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• 2011

  Cell therapy for ischaemic stroke

  Hess, D. C. & Hill, W. D., Apr 2011, In: Cell Proliferation. 44, SUPPL. 1, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Transplantation
  • Neuroprotection
  • Cell- and Tissue-Based Therapy
  • Animal Models
  • Stroke
  12 Scopus citations

• Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex

  Risher, W. C., Lee, M. R., Fomitcheva, I. V., Hess, D. C. & Kirov, S. A., 2011, In: PloS one. 6, 7, e22351.

  Research output: Contribution to journal › Article › peer-review

  • Dibucaine
  • Depolarization
  • neocortex
  • Neocortex
  • rodents
  16 Scopus citations

• Impact of systems of care and blood pressure management on stroke outcomes

  Shulkin, D. J., Jewell, K. E., Alexandrov, A. W., Bernard, D. B., Brophy, G. M., Hess, D. C., Kohlbrenner, J., Martin-Schild, S., Mayer, S. A., Peacock, W. F., Qureshi, A. I., Sung, G. Y. & Lyles, A., Dec 1 2011, In: Population Health Management. 14, 6, p. 267-275 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Blood Pressure
  • Tissue Plasminogen Activator
  • Systems Analysis
  • Medicaid
  1 Scopus citations

• Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke

  Switzer, J. A., Hess, D. C., Ergul, A., Waller, J. L., MacHado, L. S., Portik-Dobos, V., Pettigrew, L. C., Clark, W. M. & Fagan, S. C., Sep 2011, In: Stroke. 42, 9, p. 2633-2635 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Matrix Metalloproteinase 9
  • Stroke
  • Plasminogen Activators
  • Thrombolytic Therapy
  82 Scopus citations

• Minocycline Development for Acute Ischemic Stroke

  Fagan, S. C., Cronic, L. E. & Hess, D. C., Jun 2011, In: Translational Stroke Research. 2, 2, p. 202-208 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Stroke
  • Clinical Trials
  • Tissue Plasminogen Activator
  • Tetracycline
  64 Scopus citations

• Recent advances in basic and translational stroke research

  Boltze, J., Kranz, A., Wagner, D. C., Reymann, K., Reiser, G. & Hess, D. C., Feb 1 2011, In: Expert Review of Neurotherapeutics. 11, 2, p. 199-202 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Translational Medical Research
  • Neuroprotection
  • Stroke
  • Cell- and Tissue-Based Therapy
  • Regeneration
  4 Scopus citations

• Response to letter by Lee regarding article, matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute stroke

  Switzer, J. A., Hess, D. C., Ergul, A. & Fagan, S. C., Oct 2011, In: Stroke. 42, 10, p. e567

  Research output: Contribution to journal › Letter › peer-review

• Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke

  Hoda, M. N., Li, W., Ahmad, A., Ogbi, S., Zemskova, M. A., Johnson, M. H., Ergul, A., Hill, W. D., Hess, D. C. & Sazonova, I. Y., Dec 16 2011, In: Experimental and Translational Stroke Medicine. 3, 1, 16.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Neuroprotection
  • Stroke
  • Matrix Metalloproteinases
  • Ovariectomy
  43 Scopus citations

• Simplified modified rankin scale questionnaire: Reproducibility over the telephone and validation with quality of life

  Bruno, A., Akinwuntan, A. E., Lin, C., Close, B., Davis, K., Baute, V., Aryal, T., Brooks, D., Hess, D. C., Switzer, J. A. & Nichols, F. T., Aug 2011, In: Stroke. 42, 8, p. 2276-2279 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Telephone
  • Quality of Life
  • Stroke
  • Neurology
  • Reproducibility of Results
  129 Scopus citations

• Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II

  Savitz, S. I., Chopp, M., Deans, R., Carmichael, S. T., Phinney, D., Wechsler, L., Aronowski, J., Bednar, M., Boltze, J., Borlongan, C., Chase, T., Corbett, D., Cox, C. S., Cramer, S., Fischkoff, S., Frank, J., Greenberg, D., Hess, D., Hong, K., Koga, M. & 15 others, Jones, T., Keating, A., Kokaia, Z., Mays, R., Mora, K., Pittenger, M., Sanberg, P., Schallert, T., Sinden, J., Snyder, E., Steinberg, G., Victor, S., Willing, A., Yankee, E. & Yavagal, D., Mar 1 2011, In: Stroke. 42, 3, p. 825-829 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell- and Tissue-Based Therapy
  • Stem Cells
  • Stroke
  • Industry
  • National Institutes of Health (U.S.)
  186 Scopus citations

