGFR) gene mutations in pancreaticobiliary adenocarcinoma
Weiss, G. A., Rossi, M. R., Khushalani, N. I., Lo, K., Gibbs, J. F., Bharthuar, A., Cowell, J. K. & Iyer, R., Mar 2013, In: Journal of Gastrointestinal Oncology. 4, 1, p. 20-29 10 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome
Hu, T., Wu, Q., Chong, Y., Qin, H., Poole, C. J., van Riggelen, J., Ren, M. & Cowell, J. K., Nov 1 2018, In: Leukemia. 32, 11, p. 2363-2373 11 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells
Teng, Y., Liu, M. & Cowell, J. K., Dec 15 2011, In: International Journal of Cancer. 129, 12, p. 2825-2835 11 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Genetic analysis of Down syndrome-associated heart defects in mice
Liu, C., Morishima, M., Yu, T., Matsui, S. I., Zhang, L., Fu, D., Pao, A., Costa, A. C., Gardiner, K. J., Cowell, J. K., Nowak, N. J., Parmacek, M. S., Liang, P., Baldini, A. & Yu, Y. E., Nov 2011, In: Human Genetics. 130, 5, p. 623-632 10 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
HIF1A induces expression of the WASF3 metastasis-associated gene under hypoxic conditions
Ghoshal, P., Teng, Y., Lesoon, L. A. & Cowell, J. K., Sep 15 2012, In: International Journal of Cancer. 131, 6, p. E905-E915Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation
Wang, X., Choi, J-H., Ding, J., Yang, L., Ngoka, L. C., Lee, E. J., Zha, Y., Mao, L., Jin, B., Ren, M., Cowell, J. K., Huang, S., Shi, H., Cui, H. & Ding, H., Nov 25 2013, In: BMC Genomics. 14, 1, 830.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
HSP90 and HSP70 Proteins are essential for stabilization and activation of WASF3 metastasis-promoting protein
Teng, Y., Ngoka, L., Mei, Y., Lesoon, L. & Cowell, J. K., Mar 23 2012, In: Journal of Biological Chemistry. 287, 13, p. 10051-10059 9 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
Inactivation of Lgi1 in murine neuronal precursor cells leads to dysregulation of axon guidance pathways
Silva, J., Hawthorn, L. & Cowell, J. K., Mar 2020, In: Genomics. 112, 2, p. 1167-1172 6 p.Research output: Contribution to journal › Article › peer-review
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LGI1: From zebrafish to human epilepsy
Cowell, J. K., Jan 1 2014, In: Progress in Brain Research. 213, C, p. 159-179 21 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Loss of ATF3 promotes hormone-induced prostate carcinogenesis and the emergence of CK5 + CK8 + epithelial cells
Wang, Z., Kim, J., Teng, Y., Ding, H., Zhang, J., Hai, T., Cowell, J. K. & Yan, C., Jul 7 2016, In: Oncogene. 35, 27, p. 3555-3564 10 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Loss of the BCR-FGFR1 GEF domain suppresses RhoA activation and enhances B-lymphomagenesis in mice
Hu, T., Chong, Y., Lu, S., Qin, H., Ren, M., Savage, N. M., Chang, C. S. & Cowell, J. K., Jan 1 2019, In: Cancer Research. 79, 1, p. 114-124 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior
Teng, Y., Xie, X., Walker, S., Saxena, M., Kozlowski, D. J., Mumm, J. S. & Cowell, J. K., Sep 16 2011, In: PloS one. 6, 9, e24596.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
MiR-339 promotes development of stem cell leukemia/lymphoma syndrome via downregulation of the BCL2L11 and BAX proapoptotic genes
Hu, T., Chong, Y., Lu, S., Wang, R., Qin, H., Silva, J., Kitamura, E., Chang, C. S., Hawthorn, L. A. & Cowell, J. K., Jul 1 2018, In: Cancer Research. 78, 13, p. 3522-3531 10 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein
Teng, Y., Ren, X., Li, H., Shull, A., Kim, J. & Cowell, J. K., Jan 21 2016, In: Oncogene. 35, 3, p. 333-343 11 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1
Ren, M., Hong, M., Liu, G., Wang, H., Patel, V. S., Biddinger, P. W., Silva, M. J., Cowell, J. K. & Hao, Z., Jun 2013, In: Oncology Reports. 29, 6, p. 2181-2190 10 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities
Ren, M., Qin, H., Ren, R. & Cowell, J. K., Jan 2013, In: Leukemia. 27, 1, p. 32-40 9 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model
Piranlioglu, R., Lee, E. M., Ouzounova, M., Bollag, R. J., Vinyard, A., Arbab, A. S., Marasco, D., Guzel, M., Cowell, J. K., Thangaraju, M., Chadli, A., Hassan, K. A., Wicha, M. S., Celis, E. & Korkaya, H., Dec 1 2019, In: Nature communications. 10, 1, 1430.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Selective inactivation of LGI1 in neuronal precursor cells leads to cortical dysplasia in mice
Silva, J., Qin, H. & Cowell, J. K., Feb 1 2019, In: Genesis. 57, 2, e23268.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases
Ren, M., Qin, H., Ren, R., Tidwell, J. & Cowell, J. K., Dec 1 2011, In: Cancer Research. 71, 23, p. 7312-7322 11 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models
Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In: Oncotarget. 7, 31, p. 49733-49742 10 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Targeting the WASF3-CYFIP1 complex using stapled peptides suppresses cancer cell invasion
Teng, Y., Bahassan, A., Dong, D., Hanold, L. E., Ren, X., Kennedy, E. J. & Cowell, J. K., Feb 15 2016, In: Cancer Research. 76, 4, p. 965-973 9 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis
Eisa, N. H., Jilani, Y., Kainth, K., Redd, P., Lu, S., Bougrine, O., Sater, H. A., Patwardhan, C. A., Shull, A., Shi, H., Liu, K., Elsherbiny, N. M., Eissa, L. A., El-Shishtawy, M. M., Horuzsko, A., Bollag, R., Maihle, N., Roig, J., Korkaya, H., Cowell, J. K. & 1 others, , Apr 5 2019, In: Journal of Biological Chemistry. 294, 14, p. 5246-5260 15 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
The MIR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase
Hu, T., Chong, Y., Qin, H., Kitamura, E., Chang, C. S., Silva, J., Ren, M. & Cowell, J. K., Apr 1 2018, In: Oncogene. 37, 14, p. 1926-1938 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20
Lee, E., Ouzounova, M., Piranlioglu, R., Ma, M. T., Guzel, M., Marasco, D., Chadli, A., Gestwicki, J. E., Cowell, J. K., Wicha, M. S., Hassan, K. A. & Korkaya, H., Jan 24 2019, In: Oncogene. 38, 4, p. 469-482 14 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development
Silva, J., Wang, G. & Cowell, J. K., May 13 2011, In: BMC Neuroscience. 12, 43.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
The WASF3-NCKAP1-CYFIP1 complex is essential for breast cancer metastasis
Teng, Y., Qin, H., Bahassan, A., Bendzunas, N. G., Kennedy, E. J. & Cowell, J. K., Sep 1 2016, In: Cancer Research. 76, 17, p. 5133-5142 10 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Transformation of human CD34+ hematopoietic progenitor cells with DEK-NUP214 induces AML in an immunocompromised mouse model
Qin, H., Malek, S., Cowell, J. K. & Ren, M., Oct 27 2016, In: Oncogene. 35, 43, p. 5686-5691 6 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility
Zhou, H. M., Fang, Y. Y., Weinberger, P. M., Ding, L. L., Cowell, J. K., Hudson, F. Z., Ren, M., Lee, J. R., Chen, Q. K., Su, H., Dynan, W. S. & Lin, Y., Feb 4 2016, In: BMC Cancer. 16, 1, 55.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Wasf3 Deficiency Reveals Involvement in Metastasis in a Mouse Model of Breast Cancer
Qin, H., Lu, S., Thangaraju, M. & Cowell, J. K., Dec 2019, In: American Journal of Pathology. 189, 12, p. 2450-2458 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling
Teng, Y., Pi, W., Wang, Y. & Cowell, J. K., Sep 1 2016, In: Oncogene. 35, 35, p. 4633-4640 8 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells
Teng, Y., Mei, Y., Hawthorn, L. & Cowell, J. K., Jan 9 2014, In: Oncogene. 33, 2, p. 203-211 9 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
Comment/debate
CML: a model disease with a defined oncogenic driver.
Hao, Z. & Cowell, J. K., Mar 1 2011, In: Clinical advances in hematology & oncology : H&O. 9, 3, p. 247-248 2 p.Research output: Contribution to journal › Comment/debate › peer-review
1 Scopus citations -
Correction: The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20 (Oncogene, (2019), 38, 4, (469-482), 10.1038/s41388-018-0472-0)
Lee, E., Ouzounova, M., Piranlioglu, R., Ma, M. T., Guzel, M., Marasco, D., Chadli, A., Gestwicki, J. E., Cowell, J. K., Wicha, M. S., Hassan, K. A. & Korkaya, H., Jul 11 2019, In: Oncogene. 38, 28, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Corrigendum to "WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, And MMP-9 expression" [Exp. Cell Res. 308 (2005) 135-145]
Sossey-Alaoui, K., Ranalli, T. A., Li, X., Bakin, A. V. & Cowell, J. K., Mar 10 2013, In: Experimental Cell Research. 319, 5, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Erratum: Genetic analysis of Down syndrome-associated heart defects in mice (Human Genetics DOI: 10.1007/s00439-011-0980-2)
Liu, C., Morishima, M., Yu, T., Matsui, S. I., Zhang, L., Fu, D., Pao, A., Costa, A. C., Gardiner, K. J., Cowell, J. K., Nowak, N. J., Parmacek, M. S., Liang, P., Baldini, A. & Yu, Y. E., Nov 2011, In: Human Genetics. 130, 5, p. 633 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Letter
A model of BCR-FGFR1 driven human AML in immunocompromised mice
Cowell, J. K., Qin, H., Chang, C. S., Kitamura, E. & Ren, M., Nov 1 2016, In: British Journal of Haematology. 175, 3, p. 542-545 4 p.Research output: Contribution to journal › Letter › peer-review
10 Scopus citations -
FGFR1OP2-FGFR1 induced myeloid leukemia and T-cell lymphoma in a mouse model
Qin, H., Wu, Q., Cowell, J. K. & Ren, M., 2016, In: Haematologica. 101, 3, p. e91-e94Research output: Contribution to journal › Letter › peer-review
8 Scopus citations