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  Activation-induced apoptosis in human macrophages: Developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon γ

  Munn, D. H., Beall, A. C., Song, D., Wrenn, R. W. & Throckmorton, D. C., Jan 1 1995, In: Journal of Experimental Medicine. 181, 1, p. 127-136 10 p.

  Research output: Contribution to journal › Article › peer-review
  170 Scopus citations

• Activation-induced elimination of peripheral t cells by mcsf-derived macrophages (M08)

  Mann, D. H., Attwood, J. T. & Mellor, A. L., Dec 1 1996, In: FASEB Journal. 10, 6, p. A1458

  Research output: Contribution to journal › Article › peer-review

• Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population

  Korkaya, H., Kim, G. I., Davis, A., Malik, F., Henry, N. L., Ithimakin, S., Quraishi, A. A., Tawakkol, N., D'Angelo, R., Paulson, A. K., Chung, S., Luther, T., Paholak, H. J., Liu, S., Hassan, K. A., Zen, Q., Clouthier, S. G. & Wicha, M. S., Aug 24 2012, In: Molecular Cell. 47, 4, p. 570-584 15 p.

  Research output: Contribution to journal › Article › peer-review
  358 Scopus citations

• Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B

  Shi, L., Chen, G., Macdonald, G., Bergeron, L., Li, H., Miura, M., Rotello, R. J., Miller, D. K., Li, P., Seshadri, T., Yuan, J. & Greenberg, A. H., Oct 1 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 20, p. 11002-11007 6 p.

  Research output: Contribution to journal › Article › peer-review
  75 Scopus citations

• Activation of apoptosis signaling eliminates CD34 ⁺ progenitor cells in blast crisis CML independent of response to tyrosine kinase inhibitors

  Mak, D. H., Wang, R. Y., Schober, W. D., Konopleva, M., Cortes, J., Kantarjian, H., Andreeff, M. & Carter, B. Z., Apr 2012, In: Leukemia. 26, 4, p. 788-794 7 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Activation of a protease cascade involved in patterning the Drosophila embryo

  LeMosy, E. K., Tan, Y. Q. & Hashimoto, C., Apr 24 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 9, p. 5055-5060 6 p.

  Research output: Contribution to journal › Article › peer-review
  74 Scopus citations

• Activation of Astrocytes in the Dorsomedial Striatum Facilitates Transition From Habitual to Goal-Directed Reward-Seeking Behavior

  Kang, S., Hong, S-I., Lee, J., Peyton, L., Baker, M., Choi, S., Kim, H., Chang, S-Y. & Choi, D-S., Nov 2020, In: Biological Psychiatry.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Activation of ATP-sensitive K⁺ channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes

  Lu, T., Hoshi, T., Weintraub, N. L., Spector, A. A. & Lee, H. C., Dec 15 2001, In: Journal of Physiology. 537, 3, p. 811-827 17 p.

  Research output: Contribution to journal › Article › peer-review
  70 Scopus citations

• Activation of BNIP3-mediated mitophagy protects against renal ischemia–reperfusion injury

  Tang, C., Han, H., Liu, Z., Liu, Y., Yin, L., Cai, J., He, L., Liu, Y., Chen, G., Zhang, Z., Yin, X. M. & Dong, Z., Sep 1 2019, In: Cell Death and Disease. 10, 9, 677.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  46 Scopus citations

• Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells

  Cavanagh, L. L., Bonasio, R., Mazo, I. B., Halin, C., Cheng, G., van der Velden, A. W. M., Cariappa, A., Chase, C., Russell, P., Starnbach, M. N., Koni, P. A., Pillai, S., Weninger, W. & von Andrian, U. H., Oct 2005, In: Nature Immunology. 6, 10, p. 1029-1037 9 p.

  Research output: Contribution to journal › Article › peer-review
  175 Scopus citations

• Activation of calpain, cathepsin-b and caspase-3 during transient focal cerebral ischemia in rat model

  Chaitanya, G. V. & Babu, P. P., Nov 2008, In: Neurochemical Research. 33, 11, p. 2178-2186 9 p.

  Research output: Contribution to journal › Article › peer-review
  43 Scopus citations

• Activation of calpain-2 by mediators in pulmonary vascular remodeling of pulmonary arterial hypertension

  Kovacs, L., Han, W., Rafikov, R., Bagi, Z., Offermanns, S., Saido, T. C., Black, S. M. & Su, Y., Mar 2016, In: American journal of respiratory cell and molecular biology. 54, 3, p. 384-393 10 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Activation of calpain by renin-angiotensin system in pleural mesothelial cells mediates tuberculous pleural fibrosis

  Yang, J., Xiang, F., Cai, P. C., Lu, Y. Z., Xu, X. X., Yu, F., Li, F. Z., Greer, P. A., Shi, H. Z., Zhou, Q., Xin, J. B., Ye, H., Su, Y. & Ma, W. L., Jul 1 2016, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 311, 1, p. L145-L153

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Activation of cAMP-dependent protein kinase is required for heterologous desensitization of adenylyl cyclase in S49 wild-type lymphoma cells.

  Clark, R. B., Kunkel, M. W., Friedman, J., Goka, T. J. & Johnson, J. A., Mar 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 5, p. 1442-1446 5 p.

  Research output: Contribution to journal › Article › peer-review
  104 Scopus citations

• Activation of caspase-2 in apoptosis

  Li, H., Bergeron, L., Cryns, V., Pasternack, M. S., Zhu, H., Shi, L., Greenberg, A. & Yuan, J., Aug 22 1997, In: Journal of Biological Chemistry. 272, 34, p. 21010-21017 8 p.

  Research output: Contribution to journal › Article › peer-review
  166 Scopus citations

• Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor

  Eldredge, E. R., Korf, G. M., Christensen, T. A., Connolly, D. C., Getz, M. J. & Maihle, N. J., Nov 1994, In: Molecular and Cellular Biology. 14, 11, p. 7527-7534 8 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• Activation of cGMP-dependent protein kinase by protein kinase C

  Hou, Y., Lascola, J., Dulin, N. O., Ye, R. D. & Browning, D. D., May 9 2003, In: Journal of Biological Chemistry. 278, 19, p. 16706-16712 7 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Activation of c-Jun NH₂-terminal kinase 3 is mediated by the GluR6·PSD-95·MLK3 signaling module following cerebral ischemia in rat hippocampus

  Tian, H., Zhang, Q. G., Zhu, G. X., Pei, D. S., Guan, Q. H. & Zhang, G. Y., Nov 2 2005, In: Brain Research. 1061, 1, p. 57-66 10 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation

  Kevin Leach, J., Black, S. M., Schmidt-Ullrich, R. K. & Mikkelsen, R. B., May 3 2002, In: Journal of Biological Chemistry. 277, 18, p. 15400-15406 7 p.

  Research output: Contribution to journal › Article › peer-review
  113 Scopus citations

• Activation of cryptic metabolite production through gene disruption: Dimethyl furan-2,4-dicarboxylate produced by Streptomyces sahachiroi

  Simkhada, D., Zhang, H., Mori, S., Williams, H. & Watanabe, C. M. H., Aug 29 2013, In: Beilstein Journal of Organic Chemistry. 9, p. 1768-1773 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Scopus citations

• Activation of diverse signaling pathways by Ex-vivo delivery of multiple cytokines for myocardial repair

  Konoplyannikov, M., Haider, K. H., Lai, V. K., Ahmed, R. P. H., Jiang, S. & Ashraf, M., Jan 15 2013, In: Stem Cells and Development. 22, 2, p. 204-215 12 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Activation of endoplasmic reticulum stress response following trauma-hemorrhage

  Jian, B., Hsieh, C. H., Chen, J., Choudhry, M., Bland, K., Chaudry, I. & Raju, R., Nov 2008, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1782, 11, p. 621-626 6 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and l-citrulline formation

  Schmidt, K., Martens-Lobenhoffer, J., Meinitzer, A., Graier, W. F., Torres, C. M., Venema, R. C. & Mayer, B., May 15 2010, In: Nitric Oxide - Biology and Chemistry. 22, 4, p. 281-289 9 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Activation of ERK5 is mediated by N-methyl-D-aspartate receptor and L-type voltage-gated calcium channel via Src involving oxidative stress after cerebral ischemia in rat hippocampus

  Wang, R. M., Zhang, Q. G. & Zhang, G. Y., Feb 26 2004, In: Neuroscience Letters. 357, 1, p. 13-16 4 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Activation of extracellular signal-regulated kinase 5 may play a neuroprotective role in hippocampal CA3/DG region after cerebral ischemia

  Wang, R. M., Zhang, Q., Li, C. H. & Zhang, G. Y., May 1 2005, In: Journal of Neuroscience Research. 80, 3, p. 391-399 9 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains

  Hossain, M. A., Shen, Y., Knudson, I., Thakur, S., Stees, J. R., Qiu, Y., Pace, B. S., Peterson, K. R. & Bungert, J., 2016, In: Molecular Therapy - Nucleic Acids. 5, p. e378

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion

  Zhang, F., Li, C., Wang, R., Han, D., Zhang, Q. G., Zhou, C., Yu, H. M. & Zhang, G. Y., Dec 19 2007, In: Neuroscience. 150, 4, p. 938-949 12 p.

  Research output: Contribution to journal › Article › peer-review
  72 Scopus citations

• Activation of gelatinolytic/collagenolytic activity in dentin by self-etching adhesives

  Nishitani, Y., Yoshiyama, M., Wadgaonkar, B., Breschi, L., Mannello, F., Mazzoni, A., Carvalho, R. M., Tjäderhane, L., Tay, F. R. & Pashley, D. H., Apr 2006, In: European Journal of Oral Sciences. 114, 2, p. 160-166 7 p.

  Research output: Contribution to journal › Article › peer-review
  282 Scopus citations

• Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

  Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., Lee, J. R., Offermanns, S. & Ganapathy, V., Jan 16 2014, In: Immunity. 40, 1, p. 128-139 12 p.

  Research output: Contribution to journal › Article › peer-review
  1020 Scopus citations

• Activation of G protein-coupled estrogen receptor induces endotheliumindependent relaxation of coronary artery smooth muscle

  Yu, X., Ma, H., Barman, S. A., Liu, A. T., Sellers, M., Stallone, J. N., Prossnitz, E. R., White, R. E. & Han, G., Nov 2011, In: American Journal of Physiology - Endocrinology and Metabolism. 301, 5, p. E882-E888

  Research output: Contribution to journal › Article › peer-review
  69 Scopus citations

• Activation of hexosamine pathway impairs nitric oxide (NO)-dependent arteriolar dilations by increased protein O-GlcNAcylation

  Beleznai, T. & Bagi, Z., Mar 2012, In: Vascular Pharmacology. 56, 3-4, p. 115-121 7 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• Activation of IL-11/STAT3 pathway in preconditioned human skeletal myoblasts blocks apoptotic cascade under oxidant stress

  Idris, N. M., Ashraf, M., Ahmed, R. P. H., Shujia, J. & Haider, K. H., Jan 2012, In: Regenerative Medicine. 7, 1, p. 47-57 11 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing

  Boini, K. M., Xia, M., Abais, J. M., Li, G., Pitzer, A. L., Gehr, T. W. B., Zhang, Y. & Li, P. L., May 2014, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 5, p. 836-845 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  59 Scopus citations

• Activation of mesangial cell MAPK in response to homocysteine

  Ingram, A. J., Krepinsky, J. C., James, L., Austin, R. C., Tang, D., Salapatek, A. M., Thai, K. & Scholey, J. W., Aug 2004, In: Kidney International. 66, 2, p. 733-745 13 p.

  Research output: Contribution to journal › Article › peer-review
  42 Scopus citations

• Activation of midbrain structures by associative novelty and the formation of explicit memory in humans

  Schott, B. H., Sellner, D. B., Lauer, C. J., Habib, R., Frey, J. U., Guderian, S., Heinze, H. J. & Düzel, E., Jul 2004, In: Learning and Memory. 11, 4, p. 383-387 5 p.

  Research output: Contribution to journal › Article › peer-review
  100 Scopus citations

• Activation of mitochondrial ATP-sensitive K⁺ channel for cardiac protection against ischemic injury is dependent on protein kinase C activity

  Wang, Y., Hirai, K. & Ashraf, M., Oct 15 1999, In: Circulation research. 85, 8, p. 731-741 11 p.

  Research output: Contribution to journal › Article › peer-review
  179 Scopus citations

• Activation of mitochondrial K(ATP) channel elicits late preconditioning against myocardial infarction via protein kinase C signaling pathway

  Takashi, E., Wang, Y. & Ashraf, M., Dec 3 1999, In: Circulation research. 85, 12, p. 1146-1153 8 p.

