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• Targeted delivery of small noncoding RNA for glioblastoma

  Yoo, J. Y., Yeh, M., Kaur, B. & Lee, T. J., Mar 1 2021, In: Cancer Letters. 500, p. 274-280 7 p.

  Research output: Contribution to journal › Short survey › peer-review
  6 Scopus citations

• Targeted disruption of cd73/ecto-5′-nucleotidase alters thromboregulation and augments vascular inflammatory response

  Koszalka, P., Özüyaman, B., Huo, Y., Zernecke, A., Flögel, U., Braun, N., Buchheiser, A., Decking, U. K. M., Smith, M. L., Sévigny, J., Gear, A., Weber, A. A., Molojavyi, A., Ding, Z., Weber, C., Ley, K., Zimmermann, H., Gödecke, A. & Schrader, J., Oct 15 2004, In: Circulation research. 95, 8, p. 814-821 8 p.

  Research output: Contribution to journal › Article › peer-review
  215 Scopus citations

• Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation

  Smith, B. T., Mussell, J. C., Fleming, P. A., Barth, J. L., Spyropoulos, D. D., Cooley, M. A., Drake, C. J. & Argraves, W. S., Jun 20 2006, In: BMC Developmental Biology. 6, 30.

  Research output: Contribution to journal › Article › peer-review
  56 Scopus citations

• Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation for stress-inducible hsp molecular chaperones

  Zhang, Y., Huang, L., Zhang, J., Moskophidis, D. & Mivechi, N. F., 2002, In: Journal of cellular biochemistry. 86, 2, p. 376-393 18 p.

  Research output: Contribution to journal › Article › peer-review
  122 Scopus citations

• Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis

  Wang, G., Zhang, J., Moskophidis, D. & Mivechi, N. F., May 1 2003, In: Genesis. 36, 1, p. 48-61 14 p.

  Research output: Contribution to journal › Article › peer-review
  119 Scopus citations

• Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion

  Chew, C. S., Chen, X., Bollag, R. J., Isales, C., Ding, K. H. & Zhang, H., Jul 2008, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 295, 1, p. G37-G44

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Targeted disruption of the meprin metalloproteinase β gene protects against renal ischemia-reperfusion injury in mice

  Bylander, J., Li, Q., Ramesh, G., Zhang, B., Reeves, W. B. & Bond, J. S., Mar 2008, In: American Journal of Physiology - Renal Physiology. 294, 3, p. F480-F490

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Targeted disruption of the myocilin gene (Myoc) suggests that human glaucoma-causing mutations are gain of function

  Byong Su Kim, S. K., Savinova, O. V., Reedy, M. V., Martin, J., Lun, Y., Gan, L., Smith, R. S., Tomarev, S. I., John, S. W. M. & Johnson, R. L., 2001, In: Molecular and Cellular Biology. 21, 22, p. 7707-7713 7 p.

  Research output: Contribution to journal › Article › peer-review
  217 Scopus citations

• Targeted expression of activated erbB-2 to the epidermis of transgenic mice elicits striking developmental abnormalities in the epidermis and hair follicles

  Xie, W., Wu, X., Chow, L. T., Chin, E., Paterson, A. J. & Kudlow, J. E., 1998, In: Cell Growth and Differentiation. 9, 4, p. 313-325 13 p.

  Research output: Contribution to journal › Article › peer-review
  39 Scopus citations

• Targeted expression of a dominant negative epidermal growth factor receptor in the mammary gland of transgenic mice inhibits pubertal mammary duct development

  Xie, W., Paterson, A. J., Chin, E., Nabell, L. M. & Kudlow, J. E., 1997, In: Molecular Endocrinology. 11, 12, p. 1765-1781 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  104 Scopus citations

• Targeted fetal hemoglobin induction for treatment of beta hemoglobinopathies

  Perrine, S. P., Pace, B. S. & Faller, D. V., Apr 2014, In: Hematology/Oncology Clinics of North America. 28, 2, p. 233-248 16 p.

  Research output: Contribution to journal › Review article › peer-review
  35 Scopus citations

• Targeted gene therapy to antigen-presenting cells in the central nervous system using hematopoietic stem cells

  Lesniak, M. S., Kelleher, E., Pardoll, D. & Cui, Y., Dec 1 2005, In: Neurological Research. 27, 8, p. 820-826 7 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Targeted inactivation of EPS8 using dendrimer-mediated delivery of RNA interference

  Yuan, Q., Yeudall, W. A., Lee, E. & Yang, H., Feb 25 2019, In: International Journal of Pharmaceutics. 557, p. 178-181 4 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization.

  Koushik, S. V., Wang, J., Rogers, R., Moskofidis, D., Lambert, N. A., Creazzo, T. L. & Conway, S. J., May 2001, In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15, 7, p. 1209-1211 3 p.

  Research output: Contribution to journal › Article › peer-review
  218 Scopus citations

• Targeted knockout of a chemokine-like gene increases anxiety and fear responses

  Choi, J. H., Jeong, Y. M., Kim, S., Lee, B., Ariyasiri, K., Kim, H. T., Jung, S. H., Hwang, K. S., Choi, T. I., Park, C. O., Huh, W. K., Carl, M., Rosenfeld, J. A., Raskin, S., Ma, A., Gecz, J., Kim, H. G., Kim, J. S., Shin, H. C., Park, D. S., & 7 othersGerlai, R., Jamieson, B. B., Kim, J. S., Iremonger, K. J., Lee, S. H., Shin, H. S. & Kim, C. H., Jan 30 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 5, p. E1041-E1050

  Research output: Contribution to journal › Article › peer-review

  Open Access
  29 Scopus citations

• Targeted labeling of neurons in a specific functional micro-domain of the neocortex by combining intrinsic signal and two-photon imaging.

  O'Herron, P., Shen, Z., Lu, Z., Schramm, A. E., Levy, M. & Kara, P., 2012, In: Journal of visualized experiments : JoVE. 70, p. e50025

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome

  Quaynor, S. D., Bosley, M. E., Duckworth, C. G., Porter, K. R., Kim, S. H., Kim, H. G., Chorich, L. P., Sullivan, M. E., Choi, J. H., Cameron, R. S. & Layman, L. C., Dec 5 2016, In: Molecular and Cellular Endocrinology. 437, p. 86-96 11 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations

• Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses

  Huo, Y., Guo, X., Li, H., Xu, H., Halim, V., Zhang, W., Wang, H., Fan, Y. Y., Ong, K. T., Woo, S. L., Chapkin, R. S., Mashek, D. G., Chen, Y., Dong, H., Lu, F., Wei, L. & Wu, C., Jun 15 2012, In: Journal of Biological Chemistry. 287, 25, p. 21492-21500 9 p.

  Research output: Contribution to journal › Article › peer-review
  46 Scopus citations

• Targeted pretransplant host lymphocyte depletion prior to T-cell depleted reduced-intensity allogeneic stem cell transplantation

  Bishop, M. R., Steinberg, S. M., Gress, R. E., Hardy, N. M., Marchigiani, D., Kasten-Sportes, C., Dean, R., Pavletic, S. Z., Gea-Banacloche, J., Castro, K., Hakim, F., Krumlauf, M., Read, E. J., Carter, C., Leitman, S. F. & Fowler, D. H., Sep 2004, In: British Journal of Haematology. 126, 6, p. 837-843 7 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Targeted radiotherapy and immunotherapy of human neuroblastoma with G_d2 specific monoclonal antibodies

  Cheung, N. K. V., Munn, D., Kushner, B. H., Usmani, N. & Yeh, S. D. J., 1989, In: International Journal of Radiation Applications and Instrumentation.. 16, 2, p. 111-117,119-120

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

  Flynn, R., Paz, K., Du, J., Reichenbach, D. K., Taylor, P. A., Panoskaltsis-Mortari, A., Vulic, A., Luznik, L., MacDonald, K. K. P., Hill, G. R., Nyuydzefe, M. S., Weiss, J. M., Chen, W., Trzeciak, A., Serody, J. S., Aguilar, E. G., Murphy, W. J., Maillard, I., Munn, D. H., Koreth, J., & 6 othersCutler, C. S., Antin, J. H., Ritz, J., Waksal, S. D., Zanin-Zhorov, A. & Blazar, B. R., Apr 28 2016, In: Blood. 127, 17, p. 2144-2154 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  108 Scopus citations

• Targeted therapies for non-HPV-related head and neck cancer: challenges and opportunities in the context of predictive, preventive, and personalized medicine

  Shahoumi, L. A. & Yeudall, W. A., Sep 15 2019, In: EPMA Journal. 10, 3, p. 291-305 15 p.

  Research output: Contribution to journal › Review article › peer-review
  9 Scopus citations

• Targeted Therapies in Chronic Myeloid Leukemia

  Jabbour, E. & Cortes, J., Oct 30 2015, Targeted Therapy in Translational Cancer Research. Wiley-Blackwell, p. 111-120 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Targeted therapies in hematology and their impact on patient care: Chronic and acute myeloid leukemia

  Jabbour, E., Cortes, J., Ravandi, F., O'Brien, S. & Kantarjian, H., Oct 2013, In: Seminars in Hematology. 50, 4, p. 271-283 13 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Targeted therapy for chronic myeloid leukemia

  Cardama, A. Q. & Cortes, J., Jan 1 2011, Targeted Therapy for Solid Tumors and Hematologic Malignancies. Nova Science Publishers, Inc., p. 41-56 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Targeted therapy in chronic myeloid leukemia

  Jabbour, E., Cortes, J. E., Ghanem, H., O'Brien, S. & Kantarjian, H. M., Jan 2008, In: Expert Review of Anticancer Therapy. 8, 1, p. 99-110 12 p.

  Research output: Contribution to journal › Review article › peer-review
  39 Scopus citations

• Targeted therapy in non-small cell lung cancer

  Shou-Ching, T., Aug 2004, In: Chinese Journal of Lung Cancer. 7, 4, p. 284-289 6 p.

  Research output: Contribution to journal › Review article › peer-review
  2 Scopus citations

• Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA

  Kondo, S., Kondo, Y., Li, G., Silverman, R. H. & Cowell, J. K., Jun 25 1998, In: Oncogene. 16, 25, p. 3323-3330 8 p.

  Research output: Contribution to journal › Article › peer-review
  195 Scopus citations

• Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow.

  Klibanov, A. L., Rychak, J. J., Yang, W. C., Alikhani, S., Li, B., Acton, S., Lindner, J. R., Ley, K. & Kaul, S., Nov 2006, In: Contrast Media and Molecular Imaging. 1, 6, p. 259-266 8 p.

  Research output: Contribution to journal › Article › peer-review
  146 Scopus citations

• targetHub: A programmable interface for miRNA-gene interactions

  Manyam, G., Ivan, C., Calin, G. A. & Coombes, K. R., Oct 15 2013, In: Bioinformatics. 29, 20, p. 2657-2658 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• Targeting ABL and SRC kinases in chronic myeloid leukemia: Experience with dasatinib

  Quintás-Cardama, A., Kantarjian, H. & Cortes, J., Dec 2006, In: Future Oncology. 2, 6, p. 655-665 11 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Targeting adenoviral vectors for enhanced gene therapy of uterine leiomyomas

  Nair, S., Curiel, D. T., Rajaratnam, V., Thota, C. & Al-Hendy, A., Sep 2013, In: Human Reproduction. 28, 9, p. 2398-2406 9 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Targeting Anti-Angiogenic VEGF₁₆₅b–VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models

  Kuppuswamy, S., Annex, B. H. & Ganta, V. C., Sep 2022, In: Cells. 11, 17, 2676.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting a Single Codon to Rescue Septic Acute Kidney Injury

  Chen, G. & Dong, Z., Feb 1 2023, In: Journal of the American Society of Nephrology : JASN. 34, 2, p. 179-181 3 p.

  Research output: Contribution to journal › Article › peer-review

• Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy

  Zhou, H., Lei, X., Yan, Y., Lydic, T., Li, J., Weintraub, N. L., Su, H. & Chen, W., Jul 25 2019, In: JCI Insight. 4, 14, e129781.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Scopus citations

• Targeting autophagy as a strategy for drug discovery and therapeutic modulation

  Gao, L., Jauregui, C. E. & Teng, Y., Mar 2017, In: Future Medicinal Chemistry. 9, 3, p. 335-345 11 p.

  Research output: Contribution to journal › Review article › peer-review
  27 Scopus citations

• Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics

  Ajoolabady, A., Wang, S., Kroemer, G., Penninger, J. M., Uversky, V. N., Pratico, D., Henninger, N., Reiter, R. J., Bruno, A., Joshipura, K., Aslkhodapasandhokmabad, H., Klionsky, D. J. & Ren, J., Sep 2021, In: Pharmacology and Therapeutics. 225, 107848.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  52 Scopus citations

• Targeting Bone Marrow to Potentiate the Anti-Tumor Effect of Tyrosine Kinase Inhibitor in Preclinical Rat Model of Human Glioblastoma

  Shaaban, S., Alsulami, M., Arbab, S. A., Ara, R., Shankar, A., Iskander, A., Angara, K., Jain, M., Bagher-Ebadian, H., Achyut, B. R. & Arbab, A. S., Jul 19 2016, In: International Journal of Cancer Research. 12, 2, p. 69-81 13 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

  Kakarala, M., Brenner, D. E., Korkaya, H., Cheng, C., Tazi, K., Ginestier, C., Liu, S., Dontu, G. & Wicha, M. S., Aug 2010, In: Breast Cancer Research and Treatment. 122, 3, p. 777-785 9 p.

  Research output: Contribution to journal › Article › peer-review
  386 Scopus citations

• Targeting Cardiovascular Adverse Events of Metastatic Renal Cell Carcinoma Therapies

  Guha, A., Sayegh, N. & Agarwal, N., Jun 2022, In: JACC: CardioOncology. 4, 2, p. 235-237 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
  1 Scopus citations

• Targeting cholinergic system to modulate liver injury

  Jadeja, R. N., Rachakonda, V. P. & Khurana, S., Jan 1 2018, In: Current drug targets. 19, 8, p. 938-944 7 p.

  Research output: Contribution to journal › Review article › peer-review
  4 Scopus citations

• Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2⁺ Breast Cancer

  Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In: Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  53 Scopus citations

• Targeting endothelial barrier dysfunction caused by circulating bacterial and mitochondrial n-formyl peptides with deformylase

  Martinez-Quinones, P., Komic, A., McCarthy, C. G., Webb, R. C. & Wenceslau, C. F., 2019, In: Frontiers in immunology. 10, JUN, 1270.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Scopus citations

• Targeting Fc Receptor-Mediated Effects and the “Don’t Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer

  Tian, L., Xu, B., Teng, K. Y., Song, M., Zhu, Z., Chen, Y., Wang, J., Zhang, J., Feng, M., Kaur, B., Rodriguez, L., Caligiuri, M. A. & Yu, J., Jan 1 2022, In: Clinical Cancer Research. 28, 1, p. 201-214 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models

  Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In: Oncotarget. 7, 31, p. 49733-49742 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option

  Starlard-Davenport, A., Gu, Q. & Pace, B. S., Sep 2022, In: Molecular Diagnosis and Therapy. 26, 5, p. 497-509 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  3 Scopus citations

• Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma

  Kumai, T., Ohkuri, T., Nagato, T., Matsuda, Y., Oikawa, K., Aoki, N., Kimura, S., Celis, E., Harabuchi, Y. & Kobayashi, H., Nov 5 2015, In: Scientific reports. 5, 16280.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation

  Woan, K. V., Lienlaf, M., Perez-Villaroel, P., Lee, C., Cheng, F., Knox, T., Woods, D. M., Barrios, K., Powers, J., Sahakian, E., Wang, H. W., Canales, J., Marante, D., Smalley, K. S. M., Bergman, J., Seto, E., Kozikowski, A., Pinilla-Ibarz, J., Sarnaik, A., Celis, E., & 3 othersWeber, J., Sotomayor, E. M. & Villagra, A., Aug 1 2015, In: Molecular Oncology. 9, 7, p. 1447-1457 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  89 Scopus citations

• Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia

  Ganguly, S., Home, T., Yacoub, A., Kambhampati, S., Shi, H., Dandawate, P., Padhye, S., Saluja, A. K., McGuirk, J. & Rao, R., 2015, In: Oncotarget. 6, 31, p. 31767-31779 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations

• Targeting hyaluronic acid family for cancer chemoprevention and therapy

  Lokeshwar, V. B., Mirza, S. & Jordan, A., 2014, Advances in Cancer Research. Academic Press Inc., p. 35-65 31 p. (Advances in Cancer Research; vol. 123).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  110 Scopus citations