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• AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia

  Poh, L., Fann, D. Y., Wong, P., Lim, H. M., Foo, S. L., Kang, S. W., Rajeev, V., Selvaraji, S., Iyer, V. R., Parathy, N., Khan, M. B., Hess, D. C., Jo, D. G., Drummond, G. R., Sobey, C. G., Lai, M. K. P., Chen, C. L. H., Lim, L. H. K. & Arumugam, T. V., 2020, (Accepted/In press) In: Molecular Psychiatry.

  Research output: Contribution to journal › Article › peer-review

  • Inflammasomes
  • Vascular Dementia
  • Cognitive Dysfunction
  • Pyroptosis
  • Carotid Stenosis
  1 Scopus citations

• A multicentre, randomised, sham-controlled trial on REmote iSchemic conditioning In patients with acute STroke (RESIST) – Rationale and study design

  Blauenfeldt, R. A., Hjort, N., Gude, M. F., Behrndtz, A. B., Fisher, M., Valentin, J. B., Kirkegaard, H., Johnsen, S. P., Hess, D. C. & Andersen, G., Mar 1 2020, In: European Stroke Journal. 5, 1, p. 94-101 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stroke
  • Randomized Controlled Trials
  • Cerebral Hemorrhage
  • Economic Inflation
  • Blood Pressure
  1 Scopus citations

• Breaking out from the neuroprotective logjam: Combined treatment with remote ischemic conditioning and minocycline in the prehospital setting

  Park, J. M. & Hess, D. C., 2015, In: Neural Regeneration Research. 10, 4, p. 537-539 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Cannabidiol (CBD) modulation of apelin in acute respiratory distress syndrome

  Salles, É. L., Khodadadi, H., Jarrahi, A., Ahluwalia, M., Paffaro, V. A., Costigliola, V., Yu, J. C., Hess, D. C., Dhandapani, K. M. & Baban, B., Nov 2020, In: Journal of Cellular and Molecular Medicine. 24, 21, p. 12869-12872 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apelin
  • Cannabidiol
  • Adult Respiratory Distress Syndrome
  • Poly I-C
  • Therapeutics
  4 Scopus citations

• Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA

  Khodadadi, H., Salles, É. L., Jarrahi, A., Chibane, F., Costigliola, V., Yu, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M. & Baban, B., Sep 1 2020, In: Cannabis and Cannabinoid Research. 5, 3, p. 197-201 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Cannabidiol
  • Adult Respiratory Distress Syndrome
  • Virus Diseases
  • RNA
  • Cytokines
  7 Scopus citations

• Cell Therapy for Brain Injury

  Hess, D. C., Jan 1 2015, Springer International Publishing. 369 p.

  Research output: Book/Report › Book

  • Stem cells
  • Brain Injuries
  • Cell- and Tissue-Based Therapy
  • Brain
  • Stroke
  2 Scopus citations

• Cell therapy for ischaemic stroke

  Hess, D. C. & Hill, W. D., Apr 2011, In: Cell Proliferation. 44, SUPPL. 1, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Transplantation
  • Neuroprotection
  • Cell- and Tissue-Based Therapy
  • Animal Models
  • Stroke
  12 Scopus citations

• Collaterals 2016: Translating the collaterome around the globe

  for the Collaterals 2016 Consortium, Jun 2017, In: International Journal of Stroke. 12, 4, p. 338-342 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Congresses
  • Videoconferencing
  • Collateral Circulation
  • Triage
  4 Scopus citations

• COVID-19-Related Stroke

  Hess, D. C., Eldahshan, W. & Rutkowski, E., Jun 1 2020, In: Translational Stroke Research. 11, 3, p. 322-325 4 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • angiotensin converting enzyme 2
  • SARS Virus
  • Angiotensin II
  • Stroke
  • Peptidyl-Dipeptidase A
  107 Scopus citations

• Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex

  Risher, W. C., Lee, M. R., Fomitcheva, I. V., Hess, D. C. & Kirov, S. A., 2011, In: PloS one. 6, 7, e22351.

