Find Research outputs — Augusta University Research Profiles

Article

A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies

Peterson, K. R., Costa, F. C., Fedosyuk, H., Neades, R. Y., Chazelle, A. M., Zelenchuk, L., Fonteles, A. H., Dalal, P., Roy, A., Chaguturu, R., Li, B. & Pace, B. S., Sep 16 2014, In: PloS one. 9, 9, e107006.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease

Pace, B. S., Liu, L., Li, B. & Makala, L. H., Aug 19 2015, In: Experimental Biology and Medicine. 240, 8, p. 1050-1064 15 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation

Li, B., Ding, L., Li, W., Story, M. D. & Pace, B. S., Apr 26 2012, In: BMC Genomics. 13, 1, 153.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Characterization of transcription factor networks involved in umbilical cord blood CD34⁺ stem cells-derived erythropoiesis

Li, B., Ding, L., Yang, C., Kang, B., Liu, L., Story, M. D. & Pace, B. S., Sep 2014, In: PloS one. 9, 9, e0107133.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice

Oseghale, A. R., Zhu, X., Li, B., Peterson, K. R., Nudelman, A., Rephaeli, A., Xu, H. & Pace, B. S., Nov 2019, In: Blood Cells, Molecules, and Diseases. 79, 102345.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease

Li, B., Zhu, X., Ward, C. M., Starlard-Davenport, A., Takezaki, M., Berry, A., Ward, A., Wilder, C., Neunert, C., Kutlar, A. & Pace, B. S., Feb 2019, In: Experimental Hematology. 70, p. 85-96.e5

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

MIR29B mediates epigenetic mechanisms of HBG gene activation

Starlard-Davenport, A., Smith, A., Vu, L., Li, B. & Pace, B. S., Jul 2019, In: British Journal of Haematology. 186, 1, p. 91-100 10 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina.

Promsote, W., Makala, L., Li, B., Smith, S. B., Singh, N., Ganapathy, V., Pace, B. S. & Martin, P. M., Aug 2014, In: Investigative ophthalmology & visual science. 55, 8, p. 5382-5393 12 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Novel inducers of fetal globin identified through high throughput screening (HTS) are active in vivo in anemic baboons and transgenic mice

Boosalis, M. S., Sangerman, J. I., White, G. L., Wolf, R. F., Shen, L., Dai, Y., White, E., Makala, L. H., Li, B., Pace, B. S., Nouraie, M., Faller, D. V. & Perrine, S. P., Dec 1 2015, In: PloS one. 10, 12, 0144660.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Original Research: Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells

Ward, C. M., Li, B. & Pace, B. S., Apr 2016, In: Experimental Biology and Medicine. 241, 7, p. 719-729 11 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Chapter

Personalized chemotherapy of tumor disease based on system modeling

Li, B., 2016, Frontiers in Drug Design and Discovery. 1 ed. Bentham Science Publishers B.V., p. 223-247 25 p. (Frontiers in Drug Design and Discovery; vol. 7, no. 1).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Single-cell next-generation sequencing and its applications in cancer biology

Li, B., Zhang, X. & Zheng, J., Jan 1 2015, Next Generation Sequencing in Cancer Research, Volume 2: From Basepairs to Bedsides. Springer International Publishing, p. 1-18 18 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter