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• Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma

  Zhou, Q., Lui, V. W. Y. & Yeo, W., Oct 2011, In: Future Oncology. 7, 10, p. 1149-1167 19 p.

  Research output: Contribution to journal › Review article › peer-review
  187 Scopus citations

• Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline

  Wang, D., Jacobs, S. A. & Tsien, J. Z., Oct 1 2014, In: Expert Opinion on Therapeutic Targets. 18, 10, p. 1121-1130 10 p.

  Research output: Contribution to journal › Review article › peer-review
  42 Scopus citations

• Targeting the MYC oncogene in burkitt lymphoma through HSP90 inhibition

  Poole, C. J., Zheng, W., Lee, H., Young, D., Lodh, A., Chadli, A. & Van Riggelen, J., Nov 16 2018, In: Cancers. 10, 11, 448.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Targeting the most important complications in vascular surgery

  Bennett, K. M., Kent, K. C., Schumacher, J., Greenberg, C. C. & Scarborough, J. E., Mar 1 2017, In: Journal of Vascular Surgery. 65, 3, p. 793-803 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations

• Targeting the Mitochondrial Permeability Transition Pore to Prevent Age-Associated Cell Damage and Neurodegeneration

  Kent, A. C., El Baradie, K. B. Y. & Hamrick, M. W., 2021, In: Oxidative medicine and cellular longevity. 2021, 6626484.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  13 Scopus citations

• Targeting the kinase activity of the BCR-ABL fusion protein in patients with chronic myeloid-leukemia

  Giles, F. J., Cortes, J. E. & Kantarjian, H. M., Nov 2005, In: Current Molecular Medicine. 5, 7, p. 615-623 9 p.

  Research output: Contribution to journal › Review article › peer-review
  32 Scopus citations

• Targeting the immunoregulatory indoleamine 2,3 dioxygenase pathway in immunotherapy

  Johnson, B. A., Baban, B. & L'Mellor, A., Jul 2009, In: Immunotherapy. 1, 4, p. 645-661 17 p.

  Research output: Contribution to journal › Review article › peer-review
  52 Scopus citations

• Targeting the F₁F_o ATP synthase: Modulation of the body's powerhouse and its implications for human disease

  Johnson, J. A. & Ogbi, M., Oct 2011, In: Current Medicinal Chemistry. 18, 30, p. 4684-4714 31 p.

  Research output: Contribution to journal › Review article › peer-review
  32 Scopus citations

• Targeting the endocannabinoid system: a predictive, preventive, and personalized medicine-directed approach to the management of brain pathologies

  Reddy, V., Grogan, D., Ahluwalia, M., Salles, É. L., Ahluwalia, P., Khodadadi, H., Alverson, K., Nguyen, A., Raju, S. P., Gaur, P., Braun, M., Vale, F. L., Costigliola, V., Dhandapani, K., Baban, B. & Vaibhav, K., Jun 1 2020, In: EPMA Journal. 11, 2, p. 217-250 34 p.

  Research output: Contribution to journal › Review article › peer-review
  18 Scopus citations

• Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

  Nhili, R., Peixoto, P., Depauw, S., Flajollet, S., Dezitter, X., Munde, M. M., Ismail, M. A., Kumar, A., Farahat, A. A., Stephens, C. E., Duterque-Coquillaud, M., David Wilson, W., Boykin, D. W. & David-Cordonnier, M. H., Jan 2013, In: Nucleic Acids Research. 41, 1, p. 125-138 14 p.

  Research output: Contribution to journal › Article › peer-review
  55 Scopus citations

• Targeting T-cell malignancies using anti-CD4 CAR NK-92 cells

  Pinz, K. G., Yakaboski, E., Jares, A., Liu, H., Firor, A. E., Chen, K. H., Wada, M., Salman, H. S., Tse, W., Hagag, N., Lan, F., Leung, E. L. H., Jiang, X. & Ma, Y., 2017, In: Oncotarget. 8, 68, p. 112783-112796 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  62 Scopus citations

• Targeting surgical site infection-reducing bundles selectively to at-risk colon cancer surgery populations achieving value in amacraworld?

  Albo, D., Jul 1 2017, In: JAMA Surgery. 152, 7, 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy

  Hong, Z., Liu, T., Wan, L., Fa, P., Kumar, P., Cao, Y., Prasad, C. B., Qiu, Z., Liu, J., Wang, H., Li, Z., Wang, Q. E., Guo, P., Guo, D., Yilmaz, A. S., Lu, L., Papandreou, I., Jacob, N. K., Yan, C., Zhang, X., & 3 othersShe, Q. B., Ma, Z. & Zhang, J., Apr 1 2022, In: Cancer Research. 82, 7, p. 1298-1312 15 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Targeting sources of superoxide and increasing nitric oxide bioavailability in hypertension

  Elmarakby, A. A., Williams, J. M. & Pollock, D. M., Mar 1 2003, In: Current Opinion in Investigational Drugs. 4, 3, p. 282-290 9 p.

  Research output: Contribution to journal › Review article › peer-review
  9 Scopus citations

• Targeting serum glucocorticoid-regulated kinase-1 in squamous cell carcinoma of the head and neck: A novel modality of local control

  Berdel, H. O., Yin, H., Liu, J. Y., Grochowska, K., Middleton, C., Yanasak, N. E., Abdelsayed, R. A., Berdel, W. E., Mozaffari, M. S., Yu, J. C. & Baban, B., Dec 8 2014, In: PloS one. 9, 12, e113795.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Targeting ros-mediated crosstalk between autophagy and apoptosis in cancer

  Gao, L., Loveless, J., Shay, C. & Teng, Y., 2020, Advances in Experimental Medicine and Biology. Springer, p. 1-12 12 p. (Advances in Experimental Medicine and Biology; vol. 1260).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  47 Scopus citations

• Targeting ras activity prevented amyloid beta-induced aberrant neuronal cell cycle re-entry and death

  Köseoğlu, M. M., Özdilek, B. A., Djakbarova, U. & Gülüşür, A., Nov 1 2016, In: Current Alzheimer Research. 13, 11, p. 1267-1276 10 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress

  Zhang, Y., Lai, J., Du, Z., Gao, J., Yang, S., Gorityala, S., Xiong, X., Deng, O., Ma, Z., Yan, C., Susana, G., Xu, Y. & Zhang, J., Jun 7 2016, In: Oncotarget. 7, 23, p. 34688-34702 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Scopus citations

• Targeting Proteasome worsens atherosclerosis

  Fukai, T., Oct 2007, In: Circulation research. 101, 9, p. 859-861 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  10 Scopus citations

• Targeting proliferative retinopathy: Arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair

  Fouda, A. Y., Xu, Z., Suwanpradid, J., Rojas, M., Shosha, E., Lemtalsi, T., Patel, C., Xing, J., Zaidi, S. A., Zhi, W., Stansfield, B. K., Cheng, P. N. M., Narayanan, S. P., Caldwell, R. W. & Caldwell, R. B., Aug 2022, In: Cell Death and Disease. 13, 8, 745.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting polyamine oxidase to prevent excitotoxicity-induced retinal neurodegeneration

  Pichavaram, P., Palani, C. D., Patel, C., Xu, Z., Shosha, E., Fouda, A. Y., Caldwell, R. B. & Narayanan, S. P., 2019, In: Frontiers in Neuroscience. 13, JAN, 956.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

  Paz, K., Flynn, R., Du, J., Tannheimer, S., Johnson, A. J., Dong, S., Stark, A. K., Okkenhaug, K., Panoskaltsis-Mortari, A., Sage, P. T., Sharpe, A. H., Luznik, L., Ritz, J., Soiffer, R. J., Cutler, C. S., Koreth, J., Antin, J. H., Miklos, D. B., MacDonald, K. P., Hill, G. R., & 10 othersMaillard, I., Serody, J. S., Murphy, W. J., Munn, D. H., Feser, C., Zaiken, M., Vanhaesebroeck, B., Turka, L. A., Byrd, J. C. & Blazar, B. R., Jun 2019, In: American Journal of Transplantation. 19, 6, p. 1820-1830 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Targeting phosphorylated p53 to elicit tumor-reactive T helper responses against head and neck squamous cell carcinoma

  Ohara, K., Ohkuri, T., Kumai, T., Nagato, T., Nozaki, Y., Ishibashi, K., Kosaka, A., Nagata, M., Harabuchi, S., Ohara, M., Oikawa, K., Aoki, N., Harabuchi, Y., Celis, E. & Kobayashi, H., Sep 2 2018, In: OncoImmunology. 7, 9, e1466771.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Targeting oncogenic ALK and MET: A promising therapeutic strategy for glioblastoma

  Wallace, G. C., Dixon-Mah, Y. N., Vandergrift, W. A., Ray, S. K., Haar, C. P., Mittendorf, A. M., Patel, S. J., Banik, N. L., Giglio, P. & Das, A., Sep 2013, In: Metabolic Brain Disease. 28, 3, p. 355-366 12 p.

  Research output: Contribution to journal › Review article › peer-review
  14 Scopus citations

• Targeting of pancreatic and prostate cancer stem cell characteristics by Crambe crambe marine sponge extract

  Ottinger, S., Klöppel, A., Rausch, V., Liu, L., Kallifatidis, G., Gross, W., Gebhard, M. M., Brümmer, F. & Herr, I., Apr 1 2012, In: International Journal of Cancer. 130, 7, p. 1671-1681 11 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release

  Fulton, D., Babbitt, R., Zoellner, S., Fontana, J., Acevedo, L., McCabe, T. J., Iwakiri, Y. & Sessa, W. C., Jul 16 2004, In: Journal of Biological Chemistry. 279, 29, p. 30349-30357 9 p.

  Research output: Contribution to journal › Article › peer-review
  108 Scopus citations

• Targeting of DC-SIGN on human dendritic cells by minor fimbriated Porphyromonas gingivalis strains elicits a distinct effector T cell response

  Zeituni, A. E., Jotwani, R., Carrion, J. & Cutler, C. W., Nov 1 2009, In: Journal of Immunology. 183, 9, p. 5694-5704 11 p.

  Research output: Contribution to journal › Article › peer-review
  60 Scopus citations

• Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma

  Salnikov, A. V., Groth, A., Apel, A., Kallifatidis, G., Beckermann, B. M., Khamidjanov, A., Ryschich, E., Büchler, M. W., Herr, I. & Moldenhauer, G., Sep 2009, In: Journal of Cellular and Molecular Medicine. 13, 9 B, p. 4023-4033 11 p.

  Research output: Contribution to journal › Article › peer-review
  37 Scopus citations

• Targeting of 12/15-Lipoxygenase in retinal endothelial cells, but not in monocytes/macrophages, attenuates high glucose-induced retinal leukostasis

  Ibrahim, A. S., Saleh, H., El-Shafey, M., Hussein, K. A., El-Masry, K., Baban, B., Sheibani, N., Wang, M. H., Tawfik, A. & Al-Shabrawey, M., Jun 1 2017, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1862, 6, p. 636-645 10 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Targeting nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of parkinson's disease

  Kaidery, N. A., Banerjee, R., Yang, L., Smirnova, N. A., Hushpulian, D. M., Liby, K. T., Williams, C. R., Yamamoto, M., Kensler, T. W., Ratan, R. R., Sporn, M. B., Beal, M. F., Gazaryan, I. G. & Thomas, B., Jan 10 2013, In: Antioxidants and Redox Signaling. 18, 2, p. 139-157 19 p.

  Research output: Contribution to journal › Article › peer-review
  125 Scopus citations

• Targeting neuropilin-1 in human leukemia and lymphoma

  Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C. E., Zurita, A. J., Kuniyasu, A., Eckhardt, B. L., Marini, F. C., Lichtiger, B., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Koivunen, E., Arap, W. & Pasqualini, R., Jan 20 2011, In: Blood. 117, 3, p. 920-927 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  86 Scopus citations

• Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function

  Sagar, A., Arif, E., Solanki, A. K., Srivastava, P., Janech, M. G., Kim, S. H., Lipschutz, J. H., Kwon, S. H., Ashish & Nihalani, D., Dec 1 2017, In: Scientific reports. 7, 1, 12047.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  16 Scopus citations

• Targeting neovascularization in ischemic retinopathy: Recent advances

  Al-Shabrawey, M., Elsherbiny, M., Nussbaum, J., Othman, A., Megyerdi, S. & Tawfik, A., Jun 2013, In: Expert Review of Ophthalmology. 8, 3, p. 267-286 20 p.

  Research output: Contribution to journal › Review article › peer-review
  30 Scopus citations

• Targeting neddylation E2 for anticancer therapy, putting new wine into new bottles?

  Zou, J. & Su, H., Jul 2019, In: EBioMedicine. 45, p. 3-4 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  1 Scopus citations

• Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease

  Bachmann, C., Klibanov, A. L., Olson, T. S., Sonnenschein, J. R., Rivera-Nieves, J., Cominelli, F., Ley, K. F., Lindner, J. R. & Pizarro, T. T., Jan 2006, In: Gastroenterology. 130, 1, p. 8-16 9 p.

  Research output: Contribution to journal › Article › peer-review
  99 Scopus citations

• Targeting mitochondrial metabolism in prostate cancer with triterpenoids

  Mamouni, K., Kallifatidis, G. & Lokeshwar, B. L., Mar 1 2021, In: International journal of molecular sciences. 22, 5, p. 1-15 15 p., 2466.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  10 Scopus citations

• Targeting metastatic breast cancer with ANG1005, a novel peptide-paclitaxel conjugate that crosses the blood-brain-barrier (BBB)

  Li, F. & Tang, S. C., Mar 1 2017, In: Genes and Diseases. 4, 1, p. 1-3 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
  21 Scopus citations

• Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers

  Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E., Melnik, M. K., Korkaya, H., Maroun, C. R., Christensen, J. G., Steensma, M. R., Boerner, J. L. & Graveel, C. R., 2016, In: Oncotarget. 7, 43, p. 69903-69915 13 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Targeting lymphotoxin β receptor with tumor-specific T lymphocytes for tumor regression

  Yang, D., Ud Din, N., Browning, D. D., Abrams, S. I. & Liu, K., Sep 1 2007, In: Clinical Cancer Research. 13, 17, p. 5202-5210 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  19 Scopus citations

• Targeting insomnia symptoms as a path to reduction of suicide risk: the role of cognitive behavioral therapy for insomnia (CBT-I): the role of cognitive behavioral therapy for insomnia (CBT-I)

  McCall, W. V., Dec 12 2022, In: Sleep. 45, 12

  Research output: Contribution to journal › Article › peer-review

• Targeting IL11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens

  Karjalainen, K., Jaalouk, D. E., Bueso-Ramos, C., Bover, L., Sun, Y., Kuniyasu, A., Driessen, W. H. P., Cardó-Vila, M., Rietz, C., Zurita, A. J., O'Brien, S., Kantarjian, H. M., Cortes, J. E., Calin, G. A., Koivunen, E., Arap, W. & Pasqualini, R., Jul 1 2015, In: Clinical Cancer Research. 21, 13, p. 3041-3051 11 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Targeting hypoxia-driven metabolic reprogramming to constrain tumor progression and metastasis

  Miranda-Galvis, M. & Teng, Y., Aug 1 2020, In: International journal of molecular sciences. 21, 15, p. 1-17 17 p., 5487.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  18 Scopus citations

• Targeting hyaluronidase for cancer therapy: Antitumor activity of sulfated hyaluronic acid in prostate cancer cells

  Benitez, A., Yates, T. J., Lopez, L. E., Cerwinka, W. H., Bakkar, A. & Lokeshwar, V. B., Jun 15 2011, In: Cancer Research. 71, 12, p. 4085-4095 11 p.

  Research output: Contribution to journal › Article › peer-review
  109 Scopus citations

• Targeting hyaluronic acid synthase-3 (HAS3) for the treatment of advanced renal cell carcinoma

  Wang, J., Jordan, A. R., Zhu, H., Hasanali, S. L., Thomas, E., Lokeshwar, S. D., Morera, D. S., Alexander, S., McDaniels, J., Sharma, A., Aguilar, K., Sarcan, S., Zhu, T., Soloway, M. S., Terris, M. K., Thangaraju, M., Lopez, L. E. & Lokeshwar, V. B., Dec 2022, In: Cancer Cell International. 22, 1, 421.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting hyaluronic acid family for cancer chemoprevention and therapy

  Lokeshwar, V. B., Mirza, S. & Jordan, A., 2014, Advances in Cancer Research. Academic Press Inc., p. 35-65 31 p. (Advances in Cancer Research; vol. 123).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  107 Scopus citations

• Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia

  Ganguly, S., Home, T., Yacoub, A., Kambhampati, S., Shi, H., Dandawate, P., Padhye, S., Saluja, A. K., McGuirk, J. & Rao, R., 2015, In: Oncotarget. 6, 31, p. 31767-31779 13 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation

  Woan, K. V., Lienlaf, M., Perez-Villaroel, P., Lee, C., Cheng, F., Knox, T., Woods, D. M., Barrios, K., Powers, J., Sahakian, E., Wang, H. W., Canales, J., Marante, D., Smalley, K. S. M., Bergman, J., Seto, E., Kozikowski, A., Pinilla-Ibarz, J., Sarnaik, A., Celis, E., & 3 othersWeber, J., Sotomayor, E. M. & Villagra, A., Aug 1 2015, In: Molecular Oncology. 9, 7, p. 1447-1457 11 p.

  Research output: Contribution to journal › Article › peer-review
  88 Scopus citations

• Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma

  Kumai, T., Ohkuri, T., Nagato, T., Matsuda, Y., Oikawa, K., Aoki, N., Kimura, S., Celis, E., Harabuchi, Y. & Kobayashi, H., Nov 5 2015, In: Scientific reports. 5, 16280.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option

  Starlard-Davenport, A., Gu, Q. & Pace, B. S., Sep 2022, In: Molecular Diagnosis and Therapy. 26, 5, p. 497-509 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  3 Scopus citations

• Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models

  Wu, Q., Bhole, A., Qin, H., Karp, J., Malek, S., Cowell, J. K. & Ren, M., 2016, In: Oncotarget. 7, 31, p. 49733-49742 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations