Find Research outputs

Search results

• 2021

  Kynurenine induces an age-related phenotype in bone marrow stromal cells

  Patel, D., Potter, M., Anaya, J. M., McGee-Lawrence, M. E., Hamrick, M. W., Hill, W. D., Isales, C. M. & Fulzele, S. T., Apr 2021, In: Mechanisms of Ageing and Development. 195, 111464.

  Research output: Contribution to journal › Review article › peer-review

  • Kynurenine
  • Mesenchymal Stem Cells
  • Phenotype
  • Tryptophan
  • Indoleamine-Pyrrole 2,3,-Dioxygenase

• MicroRNAs are critical regulators of senescence and aging in mesenchymal stem cells

  Potter, M. L., Hill, W. D., Isales, C. M., Hamrick, M. W. & Fulzele, S., Jan 2021, In: Bone. 142, 115679.

  Research output: Contribution to journal › Article › peer-review

  • Mesenchymal Stem Cells
  • MicroRNAs
  • Cellular Senescence
  • Musculoskeletal Diseases
  • Regenerative Medicine
  1 Scopus citations
• 2020

  Accumulation of kynurenine elevates oxidative stress and alters microRNA profile in human bone marrow stromal cells

  Dalton, S., Smith, K., Singh, K., Kaiser, H., Kolhe, R., Mondal, A. K., Khayrullin, A., Isales, C. M., Hamrick, M. W., Hill, W. D. & Fulzele, S., Feb 2020, In: Experimental Gerontology. 130, 110800.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Kynurenine
  • Bone
  • Mesenchymal Stem Cells
  • MicroRNAs
  6 Scopus citations

• Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells

  Elmansi, A. M., Hussein, K. A., Herrero, S. M., Periyasamy-Thandavan, S., Aguilar-Pérez, A., Kondrikova, G., Kondrikov, D., Eisa, N. H., Pierce, J. L., Kaiser, H., Ding, K. H., Walker, A. L., Jiang, X., Bollag, W. B., Elsalanty, M., Zhong, Q., Shi, X. M., Su, Y., Johnson, M., Hunter, M. & 7 others, Reitman, C., Volkman, B. F., Hamrick, M. W., Isales, C. M., Fulzele, S., McGee-Lawrence, M. E. & Hill, W. D., Jun 2020, In: Bone Reports. 12, 100270.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • histone deacetylase 3
  • Kynurenine
  • Mesenchymal Stem Cells
  • Epigenomics
  • Enzymes
  4 Scopus citations

• COVID-19 virulence in aged patients might be impacted by the host cellular MicroRNAs abundance/profile

  Fulzele, S., Sahay, B., Yusufu, I., Lee, T. J., Sharma, A., Kolhe, R. & Isales, C. M., May 1 2020, In: Aging and Disease. 11, 3, p. 509-522 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus
  • Virulence
  • MicroRNAs
  • Genome
  • Viral Genome
  20 Scopus citations

• Decreased pericellular matrix production and selection for enhanced cell membrane repair may impair osteocyte responses to mechanical loading in the aging skeleton

  Hagan, M. L., Yu, K., Zhu, J., Vinson, B. N., Roberts, R. L., Montesinos Cartagena, M., Johnson, M. H., Wang, L., Isales, C. M., Hamrick, M. W., McNeil, P. L. & McGee-Lawrence, M. E., Jan 1 2020, In: Aging Cell. 19, 1, e13056.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteocytes
  • Skeleton
  • Cell Membrane
  • Oxidative Stress
  • Bone and Bones
  6 Scopus citations

• Deletion of PPARγin Mesenchymal Lineage Cells Protects Against Aging-Induced Cortical Bone Loss in Mice

  Cao, J., Ding, K., Pan, G., Rosario, R., Su, Y., Bao, Y., Zhou, H., Xu, J., McGee Lawrence, M. E., Hamrick, M. W., Isales, C. M. & Shi, X., Apr 17 2020, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 75, 5, p. 826-834 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cortical Bone
  • PPAR gamma
  • Bone and Bones
  • Interferons
  • Inflammation
  1 Scopus citations

• Kynurenine inhibits autophagy and promotes senescence in aged bone marrow mesenchymal stem cells through the aryl hydrocarbon receptor pathway

  Kondrikov, D., Elmansi, A., Bragg, R. T., Mobley, T., Barrett, T., Eisa, N., Kondrikova, G., Schoeinlein, P., Aguilar-Perez, A., Shi, X. M., Fulzele, S., Lawrence, M. M. G., Hamrick, M., Isales, C. & Hill, W., Feb 2020, In: Experimental Gerontology. 130, 110805.

  Research output: Contribution to journal › Article › peer-review

  • Stem cells
  • Kynurenine
  • Aryl Hydrocarbon Receptors
  • Autophagy
  • Bone
  15 Scopus citations

• Kynurenine promotes rankl–induced osteoclastogenesis in vitro by activating the aryl hydrocarbon receptor pathway

  Eisa, N. H., Reddy, S. V., Elmansi, A. M., Kondrikova, G., Kondrikov, D., Shi, X. M., Novince, C. M., Hamrick, M. W., McGee-Lawrence, M. E., Isales, C. M., Fulzele, S. & Hill, W. D., Nov 1 2020, In: International journal of molecular sciences. 21, 21, p. 1-16 16 p., 7931.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteoclasts
  • kynurenine receptor
  • Kynurenine
  • Aryl Hydrocarbon Receptors
  • hydrocarbons

• Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo

  Pierce, J. L., Roberts, R. L., Yu, K., Kendall, R. K., Kaiser, H., Davis, C., Johnson, M. H., Hill, W. D., Isales, C. M., Bollag, W. B., Hamrick, M. W. & McGee-Lawrence, M. E., Feb 2020, In: Experimental Gerontology. 130, 110818.

  Research output: Contribution to journal › Article › peer-review

  • Osteoblasts
  • Kynurenine
  • In Vitro Techniques
  • Energy Metabolism
  • Bone
  4 Scopus citations

• Picolinic acid, a tryptophan oxidation product, does not impact bone mineral density but increases marrow adiposity

  Ding, K., McGee-Lawrence, M. E., Kaiser, H., Sharma, A. K., Pierce, J. L., Irsik, D. L., Bollag, W. B., Xu, J., Zhong, Q., Hill, W., Shi, X. M., Fulzele, S., Kennedy, E. J., Elsalanty, M., Hamrick, M. W. & Isales, C. M., May 2020, In: Experimental Gerontology. 133, 110885.

  Research output: Contribution to journal › Article › peer-review

  • picolinic acid
  • Tryptophan
  • Adiposity
  • Minerals
  • Bone
  3 Scopus citations

• Role of dendritic cell-mediated immune response in oral homeostasis: A new mechanism of osteonecrosis of the jaw

  Elsayed, R., Kurago, Z., Cutler, C. W., Arce, R. M., Gerber, J., Celis, E., Sultan, H., Elashiry, M., Meghil, M., Sun, C., Auersvald, C. M., Awad, M. E., Zeitoun, R., Elsayed, R., Eldin M. Elshikh, M., Isales, C. & Elsalanty, M. E., Feb 1 2020, In: FASEB Journal. 34, 2, p. 2595-2608 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dendritic Cells
  • Osteonecrosis
  • Jaw
  • Zoledronic Acid
  • Homeostasis
  3 Scopus citations

• Sex-specific differences in extracellular vesicle protein cargo in synovial fluid of patients with osteoarthritis

  Kolhe, R., Owens, V., Sharma, A., Lee, T. J., Zhi, W., Ghilzai, U., Mondal, A. K., Liu, Y., Isales, C. M., Hamrick, M. W., Hunter, M. & Fulzele, S., Dec 2020, In: Life. 10, 12, p. 1-13 13 p., 337.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • synovial fluid
  • osteoarthritis
  • cargo
  • Extracellular Vesicles
  • Synovial Fluid

• Special issue: The kynurenine pathway in aging

  Hamrick, M. W. & Isales, C. M., Jun 2020, In: Experimental Gerontology. 134, 110895.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• The role of tryptophan metabolites in musculoskeletal stem cell aging

  Anaya, J. M., Bollag, W. B., Hamrick, M. W. & Isales, C. M., Sep 2 2020, In: International journal of molecular sciences. 21, 18, p. 1-13 13 p., 6670.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stem cells
  • stem cells
  • Metabolites
  • tryptophan
  • metabolites
• 2019

  Age-dependent oxidative stress elevates arginase 1 and uncoupled nitric oxide synthesis in skeletal muscle of aged mice

  Pandya, C. D., Lee, B., Toque, H. A., Mendhe, B., Bragg, R. T., Pandya, B., Atawia, R. T., Isales, C., Hamrick, M., Caldwell, R. W. & Fulzele, S., 2019, In: Oxidative medicine and cellular longevity. 2019, 1704650.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oxidative stress
  • Arginase
  • Muscle
  • Nitric Oxide
  • Skeletal Muscle
  5 Scopus citations

• Association of blood n-3 fatty acid with bone mass and bone marrow TRAP-5b in the elderly with and without hip fracture

  Kim, B. J., Yoo, H. J., Park, S. J., Kwak, M. K., Lee, S. H., Kim, S. J., Hamrick, M. W., Isales, C. M., Ahn, S. H. & Koh, J. M., May 1 2019, In: Osteoporosis International. 30, 5, p. 1071-1078 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Omega-3 Fatty Acids
  • Hip Fractures
  • Bone Marrow
  • Elderly
  • Bone and Bones
  1 Scopus citations

• Association of Dietary Niacin Intake With Incident Hip Fracture, BMD, and Body Composition: The Cardiovascular Health Study

  Carbone, L. D., Bůžková, P., Fink, H. A., Raiford, M., Le, B., Isales, C. M., Shikany, J. M., Coughlin, S. S. & Robbins, J. A., Apr 2019, In: Journal of Bone and Mineral Research. 34, 4, p. 643-652 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pelvic Bones
  • Niacin
  • Hip Fractures
  • Body Composition
  • Bone Density
  3 Scopus citations

• Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss

  Singleton, Q., Vaibhav, K., Braun, M., Patel, C., Khayrullin, A., Mendhe, B., Lee, B. R., Kolhe, R., Kaiser, H., Awad, M. E., Fariyike, T., Elsayed, R., Elsalanty, M., Isales, C. M., Liu, Y., Hamrick, M. W., Dhandapani, K. M. & Fulzele, S., Jan 2019, In: Fuel Cells. 8, 1

  Research output: Contribution to journal › Article › peer-review

  • Osteoclasts
  • Bone
  • Brain

• Elevated ceramides 18:0 and 24:1 with aging are associated with hip fracture risk through increased bone resorption

  Kim, B. J., Lee, J. Y., Park, S. J., Lee, S. H., Kim, S. J., Yoo, H. J., De Pena, S. I. R., McGee-Lawrence, M., Isales, C. M., Koh, J. M. & Hamrick, M. W., 2019, In: Aging. 11, 21, p. 9388-9404 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceramides
  • Hip Fractures
  • Bone Resorption
  • Bone Marrow
  • Osteogenesis
  2 Scopus citations

• Endogenous Glucocorticoid Signaling in the Regulation of Bone and Marrow Adiposity: Lessons from Metabolism and Cross Talk in Other Tissues

  Sharma, A. K., Shi, X., Isales, C. M. & McGee-Lawrence, M. E., Dec 1 2019, In: Current Osteoporosis Reports. 17, 6, p. 438-445 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Adiposity
  • Glucocorticoids
  • Glucocorticoid Receptors
  • Adipose Tissue
  • Bone Marrow
  1 Scopus citations

• Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation

  Kaiser, H., Yu, K., Pandya, C., Mendhe, B., Isales, C. M., McGee-Lawrence, M. E., Johnson, M., Fulzele, S. & Hamrick, M. W., 2019, In: Oxidative medicine and cellular longevity. 2019, 9894238.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metabolites
  • Kynurenine
  • Muscular Atrophy
  • Tryptophan
  • Lipid Peroxidation
  11 Scopus citations

• Lower hand grip strength in older adults with non-alcoholic fatty liver disease: A nationwide population-based study

  Kim, B. J., Ahn, S. H., Lee, S. H., Hong, S., Hamrick, M. W., Isales, C. M. & Koh, J. M., Jul 1 2019, In: Aging. 11, 13, p. 4547-4560 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Non-alcoholic Fatty Liver Disease
  • Hand Strength
  • Muscle Strength
  • Population
  • Korea
  9 Scopus citations

• Meta-analysis and evidence base for the efficacy of autologous bone marrow mesenchymal stem cells in knee cartilage repair: Methodological guidelines and quality assessment

  Awad, M. E., Hussein, K. A., Helwa, I., Abdelsamid, M. F., Aguilar-Perez, A., Mohsen, I., Hunter, M., Hamrick, M. W., Isales, C. M., Elsalanty, M., Hill, W. D. & Fulzele, S., 2019, In: Stem Cells International. 2019, 3826054.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mesenchymal Stem Cells
  • Cartilage
  • Knee
  • Meta-Analysis
  • Guidelines
  10 Scopus citations

• MicroRNA-141-3p Negatively Modulates SDF-1 Expression in Age-Dependent Pathophysiology of Human and Murine Bone Marrow Stromal Cells

  Periyasamy-Thandavan, S., Burke, J., Mendhe, B., Kondrikova, G., Kolhe, R., Hunter, M., Isales, C. M., Hamrick, M. W., Hill, W. D., Fulzele, S., Beerman, I. & Hare, J., Aug 16 2019, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 9, p. 1368-1374 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mesenchymal Stem Cells
  • MicroRNAs
  • Bone Marrow
  • Chemokine CXCL12
  • Small Untranslated RNA
  9 Scopus citations

• Monomethylfumarate protects against ovariectomy-related changes in body composition

  Bollag, A. E., Guo, T., Ding, K. H., Choudhary, V., Chen, X., Zhong, Q., Xu, J., Yu, K., Awad, M. E., Elsalanty, M., Johnson, M. H., McGee-Lawrence, M. E., Bollag, W. B. & Isales, C. M., Oct 2019, In: Journal of Endocrinology. 243, 1, p. 15-26 12 p.

  Research output: Contribution to journal › Article › peer-review

  • citraconic acid
  • Ovariectomy
  • Body Composition
  • RANK Ligand
  • Antioxidants
  1 Scopus citations

• Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells

  Fulzele, S. T., Mendhe, B., Khayrullin, A., Johnson, M. H., Kaiser, H., Liu, Y., Isales, C. M. & Hamrick, M. W., Mar 31 2019, In: Aging. 11, 6, p. 1791-1803 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Vesicles
  • Bone Marrow Cells
  • Stem Cells
  • Muscles
  • Mesenchymal Stem Cells
  28 Scopus citations

• Phosphatidylglycerol Inhibits Toll-Like Receptor–Mediated Inflammation by Danger-Associated Molecular Patterns

  Choudhary, V., Uaratanawong, R., Patel, R. R., Patel, H., Bao, W., Hartney, B., Cohen, E., Chen, X., Zhong, Q., Isales, C. M. & Bollag, W. B., Apr 2019, In: Journal of Investigative Dermatology. 139, 4, p. 868-877 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatidylglycerols
  • Keratinocytes
  • Psoriasis
  • Inflammation
  • Chemical activation
  10 Scopus citations

• Role of MicroRNA-141 in the Aging Musculoskeletal System: A Current Overview

  Fariyike, B., Singleton, Q., Hunter, M., Hill, W. D., Isales, C. M., Hamrick, M. W. & Fulzele, S., Mar 2019, In: Mechanisms of Ageing and Development. 178, p. 9-15 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Musculoskeletal System
  • MicroRNAs
  • Osteoarthritis
  • Osteoporosis
  • Osteogenesis
  9 Scopus citations

• Stromal cell-derived factor-1 (CXCL12) and its role in bone and muscle biology

  Gilbert, W., Bragg, R., Elmansi, A. M., McGee Lawrence, M. E., Isales, C. M., Hamrick, M. W., Hill, W. D. & Fulzele, S. T., Nov 2019, In: Cytokine. 123, 154783.

  Research output: Contribution to journal › Review article › peer-review

  • Stem cells
  • Chemokine CXCL12
  • Bone
  • Muscle
  • Osteoclasts
  3 Scopus citations

• Stromal cell-derived factor-1 as a potential therapeutic target for osteoarthritis and rheumatoid arthritis

  Bragg, R., Gilbert, W., Elmansi, A. M., Isales, C. M., Hamrick, M. W., Hill, W. D. & Fulzele, S., 2019, In: Therapeutic Advances in Chronic Disease. 10

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Chemokine CXCL12
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Cartilage
  • T140 peptide
  2 Scopus citations

• The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study

  Le, B., Bůžková, P., Robbins, J. A., Fink, H. A., Raiford, M., Isales, C. M., Shikany, J. M., Coughlin, S. S. & Carbone, L. D., Aug 15 2019, In: Calcified Tissue International. 105, 2, p. 161-172 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Aromatic Amino Acids
  • Hip Fractures
  • Body Composition
  • Bone Density
  • Health
  2 Scopus citations

• The detrimental effects of kynurenine, a tryptophan metabolite, on human bone metabolism

  Kim, B. J., Hamrick, M. W., Yoo, H. J., Lee, S. H., Kim, S. J., Koh, J. M. & Isales, C. M., Jun 1 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 6, p. 2334-2342 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metabolites
  • Kynurenine
  • Metabolism
  • Tryptophan
  • Bone
  20 Scopus citations

• The glucocorticoid receptor in osteoprogenitors regulates bone mass and marrow fat

  Pierce, J. L., Ding, K. H., Xu, J., Sharma, A. K., Yu, K., Arbona, N. M., Rodr guez-Santos, Z., Bernard, P. J., Bollag, W. B., Johnson, M. H., Hamrick, M. W., Begun, D. L., Shi, X. M., Isales, C. M. & McGee-Lawrence, M. E., Oct 2019, In: Journal of Endocrinology. 243, 1, p. 27-42 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Caloric Restriction
  • Glucocorticoid Receptors
  • Fats
  • Bone Marrow
  • Glucocorticoids
  3 Scopus citations

• What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands

  Elmansi, A. M., Awad, M. E., Eisa, N. H., Kondrikov, D., Hussein, K. A., Aguilar-Pérez, A., Herberg, S., Periyasamy-Thandavan, S., Fulzele, S., Hamrick, M. W., McGee-Lawrence, M. E., Isales, C. M., Volkman, B. F. & Hill, W. D., Jun 2019, In: Pharmacology and Therapeutics. 198, p. 90-108 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Dipeptidyl Peptidase 4
  • Peptide Hormones
  • Proteolysis
  • Ligands
  • Cytokines
  6 Scopus citations
• 2018

  Amino acids as signaling molecules modulating bone turnover

  Ding, K., Cain, M., Davis, M., Bergson, C. M., McGee Lawrence, M. E., Perkins, C., Hardigan, T., Shi, X. M., Zhong, Q., Xu, J., Bollag, W. B., Hill, W. D., Elsalanty, M. E., Hunter, D. M., Isales, M. C., Lopez, P., Hamrick, M. W. & Isales, C. M., Oct 2018, In: Bone. 115, p. 15-24 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bone Remodeling
  • Amino Acids
  • Protein-Restricted Diet
  • Aromatic Amino Acids
  • Mesenchymal Stem Cells
  11 Scopus citations

• Association of serum TSH with handgrip strength in community-dwelling euthyroid elderly

  Kim, B. J., Lee, S. H., Isales, C. M., Hamrick, M. W., Kwak, M. K. & Koh, J. M., 2018, In: Journal of Clinical Endocrinology and Metabolism. 103, 11, p. 3986-3992 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Independent Living
  • Muscle
  • Elderly
  • Muscle Strength
  • Muscle Strength Dynamometer
  6 Scopus citations

• Deletion of protein kinase D1 in osteoprogenitor cells results in decreased osteogenesis in vitro and reduced bone mineral density in vivo

  Bollag, W. B., Choudhary, V., Zhong, Q., Ding, K. H., Xu, J., Elsayed, R., Yu, K., Su, Y., Bailey, L. J., Shi, X. M., Elsalanty, M., Johnson, M. H., McGee-Lawrence, M. E. & Isales, C. M., Feb 5 2018, In: Molecular and Cellular Endocrinology. 461, p. 22-31 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Minerals
  • Bone
  • Protein Kinases
  • Bone Density
  • Osteogenesis
  4 Scopus citations

• Differentially expressed genes in PPARγ-deficient MSCs

  Su, Y., Shen, X., Chen, J., Isales, C. M., Zhao, J. & Shi, X. M., Aug 15 2018, In: Molecular and Cellular Endocrinology. 471, p. 97-104 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • PPAR gamma
  • Mesenchymal Stem Cells
  • Genes
  • RNA Sequence Analysis
  • High-Throughput Nucleotide Sequencing
  4 Scopus citations

• Inverse relationship between serum hsCRP concentration and hand grip strength in older adults: A nationwide population-based study

  Kim, B. J., Lee, S. H., Kwak, M. K., Isales, C. M., Koh, J. M. & Hamrick, M. W., Aug 1 2018, In: Aging. 10, 8, p. 2051-2061 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hand Strength
  • C-Reactive Protein
  • Muscle Strength
  • Serum
  • Population
  3 Scopus citations

• Listeriolysin O causes ENaC dysfunction in human airway epithelial cells

  Yang, G., Pillich, H., White, R., Czikora, I., Pochic, I., Yue, Q., Hudel, M., Gorshkov, B. A., Verin, A. D., Sridhar, S., Isales, C. M., Eaton, D. C., Hamacher, J., Chakraborty, T. & Lucas, R., Feb 11 2018, In: Toxins. 10, 2, 79.

  Research output: Contribution to journal › Article › peer-review

  • Listeria monocytogenes hlyA protein
  • Epithelial Cells
  • AP301 peptide
  • Chemical activation
  • Pulmonary Edema
  1 Scopus citations

• Menopause and age-related bone loss

  Isales, C. M. & Seeman, E., Jan 1 2018, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. wiley, p. 155-161 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Menopause
  • Bone
  • Osteoporosis
  • Bone and Bones
  • Bone Remodeling
  2 Scopus citations

• Modulation of miRNAS by vitamin C in human bone marrow stromal cells

  Kolhe, R., Mondal, A. K., Pundkar, C., Periyasamy-Thandavan, S., Mendhe, B., Hunter, M., Isales, C. M., Hill, W. D., Hamrick, M. W. & Fulzele, S., Feb 8 2018, In: Nutrients. 10, 2, 186.

  Research output: Contribution to journal › Article › peer-review

  • mesenchymal stromal cells
  • microRNA
  • Ascorbic Acid
  • Mesenchymal Stem Cells
  • MicroRNAs
  9 Scopus citations

• Protein kinase D1 conditional null mice show minimal bone loss following ovariectomy

  Bollag, W. B., Ding, K. H., Choudhary, V., Xu, J., Zhong, Q., Elsayed, R., Bailey, L. J., Elsalanty, M., Yu, K., Johnson, M. H., McGee-Lawrence, M. E. & Isales, C. M., Oct 15 2018, In: Molecular and Cellular Endocrinology. 474, p. 176-183 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ovariectomy
  • Bone
  • Protein Kinases
  • Bone and Bones
  • Knockout Mice
  1 Scopus citations

• The positive association of total protein intake with femoral neck strength (KNHANES IV)

  Kim, B. J., Lee, S. H., Isales, C. M., Koh, J. M. & Hamrick, M. W., Jun 1 2018, In: Osteoporosis International. 29, 6, p. 1397-1405 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Femur Neck
  • Dietary Proteins
  • Bone and Bones
  • Proteins
  • Bone Density
  7 Scopus citations
• 2017

  Association of DPP-4 activity with BMD, body composition, and incident hip fracture: the Cardiovascular Health Study

  Carbone, L. D., Bůžková, P., Fink, H. A., Robbins, J. A., Bethel, M., Isales, C. M. & Hill, W. D., May 1 2017, In: Osteoporosis International. 28, 5, p. 1631-1640 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hip Fractures
  • Body Composition
  • Bone Density
  • Health
  • Independent Living
  9 Scopus citations

• Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

  Kolhe, R. B., Hunter, D. M., Liu, S., Jadeja, R. N., Pundkar, C., Mondal, A. K., Mendhe, B., Drewry, M., Rojiani, M. V., Liu, Y., Isales, C. M., Guldberg, R. E., Hamrick, M. W. & Fulzele, S. T., Dec 1 2017, In: Scientific reports. 7, 1, 2029.

  Research output: Contribution to journal › Article › peer-review

  • Synovial Fluid
  • Osteoarthritis
  • MicroRNAs
  • Exosomes
  • Genes
  78 Scopus citations

• Insulin Resistance and the IGF-I-Cortical Bone Relationship in Children Ages 9 to 13 Years

  Kindler, J. M., Pollock, N. K., Laing, E. M., Oshri, A., Jenkins, N. T., Isales, C. M., Hamrick, M. W., Ding, K. H., Hausman, D. B., McCabe, G. P., Martin, B. R., Hill Gallant, K. M., Warden, S. J., Weaver, C. M., Peacock, M. & Lewis, R. D., Jul 2017, In: Journal of Bone and Mineral Research. 32, 7, p. 1537-1545 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cortical Bone
  • Insulin-Like Growth Factor I
  • Insulin Resistance
  • Child
  • Homeostasis
  11 Scopus citations

• Intestinal incretins and the regulation of bone physiology

  Ramsey, W. & Isales, C. M., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 13-33 21 p. (Advances in Experimental Medicine and Biology; vol. 1033).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Incretins
  • Physiology
  • Bone
  • Gastric Inhibitory Polypeptide
  • Hormones
  12 Scopus citations

• Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

  Refaey, M. E., McGee-Lawrence, M. E., Fulzele, S., Kennedy, E. J., Bollag, W. B., Elsalanty, M., Zhong, Q., Ding, K. H., Bendzunas, N. G., Shi, X. M., Xu, J., Hill, W. D., Johnson, M. H., Hunter, M., Pierce, J. L., Yu, K., Hamrick, M. W. & Isales, C. M., Nov 2017, In: Journal of Bone and Mineral Research. 32, 11, p. 2182-2193 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Kynurenine
  • Tryptophan
  • Bone and Bones
  • Aromatic Amino Acids
  • N'-formylkynurenine
  49 Scopus citations