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• 2021

  First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child’s genetic risk

  The TEDDY study group, Mar 2021, In: Diabetologia. 64, 3, p. 591-602 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • Mothers
  • Pregnancy
  • Child

• Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: The TEDDY Study

  TEDDY study group, Jan 1 2021, In: Diabetes. 70, 1, p. 282-292 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolome
  • Vitamins
  • Age of Onset
  • Autoantibodies
  • Type 1 Diabetes Mellitus

• Retrospective Validation of a 168-Gene Expression Signature for Glioma Classification on a Single Molecule Counting Platform

  Tran, P. M. H., Tran, L. K. H., Satter, K. B., Purohit, S., Nechtman, J., Hopkins, D. I., Dos Santos, B., Bollag, R., Kolhe, R., Sharma, S. & She, J. X., Jan 2021, In: Cancers. 13, 3

  Research output: Contribution to journal › Article › peer-review

  • Transcriptome
  • Glioma
  • Survival
  • RNA
  • cdc Genes
• 2020

  A 73-gene proliferative transcriptomic signature predicts uterine serous carcinoma patient survival and response to primary therapy

  Tran, L. K. H., Tran, P. M. H., Mysona, D. P., Purohit, S. B., Myers, E., Lee, W. S., Dun, B., Xu, D., Liu, H., Hopkins, D., Nechtman, J., Scelsi, C. L., Mittal, P. K., Kleven, D., Wallbillich, J. J., Rungruang, B., Ghamande, S. & She, J. X., May 2020, In: Gynecologic Oncology. 157, 2, p. 340-347 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Carcinoma
  • Survival
  • Genes
  • Therapeutics
  • Primary Cell Culture
  1 Scopus citations

• A combined risk score enhances prediction of type 1 diabetes among susceptible children

  Committees, Aug 1 2020, In: Nature Medicine. 26, 8, p. 1247-1255 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Medical problems
  • Type 1 Diabetes Mellitus
  • Autoantibodies
  • Ketosis
  • Child
  4 Scopus citations

• Are There Survival Differences Between Women with Equivalent Residual Disease After Interval Cytoreductive Surgery Compared with Primary Cytoreductive Surgery for Advanced Ovarian and Peritoneal Cancer?

  Mysona, D. P., Ghamande, S., She, J. X., Tran, L., Tran, P., Rungruang, B. J., Chan, J. K., Bae-Jump, V. & Gehrig, P. A., 2020, (Accepted/In press) In: Annals of surgical oncology.

  Research output: Contribution to journal › Article › peer-review

  • Cytoreduction Surgical Procedures
  • Ovarian Neoplasms
  • Survival
  • Residual Neoplasm
  • Neoplasms

• Better survival is observed in cervical cancer patients positive for specific anti-glycan antibodies and receiving brachytherapy

  Purohit, S., Ferris, D. G., Alvarez, M., Tran, P. M. H., Tran, L. K. H., Mysona, D. P., Hopkins, D., Zhi, W., Dun, B., Wallbillich, J. J., Cummings, R. D., Wang, P. G. & She, J. X., Apr 2020, In: Gynecologic Oncology. 157, 1, p. 181-187 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Brachytherapy
  • Polysaccharides
  • Uterine Cervical Neoplasms
  • Anti-Idiotypic Antibodies
  • Survival
  2 Scopus citations

• Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers

  Mysona, D. P., Tran, L. K. H., Tran, P. M. H., Gehrig, P. A., Van Le, L., Ghamande, S., Rungruang, B. J., Java, J., Mann, A. K., Liao, J., Kapp, D. S., Santos, B. D., She, J. X. & Chan, J. K., Jan 2020, In: Gynecologic Oncology. 156, 1, p. 77-84 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Drug Therapy
  • Neoplasms
  • Machine Learning
  • Survival
  • Lymph Node Excision
  2 Scopus citations

• Comparative analysis of transcriptomic profile, histology, and IDH mutation for classification of gliomas

  Tran, P. M. H., Tran, L. K. H., Nechtman, J., dos Santos, B., Purohit, S., Satter, K. B., Dun, B., Kolhe, R., Sharma, S., Bollag, R. & She, J. X., Dec 2020, In: Scientific reports. 10, 1, 20651.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glioma
  • Histology
  • Mutation
  • splenotritin
  • Oligodendroglioma
  1 Scopus citations

• Distinct growth phases in early life associated with the risk of type 1 diabetes: The teddy study

  TEDDY study group, Mar 1 2020, In: Diabetes Care. 43, 3, p. 556-562 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Type 1 Diabetes Mellitus
  • Autoimmunity
  • Growth
  • Weight Gain
  • Child
  3 Scopus citations

• Hierarchical order of distinct autoantibody spreading and progression to type 1 diabetes in the Teddy study

  TEDDY study group, Sep 2020, In: Diabetes Care. 43, 9, p. 2066-2073 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • Insulin Antibodies
  • Zinc Transporter 8
  • Insulinoma
  1 Scopus citations

• Longitudinal metabolome-wide signals prior to the appearance of a first islet autoantibody in children participating in the TEDDY study

  Li, Q., Parikh, H., Butterworth, M. D., Lernmark, Å., Hagopian, W., Rewers, M., She, J. X., Toppari, J., Ziegler, A. G., Akolkar, B., Fiehn, O., Fan, S., Krischer, J. P., Rewers, M., Barbour, A., Bautista, K., Baxter, J., Felipe-Morales, D., Driscoll, K., Frohnert, B. I. & 236 others, Stahl, M., Gesualdo, P., Hoffman, M., Karban, R., Liu, E., Norris, J., Peacock, S., Shorrosh, H., Steck, A., Stern, M., Villegas, E., Waugh, K., Toppari, J., Simell, O. G., Adamsson, A., Ahonen, S., Åkerlund, M., Hakola, L., Hekkala, A., Holappa, H., Hyöty, H., Ikonen, A., Ilonen, J., Jäminki, S., Jokipuu, S., Karlsson, L., Kero, J., Kähönen, M., Knip, M., Koivikko, M. L., Koskinen, M., Koreasalo, M., Kurppa, K., Kytölä, J., Latva-Aho, T., Lindfors, K., Lönnrot, M., Mäntymäki, E., Mattila, M., Miettinen, M., Multasuo, K., Mykkänen, T., Niininen, T., Niinistö, S., Nyblom, M., Oikarinen, S., Ollikainen, P., Othmani, Z., Pohjola, S., Rajala, P., Rautanen, J., Riikonen, A., Riski, E., Pekkola, M., Romo, M., Ruohonen, S., Simell, S., Sjöberg, M., Stenius, A., Tossavainen, P., Vähä-Mäkilä, M., Vainionpää, S., Varjonen, E., Veijola, R., Viinikangas, I., Virtanen, S. M., She, J. X., Schatz, D., Hopkins, D., Steed, L., Bryant, J., Silvis, K., Haller, M., Gardiner, M., McIndoe, R., Sharma, A., Anderson, S. W., Jacobsen, L., Marks, J., Towe, P. D., Ziegler, A. G., Bonifacio, E., Gavrisan, A., Gezginci, C., Heublein, A., Hoffmann, V., Hummel, S., Keimer, A., Knopff, A., Koch, C., Koletzko, S., Ramminger, C., Roth, R., Scholz, M., Stock, J., Warncke, K., Wendel, L., Winkler, C., Lernmark, Å., Agardh, D., Aronsson, C. A., Ask, M., Bennet, R., Cilio, C., Engqvist, H., Ericson-Hallström, E., Fors, A., Fransson, L., Gard, T., Hansen, M., Jisser, H., Johansen, F., Jonsdottir, B., Jovic, S., Larsson, H. E., Lindström, M., Lundgren, M., Maziarz, M., Månsson-Martinez, M., Markan, M., Melin, J., Mestan, Z., Nilsson, C., Ottosson, K., Rahmati, K., Ramelius, A., Salami, F., Sjöberg, A., Sjöberg, B., Svensson, M., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Hagopian, W. A., Killian, M., Crouch, C. C., Skidmore, J., Chavoshi, M., Hervey, R., Lyons, R., Meyer, A., Mulenga, D., Radtke, J., Romancik, M., Schmitt, D., Zink, S., Becker, D., Franciscus, M., Smith, M. E. D. E., Daftary, A., Klein, M. B., Yates, C., Krischer, J. P., Austin-Gonzalez, S., Avendano, M., Baethke, S., Brown, R., Burkhardt, B., Butterworth, M., Clasen, J., Cuthbertson, D., Dankyi, S., Eberhard, C., Fiske, S., Garmeson, J., Gowda, V., Heyman, K., Hsiao, B., Karges, C., Laras, F. P., Lee, H. S., Li, Q., Liu, S., Liu, X., Lynch, K., Maguire, C., Malloy, J., McCarthy, C., Merrell, A., Parikh, H., Quigley, R., Remedios, C., Shaffer, C., Smith, L., Smith, S., Sulman, N., Tamura, R., Tewey, D., Toth, M., Uusitalo, U., Vehik, K., Vijayakandipan, P., Wood, K., Yang, J., Abbondondolo, M., Ballard, L., Hadley, D., McLeod, W., Meulemans, S., Akolkar, B., Bourcier, K., Briese, T., Johnson, S. B., Triplett, E., Yu, L., Miao, D., Bingley, P., Williams, A., Chandler, K., Ball, O., Kelland, I., Grace, S., Erlich, H., Mack, S. J., Fear, A. L., Fiehn, O., Wikoff, B., Defelice, B., Grapov, D., Kind, T., Palazoglu, M., Valdiviez, L., Wancewicz, B., Wohlgemuth, G., Wong, J., Rich, S. S., Chen, W. M., Onengut-Gumuscu, S., Farber, E., Pickin, R. R., Davis, J., Davis, J., Gallo, D., Bonnie, J. & Campolieto, P., Mar 1 2020, In: Diabetes. 69, 3, p. 465-476 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metabolome
  • Autoantibodies
  • Child
  • Dehydroascorbic Acid
  • Aminobutyrates
  2 Scopus citations

• Long term survival outcomes of stage I mucinous ovarian cancer - A clinical calculator predictive of chemotherapy benefit

  Richardson, M. T., Mysona, D. P., Klein, D. A., Mann, A., Liao, C. I., Diver, E. J., Darcy, K. M., Tian, C., She, J. X., Ghamande, S., Van Le, L., Kapp, D. S. & Chan, J. K., Oct 2020, In: Gynecologic Oncology. 159, 1, p. 118-128 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ovarian Neoplasms
  • Drug Therapy
  • Adjuvant Chemotherapy
  • Survival
  • Ascites

• Senescence-associated secretory phenotype determines survival and therapeutic response in cervical cancer

  Purohit, S., Zhi, W., Ferris, D. G., Alverez, M., Tran, L. K. H., Tran, P. M. H., Dun, B., Hopkins, D., Dos Santos, B., Ghamande, S. & She, J. X., Oct 2020, In: Cancers. 12, 10, p. 1-19 19 p., 2899.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cellular Senescence
  • Uterine Cervical Neoplasms
  • Survival
  • Phenotype
  • Machine Learning
  1 Scopus citations
• 2019

  A combined score of clinical factors and serum proteins can predict time to recurrence in high grade serous ovarian cancer

  Mysona, D., Pyrzak, A., Purohit, S., Zhi, W., Sharma, A., Tran, L., Tran, P., Bai, S., Rungruang, B., Ghamande, S. & She, J. X., Mar 2019, In: Gynecologic Oncology. 152, 3, p. 574-580 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ovarian Neoplasms
  • Blood Proteins
  • Recurrence
  • Progression-Free Survival
  • Proteins
  8 Scopus citations

• A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential

  Gobin, E., Bagwell, K., Wagner, J., Mysona, D., Sandirasegarane, S., Smith, N., Bai, S., Sharma, A., Schleifer, R. & She, J. X., Jun 14 2019, In: BMC Cancer. 19, 1, 581.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metalloproteases
  • Transcriptome
  • Matrix Metalloproteinases
  • Neoplasms
  • Genes
  29 Scopus citations

• Association of gluten intake during the first 5 years of life with incidence of celiac disease autoimmunity and celiac disease among children at increased risk

  Andrén Aronsson, C., Lee, H. S., Hård Af Segerstad, E. M., Uusitalo, U., Yang, J., Koletzko, S., Liu, E., Kurppa, K., Bingley, P. J., Toppari, J., Ziegler, A. G., She, J. X., Hagopian, W. A., Rewers, M., Akolkar, B., Krischer, J. P., Virtanen, S. M., Norris, J. M. & Agardh, D., Aug 13 2019, In: JAMA - Journal of the American Medical Association. 322, 6, p. 514-523 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Glutens
  • Celiac Disease
  • Autoimmunity
  • Incidence
  • Child
  27 Scopus citations

• Cell-based high throughput screening identified a novel compound that promotes regulatory T cells and prevents autoimmune colitis

  Mao, R., Liu, H., Yi, B., Purohit, S., Kuczma, M., Kraj, P. & She, J. X., Nov 2019, In: Biochemical Pharmacology. 169, 113618.

  Research output: Contribution to journal › Article › peer-review

  • T-cells
  • Colitis
  • Regulatory T-Lymphocytes
  • Screening
  • Lead compounds

• Early probiotic supplementation and the risk of celiac disease in children at genetic risk

  TEDDY study group, Aug 2019, In: Nutrients. 11, 8, 1790.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • celiac disease
  • Celiac Disease
  • Probiotics
  • probiotics
  • autoimmunity
  8 Scopus citations

• Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families

  The TEDDY study group, Apr 1 2019, In: Diabetes. 68, 4, p. 847-857 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Type 1 Diabetes Mellitus
  • Child
  • Population
  • Genetic Predisposition to Disease
  • Autoimmunity
  10 Scopus citations

• Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study

  The TEDDY study group, Feb 1 2019, In: Pediatric Diabetes. 20, 1, p. 86-92 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary Supplements
  • Autoimmunity
  • Mothers
  • Autoantibodies
  • Vitamin D
  9 Scopus citations

• Metabolite-related dietary patterns and the development of islet autoimmunity

  The TEDDY study group, Dec 1 2019, In: Scientific reports. 9, 1, 14819.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Autoimmunity
  • Phospholipid Ethers
  • Sphingomyelins
  • Metabolomics
  • Seroconversion
  8 Scopus citations

• Predicting islet cell autoimmunity and type 1 diabetes: An 8-year teddy study progress report

  TEDDY study group, Jun 1 2019, In: Diabetes Care. 42, 6, p. 1051-1060 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Islets of Langerhans
  • Autoimmunity
  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • ROC Curve
  20 Scopus citations

• Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

  The TEDDY study group, May 2019, In: Pediatric Diabetes. 20, 3, p. 263-270 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • Logistic Models
  • Child
  • Insulinoma
  7 Scopus citations

• Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study

  Beyerlein, A., Bonifacio, E., Vehik, K., Hippich, M., Winkler, C., Frohnert, B. I., Steck, A. K., Hagopian, W. A., Krischer, J. P., Lernmark, Å., Rewers, M. J., She, J. X., Toppari, J., Akolkar, B., Rich, S. S. & Ziegler, A. G., Sep 1 2019, In: Journal of medical genetics. 56, 9, p. 602-605 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoimmunity
  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • HLA Antigens
  • Genotype
  5 Scopus citations

• Prospective virome analyses in young children at increased genetic risk for type 1 diabetes

  The TEDDY study group, Dec 1 2019, In: Nature Medicine. 25, 12, p. 1865-1872 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Viruses
  • Medical problems
  • Autoimmunity
  • Type 1 Diabetes Mellitus
  • Enterovirus
  34 Scopus citations

• The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children

  TEDDY study group, Sep 18 2019, In: BMC pediatrics. 19, 1, 339.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Breast Feeding
  • Respiratory Tract Infections
  • Infection
  • Child
  • Otitis Media

• Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children

  for the TEDDY Study Group*, Jan 1 2019, In: Diabetes. 68, 1, p. 119-130 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • Child
  • Insulinoma
  • HLA-DR3 Antigen
  13 Scopus citations
• 2018

  Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study

  for the TEDDY Study Group, Mar 1 2018, In: Journal of Pediatric Gastroenterology and Nutrition. 66, 3, p. 417-424 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Celiac Disease
  • Cesarean Section
  • Autoimmunity
  • Confidence Intervals
  • Nonparametric Statistics
  18 Scopus citations

• Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study (Diabetologia, (2017), 10.1007/s00125-017-4365-5)

  On behalf of the TEDDY Study Group, Jan 1 2018, In: Diabetologia. 61, 1, p. 254 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Autoimmunity
  • Respiratory Tract Infections
  • Type 1 Diabetes Mellitus
  • Single Nucleotide Polymorphism
  • Emotions
  1 Scopus citations

• Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

  Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In: International journal of molecular sciences. 19, 2, 577.

  Research output: Contribution to journal › Article › peer-review

  • Keratin
  • keratins
  • Keratin-8
  • Anaplastic Thyroid Carcinoma
  • Cytoskeletal Proteins
  4 Scopus citations

• Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

  Tailor, P. D., Kodeboyina, S. K., Bai, S., Sharma, S., Ratnani, A., Copland, J. A., She, J-X., Sharma, A. K. & Patel, N., Apr 1 2018, In: Oncotarget. 9, 25, p. 17876-17888 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Kallikreins
  • Renal Cell Carcinoma
  • Biomarkers
  • Genes
  • Neoplasms
  17 Scopus citations

• Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children

  for the TEDDY Study Group, Apr 2018, In: PLoS Medicine. 15, 4, e1002548.

  Research output: Contribution to journal › Article › peer-review

  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • Prospective Studies
  • Child
  • Genotype
  39 Scopus citations

• Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - A preliminary report

  Shiao, S. P. K., Xiao, H., Dong, L., Wang, X., Liu, K., She, J. & Shi, H., May 22 2018, In: Oncotarget. 9, 39, p. 25557-25571 15 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Methylation
  • Methylation
  • Colorectal Neoplasms
  • Genome
  • Neoplasm Genes
  2 Scopus citations

• Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies

  on behalf of & TEDDY study group, Jan 2018, In: Journal of Autoimmunity. 86, p. 93-103 11 p.

  Research output: Contribution to journal › Article › peer-review

  • HLA Antigens
  • Respiratory Tract Infections
  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • Child
  11 Scopus citations

• Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort

  TEDDY study group, May 2018, In: Journal of Autoimmunity. 89, p. 90-100 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoimmunity
  • Type 1 Diabetes Mellitus
  • Single Nucleotide Polymorphism
  • Genes
  • Cohort Studies
  18 Scopus citations

• Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

  Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J. X., Belin de Chantemele, E. J. & Csányi, G., Sep 2018, In: British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Imipramine
  • United States Food and Drug Administration
  • Pharmaceutical Preparations
  • Endocytosis
  • Electron Scanning Microscopy
  20 Scopus citations

• KLHL5 knockdown increases cellular sensitivity to anticancer drugs

  Schleifer, R. J., Li, S., Nechtman, W., Miller, E., Bai, S., Sharma, A. & She, J. X., Dec 1 2018, In: Oncotarget. 9, 100, p. 37429-37438 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pharmaceutical Preparations
  • Neoplasms
  • Cell Cycle
  • Aurora Kinases
  • Cullin Proteins
  6 Scopus citations

• Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

  Purohit, S. B., Li, T., Guan, W., Song, X., Song, J., Tian, Y., Li, L., Sharma, A. K., Dun, B., Mysona, D., Ghamande, S. A., Rungruang, B. J., Cummings, R. D., Wang, P. G. & She, J-X., Dec 1 2018, In: Nature communications. 9, 1, 258.

  Research output: Contribution to journal › Article › peer-review

  • antibodies
  • beads
  • Polysaccharides
  • Carrier Proteins
  • proteins
  27 Scopus citations

• Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

  for the TEDDY Study Group, Jan 1 2018, In: Diabetologia. 61, 1, p. 193-202 10 p.

  Research output: Contribution to journal › Article › peer-review

  • pandemrix
  • Autoimmunity
  • Type 1 Diabetes Mellitus
  • Vaccination
  • Autoantibodies
  5 Scopus citations

• Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

  Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Lernmark, Å., Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J-X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., Jan 1 2018, In: Diabetes. 67, 1, p. 146-154 9 p.

  Research output: Contribution to journal › Article › peer-review

  • 25-hydroxyvitamin D
  • Autoimmunity
  • Vitamin D
  • Type 1 Diabetes Mellitus
  • 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
  36 Scopus citations

• Proteins of TNF-α and IL6 pathways are elevated in serum of type-1 diabetes patients with microalbuminuria

  Purohit, S. B., Sharma, A. K., Zhi, W., Bai, S., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D. & She, J-X., Jan 31 2018, In: Frontiers in immunology. 9, JAN, 154.

  Research output: Contribution to journal › Article › peer-review

  • Type 1 Diabetes Mellitus
  • Interleukin-6
  • Serum
  • Cytokine Receptor gp130
  • Proteins
  4 Scopus citations

• Proteomic approach to identify biomarkers for invasive cervix cancer - a prospective pilot study

  Mysona, D., Pyrzak, A., Allen, J., Powell, M., Kleven, D., Zhi, W., Sharma, A., Bai, S., She, J. X., Rungruang, B. & Ghamande, S., Jan 1 2018, In: European Journal of Gynaecological Oncology. 39, 5, p. 737-742 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Uterine Cervical Neoplasms
  • Biomarkers
  • Prospective Studies
  • Serum

• Temporal development of the gut microbiome in early childhood from the TEDDY study

  Stewart, C. J., Ajami, N. J., O’Brien, J. L., Hutchinson, D. S., Smith, D. P., Wong, M. C., Ross, M. C., Lloyd, R. E., Doddapaneni, H. V., Metcalf, G. A., Muzny, D., Gibbs, R. A., Vatanen, T., Huttenhower, C., Xavier, R. J., Rewers, M., Hagopian, W., Toppari, J., Ziegler, A. G., She, J-X. & 6 others, Akolkar, B., Lernmark, A., Hyoty, H., Vehik, K., Krischer, J. P. & Petrosino, J. F., Oct 25 2018, In: Nature. 562, 7728, p. 583-588 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Gastrointestinal Microbiome
  • Bacteroides
  • Human Milk
  • Autoimmunity
  305 Scopus citations

• The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

  The TEDDY study group, Dec 1 2018, In: Current diabetes reports. 18, 12, 136.

  Research output: Contribution to journal › Review article › peer-review

  • Type 1 Diabetes Mellitus
  • Autoimmunity
  • Gene-Environment Interaction
  • Micronutrients
  • Thyroid Diseases
  18 Scopus citations

• The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

  Vatanen, T., Franzosa, E. A., Schwager, R., Tripathi, S., Arthur, T. D., Vehik, K., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Stewart, C. J., Ajami, N. J., Petrosino, J. F., Gevers, D., Lähdesmäki, H., Vlamakis, H. & 2 others, Huttenhower, C. & Xavier, R. J., Oct 25 2018, In: Nature. 562, 7728, p. 589-594 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Gastrointestinal Microbiome
  • Type 1 Diabetes Mellitus
  • Autoimmunity
  • Metagenome
  184 Scopus citations
• 2017

  Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity

  for the TEDDY Study Group, May 16 2017, In: BMC pediatrics. 17, 1, 127.

  Research output: Contribution to journal › Article › peer-review

  • Antipyretics
  • Autoimmunity
  • Analgesics
  • Acetaminophen
  • Child
  8 Scopus citations

• Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity

  Kemppainen, K. M., Vehik, K., Lynch, K. F., Larsson, H. E., Canepa, R. J., Simell, V., Koletzko, S., Liu, E., Simell, O. G., Toppari, J., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W. A., She, J-X., Akolkar, B., Schatz, D. A., Atkinson, M. A., Blaser, M. J., Krischer, J. P. & 185 others, Hyöty, H., Agardh, D., Triplett, E. W., Bautista, K., Baxter, J., Bedoy, R., Felipe-Morales, D., Driscoll, K., Frohnert, B. I., Gesualdo, P., Hoffman, M., Karban, R., Norris, J., Samper-Imaz, A., Steck, A., Waugh, K., Wright, H., Adamsson, A., Ahonen, S., Ilonen, J., Jokipuu, S., Kallio, T., Karlsson, L., Kähönen, M., Knip, M., Kovanen, L., Koreasalo, M., Kurppa, K., Latva-Aho, T., Lönnrot, M., Mäntymäki, E., Multasuo, K., Mykkänen, J., Niininen, T., Niinistö, S., Nyblom, M., Rajala, P., Rautanen, J., Riikonen, A., Riikonen, M., Rouhiainen, J., Romo, M., Simell, T., Sjöberg, M., Stenius, A., Leppänen, M., Vainionpää, S., Varjonen, E., Veijola, R., Virtanen, S. M., Vähä-Mäkilä, M., Åkerlund, M., Lindfors, K., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Adams, J., Silvis, K., Haller, M., Gardiner, M., McIndoe, R. A., Sharma, A. K., William, J., Young, G., Anderson, S. W., Jacobsen, L., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Janz, N., Kersting, M., Knopff, A., Peplow, C., Roth, R., Scholz, M., Stock, J., Warncke, K., Wendel, L., Winkler, C., Aronsson, C. A., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallström, E., Fransson, L., Gard, T., Gerardsson, J., Bennet, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonsdottir, B., Lindström, M., Lundgren, M., Månsson-Martinez, M., Markan, M., Melin, J., Mestan, Z., Ottosson, K., Rahmati, K., Ramelius, A., Salami, F., Sibthorpe, S., Sjöberg, B., Swartling, U., Amboh, E. T., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Killian, M., Crouch, C. C., Skidmore, J., Carson, J., Dalzell, M., Dunson, K., Hervey, R., Johnson, C., Lyons, R., Meyer, A., Mulenga, D., Tarr, A., Uland, M., Willis, J., Becker, D., Franciscus, M., Smith, M. E. D. E., Daftary, A., Klein, M. B., Yates, C., Abbondondolo, M., Austin-Gonzalez, S., Avendano, M., Baethke, S., Brown, R., Burkhardt, B., Butterworth, M., Clasen, J., Cuthbertson, D., Eberhard, C., Fiske, S., Garcia, D., Garmeson, J., Gowda, V., Heyman, K., Laras, F. P., Lee, H. S., Liu, S., Liu, X., Lynch, K., Malloy, J., McCarthy, C., Meulemans, S., Parikh, H., Shaffer, C., Smith, L., Smith, S., Sulman, N., Tamura, R., Uusitalo, U., Vijayakandipan, P., Wood, K., Yang, J., Ballard, L., Hadley, D., McLeod, W., Bourcier, K., Briese, T., Johnson, S. B., Yu, L., Miao, D., Bingley, P., William's, A., Chandler, K., Rokni, S., Willia, C., Wyatt, R., George, G., Grace, S. & Mulholland, N., Dec 2017, In: JAMA Pediatrics. 171, 12, p. 1217-1225 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Celiac Disease
  • Autoimmunity
  • Anti-Bacterial Agents
  • Autoantibodies
  • Type 1 Diabetes Mellitus
  43 Scopus citations

• Blood-based biomarkers for precision medicine in lung cancer: Precision radiation therapy

  De Ruysscher, D., Jin, J., Lautenschlaeger, T., She, J. X., Liao, Z. & Kong, F. M. S., Dec 1 2017, In: Translational Lung Cancer Research. 6, 6, p. 661-669 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Precision Medicine
  • Lung Neoplasms
  • Radiotherapy
  • Biomarkers
  • Organs at Risk
  7 Scopus citations

• Co-occurrence of type 1 diabetes and celiac disease autoimmunity

  Hagopian, W., Lee, H. S., Liu, E., Rewers, M., She, J. X., Ziegler, A. G., Lernmark, A., Toppari, J., Rich, S. S., Krischer, J. P., Erlich, H., Akolkar, B. & Agardh, D., Nov 2017, In: Pediatrics. 140, 5, e20171305.

  Research output: Contribution to journal › Article › peer-review

  • Celiac Disease
  • Autoimmunity
  • Autoantibodies
  • Type 1 Diabetes Mellitus
  • transglutaminase 2
  33 Scopus citations