  Research output: Contribution to journal › Article › peer-review

  • Dibucaine
  • Depolarization
  • neocortex
  • Neocortex
  • rodents
  16 Scopus citations

• Establishment of an internationally agreed minimum data set for acute telestroke

  Cadilhac, D. A., Bagot, K. L., Demaerschalk, B. M., Hubert, G., Schwamm, L., Watkins, C. L., Lightbody, C. E., Kim, J., Vu, M., Pompeani, N., Switzer, J., Caudill, J., Estrada, J., Viswanathan, A., Hubert, N., Ohannessian, R., Hargroves, D., Roberts, N., Ingall, T., Hess, D. C. & 3 others, Ranta, A., Padma, V. & Bladin, C. F., 2020, (Accepted/In press) In: Journal of Telemedicine and Telecare.

  Research output: Contribution to journal › Article › peer-review

  • Datasets
  • Australasia
  • Referral and Consultation
  • Telecommunications
  • Delphi Technique
  3 Scopus citations

• Impact of Participation in a Telestroke Network on Clinical Outcomes

  Zhang, D., Shi, L., Ido, M. S., Green, D. E., Li, Y., Su, D. & Hess, D. C., Jan 1 2019, In: Circulation. Cardiovascular quality and outcomes. 12, 1, p. e005147

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Tissue Plasminogen Activator
  • Propensity Score
  • Observational Studies
  • Hospital Bed Capacity
  12 Scopus citations

• Impact of systems of care and blood pressure management on stroke outcomes

  Shulkin, D. J., Jewell, K. E., Alexandrov, A. W., Bernard, D. B., Brophy, G. M., Hess, D. C., Kohlbrenner, J., Martin-Schild, S., Mayer, S. A., Peacock, W. F., Qureshi, A. I., Sung, G. Y. & Lyles, A., Dec 1 2011, In: Population Health Management. 14, 6, p. 267-275 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Blood Pressure
  • Tissue Plasminogen Activator
  • Systems Analysis
  • Medicaid
  1 Scopus citations

• Induced Pluripotent Stem Cell-Derived Neural Stem Cell Therapy Enhances Recovery in an Ischemic Stroke Pig Model

  Baker, E. W., Platt, S. R., Lau, V. W., Grace, H. E., Holmes, S. P., Wang, L., Duberstein, K. J., Howerth, E. W., Kinder, H. A., Stice, S. L., Hess, D. C., Mao, H. & West, F. D., Dec 1 2017, In: Scientific reports. 7, 1, 10075.

  Research output: Contribution to journal › Article › peer-review

  • Induced Pluripotent Stem Cells
  • Neural Stem Cells
  • Cell- and Tissue-Based Therapy
  • Swine
  • Stroke
  44 Scopus citations

• Induced pluripotent stem cells as a cell-based therapeutic in stroke

  Hess, D. C., Fakhri, N. & West, F. D., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 129-146 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Stem cells
  • Induced Pluripotent Stem Cells
  • Stroke
  • Regenerative Medicine
  • Homologous Transplantation
  1 Scopus citations

• Introduction to cell therapy in brain injury

  Hess, D. C., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 1-9 9 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Stem cells
  • Brain Injuries
  • Cell- and Tissue-Based Therapy
  • Brain
  • Bone

• Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke

  Switzer, J. A., Hess, D. C., Ergul, A., Waller, J. L., MacHado, L. S., Portik-Dobos, V., Pettigrew, L. C., Clark, W. M. & Fagan, S. C., Sep 2011, In: Stroke. 42, 9, p. 2633-2635 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Matrix Metalloproteinase 9
  • Stroke
  • Plasminogen Activators
  • Thrombolytic Therapy
  84 Scopus citations

• Minocycline Development for Acute Ischemic Stroke

  Fagan, S. C., Cronic, L. E. & Hess, D. C., Jun 2011, In: Translational Stroke Research. 2, 2, p. 202-208 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Stroke
  • Clinical Trials
  • Tissue Plasminogen Activator
  • Tetracycline
  67 Scopus citations

• Minocycline in acute cerebral hemorrhage an early phase randomized trial

  Fouda, A. Y., Newsome, A. S., Spellicy, S., Waller, J. L., Zhi, W., Hess, D. C., Ergul, A., Edwards, D. J., Fagan, S. C. & Switzer, J. A., Oct 2017, In: Stroke. 48, 10, p. 2885-2887 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Cerebral Hemorrhage
  • Half-Life
  • Pharmacokinetics
  • Anti-Inflammatory Agents
  26 Scopus citations

• Minocycline repurposing in critical illness: Focus on stroke

  Liao, T. V., Forehand, C. C., Hess, D. C. & Fagan, S. C., 2013, In: Current Topics in Medicinal Chemistry. 13, 18, p. 2283-2290 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Critical Illness
  • Stroke
  • Vascular System Injuries
  • Neuroprotection
  22 Scopus citations

• Neurological consequences of COVID-19: What have we learned and where do we go from here?

  Jarrahi, A., Ahluwalia, M., Khodadadi, H., Da Silva Lopes Salles, E., Kolhe, R., Hess, D. C., Vale, F., Kumar, M., Baban, B., Vaibhav, K. & Dhandapani, K. M., Sep 30 2020, In: Journal of Neuroinflammation. 17, 1, 286.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus
  • SARS Virus
  • Dysgeusia
  • Middle East Respiratory Syndrome Coronavirus
  • Respiratory Center
  10 Scopus citations

• Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury

  Vaibhav, K., Braun, M., Alverson, K., Khodadadi, H., Kutiyanawalla, A., Ward, A., Banerjee, C., Sparks, T., Malik, A., Rashid, M. H., Rashid, M. H., Khan, M. B., Waters, M. F., Hess, D. C., Arbab, A. S., Vender, J. R., Hoda, N., Hoda, N., Hoda, N., Baban, B. & 3 others, Baban, B., Baban, B. & Dhandapani, K. M., May 2020, In: Science Advances. 6, 22, EAAX8847.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Traps
  • Traumatic Brain Injury
  • Deoxyribonuclease I
  • dornase alfa
  • Protein-Arginine Deiminases
  4 Scopus citations

• Preconditioning and cell-based therapeutics

  Hess, D. C. & Hoda, MD. N., Jan 1 2015, Cell Therapy for Brain Injury. Springer International Publishing, p. 173-186 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Stem cells
  • Stem Cells
  • Tissue
  • Minocycline
  • Blood pressure

• Recent advances in basic and translational stroke research

  Boltze, J., Kranz, A., Wagner, D. C., Reymann, K., Reiser, G. & Hess, D. C., Feb 2011, In: Expert Review of Neurotherapeutics. 11, 2, p. 199-202 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Translational Medical Research
  • Neuroprotection
  • Stroke
  • Cell- and Tissue-Based Therapy
  • Regeneration
  5 Scopus citations

• Remote ischaemic conditioning-a new paradigm of self-protection in the brain

  Hess, D. C., Blauenfeldt, R. A., Andersen, G., Hougaard, K. D., Hoda, M. N., Ding, Y. & Ji, X., Dec 1 2015, In: Nature Reviews Neurology. 11, 12, p. 698-710 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Conditioning (Psychology)
  • Brain
  • Intracranial Arteriosclerosis
  • Stroke
  • Clinical Trials
  75 Scopus citations

• Remote limb preconditioning and postconditioning: Will it translate into a promising treatment for acute stroke?

  Hess, D. C., Hoda, M. N. & Bhatia, K., Apr 2013, In: Stroke. 44, 4, p. 1191-1197 7 p.

  Research output: Contribution to journal › Review article › peer-review
  62 Scopus citations

• Response to letter by Lee regarding article, matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute stroke

  Switzer, J. A., Hess, D. C., Ergul, A. & Fagan, S. C., Oct 2011, In: Stroke. 42, 10, p. e567

  Research output: Contribution to journal › Letter › peer-review

• Response to letter regarding article, "Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type"

  Hoda, M. N., Hess, D. C., Ergul, A. & Fagan, S. C., Apr 2013, In: Stroke. 44, 4, p. e37

  Research output: Contribution to journal › Letter › peer-review
  2 Scopus citations

• Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial

  Hess, D. C., Wechsler, L. R., Clark, W. M., Savitz, S. I., Ford, G. A., Chiu, D., Yavagal, D. R., Uchino, K., Liebeskind, D. S., Auchus, A. P., Sen, S., Sila, C. A., Vest, J. D. & Mays, R. W., May 2017, In: The Lancet Neurology. 16, 5, p. 360-368 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Stem Cells
  • Placebos
  • Stroke
  • Safety
  • National Institutes of Health (U.S.)
  122 Scopus citations

• Serendipitous recanalization of basilar artery occlusion

  Switzer, J. A., Forseen, S. E., Bruno, A. & Hess, D. C., Nov 2013, In: Journal of Stroke and Cerebrovascular Diseases. 22, 8, p. e671-e673

  Research output: Contribution to journal › Article › peer-review

  • Tenecteplase
  • Basilar Artery
  • Angiography
  • Tomography
  • Dysarthria

• Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke

  Hoda, M. N., Li, W., Ahmad, A., Ogbi, S., Zemskova, M. A., Johnson, M. H., Ergul, A., Hill, W. D., Hess, D. C. & Sazonova, I. Y., Dec 16 2011, In: Experimental and Translational Stroke Medicine. 3, 1, 16.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Neuroprotection
  • Stroke
  • Matrix Metalloproteinases
  • Ovariectomy
  44 Scopus citations

• Short-Term Acute Exercise Preconditioning Reduces Neurovascular Injury After Stroke Through Induced eNOS Activation

  Hafez, S., Khan, M. B., Awad, M. E., Wagner, J. D. & Hess, D. C., Aug 1 2020, In: Translational Stroke Research. 11, 4, p. 851-860 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Exercise
  • Wounds and Injuries
  • Neuroprotection
  • N(G)-iminoethylornithine
  3 Scopus citations

• Simplified modified rankin scale questionnaire: Reproducibility over the telephone and validation with quality of life

  Bruno, A., Akinwuntan, A. E., Lin, C., Close, B., Davis, K., Baute, V., Aryal, T., Brooks, D., Hess, D. C., Switzer, J. A. & Nichols, F. T., Aug 2011, In: Stroke. 42, 8, p. 2276-2279 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Telephone
  • Quality of Life
  • Stroke
  • Neurology
  • Reproducibility of Results
  133 Scopus citations

• Simplified modified Rankin Scale questionnaire correlates with stroke severity

  Bruno, A., Close, B., Switzer, J. A., Hess, D. C., Gross, H., Nichols, F. T. & Akinwuntan, A. E., Aug 1 2013, In: Clinical Rehabilitation. 27, 8, p. 724-727 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • National Institutes of Health (U.S.)
  • Registries
  • Community Hospital
  • Hospital Departments
  14 Scopus citations

• Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II

  Savitz, S. I., Chopp, M., Deans, R., Carmichael, S. T., Phinney, D., Wechsler, L., Aronowski, J., Bednar, M., Boltze, J., Borlongan, C., Chase, T., Corbett, D., Cox, C. S., Cramer, S., Fischkoff, S., Frank, J., Greenberg, D., Hess, D., Hong, K., Koga, M. & 15 others, Jones, T., Keating, A., Kokaia, Z., Mays, R., Mora, K., Pittenger, M., Sanberg, P., Schallert, T., Sinden, J., Snyder, E., Steinberg, G., Victor, S., Willing, A., Yankee, E. & Yavagal, D., Mar 1 2011, In: Stroke. 42, 3, p. 825-829 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell- and Tissue-Based Therapy
  • Stem Cells
  • Stroke
  • Industry
  • National Institutes of Health (U.S.)
  188 Scopus citations

• Stroke telepresence: Removing all geographic barriers

  Hess, D. C. & Switzer, J. A., Mar 29 2011, In: Neurology. 76, 13, p. 1121-1123 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  10 Scopus citations

• Stroke treatment academic industry roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies

  Albers, G. W., Goldstein, L. B., Hess, D. C., Wechsler, L. R., Furie, K. L., Gorelick, P. B., Hurn, P., Liebeskind, D. S., Nogueira, R. G. & Saver, J. L., Sep 2011, In: Stroke. 42, 9, p. 2645-2650 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Industry
  • Stroke
  • Reperfusion
  • Therapeutics
  • Thrombolytic Therapy
  138 Scopus citations

• Telemedicine quality and outcomes in stroke: A scientific statement for healthcare professionals from the American Heart Association/American Stroke Association

  Wechsler, L. R., Demaerschalk, B. M., Schwamm, L. H., Adeoye, O. M., Audebert, H. J., Fanale, C. V., Hess, D. C., Majersik, J. J., Nystrom, K. V., Reeves, M. J., Rosamond, W. D. & Switzer, J. A., Jan 1 2017, In: Stroke. 48, 1, p. e3-e25

  Research output: Contribution to journal › Article › peer-review

  • Telemedicine
  • American Heart Association
  • Committee Membership
  • Stroke
  • Delivery of Health Care
  106 Scopus citations

• Teleneurology applications: Report of the telemedicine work group of the American Academy of Neurology

  Wechsler, L. R., Tsao, J. W., Levine, S. R., Swain-Eng, R. J., Adams, R. J., Demaerschalk, B. M., Hess, D. C., Moro, E., Schwamm, L. H., Steffensen, S., Stern, B. J., Zuckerman, S. J., Bhattacharya, P., Davis, L. E., Yurkiewicz, I. R. & Alphonso, A. L., Feb 12 2013, In: Neurology. 80, 7, p. 670-676 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Telemedicine
  • Neurology
  • Neurologists
  • Nervous System
  • Military Medicine
  91 Scopus citations

• Telestroke: Variations in intravenous thrombolysis by spoke hospitals

  Switzer, J. A., Singh, R., Mathiassen, L., Waller, J. L., Adams, R. J. & Hess, D. C., 2015, In: Journal of Stroke and Cerebrovascular Diseases. 24, 4, p. 739-744 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Tissue Plasminogen Activator
  • Stroke
  • Hospital Emergency Service
  • Nurses
  • Health Facility Size
  4 Scopus citations

• The Association Between Stroke Mortality and Time of Admission and Participation in a Telestroke Network

  Witrick, B., Zhang, D., Switzer, J. A., Hess, D. C. & Shi, L., Feb 2020, In: Journal of Stroke and Cerebrovascular Diseases. 29, 2, 104480.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Mortality
  • Hospital Mortality
  • Hospital Bed Capacity
  • Registries
  3 Scopus citations

• The history and future of telestroke

  Hess, D. C. & Audebert, H. J., Jun 2013, In: Nature Reviews Neurology. 9, 6, p. 340-350 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • History
  • Stroke
  • Patient Care
  • Telecommunications
  • Rural Hospitals
  41 Scopus citations

• Timeliness of intravenous thrombolysis via telestroke in Georgia

  Bruno, A., Lanning, K. M., Gross, H., Hess, D. C., Nichols, F. T. & Switzer, J. A., Sep 2013, In: Stroke. 44, 9, p. 2620-2622 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Hospital Emergency Service
  • Stroke
  • Communication
  • Referral and Consultation
  • Head
  11 Scopus citations

• Treatment of fever after stroke: Conflicting evidence

  Wrotek, S. E., Kozak, W. E., Hess, D. C. & Fagan, S. C., Nov 2011, In: Pharmacotherapy. 31, 11, p. 1085-1091 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Fever
  • Stroke
  • Body Temperature
  • Patient Harm
  • Antipyretics
  28 Scopus citations

• Use of telemedicine and helicopter transport to improve stroke care in remote locations

  Saler, M., Switzer, J. A. & Hess, D. C., Jun 2011, In: Current Treatment Options in Cardiovascular Medicine. 13, 3, p. 215-224 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Aircraft
  • Telemedicine
  • Stroke
  • X Ray Tomography
  • Ships
  17 Scopus citations

• Wisdom and determination in the ongoing pursuit of the ever-elusive neuroprotective agent

  Howard, G., Hess, D. C. & Howard, V. J., Jun 2011, In: Stroke. 42, 6, p. 1505-1506 2 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations