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  Activation of BNIP3-mediated mitophagy protects against renal ischemia–reperfusion injury

  Tang, C., Han, H., Liu, Z., Liu, Y., Yin, L., Cai, J., He, L., Liu, Y., Chen, G., Zhang, Z., Yin, X. M. & Dong, Z., Sep 1 2019, In: Cell Death and Disease. 10, 9, 677.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  83 Scopus citations

• Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells

  Cavanagh, L. L., Bonasio, R., Mazo, I. B., Halin, C., Cheng, G., van der Velden, A. W. M., Cariappa, A., Chase, C., Russell, P., Starnbach, M. N., Koni, P. A., Pillai, S., Weninger, W. & von Andrian, U. H., Oct 2005, In: Nature Immunology. 6, 10, p. 1029-1037 9 p.

  Research output: Contribution to journal › Article › peer-review
  178 Scopus citations

• Activation of calpain, cathepsin-b and caspase-3 during transient focal cerebral ischemia in rat model

  Chaitanya, G. V. & Babu, P. P., Nov 2008, In: Neurochemical Research. 33, 11, p. 2178-2186 9 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations

• Activation of calpain-2 by mediators in pulmonary vascular remodeling of pulmonary arterial hypertension

  Kovacs, L., Han, W., Rafikov, R., Bagi, Z., Offermanns, S., Saido, T. C., Black, S. M. & Su, Y., Mar 2016, In: American journal of respiratory cell and molecular biology. 54, 3, p. 384-393 10 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Activation of calpain by renin-angiotensin system in pleural mesothelial cells mediates tuberculous pleural fibrosis

  Yang, J., Xiang, F., Cai, P. C., Lu, Y. Z., Xu, X. X., Yu, F., Li, F. Z., Greer, P. A., Shi, H. Z., Zhou, Q., Xin, J. B., Ye, H., Su, Y. & Ma, W. L., Jul 1 2016, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 311, 1, p. L145-L153

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Scopus citations

• Activation of cAMP-dependent protein kinase is required for heterologous desensitization of adenylyl cyclase in S49 wild-type lymphoma cells.

  Clark, R. B., Kunkel, M. W., Friedman, J., Goka, T. J. & Johnson, J. A., Mar 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 5, p. 1442-1446 5 p.

  Research output: Contribution to journal › Article › peer-review
  106 Scopus citations

• Activation of caspase-2 in apoptosis

  Li, H., Bergeron, L., Cryns, V., Pasternack, M. S., Zhu, H., Shi, L., Greenberg, A. & Yuan, J., Aug 22 1997, In: Journal of Biological Chemistry. 272, 34, p. 21010-21017 8 p.

  Research output: Contribution to journal › Article › peer-review
  168 Scopus citations

• Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor

  Eldredge, E. R., Korf, G. M., Christensen, T. A., Connolly, D. C., Getz, M. J. & Maihle, N. J., Nov 1994, In: Molecular and Cellular Biology. 14, 11, p. 7527-7534 8 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Activation of cGMP-dependent protein kinase by protein kinase C

  Hou, Y., Lascola, J., Dulin, N. O., Ye, R. D. & Browning, D. D., May 9 2003, In: Journal of Biological Chemistry. 278, 19, p. 16706-16712 7 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Activation of c-Jun NH₂-terminal kinase 3 is mediated by the GluR6·PSD-95·MLK3 signaling module following cerebral ischemia in rat hippocampus

  Tian, H., Zhang, Q. G., Zhu, G. X., Pei, D. S., Guan, Q. H. & Zhang, G. Y., Nov 2 2005, In: Brain Research. 1061, 1, p. 57-66 10 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation

  Kevin Leach, J., Black, S. M., Schmidt-Ullrich, R. K. & Mikkelsen, R. B., May 3 2002, In: Journal of Biological Chemistry. 277, 18, p. 15400-15406 7 p.

  Research output: Contribution to journal › Article › peer-review
  116 Scopus citations

• Activation of cryptic metabolite production through gene disruption: Dimethyl furan-2,4-dicarboxylate produced by Streptomyces sahachiroi

  Simkhada, D., Zhang, H., Mori, S., Williams, H. & Watanabe, C. M. H., Aug 29 2013, In: Beilstein Journal of Organic Chemistry. 9, p. 1768-1773 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Scopus citations

• Activation of diverse signaling pathways by Ex-vivo delivery of multiple cytokines for myocardial repair

  Konoplyannikov, M., Haider, K. H., Lai, V. K., Ahmed, R. P. H., Jiang, S. & Ashraf, M., Jan 15 2013, In: Stem Cells and Development. 22, 2, p. 204-215 12 p.

  Research output: Contribution to journal › Article › peer-review
  23 Scopus citations

• Activation of endoplasmic reticulum stress response following trauma-hemorrhage

  Jian, B., Hsieh, C. H., Chen, J., Choudhry, M., Bland, K., Chaudry, I. & Raju, R., Nov 2008, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1782, 11, p. 621-626 6 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations

• Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and l-citrulline formation

  Schmidt, K., Martens-Lobenhoffer, J., Meinitzer, A., Graier, W. F., Torres, C. M., Venema, R. C. & Mayer, B., May 15 2010, In: Nitric Oxide - Biology and Chemistry. 22, 4, p. 281-289 9 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Activation of ERK5 is mediated by N-methyl-D-aspartate receptor and L-type voltage-gated calcium channel via Src involving oxidative stress after cerebral ischemia in rat hippocampus

  Wang, R. M., Zhang, Q. G. & Zhang, G. Y., Feb 26 2004, In: Neuroscience Letters. 357, 1, p. 13-16 4 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• Activation of extracellular signal-regulated kinase 5 may play a neuroprotective role in hippocampal CA3/DG region after cerebral ischemia

  Wang, R. M., Zhang, Q., Li, C. H. & Zhang, G. Y., May 1 2005, In: Journal of Neuroscience Research. 80, 3, p. 391-399 9 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains

  Hossain, M. A., Shen, Y., Knudson, I., Thakur, S., Stees, J. R., Qiu, Y., Pace, B. S., Peterson, K. R. & Bungert, J., 2016, In: Molecular Therapy - Nucleic Acids. 5, p. e378

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion

  Zhang, F., Li, C., Wang, R., Han, D., Zhang, Q. G., Zhou, C., Yu, H. M. & Zhang, G. Y., Dec 19 2007, In: Neuroscience. 150, 4, p. 938-949 12 p.

  Research output: Contribution to journal › Article › peer-review
  75 Scopus citations

• Activation of gelatinolytic/collagenolytic activity in dentin by self-etching adhesives

  Nishitani, Y., Yoshiyama, M., Wadgaonkar, B., Breschi, L., Mannello, F., Mazzoni, A., Carvalho, R. M., Tjäderhane, L., Tay, F. R. & Pashley, D. H., Apr 2006, In: European Journal of Oral Sciences. 114, 2, p. 160-166 7 p.

  Research output: Contribution to journal › Article › peer-review
  299 Scopus citations

• Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

  Singh, N., Gurav, A., Sivaprakasam, S., Brady, E., Padia, R., Shi, H., Thangaraju, M., Prasad, P. D., Manicassamy, S., Munn, D. H., Lee, J. R., Offermanns, S. & Ganapathy, V., Jan 16 2014, In: Immunity. 40, 1, p. 128-139 12 p.

  Research output: Contribution to journal › Article › peer-review
  1282 Scopus citations

• Activation of G protein-coupled estrogen receptor induces endotheliumindependent relaxation of coronary artery smooth muscle

  Yu, X., Ma, H., Barman, S. A., Liu, A. T., Sellers, M., Stallone, J. N., Prossnitz, E. R., White, R. E. & Han, G., Nov 2011, In: American Journal of Physiology - Endocrinology and Metabolism. 301, 5, p. E882-E888

  Research output: Contribution to journal › Article › peer-review
  75 Scopus citations

• Activation of hexosamine pathway impairs nitric oxide (NO)-dependent arteriolar dilations by increased protein O-GlcNAcylation

  Beleznai, T. & Bagi, Z., Mar 2012, In: Vascular Pharmacology. 56, 3-4, p. 115-121 7 p.

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• Activation of IL-11/STAT3 pathway in preconditioned human skeletal myoblasts blocks apoptotic cascade under oxidant stress

  Idris, N. M., Ashraf, M., Ahmed, R. P. H., Shujia, J. & Haider, K. H., Jan 2012, In: Regenerative Medicine. 7, 1, p. 47-57 11 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing

  Boini, K. M., Xia, M., Abais, J. M., Li, G., Pitzer, A. L., Gehr, T. W. B., Zhang, Y. & Li, P. L., May 2014, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 5, p. 836-845 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  66 Scopus citations

• Activation of mesangial cell MAPK in response to homocysteine

  Ingram, A. J., Krepinsky, J. C., James, L., Austin, R. C., Tang, D., Salapatek, A. M., Thai, K. & Scholey, J. W., Aug 2004, In: Kidney International. 66, 2, p. 733-745 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  42 Scopus citations

• Activation of midbrain structures by associative novelty and the formation of explicit memory in humans

  Schott, B. H., Sellner, D. B., Lauer, C. J., Habib, R., Frey, J. U., Guderian, S., Heinze, H. J. & Düzel, E., Jul 2004, In: Learning and Memory. 11, 4, p. 383-387 5 p.

  Research output: Contribution to journal › Article › peer-review
  103 Scopus citations

• Activation of mitochondrial ATP-sensitive K⁺ channel for cardiac protection against ischemic injury is dependent on protein kinase C activity

  Wang, Y., Hirai, K. & Ashraf, M., Oct 15 1999, In: Circulation research. 85, 8, p. 731-741 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  181 Scopus citations

• Activation of mitochondrial K(ATP) channel elicits late preconditioning against myocardial infarction via protein kinase C signaling pathway

  Takashi, E., Wang, Y. & Ashraf, M., Dec 3 1999, In: Circulation research. 85, 12, p. 1146-1153 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  152 Scopus citations

• Activation of muscarinic acetylcholine receptors enhances the release of endogenous cannabinoids in the hippocampus

  Kim, J., Isokawa, M., Ledent, C. & Alger, B. E., Dec 1 2002, In: Journal of Neuroscience. 22, 23, p. 10182-10191 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  259 Scopus citations

• Activation of myeloid TLR4 Mediates T lymphocyte polarization after traumatic brain injury

  Braun, M., Vaibhav, K., Saad, N., Fatima, S., Brann, D. W., Vender, J. R., Wang, L., Hoda, MD. N., Baban, B. & Dhandapani, K. M., May 1 2017, In: Journal of Immunology. 198, 9, p. 3615-3626 12 p.

  Research output: Contribution to journal › Article › peer-review
  39 Scopus citations

• Activation of NAD(P)H oxidase by lipid hydroperoxides: Mechanism of oxidant-mediated smooth muscle cytotoxicity

  Li, W. G., Stoll, L. L., Rice, J. B., Xu, S. P., Miller, F. J., Chatterjee, P., Hu, L., Oberley, L. W., Spector, A. A. & Weintraub, N. L., Apr 1 2003, In: Free Radical Biology and Medicine. 34, 7, p. 937-946 10 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations

• Activation of NF-κB by bradykinin through a Gα(q)- and Gβγ-dependent pathway that involves phosphoinositide 3-kinase and Akt

  Xie, P., Browning, D. D., Hay, N., Mackman, N. & Ye, R. D., Aug 11 2000, In: Journal of Biological Chemistry. 275, 32, p. 24907-24914 8 p.

  Research output: Contribution to journal › Article › peer-review
  124 Scopus citations

• Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia

  Zhang, C., Boini, K. M., Xia, M., Abais, J. M., Li, X., Liu, Q. & Li, P. L., Jul 2012, In: Hypertension. 60, 1, p. 154-162 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  148 Scopus citations

• Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors

  Gaisina, I. N., Lee, S. H., Kaidery, N. A., Ben Aissa, M., Ahuja, M., Smirnova, N. N., Wakade, S., Gaisin, A., Bourassa, M. W., Ratan, R. R., Nikulin, S. V., Poloznikov, A. A., Thomas, B., Thatcher, G. R. J. & Gazaryan, I. G., May 16 2018, In: ACS Chemical Neuroscience. 9, 5, p. 894-900 7 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice

  Kimbler, D. E., Shields, J., Yanasak, N., Vender, J. R. & Dhandapani, K. M., Jul 17 2012, In: PloS one. 7, 7, e41229.

  Research output: Contribution to journal › Article › peer-review
  115 Scopus citations

• Activation of p38 mitogen-activated protein kinase by lipopolysaccharide in human neutrophils requires nitric oxide-dependent cGMP accumulation

  Browning, D. D., Windes, N. D. & Ye, R. D., Jan 1 1999, In: Journal of Biological Chemistry. 274, 1, p. 537-542 6 p.

  Research output: Contribution to journal › Article › peer-review
  57 Scopus citations

• Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c⁺CD103⁺ Monocytic Antigen-Presenting Cells in Tumors

  Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In: Immunity. 48, 1, p. 91-106.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access
  73 Scopus citations

• Activation of particulate guanylyl cyclase by endothelins in cultured SV-40 transformed cat iris sphincter smooth muscle cells

  Ding, K. H., Latimer, A. J. & Abdel-Latif, A. A., Dec 11 1998, In: Life sciences. 64, 3, p. 161-174 14 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Activation of PERK elicits memory impairment through inactivation of CREB and downregulation of PSD95 after traumatic brain injury

  Sen, T., Gupta, R., Kaiser, H. & Sen, N., Jun 14 2017, In: Journal of Neuroscience. 37, 24, p. 5900-5911 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  56 Scopus citations

• Activation of peroxisome proliferator-activated receptor α by substituted urea-derived soluble epoxide hydrolase inhibitors

  Fang, X., Hu, S., Watanabe, T., Weintraub, N. L., Snyder, G. D., Yao, J., Liu, Y., Shyy, J. Y. J., Hammock, B. D. & Spector, A. A., Jul 2005, In: Journal of Pharmacology and Experimental Therapeutics. 314, 1, p. 260-270 11 p.

  Research output: Contribution to journal › Article › peer-review
  60 Scopus citations

• Activation of platelet-derived growth factor (PDGF) receptor-operated Ca²⁺ channel via tyrosine kinase and ras in mesangial cells

  Ma, H., Matsunaga, H., Li, B., Marrero, M. B., Eaton, D. C. & Ling, B. N., 1996, In: FASEB Journal. 10, 3, p. A139

  Research output: Contribution to journal › Article › peer-review

• Activation of postsynaptic GABA_B receptors modulate the firing activity of supraoptic oxytocin and vasopressin neurones: Role of calcium channels

  Li, Y. & Stern, J. E., Feb 1 2004, In: Journal of Neuroendocrinology. 16, 2, p. 119-130 12 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

  Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., Feb 2005, In: Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Activation of prostaglandin E₂ EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes

  Rutkai, I., Feher, A., Erdei, N., Henrion, D., Papp, Z., Edes, I., Koller, A., Kaley, G. & Bagi, Z., Jul 2009, In: Cardiovascular Research. 83, 1, p. 148-154 7 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Activation of protein kinase c by a mild burst of oxygen free radicals results in increased endogenous antioxidant enzyme activity and ameliorates post-anoxic damage in isolated myocytes

  Zhou, X., Zhai, X. & Ashraf, M., Dec 1 1996, In: FASEB Journal. 10, 3

  Research output: Contribution to journal › Article › peer-review

• Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta

  Jin, L., Ying, Z. & Webb, R. C., Oct 2004, In: American Journal of Physiology - Heart and Circulatory Physiology. 287, 4 56-4, p. H1495-H1500

  Research output: Contribution to journal › Article › peer-review
  210 Scopus citations

• Activation of Rho is Required for Ligand-independent Oncogenic Signaling by a Mutant Epidermal Growth Factor Receptor

  Boerner, J. L., Danielsen, A., McManus, M. J. & Maihle, N. J., Feb 2 2001, In: Journal of Biological Chemistry. 276, 5, p. 3691-3695 5 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Activation of sickle red blood cell adhesion via integrin-associated protein/CD47-induced signal transduction

  Brittain, J. E., Mlinar, K. J., Anderson, C. S., Orringer, E. P. & Parise, L. V., 2001, In: Journal of Clinical Investigation. 107, 12, p. 1555-1562 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  86 Scopus citations

• Activation of sigma 1 receptor extends survival of cones and improves visual acuity in a murine model of retinitis pigmentosa

  Wang, J., Saul, A. & Smith, S. B., Oct 1 2019, In: Investigative Ophthalmology and Visual Science. 60, 13, p. 4397-4407 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Scopus citations