  Research output: Contribution to journal › Article › peer-review
  151 Scopus citations

• Activation of muscarinic acetylcholine receptors enhances the release of endogenous cannabinoids in the hippocampus

  Kim, J., Isokawa, M., Ledent, C. & Alger, B. E., Dec 1 2002, In: Journal of Neuroscience. 22, 23, p. 10182-10191 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  253 Scopus citations

• Activation of myeloid TLR4 Mediates T lymphocyte polarization after traumatic brain injury

  Braun, M., Vaibhav, K., Saad, N., Fatima, S., Brann, D. W., Vender, J. R., Wang, L., Hoda, MD. N., Baban, B. & Dhandapani, K. M., May 1 2017, In: Journal of Immunology. 198, 9, p. 3615-3626 12 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• Activation of NAD(P)H oxidase by lipid hydroperoxides: Mechanism of oxidant-mediated smooth muscle cytotoxicity

  Li, W. G., Stoll, L. L., Rice, J. B., Xu, S. P., Miller, F. J., Chatterjee, P., Hu, L., Oberley, L. W., Spector, A. A. & Weintraub, N. L., Apr 1 2003, In: Free Radical Biology and Medicine. 34, 7, p. 937-946 10 p.

  Research output: Contribution to journal › Article › peer-review
  46 Scopus citations

• Activation of NF-κB by bradykinin through a Gα(q)- and Gβγ-dependent pathway that involves phosphoinositide 3-kinase and Akt

  Xie, P., Browning, D. D., Hay, N., Mackman, N. & Ye, R. D., Aug 11 2000, In: Journal of Biological Chemistry. 275, 32, p. 24907-24914 8 p.

  Research output: Contribution to journal › Article › peer-review
  120 Scopus citations

• Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia

  Zhang, C., Boini, K. M., Xia, M., Abais, J. M., Li, X., Liu, Q. & Li, P. L., Jul 2012, In: Hypertension. 60, 1, p. 154-162 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  135 Scopus citations

• Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors

  Gaisina, I. N., Lee, S. H., Kaidery, N. A., Ben Aissa, M., Ahuja, M., Smirnova, N. N., Wakade, S., Gaisin, A., Bourassa, M. W., Ratan, R. R., Nikulin, S. V., Poloznikov, A. A., Thomas, B., Thatcher, G. R. J. & Gazaryan, I. G., May 16 2018, In: ACS Chemical Neuroscience. 9, 5, p. 894-900 7 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice

  Kimbler, D. E., Shields, J., Yanasak, N., Vender, J. R. & Dhandapani, K. M., Jul 17 2012, In: PloS one. 7, 7, e41229.

  Research output: Contribution to journal › Article › peer-review
  106 Scopus citations

• Activation of p38 mitogen-activated protein kinase by lipopolysaccharide in human neutrophils requires nitric oxide-dependent cGMP accumulation

  Browning, D. D., Windes, N. D. & Ye, R. D., Jan 1 1999, In: Journal of Biological Chemistry. 274, 1, p. 537-542 6 p.

  Research output: Contribution to journal › Article › peer-review
  56 Scopus citations

• Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c⁺CD103⁺ Monocytic Antigen-Presenting Cells in Tumors

  Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In: Immunity. 48, 1, p. 91-106.e6

  Research output: Contribution to journal › Article › peer-review
  53 Scopus citations

• Activation of particulate guanylyl cyclase by endothelins in cultured SV-40 transformed cat iris sphincter smooth muscle cells

  Ding, K. H., Latimer, A. J. & Abdel-Latif, A. A., Dec 11 1998, In: Life sciences. 64, 3, p. 161-174 14 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Activation of PERK elicits memory impairment through inactivation of CREB and downregulation of PSD95 after traumatic brain injury

  Sen, T., Gupta, R., Kaiser, H. & Sen, N., Jun 14 2017, In: Journal of Neuroscience. 37, 24, p. 5900-5911 12 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Activation of peroxisome proliferator-activated receptor α by substituted urea-derived soluble epoxide hydrolase inhibitors

  Fang, X., Hu, S., Watanabe, T., Weintraub, N. L., Snyder, G. D., Yao, J., Liu, Y., Shyy, J. Y. J., Hammock, B. D. & Spector, A. A., Jul 2005, In: Journal of Pharmacology and Experimental Therapeutics. 314, 1, p. 260-270 11 p.

  Research output: Contribution to journal › Article › peer-review
  60 Scopus citations

• Activation of platelet-derived growth factor (PDGF) receptor-operated Ca²⁺ channel via tyrosine kinase and ras in mesangial cells

  Ma, H., Matsunaga, H., Li, B., Marrero, M. B., Eaton, D. C. & Ling, B. N., 1996, In: FASEB Journal. 10, 3, p. A139

  Research output: Contribution to journal › Article › peer-review