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• 2020

  AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia

  Poh, L., Fann, D. Y., Wong, P., Lim, H. M., Foo, S. L., Kang, S. W., Rajeev, V., Selvaraji, S., Iyer, V. R., Parathy, N., Khan, M. B., Hess, D. C., Jo, D. G., Drummond, G. R., Sobey, C. G., Lai, M. K. P., Chen, C. L. H., Lim, L. H. K. & Arumugam, T. V., 2020, (Accepted/In press) In: Molecular Psychiatry.

  Research output: Contribution to journal › Article › peer-review

  • Inflammasomes
  • Vascular Dementia
  • Cognitive Dysfunction
  • Pyroptosis
  • Carotid Stenosis

• A multicentre, randomised, sham-controlled trial on REmote iSchemic conditioning In patients with acute STroke (RESIST) – Rationale and study design

  Blauenfeldt, R. A., Hjort, N., Gude, M. F., Behrndtz, A. B., Fisher, M., Valentin, J. B., Kirkegaard, H., Johnsen, S. P., Hess, D. C. & Andersen, G., Mar 1 2020, In: European Stroke Journal. 5, 1, p. 94-101 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stroke
  • Randomized Controlled Trials
  • Cerebral Hemorrhage
  • Economic Inflation
  • Blood Pressure
  1 Scopus citations

• Cannabidiol (CBD) modulation of apelin in acute respiratory distress syndrome

  Salles, É. L., Khodadadi, H., Jarrahi, A., Ahluwalia, M., Paffaro, V. A., Costigliola, V., Yu, J. C., Hess, D. C., Dhandapani, K. M. & Baban, B., Nov 2020, In: Journal of Cellular and Molecular Medicine. 24, 21, p. 12869-12872 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apelin
  • Cannabidiol
  • Adult Respiratory Distress Syndrome
  • Poly I-C
  • Therapeutics
  2 Scopus citations

• Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA

  Khodadadi, H., Salles, É. L., Jarrahi, A., Chibane, F., Costigliola, V., Yu, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M. & Baban, B., Sep 1 2020, In: Cannabis and Cannabinoid Research. 5, 3, p. 197-201 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Cannabidiol
  • Adult Respiratory Distress Syndrome
  • Virus Diseases
  • RNA
  • Cytokines
  6 Scopus citations

• COVID-19-Related Stroke

  Hess, D. C., Eldahshan, W. & Rutkowski, E., Jun 1 2020, In: Translational Stroke Research. 11, 3, p. 322-325 4 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • angiotensin converting enzyme 2
  • SARS Virus
  • Angiotensin II
  • Stroke
  • Peptidyl-Dipeptidase A
  101 Scopus citations

• Establishment of an internationally agreed minimum data set for acute telestroke

  Cadilhac, D. A., Bagot, K. L., Demaerschalk, B. M., Hubert, G., Schwamm, L., Watkins, C. L., Lightbody, C. E., Kim, J., Vu, M., Pompeani, N., Switzer, J., Caudill, J., Estrada, J., Viswanathan, A., Hubert, N., Ohannessian, R., Hargroves, D., Roberts, N., Ingall, T., Hess, D. C. & 3 others, Ranta, A., Padma, V. & Bladin, C. F., 2020, (Accepted/In press) In: Journal of Telemedicine and Telecare.

  Research output: Contribution to journal › Article › peer-review

  • Datasets
  • Australasia
  • Referral and Consultation
  • Telecommunications
  • Delphi Technique
  3 Scopus citations

• Neurological consequences of COVID-19: What have we learned and where do we go from here?

  Jarrahi, A., Ahluwalia, M., Khodadadi, H., Da Silva Lopes Salles, E., Kolhe, R., Hess, D. C., Vale, F., Kumar, M., Baban, B., Vaibhav, K. & Dhandapani, K. M., Sep 30 2020, In: Journal of Neuroinflammation. 17, 1, 286.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus
  • SARS Virus
  • Dysgeusia
  • Middle East Respiratory Syndrome Coronavirus
  • Respiratory Center
  6 Scopus citations

• Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury

  Vaibhav, K., Braun, M., Alverson, K., Khodadadi, H., Kutiyanawalla, A., Ward, A., Banerjee, C., Sparks, T., Malik, A., Rashid, M. H., Rashid, M. H., Khan, M. B., Waters, M. F., Hess, D. C., Arbab, A. S., Vender, J. R., Hoda, N., Hoda, N., Hoda, N., Baban, B. & 3 others, Baban, B., Baban, B. & Dhandapani, K. M., May 2020, In: Science Advances. 6, 22, EAAX8847.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Traps
  • Traumatic Brain Injury
  • Deoxyribonuclease I
  • dornase alfa
  • Protein-Arginine Deiminases
  4 Scopus citations

• Short-Term Acute Exercise Preconditioning Reduces Neurovascular Injury After Stroke Through Induced eNOS Activation

  Hafez, S., Khan, M. B., Awad, M. E., Wagner, J. D. & Hess, D. C., Aug 1 2020, In: Translational Stroke Research. 11, 4, p. 851-860 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Exercise
  • Wounds and Injuries
  • Neuroprotection
  • N(G)-iminoethylornithine
  1 Scopus citations

• The Association Between Stroke Mortality and Time of Admission and Participation in a Telestroke Network

  Witrick, B., Zhang, D., Switzer, J. A., Hess, D. C. & Shi, L., Feb 2020, In: Journal of Stroke and Cerebrovascular Diseases. 29, 2, 104480.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Mortality
  • Hospital Mortality
  • Hospital Bed Capacity
  • Registries
  3 Scopus citations
• 2019

  Impact of Participation in a Telestroke Network on Clinical Outcomes

  Zhang, D., Shi, L., Ido, M. S., Green, D. E., Li, Y., Su, D. & Hess, D. C., Jan 1 2019, In: Circulation. Cardiovascular quality and outcomes. 12, 1, p. e005147

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Tissue Plasminogen Activator
  • Propensity Score
  • Observational Studies
  • Hospital Bed Capacity
  9 Scopus citations
• 2018

  Chronic Remote Ischemic Conditioning Is Cerebroprotective and Induces Vascular Remodeling in a VCID Model

  Khan, M. B., Hafez, S., Hoda, M. N., Baban, B., Wagner, J., Awad, M. E., Sangabathula, H., Haigh, S., Elsalanty, M., Waller, J. L. & Hess, D. C., Feb 1 2018, In: Translational Stroke Research. 9, 1, p. 51-63 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Remodeling
  • Carotid Stenosis
  • Conditioning (Psychology)
  • Dementia
  • Cognitive Dysfunction
  17 Scopus citations

• Expansion of telestroke services improves quality of care provided in super rural areas

  Zhang, D., Wang, G., Zhu, W., Thapa, J. R., Switzer, J. A., Hess, D. C., Smith, M. L. & Ritchey, M. D., Dec 2018, In: Health Affairs. 37, 12, p. 2005-2013 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Quality of Health Care
  • Tissue Plasminogen Activator
  • Stroke
  • Thrombectomy
  • Fee-for-Service Plans
  6 Scopus citations

• Human neural stem cell extracellular vesicles improve recovery in a porcine model of ischemic stroke

  Webb, R. L., Kaiser, E. E., Jurgielewicz, B. J., Spellicy, S., Scoville, S. L., Thompson, T. A., Swetenburg, R. L., Hess, D. C., West, F. D. & Stice, S. L., 2018, In: Stroke. 49, 5, p. 1248-1256 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles
  • Neural Stem Cells
  • Swine
  • Middle Cerebral Artery Infarction
  • Stroke
  69 Scopus citations

• Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model

  Webb, R. L., Kaiser, E. E., Scoville, S. L., Thompson, T. A., Fatima, S., Pandya, C., Sriram, K., Swetenburg, R. L., Vaibhav, K., Arbab, A. S., Baban, B., Dhandapani, K. M., Hess, D. C., Hoda, M. N. & Stice, S. L., Oct 1 2018, In: Translational Stroke Research. 9, 5, p. 530-539 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Vesicles
  • Neural Stem Cells
  • Stroke
  • Rodentia
  • Mesenchymal Stem Cells
  52 Scopus citations

• Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation

  Vaibhav, K., Braun, M., Khan, M. B., Fatima, S., Saad, N., Shankar, A., Khan, Z. T., Harris, R. B. S., Yang, Q., Huo, Y., Arbab, A. S., Giri, S., Alleyne, C. H., Vender, J. R., Hess, D. C., Baban, B., Hoda, M. N. & Dhandapani, K. M., Oct 1 2018, In: Journal of Experimental Medicine. 215, 10, p. 2636-2654 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ischemic Postconditioning
  • Hematoma
  • Extremities
  • Cerebral Hemorrhage
  • Metabolic Inactivation
  19 Scopus citations

• Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization

  Braun, M., Khan, Z. T., Khan, M. B., Kumar, M., Ward, A., Achyut, B. R., Arbab, A. S., Hess, D. C., Hoda, M. N., Baban, B., Dhandapani, K. M. & Vaibhav, K., Feb 2018, In: Brain, Behavior, and Immunity. 68, p. 224-237 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cannabinoid Receptors
  • Traumatic Brain Injury
  • Macrophages
  • Endocannabinoids
  • iodopravadoline
  30 Scopus citations

• Stem Cell Therapy in Cerebrovascular Disease

  Nahhas, M. I. & Hess, D. C., Nov 1 2018, In: Current Treatment Options in Neurology. 20, 11, 49.

