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  Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA

  Kondo, S., Kondo, Y., Li, G., Silverman, R. H. & Cowell, J. K., Jun 25 1998, In: Oncogene. 16, 25, p. 3323-3330 8 p.

  Research output: Contribution to journal › Article › peer-review
  195 Scopus citations

• Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow.

  Klibanov, A. L., Rychak, J. J., Yang, W. C., Alikhani, S., Li, B., Acton, S., Lindner, J. R., Ley, K. & Kaul, S., Nov 2006, In: Contrast Media and Molecular Imaging. 1, 6, p. 259-266 8 p.

  Research output: Contribution to journal › Article › peer-review
  146 Scopus citations

• targetHub: A programmable interface for miRNA-gene interactions

  Manyam, G., Ivan, C., Calin, G. A. & Coombes, K. R., Oct 15 2013, In: Bioinformatics. 29, 20, p. 2657-2658 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• Targeting ABL and SRC kinases in chronic myeloid leukemia: Experience with dasatinib

  Quintás-Cardama, A., Kantarjian, H. & Cortes, J., Dec 2006, In: Future Oncology. 2, 6, p. 655-665 11 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas

  Nair, S., Curiel, D. T., Rajaratnam, V., Thota, C. & Al-Hendy, A., Sep 2013, In: Human Reproduction. 28, 9, p. 2398-2406 9 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Targeting Anti-Angiogenic VEGF₁₆₅b–VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models

  Kuppuswamy, S., Annex, B. H. & Ganta, V. C., Sep 2022, In: Cells. 11, 17, 2676.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy

  Zhou, H., Lei, X., Yan, Y., Lydic, T., Li, J., Weintraub, N. L., Su, H. & Chen, W., Jul 25 2019, In: JCI Insight. 4, 14, e129781.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Scopus citations

• Targeting Bone Marrow to Potentiate the Anti-Tumor Effect of Tyrosine Kinase Inhibitor in Preclinical Rat Model of Human Glioblastoma

  Shaaban, S., Alsulami, M., Arbab, S. A., Ara, R., Shankar, A., Iskander, A., Angara, K., Jain, M., Bagher-Ebadian, H., Achyut, B. R. & Arbab, A. S., Jul 19 2016, In: International Journal of Cancer Research. 12, 2, p. 69-81 13 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

  Kakarala, M., Brenner, D. E., Korkaya, H., Cheng, C., Tazi, K., Ginestier, C., Liu, S., Dontu, G. & Wicha, M. S., Aug 2010, In: Breast Cancer Research and Treatment. 122, 3, p. 777-785 9 p.

  Research output: Contribution to journal › Article › peer-review
  386 Scopus citations

• Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2⁺ Breast Cancer

  Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In: Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  53 Scopus citations

• Targeting endothelial barrier dysfunction caused by circulating bacterial and mitochondrial n-formyl peptides with deformylase

  Martinez-Quinones, P., Komic, A., McCarthy, C. G., Webb, R. C. & Wenceslau, C. F., 2019, In: Frontiers in immunology. 10, JUN, 1270.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Scopus citations

• Targeting Fc Receptor-Mediated Effects and the “Don’t Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer

  Tian, L., Xu, B., Teng, K. Y., Song, M., Zhu, Z., Chen, Y., Wang, J., Zhang, J., Feng, M., Kaur, B., Rodriguez, L., Caligiuri, M. A. & Yu, J., Jan 1 2022, In: Clinical Cancer Research. 28, 1, p. 201-214 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models

  Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In: Oncotarget. 7, 31, p. 49733-49742 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma

  Kumai, T., Ohkuri, T., Nagato, T., Matsuda, Y., Oikawa, K., Aoki, N., Kimura, S., Celis, E., Harabuchi, Y. & Kobayashi, H., Nov 5 2015, In: Scientific reports. 5, 16280.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation

  Woan, K. V., Lienlaf, M., Perez-Villaroel, P., Lee, C., Cheng, F., Knox, T., Woods, D. M., Barrios, K., Powers, J., Sahakian, E., Wang, H. W., Canales, J., Marante, D., Smalley, K. S. M., Bergman, J., Seto, E., Kozikowski, A., Pinilla-Ibarz, J., Sarnaik, A., Celis, E., & 3 othersWeber, J., Sotomayor, E. M. & Villagra, A., Aug 1 2015, In: Molecular Oncology. 9, 7, p. 1447-1457 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  89 Scopus citations

• Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia

  Ganguly, S., Home, T., Yacoub, A., Kambhampati, S., Shi, H., Dandawate, P., Padhye, S., Saluja, A. K., McGuirk, J. & Rao, R., 2015, In: Oncotarget. 6, 31, p. 31767-31779 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations

• Targeting hyaluronic acid synthase-3 (HAS3) for the treatment of advanced renal cell carcinoma

  Wang, J., Jordan, A. R., Zhu, H., Hasanali, S. L., Thomas, E., Lokeshwar, S. D., Morera, D. S., Alexander, S., McDaniels, J., Sharma, A., Aguilar, K., Sarcan, S., Zhu, T., Soloway, M. S., Terris, M. K., Thangaraju, M., Lopez, L. E. & Lokeshwar, V. B., Dec 2022, In: Cancer Cell International. 22, 1, 421.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Targeting hyaluronidase for cancer therapy: Antitumor activity of sulfated hyaluronic acid in prostate cancer cells

  Benitez, A., Yates, T. J., Lopez, L. E., Cerwinka, W. H., Bakkar, A. & Lokeshwar, V. B., Jun 15 2011, In: Cancer Research. 71, 12, p. 4085-4095 11 p.

  Research output: Contribution to journal › Article › peer-review
  112 Scopus citations

• Targeting IL11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens

  Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C., Bover, L., Sun, Y., Kuniyasu, A., Driessen, W. H. P., Cardó-Vila, M., Rietz, C., Zurita, A. J., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Calin, G. A., Koivunen, E., Arap, W. & Pasqualini, R., Jul 1 2015, In: Clinical Cancer Research. 21, 13, p. 3041-3051 11 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Targeting insomnia symptoms as a path to reduction of suicide risk: the role of cognitive behavioral therapy for insomnia (CBT-I): the role of cognitive behavioral therapy for insomnia (CBT-I)

  McCall, W. V., Dec 12 2022, In: Sleep. 45, 12

  Research output: Contribution to journal › Article › peer-review

• Targeting intrinsically disordered regions facilitates discovery of calcium channels 3.2 inhibitory peptides for adeno-associated virus-mediated peripheral analgesia

  Shin, S. M., Lauzadis, J., Itson-Zoske, B., Cai, Y., Fan, F., Natarajan, G. K., Kwok, W. M., Puopolo, M., Hogan, Q. H. & Yu, H., Dec 1 2022, In: Pain. 163, 12, p. 2466-2484 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting lymphotoxin β receptor with tumor-specific T lymphocytes for tumor regression

  Yang, D., Ud Din, N., Browning, D. D., Abrams, S. I. & Liu, K., Sep 1 2007, In: Clinical Cancer Research. 13, 17, p. 5202-5210 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Scopus citations

• Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers

  Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E., Melnik, M. K., Korkaya, H., Maroun, C. R., Christensen, J. G., Steensma, M. R., Boerner, J. L. & Graveel, C. R., 2016, In: Oncotarget. 7, 43, p. 69903-69915 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  40 Scopus citations

• Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease

  Bachmann, C., Klibanov, A. L., Olson, T. S., Sonnenschein, J. R., Rivera-Nieves, J., Cominelli, F., Ley, K. F., Lindner, J. R. & Pizarro, T. T., Jan 2006, In: Gastroenterology. 130, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Article › peer-review
  99 Scopus citations

• Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function

  Sagar, A., Arif, E., Solanki, A. K., Srivastava, P., Janech, M. G., Kim, S. H., Lipschutz, J. H., Kwon, S. H., Ashish & Nihalani, D., Dec 1 2017, In: Scientific reports. 7, 1, 12047.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Scopus citations

• Targeting neuropilin-1 in human leukemia and lymphoma

  Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C. E., Zurita, A. J., Kuniyasu, A., Eckhardt, B. L., Marini, F. C., Lichtiger, B., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Koivunen, E., Arap, W. & Pasqualini, R., Jan 20 2011, In: Blood. 117, 3, p. 920-927 8 p.

  Research output: Contribution to journal › Article › peer-review
  87 Scopus citations

• Targeting nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of parkinson's disease

  Kaidery, N. A., Banerjee, R., Yang, L., Smirnova, N. A., Hushpulian, D. M., Liby, K. T., Williams, C. R., Yamamoto, M., Kensler, T. W., Ratan, R. R., Sporn, M. B., Beal, M. F., Gazaryan, I. G. & Thomas, B., Jan 10 2013, In: Antioxidants and Redox Signaling. 18, 2, p. 139-157 19 p.

  Research output: Contribution to journal › Article › peer-review
  125 Scopus citations

• Targeting of 12/15-Lipoxygenase in retinal endothelial cells, but not in monocytes/macrophages, attenuates high glucose-induced retinal leukostasis

  Ibrahim, A. S., Saleh, H., El-Shafey, M., Hussein, K. A., El-Masry, K., Baban, B., Sheibani, N., Wang, M. H., Tawfik, A. & Al-Shabrawey, M., Jun 1 2017, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1862, 6, p. 636-645 10 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma

  Salnikov, A. V., Groth, A., Apel, A., Kallifatidis, G., Beckermann, B. M., Khamidjanov, A., Ryschich, E., Büchler, M. W., Herr, I. & Moldenhauer, G., Sep 2009, In: Journal of Cellular and Molecular Medicine. 13, 9 B, p. 4023-4033 11 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Targeting of DC-SIGN on human dendritic cells by minor fimbriated Porphyromonas gingivalis strains elicits a distinct effector T cell response

  Zeituni, A. E., Jotwani, R., Carrion, J. & Cutler, C. W., Nov 1 2009, In: Journal of Immunology. 183, 9, p. 5694-5704 11 p.

  Research output: Contribution to journal › Article › peer-review
  61 Scopus citations

• Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release

  Fulton, D., Babbitt, R., Zoellner, S., Fontana, J., Acevedo, L., McCabe, T. J., Iwakiri, Y. & Sessa, W. C., Jul 16 2004, In: Journal of Biological Chemistry. 279, 29, p. 30349-30357 9 p.

  Research output: Contribution to journal › Article › peer-review
  108 Scopus citations

• Targeting of pancreatic and prostate cancer stem cell characteristics by Crambe crambe marine sponge extract

  Ottinger, S., Klöppel, A., Rausch, V., Liu, L., Kallifatidis, G., Gross, W., Gebhard, M. M., Brümmer, F. & Herr, I., Apr 1 2012, In: International Journal of Cancer. 130, 7, p. 1671-1681 11 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma

  Ohara, K., Ohkuri, T., Kumai, T., Nagato, T., Nozaki, Y., Ishibashi, K., Kosaka, A., Nagata, M., Harabuchi, S., Ohara, M., Oikawa, K., Aoki, N., Harabuchi, Y., Celis, E. & Kobayashi, H., Sep 2 2018, In: OncoImmunology. 7, 9, e1466771.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  12 Scopus citations

• Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

  Paz, K., Flynn, R., Du, J., Tannheimer, S., Johnson, A. J., Dong, S., Stark, A. K., Okkenhaug, K., Panoskaltsis-Mortari, A., Sage, P. T., Sharpe, A. H., Luznik, L., Ritz, J., Soiffer, R. J., Cutler, C. S., Koreth, J., Antin, J. H., Miklos, D. B., MacDonald, K. P., Hill, G. R., & 10 othersMaillard, I., Serody, J. S., Murphy, W. J., Munn, D. H., Feser, C., Zaiken, M., Vanhaesebroeck, B., Turka, L. A., Byrd, J. C. & Blazar, B. R., Jun 2019, In: American Journal of Transplantation. 19, 6, p. 1820-1830 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Targeting polyamine oxidase to prevent excitotoxicity-induced retinal neurodegeneration

  Pichavaram, P., Palani, C. D., Patel, C., Xu, Z., Shosha, E., Fouda, A. Y., Caldwell, R. B. & Narayanan, S. P., 2019, In: Frontiers in Neuroscience. 13, JAN, 956.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair

  Fouda, A. Y., Xu, Z., Suwanpradid, J., Rojas, M., Shosha, E., Lemtalsi, T., Patel, C., Xing, J., Zaidi, S. A., Zhi, W., Stansfield, B. K., Cheng, P. N. M., Narayanan, S. P., Caldwell, R. W. & Caldwell, R. B., Aug 2022, In: Cell Death and Disease. 13, 8, 745.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress

  Zhang, Y., Lai, J., Du, Z., Gao, J., Yang, S., Gorityala, S., Xiong, X., Deng, O., Ma, Z., Yan, C., Susana, G., Xu, Y. & Zhang, J., Jun 7 2016, In: Oncotarget. 7, 23, p. 34688-34702 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Scopus citations

• Targeting ras activity prevented amyloid beta-induced aberrant neuronal cell cycle re-entry and death

  Köseoğlu, M. M., Özdilek, B. A., Djakbarova, U. & Gülüşür, A., Nov 1 2016, In: Current Alzheimer Research. 13, 11, p. 1267-1276 10 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Targeting serum glucocorticoid-regulated kinase-1 in squamous cell carcinoma of the head and neck: A novel modality of local control

  Berdel, H. O., Yin, H., Liu, J. Y., Grochowska, K., Middleton, C., Yanasak, N. E., Abdelsayed, R. A., Berdel, W. E., Mozaffari, M. S., Yu, J. C. & Baban, B., Dec 8 2014, In: PloS one. 9, 12, e113795.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy

  Hong, Z., Liu, T., Wan, L., Fa, P., Kumar, P., Cao, Y., Prasad, C. B., Qiu, Z., Liu, J., Wang, H., Li, Z., Wang, Q. E., Guo, P., Guo, D., Yilmaz, A. S., Lu, L., Papandreou, I., Jacob, N. K., Yan, C., Zhang, X., & 3 othersShe, Q. B., Ma, Z. & Zhang, J., Apr 1 2022, In: Cancer Research. 82, 7, p. 1298-1312 15 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Targeting T-cell malignancies using anti-CD4 CAR NK-92 cells

  Pinz, K. G., Yakaboski, E., Jares, A., Liu, H., Firor, A. E., Chen, K. H., Wada, M., Salman, H. S., Tse, W., Hagag, N., Lan, F., Leung, E. L. H., Jiang, X. & Ma, Y., 2017, In: Oncotarget. 8, 68, p. 112783-112796 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  65 Scopus citations

• Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

  Nhili, R., Peixoto, P., Depauw, S., Flajollet, S., Dezitter, X., Munde, M. M., Ismail, M. A., Kumar, A., Farahat, A. A., Stephens, C. E., Duterque-Coquillaud, M., David Wilson, W., Boykin, D. W. & David-Cordonnier, M. H., Jan 2013, In: Nucleic Acids Research. 41, 1, p. 125-138 14 p.

  Research output: Contribution to journal › Article › peer-review
  55 Scopus citations

• Targeting the most important complications in vascular surgery

  Bennett, K. M., Kent, K. C., Schumacher, J., Greenberg, C. C. & Scarborough, J. E., Mar 1 2017, In: Journal of Vascular Surgery. 65, 3, p. 793-803 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations

• Targeting the MYC oncogene in burkitt lymphoma through HSP90 inhibition

  Poole, C. J., Zheng, W., Lee, H., Young, D., Lodh, A., Chadli, A. & van Riggelen, J., Nov 16 2018, In: Cancers. 10, 11, 448.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Scopus citations

• Targeting the sodium-dependent multivitamin transporter (SMVT) for improving the oral absorption properties of a retro-inverso Tat nonapeptide

  Ramanathan, S., Pooyan, S., Stein, S., Prasad, P. D., Wang, J., Leibowitz, M. J., Ganapathy, V. & Sinko, P. J., 2001, In: Pharmaceutical Research. 18, 7, p. 950-956 7 p.

  Research output: Contribution to journal › Article › peer-review
  52 Scopus citations

• Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: Effects on radiation therapy

  Li, L., Rojiani, A. & Siemann, D. W., Nov 1 1998, In: International Journal of Radiation Oncology Biology Physics. 42, 4, p. 899-903 5 p.

  Research output: Contribution to journal › Article › peer-review
  132 Scopus citations

• Targeting the WASF3-CYFIP1 complex using stapled peptides suppresses cancer cell invasion

  Teng, Y., Bahassan, A., Dong, D., Hanold, L. E., Ren, X., Kennedy, E. J. & Cowell, J. K., Feb 15 2016, In: Cancer Research. 76, 4, p. 965-973 9 p.

  Research output: Contribution to journal › Article › peer-review
  43 Scopus citations

• Targeting transforming growth factor-β signaling in liver metastasis of colon cancer

  Zhang, B., Halder, S. K., Zhang, S. & Datta, P. K., May 8 2009, In: Cancer Letters. 277, 1, p. 114-120 7 p.

  Research output: Contribution to journal › Article › peer-review
  110 Scopus citations

• Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells

  Cui, Y., Golob, J., Kelleher, E., Ye, Z., Pardoll, D. & Cheng, L., Jan 15 2002, In: Blood. 99, 2, p. 399-408 10 p.

  Research output: Contribution to journal › Article › peer-review
  115 Scopus citations

• Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches

  Shekhar, S., Cunningham, M. W., Pabbidi, M. R., Wang, S., Booz, G. W. & Fan, F., Aug 15 2018, In: European Journal of Pharmacology. 833, p. 531-544 14 p.

  Research output: Contribution to journal › Article › peer-review