• Stroke telepresence: Removing all geographic barriers

  Hess, D. C. & Switzer, J. A., Mar 29 2011, In: Neurology. 76, 13, p. 1121-1123 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  10 Scopus citations

• Stroke treatment academic industry roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies

  Albers, G. W., Goldstein, L. B., Hess, D. C., Wechsler, L. R., Furie, K. L., Gorelick, P. B., Hurn, P., Liebeskind, D. S., Nogueira, R. G. & Saver, J. L., Sep 2011, In: Stroke. 42, 9, p. 2645-2650 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Industry
  • Stroke
  • Reperfusion
  • Therapeutics
  • Thrombolytic Therapy
  138 Scopus citations

• Treatment of fever after stroke: Conflicting evidence

  Wrotek, S. E., Kozak, W. E., Hess, D. C. & Fagan, S. C., Nov 2011, In: Pharmacotherapy. 31, 11, p. 1085-1091 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Fever
  • Stroke
  • Body Temperature
  • Patient Harm
  • Antipyretics
  28 Scopus citations

• Use of telemedicine and helicopter transport to improve stroke care in remote locations

  Saler, M., Switzer, J. A. & Hess, D. C., Jun 2011, In: Current Treatment Options in Cardiovascular Medicine. 13, 3, p. 215-224 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Aircraft
  • Telemedicine
  • Stroke
  • X Ray Tomography
  • Ships
  16 Scopus citations

• Wisdom and determination in the ongoing pursuit of the ever-elusive neuroprotective agent

  Howard, G., Hess, D. C. & Howard, V. J., Jun 2011, In: Stroke. 42, 6, p. 1505-1506 2 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations
• 2012

  Amniotic fluid stem cells: A promising therapeutic resource for cell-based regenerative therapy

  Antonucci, I., Pantalone, A., Tetè, S., Salini, V., Borlongan, C. V., Hess, D. & Stuppia, L., May 2012, In: Current Pharmaceutical Design. 18, 13, p. 1846-1863 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Amniotic Fluid
  • Stem Cells
  • Cell Transplantation
  • Cell- and Tissue-Based Therapy
  • Fetal Stem Cells
  46 Scopus citations

• A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomes

  Howard, G., Waller, J. L., Voeks, J. H., Howard, V. J., Jauch, E. C., Lees, K. R., Nichols, F. T., Rahlfs, V. W. & Hess, D. C., Mar 2012, In: Stroke. 43, 3, p. 664-669 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Nonparametric Statistics
  • Investigational Therapies
  • Random Allocation
  • Stroke
  • Therapeutics
  50 Scopus citations

• Clinical experience with three-factor prothrombin complex concentrate to reverse warfarin anticoagulation in intracranial hemorrhage

  Switzer, J. A., Rocker, J., Mohorn, P., Waller, J. L., Hughes, D., Bruno, A., Nichols, F. T., Hess, D. C., Natrajan, K. & Fagan, S. C., Sep 2012, In: Stroke. 43, 9, p. 2500-2502 3 p.

  Research output: Contribution to journal › Review article › peer-review

  • prothrombin complex concentrates
  • Intracranial Hemorrhages
  • Subdural Hematoma
  • Factor VII
  • Subarachnoid Hemorrhage
  36 Scopus citations

• Impact of primary stroke center certification on location of acute ischemic stroke care in Georgia

  Switzer, J. A., Akinwuntan, A., Waller, J., Nichols, F. T., Hess, D. C. & Bruno, A., May 2012, In: Stroke. 43, 5, p. 1415-1417 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Certification
  • Stroke
  2 Scopus citations

• Minocycline: The search for a community hospital acute stroke therapy

  Hess, D., Howard, V. & Howard, G., Jan 2012, In: Neurology India. 60, 1, p. 1-2 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  2 Scopus citations

• Minocycline Prevents IL-6 Increase after Acute Ischemic Stroke

  Switzer, J. A., Sikora, A., Ergul, A., Waller, J. L., Hess, D. C. & Fagan, S. C., Sep 2012, In: Translational Stroke Research. 3, 3, p. 364-368 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Interleukin-6
  • Stroke
  • Nervous System
  • Anti-Inflammatory Agents
  20 Scopus citations

• Permeating the blood brain barrier and Abrogating the inflammation in stroke: Implications for stroke therapy

  Borlongan, C. V., Glover, L. E., Sanberg, P. R. & Hess, D. C., 2012, In: Current Pharmaceutical Design. 18, 25, p. 3670-3676 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Blood-Brain Barrier
  • Stroke
  • Inflammation
  • Cell- and Tissue-Based Therapy
  • Mannitol
  39 Scopus citations

• Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke

  Hoda, M. N., Siddiqui, S., Herberg, S., Periyasamy-Thandavan, S., Bhatia, K., Hafez, S. S., Johnson, M. H., Hill, W. D., Ergul, A., Fagan, S. C. & Hess, D. C., Oct 2012, In: Stroke. 43, 10, p. 2794-2799 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Tissue Plasminogen Activator
  • Stroke
  • Plasminogen Activators
  • Middle Cerebral Artery Infarction
  • Therapeutics
  81 Scopus citations
• 2013

  Minocycline repurposing in critical illness: Focus on stroke

  Liao, T. V., Forehand, C. C., Hess, D. C. & Fagan, S. C., 2013, In: Current Topics in Medicinal Chemistry. 13, 18, p. 2283-2290 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Critical Illness
  • Stroke
  • Vascular System Injuries
  • Neuroprotection
  22 Scopus citations

• Remote limb preconditioning and postconditioning: Will it translate into a promising treatment for acute stroke?

  Hess, D. C., Hoda, M. N. & Bhatia, K., Apr 2013, In: Stroke. 44, 4, p. 1191-1197 7 p.

  Research output: Contribution to journal › Review article › peer-review
  62 Scopus citations

• Response to letter regarding article, "Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type"

  Hoda, M. N., Hess, D. C., Ergul, A. & Fagan, S. C., Apr 2013, In: Stroke. 44, 4, p. e37

  Research output: Contribution to journal › Letter › peer-review
  2 Scopus citations

• Serendipitous recanalization of basilar artery occlusion

  Switzer, J. A., Forseen, S. E., Bruno, A. & Hess, D. C., Nov 1 2013, In: Journal of Stroke and Cerebrovascular Diseases. 22, 8, p. e671-e673

  Research output: Contribution to journal › Article › peer-review

  • Tenecteplase
  • Basilar Artery
  • Angiography
  • Tomography
  • Dysarthria

• Simplified modified Rankin Scale questionnaire correlates with stroke severity

  Bruno, A., Close, B., Switzer, J. A., Hess, D. C., Gross, H., Nichols, F. T. & Akinwuntan, A. E., Aug 1 2013, In: Clinical Rehabilitation. 27, 8, p. 724-727 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • National Institutes of Health (U.S.)
  • Registries
  • Community Hospital
  • Hospital Departments
  14 Scopus citations

• Teleneurology applications: Report of the telemedicine work group of the American Academy of Neurology

  Wechsler, L. R., Tsao, J. W., Levine, S. R., Swain-Eng, R. J., Adams, R. J., Demaerschalk, B. M., Hess, D. C., Moro, E., Schwamm, L. H., Steffensen, S., Stern, B. J., Zuckerman, S. J., Bhattacharya, P., Davis, L. E., Yurkiewicz, I. R. & Alphonso, A. L., Feb 12 2013, In: Neurology. 80, 7, p. 670-676 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Telemedicine
  • Neurology
  • Neurologists
  • Nervous System
  • Military Medicine
  86 Scopus citations

• The history and future of telestroke

  Hess, D. C. & Audebert, H. J., Jun 1 2013, In: Nature Reviews Neurology. 9, 6, p. 340-350 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • History
  • Stroke
  • Patient Care
  • Telecommunications
  • Rural Hospitals
  38 Scopus citations

• Timeliness of intravenous thrombolysis via telestroke in Georgia

  Bruno, A., Lanning, K. M., Gross, H., Hess, D. C., Nichols, F. T. & Switzer, J. A., Sep 2013, In: Stroke. 44, 9, p. 2620-2622 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Hospital Emergency Service
  • Stroke
  • Communication
  • Referral and Consultation
  • Head
  11 Scopus citations
• 2015

  Breaking out from the neuroprotective logjam: Combined treatment with remote ischemic conditioning and minocycline in the prehospital setting

  Park, J. M. & Hess, D. C., 2015, In: Neural Regeneration Research. 10, 4, p. 537-539 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Cell Therapy for Brain Injury

  Hess, D. C., Jan 1 2015, Springer International Publishing. 369 p.

  Research output: Book/Report › Book

  • Stem cells
  • Brain Injuries
  • Cell- and Tissue-Based Therapy
  • Brain
  • Stroke
  2 Scopus citations

• Induced pluripotent stem cells as a cell-based therapeutic in stroke

  Hess, D. C., Fakhri, N. & West, F. D., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 129-146 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Stem cells
  • Induced Pluripotent Stem Cells
  • Stroke
  • Regenerative Medicine
  • Homologous Transplantation
  1 Scopus citations

• Introduction to cell therapy in brain injury

  Hess, D. C., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 1-9 9 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Stem cells
  • Brain Injuries
  • Cell- and Tissue-Based Therapy
  • Brain
  • Bone

• Preconditioning and cell-based therapeutics

  Hess, D. C. & Hoda, MD. N., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 173-186 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Stem cells
  • Stem Cells
  • Tissue
  • Minocycline
  • Blood pressure

• Remote ischaemic conditioning-a new paradigm of self-protection in the brain

  Hess, D. C., Blauenfeldt, R. A., Andersen, G., Hougaard, K. D., Hoda, M. N., Ding, Y. & Ji, X., Dec 1 2015, In: Nature Reviews Neurology. 11, 12, p. 698-710 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Conditioning (Psychology)
  • Brain
  • Intracranial Arteriosclerosis
  • Stroke
  • Clinical Trials
  73 Scopus citations

• Telestroke: Variations in intravenous thrombolysis by spoke hospitals

  Switzer, J. A., Singh, R., Mathiassen, L., Waller, J. L., Adams, R. J. & Hess, D. C., 2015, In: Journal of Stroke and Cerebrovascular Diseases. 24, 4, p. 739-744 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Tissue Plasminogen Activator
  • Stroke
  • Hospital Emergency Service
  • Nurses
  • Health Facility Size
  4 Scopus citations
• 2016

  Addressing Disparities in Stroke Prevention for Atrial Fibrillation: Educational Opportunities

  Karcher, R., Berman, A. E., Gross, H., Hess, D. C., Jauch, E. C., Viser, P. E., Solenski, N. J. & Wolf, A. M. D., Jul 1 2016, In: American Journal of Medical Quality. 31, 4, p. 337-348 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Atrial Fibrillation
  • Stroke
  • Anticoagulants
  • Communication
  • Racism
  4 Scopus citations

• Humoral mediators of remote ischemic conditioning: Important role of eNOS/NO/nitrite

  Hess, D. C., Hoda, M. N. & Khan, M. B., Jan 1 2016, Acta Neurochirurgica, Supplementum. Springer-Verlag Wien, p. 45-48 4 p. (Acta Neurochirurgica, Supplementum; vol. 121).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  18 Scopus citations

• Lab-to-clinic application of stem cell therapy for stroke

  Borlongan, M. C., Kong, S. & Hess, D. C., Oct 3 2016, In: Chinese Neurosurgical Journal. 2, 1, 42.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cell- and Tissue-Based Therapy
  • Stem Cells
  • Stroke
  • Bone Marrow Cells
  • Clinical Trials
  1 Scopus citations

• Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke

  STAIR IX Collaborators, Aug 1 2016, In: Stroke. 47, 8, p. 2154-2159 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Industry
  • Meta-Analysis
  • Data Analysis
  • Stroke
  • Authorship
  4 Scopus citations
• 2018

  Chronic Remote Ischemic Conditioning Is Cerebroprotective and Induces Vascular Remodeling in a VCID Model

  Khan, M. B., Hafez, S., Hoda, M. N., Baban, B., Wagner, J., Awad, M. E., Sangabathula, H., Haigh, S., Elsalanty, M., Waller, J. L. & Hess, D. C., Feb 1 2018, In: Translational Stroke Research. 9, 1, p. 51-63 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Remodeling
  • Carotid Stenosis
  • Conditioning (Psychology)
  • Dementia
  • Cognitive Dysfunction
  15 Scopus citations

• Expansion of telestroke services improves quality of care provided in super rural areas

  Zhang, D., Wang, G., Zhu, W., Thapa, J. R., Switzer, J. A., Hess, D. C., Smith, M. L. & Ritchey, M. D., Dec 2018, In: Health Affairs. 37, 12, p. 2005-2013 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Quality of Health Care
  • Tissue Plasminogen Activator
  • Stroke
  • Thrombectomy
  • Fee-for-Service Plans
  6 Scopus citations

• Human neural stem cell extracellular vesicles improve recovery in a porcine model of ischemic stroke

  Webb, R. L., Kaiser, E. E., Jurgielewicz, B. J., Spellicy, S., Scoville, S. L., Thompson, T. A., Swetenburg, R. L., Hess, D. C., West, F. D. & Stice, S. L., 2018, In: Stroke. 49, 5, p. 1248-1256 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles
  • Neural Stem Cells
  • Swine
  • Middle Cerebral Artery Infarction
  • Stroke
  58 Scopus citations

• Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model

  Webb, R. L., Kaiser, E. E., Scoville, S. L., Thompson, T. A., Fatima, S., Pandya, C., Sriram, K., Swetenburg, R. L., Vaibhav, K., Arbab, A. S., Baban, B., Dhandapani, K. M., Hess, D. C., Hoda, M. N. & Stice, S. L., Oct 1 2018, In: Translational Stroke Research. 9, 5, p. 530-539 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Vesicles
  • Neural Stem Cells
  • Stroke
  • Rodentia
  • Mesenchymal Stem Cells
  46 Scopus citations

• Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation

  Vaibhav, K., Braun, M., Khan, M. B., Fatima, S., Saad, N., Shankar, A., Khan, Z. T., Harris, R. B. S., Yang, Q., Huo, Y., Arbab, A. S., Giri, S., Alleyne, C. H., Vender, J. R., Hess, D. C., Baban, B., Hoda, M. N. & Dhandapani, K. M., Oct 1 2018, In: Journal of Experimental Medicine. 215, 10, p. 2636-2654 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ischemic Postconditioning
  • Hematoma
  • Extremities
  • Cerebral Hemorrhage
  • Metabolic Inactivation
  18 Scopus citations

• Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization

  Braun, M., Khan, Z. T., Khan, M. B., Kumar, M., Ward, A., Achyut, B. R., Arbab, A. S., Hess, D. C., Hoda, M. N., Baban, B., Dhandapani, K. M. & Vaibhav, K., Feb 2018, In: Brain, Behavior, and Immunity. 68, p. 224-237 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cannabinoid Receptors
  • Traumatic Brain Injury
  • Macrophages
  • Endocannabinoids
  • iodopravadoline
  26 Scopus citations

• Stem Cell Therapy in Cerebrovascular Disease

  Nahhas, M. I. & Hess, D. C., Nov 1 2018, In: Current Treatment Options in Neurology. 20, 11, 49.

  Research output: Contribution to journal › Review article › peer-review

  • Cerebrovascular Disorders
  • Cell- and Tissue-Based Therapy
  • Stem Cells
  • Clinical Trials
  • Stroke
  2 Scopus citations
• 2019

  Impact of Participation in a Telestroke Network on Clinical Outcomes

  Zhang, D., Shi, L., Ido, M. S., Green, D. E., Li, Y., Su, D. & Hess, D. C., Jan 1 2019, In: Circulation. Cardiovascular quality and outcomes. 12, 1, p. e005147

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Tissue Plasminogen Activator
  • Propensity Score
  • Observational Studies
  • Hospital Bed Capacity
  7 Scopus citations