  Research output: Contribution to journal › Review article › peer-review

  • Cerebrovascular Disorders
  • Cell- and Tissue-Based Therapy
  • Stem Cells
  • Clinical Trials
  • Stroke
  3 Scopus citations
• 2017

  Collaterals 2016: Translating the collaterome around the globe

  for the Collaterals 2016 Consortium, Jun 2017, In: International Journal of Stroke. 12, 4, p. 338-342 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke
  • Congresses
  • Videoconferencing
  • Collateral Circulation
  • Triage
  3 Scopus citations

• Induced Pluripotent Stem Cell-Derived Neural Stem Cell Therapy Enhances Recovery in an Ischemic Stroke Pig Model

  Baker, E. W., Platt, S. R., Lau, V. W., Grace, H. E., Holmes, S. P., Wang, L., Duberstein, K. J., Howerth, E. W., Kinder, H. A., Stice, S. L., Hess, D. C., Mao, H. & West, F. D., Dec 1 2017, In: Scientific reports. 7, 1, 10075.

  Research output: Contribution to journal › Article › peer-review

  • Induced Pluripotent Stem Cells
  • Neural Stem Cells
  • Cell- and Tissue-Based Therapy
  • Swine
  • Stroke
  39 Scopus citations

• Minocycline in acute cerebral hemorrhage an early phase randomized trial

  Fouda, A. Y., Newsome, A. S., Spellicy, S., Waller, J. L., Zhi, W., Hess, D. C., Ergul, A., Edwards, D. J., Fagan, S. C. & Switzer, J. A., Oct 2017, In: Stroke. 48, 10, p. 2885-2887 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Minocycline
  • Cerebral Hemorrhage
  • Half-Life
  • Pharmacokinetics
  • Anti-Inflammatory Agents
  25 Scopus citations

• Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial

  Hess, D. C., Wechsler, L. R., Clark, W. M., Savitz, S. I., Ford, G. A., Chiu, D., Yavagal, D. R., Uchino, K., Liebeskind, D. S., Auchus, A. P., Sen, S., Sila, C. A., Vest, J. D. & Mays, R. W., May 2017, In: The Lancet Neurology. 16, 5, p. 360-368 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Stem Cells
  • Placebos
  • Stroke
  • Safety
  • National Institutes of Health (U.S.)
  120 Scopus citations

• Telemedicine quality and outcomes in stroke: A scientific statement for healthcare professionals from the American Heart Association/American Stroke Association

  Wechsler, L. R., Demaerschalk, B. M., Schwamm, L. H., Adeoye, O. M., Audebert, H. J., Fanale, C. V., Hess, D. C., Majersik, J. J., Nystrom, K. V., Reeves, M. J., Rosamond, W. D. & Switzer, J. A., Jan 1 2017, In: Stroke. 48, 1, p. e3-e25

  Research output: Contribution to journal › Article › peer-review

  • Telemedicine
  • American Heart Association
  • Committee Membership
  • Stroke
  • Delivery of Health Care
  102 Scopus citations
• 2016

  Addressing Disparities in Stroke Prevention for Atrial Fibrillation: Educational Opportunities

  Karcher, R., Berman, A. E., Gross, H., Hess, D. C., Jauch, E. C., Viser, P. E., Solenski, N. J. & Wolf, A. M. D., Jul 1 2016, In: American Journal of Medical Quality. 31, 4, p. 337-348 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Atrial Fibrillation
  • Stroke
  • Anticoagulants
  • Communication
  • Racism
  4 Scopus citations

• Humoral mediators of remote ischemic conditioning: Important role of eNOS/NO/nitrite

  Hess, D. C., Hoda, M. N. & Khan, M. B., 2016, Acta Neurochirurgica, Supplementum. Springer-Verlag Wien, p. 45-48 4 p. (Acta Neurochirurgica, Supplementum; vol. 121).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  18 Scopus citations

• Lab-to-clinic application of stem cell therapy for stroke

  Borlongan, M. C., Kong, S. & Hess, D. C., Oct 3 2016, In: Chinese Neurosurgical Journal. 2, 1, 42.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cell- and Tissue-Based Therapy
  • Stem Cells
  • Stroke
  • Bone Marrow Cells
  • Clinical Trials
  1 Scopus citations

• Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke

  STAIR IX Collaborators, Aug 1 2016, In: Stroke. 47, 8, p. 2154-2159 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Industry
  • Meta-Analysis
  • Data Analysis
  • Stroke
  • Authorship
  4 Scopus citations